Crystal structure of PMM/PGM: An enzyme in the biosynthetic pathway of P. aeruginosa virulence factors

Structure

Volumn 10, Issue 2, 2002, Pages 269-279

  Regni, Catherine ^a   Tipton, Peter A ^a   Beamer, Lesa J ^a  

^a University of Missouri   (United States)

Author keywords

Alginate; Biofilm; Cystic fibrosis; P. aeruginosa; Phoshpohexomutase; X ray crystallography

Indexed keywords

ALGINIC ACID; CARBOHYDRATE; ENZYME INHIBITOR; EXOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE; PHOSPHOGLUCOMUTASE; PHOSPHOMANNOMUTASE; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL INFECTION; BIOSYNTHESIS; CARBOHYDRATE SYNTHESIS; CRYSTAL STRUCTURE; CYSTIC FIBROSIS; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG SPECIFICITY; ENZYME ACTIVE SITE; IMMUNE SYSTEM; LUNG INFECTION; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PSEUDOMONAS AERUGINOSA; STRUCTURE ANALYSIS;

ANIMALS; BINDING SITES; CARBOHYDRATE METABOLISM; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; ELECTROSTATICS; ENZYME INHIBITORS; MAGNESIUM; MODELS, MOLECULAR; MUTATION; PHOSPHATES; PHOSPHOGLUCOMUTASE; PHOSPHOTRANSFERASES (PHOSPHOMUTASES); PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA; RABBITS; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; TARTRATES; VIRULENCE;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 0036174748     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(02)00705-0     Document Type: Article

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