Domain motion and interdomain hot spots in a multidomain enzyme

Protein Science

Volumn 19, Issue 9, 2010, Pages 1662-1672

  Chuang, Gwo Yu ^a   Mehra Chaudhary, Ritcha ^b   Ngan, Chi Ho ^a   Zerbe, Brandon S ^a   Kozakov, Dima ^a   Vajda, Sandor ^a,c   Beamer, Lesa J ^b  

^a Boston University   (United States)

^b University of Missouri   (United States)

^c Boston University   (United States)

Author keywords

Allostery; Computational solvent mapping; Conformational change; Free energy landscape; Hinge bending; Ligand binding pocket; Structure comparison; X ray crystallography

Indexed keywords

ENZYME; FUNCTIONAL GROUP; GLUCOSE; GLUCOSE 1 PHOSPHATE; GLUCOSE 6 PHOSPHATE; LIGAND; MANNOSE; OXYGEN; PHOSPHOGLUCOMUTASE; PHOSPHOMANNOMUTASE; PROTEIN; SUGAR PHOSPHATE;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; COMPUTATIONAL FLUID DYNAMICS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME LOCALIZATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; LIGAND BINDING; MOLECULAR PROBE; MOLECULE; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PSEUDOMONAS AERUGINOSA; X RAY CRYSTALLOGRAPHY;

CATALYTIC DOMAIN; LIGANDS; MODELS, MOLECULAR; PHOSPHOGLUCOMUTASE; PHOSPHOTRANSFERASES (PHOSPHOMUTASES); PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA;

PSEUDOMONAS AERUGINOSA;

EID: 77956354062     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.446     Document Type: Article

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