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Volumn 24, Issue 5, 2010, Pages 815-835

Upper gastrointestinal cancer predisposition syndromes

Author keywords

Cancer; Gastrointestinal; Genetic predisposition; Hereditary; Malignancy

Indexed keywords

ARGININE; BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; BRCA2 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYTOGLOBIN; HISTIDINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN MLH1; PROTEIN MSH2; UVOMORULIN;

EID: 77956301557     PISSN: 08898588     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hoc.2010.06.007     Document Type: Review
Times cited : (12)

References (142)
  • 1
    • 0026028040 scopus 로고
    • Rising incidence of adenocarcinoma of the esophagus and gastric cardia
    • Blot W.J., DeVesa S.S., Kneller R.W., et al. Rising incidence of adenocarcinoma of the esophagus and gastric cardia. JAMA 1991, 265:1287-1289.
    • (1991) JAMA , vol.265 , pp. 1287-1289
    • Blot, W.J.1    DeVesa, S.S.2    Kneller, R.W.3
  • 2
    • 0032756946 scopus 로고    scopus 로고
    • The changing epidemiology of esophageal cancer
    • Blot W.J., McLaughlin J.K. The changing epidemiology of esophageal cancer. Semin Oncol 1999, 26:2-13.
    • (1999) Semin Oncol , vol.26 , pp. 2-13
    • Blot, W.J.1    McLaughlin, J.K.2
  • 3
    • 51049091878 scopus 로고    scopus 로고
    • Incidence of adenocarcinoma of the esophagus among white Americans by sex, stage, and age
    • Brown L.M., Devesa S.S., Chow W.H. Incidence of adenocarcinoma of the esophagus among white Americans by sex, stage, and age. J Natl Cancer Inst 2008, 100:1184-1187.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1184-1187
    • Brown, L.M.1    Devesa, S.S.2    Chow, W.H.3
  • 4
    • 33644681327 scopus 로고    scopus 로고
    • Epidemiology of gastric cancer
    • Crew K.D., Neugut A.I. Epidemiology of gastric cancer. World J Gastroenterol 2006, 12(3):354-362.
    • (2006) World J Gastroenterol , vol.12 , Issue.3 , pp. 354-362
    • Crew, K.D.1    Neugut, A.I.2
  • 5
    • 67650874081 scopus 로고    scopus 로고
    • Cancer statistics, 2009
    • Jemal A., Siegel R., Ward E., et al. Cancer statistics, 2009. CA Cancer J Clin 2009, 59(4):225-249.
    • (2009) CA Cancer J Clin , vol.59 , Issue.4 , pp. 225-249
    • Jemal, A.1    Siegel, R.2    Ward, E.3
  • 6
    • 0000299984 scopus 로고
    • Six cases of carcinoma of the oesophagus occurring in one family
    • Clarke C.A., McConnell R.B. Six cases of carcinoma of the oesophagus occurring in one family. Br Med J 1954, 2:1137-1138.
    • (1954) Br Med J , vol.2 , pp. 1137-1138
    • Clarke, C.A.1    McConnell, R.B.2
  • 7
    • 0029988982 scopus 로고    scopus 로고
    • Linkage of an American pedigree with palmo-plantar keratoderma and malignancy (palmoplantar ectodermal dysplasia type III) to 17q24. Literature survey and proposed updated classification of the keratodermas
    • Stevens H.P., Kelsell D.P., Bryant S.P., et al. Linkage of an American pedigree with palmo-plantar keratoderma and malignancy (palmoplantar ectodermal dysplasia type III) to 17q24. Literature survey and proposed updated classification of the keratodermas. Arch Dermatol 1996, 132:640-651.
    • (1996) Arch Dermatol , vol.132 , pp. 640-651
    • Stevens, H.P.1    Kelsell, D.P.2    Bryant, S.P.3
  • 8
    • 0029155863 scopus 로고
    • Palmoplantar keratoderma in association with carcinoma of the oesophagus maps to chromosome 17q distal to the keratin gene cluster
    • Hennies H.C., Hagedorn M., Reis A. Palmoplantar keratoderma in association with carcinoma of the oesophagus maps to chromosome 17q distal to the keratin gene cluster. Genomics 1995, 29:537-540.
    • (1995) Genomics , vol.29 , pp. 537-540
    • Hennies, H.C.1    Hagedorn, M.2    Reis, A.3
  • 9
    • 0028327308 scopus 로고
    • Tylosis associated with carcinoma of the oesophagus and oral leukoplakia in a large Liverpool family - a review of six generations
    • Ellis A., Field J.K., Field A.E., et al. Tylosis associated with carcinoma of the oesophagus and oral leukoplakia in a large Liverpool family - a review of six generations. Eur J Cancer B Oral Oncol 1994, 30:102-111.
    • (1994) Eur J Cancer B Oral Oncol , vol.30 , pp. 102-111
    • Ellis, A.1    Field, J.K.2    Field, A.E.3
  • 10
    • 39049102905 scopus 로고    scopus 로고
    • Genetics of gastroesophageal cancer: paradigms, paradoxes, and prognostic utility
    • Robertson E.V., Jankowski J.A. Genetics of gastroesophageal cancer: paradigms, paradoxes, and prognostic utility. Am J Gastroenterol 2008, 103:443-449.
    • (2008) Am J Gastroenterol , vol.103 , pp. 443-449
    • Robertson, E.V.1    Jankowski, J.A.2
  • 11
    • 0037068742 scopus 로고    scopus 로고
    • Characterization of a 500kb region on 17q25 and the exclusion of candidate genes as the familial tylosis oesophageal cancer (TOC) locus
    • Risk J.M., Evans K.E., Jones J., et al. Characterization of a 500kb region on 17q25 and the exclusion of candidate genes as the familial tylosis oesophageal cancer (TOC) locus. Oncogene 2002, 21:6395-6402.
    • (2002) Oncogene , vol.21 , pp. 6395-6402
    • Risk, J.M.1    Evans, K.E.2    Jones, J.3
  • 12
    • 2942729612 scopus 로고    scopus 로고
    • Novel microsatellite markers and single nucleotide polymorphisms refine the tylosis with oesophageal cancer (TOC) minimal region on 17q25 to 42.5kb: sequencing does not identify causative gene
    • Langan J.E., Cole C.G., Huckle E.J., et al. Novel microsatellite markers and single nucleotide polymorphisms refine the tylosis with oesophageal cancer (TOC) minimal region on 17q25 to 42.5kb: sequencing does not identify causative gene. Hum Genet 2004, 114:534-540.
    • (2004) Hum Genet , vol.114 , pp. 534-540
    • Langan, J.E.1    Cole, C.G.2    Huckle, E.J.3
  • 13
    • 33645823676 scopus 로고    scopus 로고
    • Down-regulation of the cytoglobin gene, located on 17q25, in tylosis with oesophageal cancer (TOC): evidence for transallele repression
    • McRonald F.E., Liloglou T., Xinarianos G., et al. Down-regulation of the cytoglobin gene, located on 17q25, in tylosis with oesophageal cancer (TOC): evidence for transallele repression. Hum Mol Genet 2006, 15:1271-1277.
    • (2006) Hum Mol Genet , vol.15 , pp. 1271-1277
    • McRonald, F.E.1    Liloglou, T.2    Xinarianos, G.3
  • 14
    • 0028141722 scopus 로고
    • Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q
    • Stratton M.R., Ford D., Neuhasen S., et al. Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q. Nat Genet 1994, 7(1):103-107.
    • (1994) Nat Genet , vol.7 , Issue.1 , pp. 103-107
    • Stratton, M.R.1    Ford, D.2    Neuhasen, S.3
  • 15
    • 0032574733 scopus 로고    scopus 로고
    • The BRC repeats in BRCA2 are critical for Rad51 binding and resistance to methyl methanesulfonate treatment
    • Chen P.L., Chen C.F., Chen Y., et al. The BRC repeats in BRCA2 are critical for Rad51 binding and resistance to methyl methanesulfonate treatment. Proc Natl Acad Sci U S A 1998, 95(9):5287-5292.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , Issue.9 , pp. 5287-5292
    • Chen, P.L.1    Chen, C.F.2    Chen, Y.3
  • 16
    • 33751278712 scopus 로고    scopus 로고
    • Cellular functions of the BRCA tumour-suppressor proteins
    • Boulton S.J. Cellular functions of the BRCA tumour-suppressor proteins. Biochem Soc Trans 2006, 34(5):633-645.
    • (2006) Biochem Soc Trans , vol.34 , Issue.5 , pp. 633-645
    • Boulton, S.J.1
  • 17
    • 1242272911 scopus 로고    scopus 로고
    • Evaluation of BRCA2 in the genetic susceptibility of familial esophageal cancer
    • Nan H., Wang C., Han X-Y., et al. Evaluation of BRCA2 in the genetic susceptibility of familial esophageal cancer. Oncogene 2004, 23:852-858.
    • (2004) Oncogene , vol.23 , pp. 852-858
    • Nan, H.1    Wang, C.2    Han, X.-Y.3
  • 18
    • 39749172428 scopus 로고    scopus 로고
    • Germline BRCA2 mutations and the risk of esophageal squamous cell carcinoma
    • Akbari M.R., Malekzadeh R., Nasrollahzadeh D., et al. Germline BRCA2 mutations and the risk of esophageal squamous cell carcinoma. Oncogene 2008, 27(9):1290-1296.
    • (2008) Oncogene , vol.27 , Issue.9 , pp. 1290-1296
    • Akbari, M.R.1    Malekzadeh, R.2    Nasrollahzadeh, D.3
  • 19
    • 0034028393 scopus 로고    scopus 로고
    • Symptomatic gastro-oesophageal reflux as a risk factor for oesophageal adenocarcinoma
    • Cameron A.J., Romero Y. Symptomatic gastro-oesophageal reflux as a risk factor for oesophageal adenocarcinoma. Gut 2000, 46(6):754-755.
    • (2000) Gut , vol.46 , Issue.6 , pp. 754-755
    • Cameron, A.J.1    Romero, Y.2
  • 20
    • 8744309168 scopus 로고    scopus 로고
    • Identification of Barrett's esophagus in relatives by endoscopic screening
    • Chak A., Faulx A., Kinnard M., et al. Identification of Barrett's esophagus in relatives by endoscopic screening. Am J Gastroenterol 2004, 99:2107-2114.
    • (2004) Am J Gastroenterol , vol.99 , pp. 2107-2114
    • Chak, A.1    Faulx, A.2    Kinnard, M.3
  • 21
    • 0042329962 scopus 로고    scopus 로고
    • Demographic and phenotypic features of 70 families segregating Barrett's esophagus and esophageal adenocarcinoma
    • Drovdlik C.M., Goddard K.A.B., Chak A., et al. Demographic and phenotypic features of 70 families segregating Barrett's esophagus and esophageal adenocarcinoma. J Med Genet 2003, 40:651-656.
    • (2003) J Med Genet , vol.40 , pp. 651-656
    • Drovdlik, C.M.1    Goddard, K.A.B.2    Chak, A.3
  • 22
    • 33846256110 scopus 로고    scopus 로고
    • Familial trends of inheritance in gastro-esophageal reflux disease, Barrett's esophagus and Barrett's adenocarcinoma: 20 families
    • Sappati Biyyani R.S., Chessler L., McCain E., et al. Familial trends of inheritance in gastro-esophageal reflux disease, Barrett's esophagus and Barrett's adenocarcinoma: 20 families. Dis Esophagus 2007, 20:53-57.
    • (2007) Dis Esophagus , vol.20 , pp. 53-57
    • Sappati Biyyani, R.S.1    Chessler, L.2    McCain, E.3
  • 23
    • 0036140724 scopus 로고    scopus 로고
    • Gastroesophageal reflux disease in monozygotic and dizygotic twins
    • Cameron A.J., Lagergren J., Henriksson C., et al. Gastroesophageal reflux disease in monozygotic and dizygotic twins. Gastroenterology 2002, 122:55-59.
    • (2002) Gastroenterology , vol.122 , pp. 55-59
    • Cameron, A.J.1    Lagergren, J.2    Henriksson, C.3
  • 24
    • 0038298411 scopus 로고    scopus 로고
    • Genetic influences in gastro-esophageal reflux disease: a twin study
    • Mohammed I., Cherkas L.F., Riley S.A., et al. Genetic influences in gastro-esophageal reflux disease: a twin study. Gut 2003, 52:1085-1089.
    • (2003) Gut , vol.52 , pp. 1085-1089
    • Mohammed, I.1    Cherkas, L.F.2    Riley, S.A.3
  • 25
    • 4243237734 scopus 로고    scopus 로고
    • Concordance of reflux among monozygotic and dizygotic twins
    • Zaman M.S., Hur C., Jones M.P., et al. Concordance of reflux among monozygotic and dizygotic twins. Gastroenterology 2001, 120(Suppl 5):A418.
    • (2001) Gastroenterology , vol.120 , Issue.SUPPL 5
    • Zaman, M.S.1    Hur, C.2    Jones, M.P.3
  • 26
    • 62949245283 scopus 로고    scopus 로고
    • Genetic variations in esophageal cancer risk and prognosis
    • Cheung W.Y., Liu G. Genetic variations in esophageal cancer risk and prognosis. Gastroenterol Clin North Am 2009, 38:75-91.
    • (2009) Gastroenterol Clin North Am , vol.38 , pp. 75-91
    • Cheung, W.Y.1    Liu, G.2
  • 27
    • 39649117978 scopus 로고    scopus 로고
    • Carcinogenetic impact of ADH1B and ALDH2 genes on squamous cell carcinoma risk of the esophagus with regard to the consumption of alcohol, tobacco, and betel quid
    • Lee C.H., Lee J.M., Wu D.C., et al. Carcinogenetic impact of ADH1B and ALDH2 genes on squamous cell carcinoma risk of the esophagus with regard to the consumption of alcohol, tobacco, and betel quid. Int J Cancer 2008, 122(6):1347-1356.
    • (2008) Int J Cancer , vol.122 , Issue.6 , pp. 1347-1356
    • Lee, C.H.1    Lee, J.M.2    Wu, D.C.3
  • 28
    • 23844550544 scopus 로고    scopus 로고
    • Alcohol, ALDH2, and esophageal cancer: a meta-analysis which illustrates the potentials and limitations of a Mendelian randomization approach
    • Lewis S.J., Smith G.D. Alcohol, ALDH2, and esophageal cancer: a meta-analysis which illustrates the potentials and limitations of a Mendelian randomization approach. Cancer Epidemiol Biomarkers Prev 2005, 14:1967-1971.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 1967-1971
    • Lewis, S.J.1    Smith, G.D.2
  • 29
    • 42149190878 scopus 로고    scopus 로고
    • Polymorphisms in MGMT and DNA repair genes and the risk of esophageal adenocarcinoma
    • Doecke J., Zhao Z.Z., Pandeya N., et al. Polymorphisms in MGMT and DNA repair genes and the risk of esophageal adenocarcinoma. Int J Cancer 2008, 123:174-180.
    • (2008) Int J Cancer , vol.123 , pp. 174-180
    • Doecke, J.1    Zhao, Z.Z.2    Pandeya, N.3
  • 31
    • 45349096041 scopus 로고    scopus 로고
    • American Cancer Society, American Cancer Society, Atlanta
    • Cancer facts and figures 2008, 4-17. American Cancer Society, American Cancer Society, Atlanta.
    • (2008) Cancer facts and figures , pp. 4-17
  • 32
    • 0001852007 scopus 로고
    • The two histologic main types of gastric carcinoma
    • Lauren T. The two histologic main types of gastric carcinoma. Acta Pathol Microbiol Scand 1965, 64:34.
    • (1965) Acta Pathol Microbiol Scand , vol.64 , pp. 34
    • Lauren, T.1
  • 33
    • 0014419134 scopus 로고
    • Histologic types of gastric carcinoma in high- and low-risk areas
    • Munoz N., Correa P., Cuello C., et al. Histologic types of gastric carcinoma in high- and low-risk areas. Int J Cancer 1968, 3:809-818.
    • (1968) Int J Cancer , vol.3 , pp. 809-818
    • Munoz, N.1    Correa, P.2    Cuello, C.3
  • 34
    • 0029850770 scopus 로고    scopus 로고
    • Family history-related risk of gastric cancer in Japan: a hospital-based case-control study
    • Nagase H., Ogino K., Yoshida I., et al. Family history-related risk of gastric cancer in Japan: a hospital-based case-control study. Jpn J Cancer Res 1996, 87(10):1025-1028.
    • (1996) Jpn J Cancer Res , vol.87 , Issue.10 , pp. 1025-1028
    • Nagase, H.1    Ogino, K.2    Yoshida, I.3
  • 36
    • 0025104110 scopus 로고
    • Familial occurrence of gastric cancer in the 2-year experience of a population-based registry
    • Zanghieri G., Di Gregorio C., Sacchetti C., et al. Familial occurrence of gastric cancer in the 2-year experience of a population-based registry. Cancer 1990, 66:2047-2051.
    • (1990) Cancer , vol.66 , pp. 2047-2051
    • Zanghieri, G.1    Di Gregorio, C.2    Sacchetti, C.3
  • 37
    • 0034644185 scopus 로고    scopus 로고
    • Environmental and heritable factors in the causation of cancer
    • Lichtenstein P., Holm N.V., Verkasalo P.K., et al. Environmental and heritable factors in the causation of cancer. N Engl J Med 2000, 343(2):78-85.
    • (2000) N Engl J Med , vol.343 , Issue.2 , pp. 78-85
    • Lichtenstein, P.1    Holm, N.V.2    Verkasalo, P.K.3
  • 38
    • 0033432725 scopus 로고    scopus 로고
    • Familial gastric cancer: overview and guidelines for management
    • Caldas C., Carniero F., Lynch H.T., et al. Familial gastric cancer: overview and guidelines for management. J Med Genet 1999, 36:873-880.
    • (1999) J Med Genet , vol.36 , pp. 873-880
    • Caldas, C.1    Carniero, F.2    Lynch, H.T.3
  • 39
    • 0032568370 scopus 로고    scopus 로고
    • E-cadherin germline mutations in familial gastric cancer
    • Guilford P., Hopkins J., Harraway J., et al. E-cadherin germline mutations in familial gastric cancer. Nature 1998, 392:402-405.
    • (1998) Nature , vol.392 , pp. 402-405
    • Guilford, P.1    Hopkins, J.2    Harraway, J.3
  • 40
    • 0032865483 scopus 로고    scopus 로고
    • E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer
    • Guilford P.J., Hopkins J.B., Grady W.M., et al. E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer. Hum Mutat 1999, 14(3):249-255.
    • (1999) Hum Mutat , vol.14 , Issue.3 , pp. 249-255
    • Guilford, P.J.1    Hopkins, J.B.2    Grady, W.M.3
  • 41
    • 64549109715 scopus 로고    scopus 로고
    • Germline CDH1 deletions in hereditary diffuse gastric cancer families
    • Oliveira C., Senz J., Kaurah P., et al. Germline CDH1 deletions in hereditary diffuse gastric cancer families. Hum Mol Genet 2009, 18(9):1545-1555.
    • (2009) Hum Mol Genet , vol.18 , Issue.9 , pp. 1545-1555
    • Oliveira, C.1    Senz, J.2    Kaurah, P.3
  • 42
    • 34249989159 scopus 로고    scopus 로고
    • Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer
    • Kaurah P., MacMillan A., Boyd N., et al. Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer. JAMA 2007, 297(21):2360-2372.
    • (2007) JAMA , vol.297 , Issue.21 , pp. 2360-2372
    • Kaurah, P.1    MacMillan, A.2    Boyd, N.3
  • 43
    • 77950533734 scopus 로고    scopus 로고
    • Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer
    • Pinheiro H., Bordeira-Carrico R., Seixas S., et al. Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer. Hum Mol Genet 2010, 19(5):943-952.
    • (2010) Hum Mol Genet , vol.19 , Issue.5 , pp. 943-952
    • Pinheiro, H.1    Bordeira-Carrico, R.2    Seixas, S.3
  • 44
    • 0035927967 scopus 로고    scopus 로고
    • Early gastric cancer in young, asymptomatic carriers of germ-line E-cadherin mutations
    • Huntsman D.G., Carneiro F., Lewis F.R., et al. Early gastric cancer in young, asymptomatic carriers of germ-line E-cadherin mutations. N Engl J Med 2001, 344(25):1904-1909.
    • (2001) N Engl J Med , vol.344 , Issue.25 , pp. 1904-1909
    • Huntsman, D.G.1    Carneiro, F.2    Lewis, F.R.3
  • 45
    • 19644385515 scopus 로고    scopus 로고
    • Gastric cancer: new genetic developments
    • Lynch H.T., Grady W., Suriano G., et al. Gastric cancer: new genetic developments. J Surg Oncol 2005, 90(3):114-133.
    • (2005) J Surg Oncol , vol.90 , Issue.3 , pp. 114-133
    • Lynch, H.T.1    Grady, W.2    Suriano, G.3
  • 46
    • 0024243893 scopus 로고
    • Hereditary nonpolyposis colorectal cancer-Lynch syndromes I and II
    • Lynch H.T., Lanspa S.J., Boman B.M., et al. Hereditary nonpolyposis colorectal cancer-Lynch syndromes I and II. Gastroenterol Clin North Am 1988, 17(4):679-712.
    • (1988) Gastroenterol Clin North Am , vol.17 , Issue.4 , pp. 679-712
    • Lynch, H.T.1    Lanspa, S.J.2    Boman, B.M.3
  • 47
    • 67650924286 scopus 로고    scopus 로고
    • Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications
    • Lynch H.T., Lynch P.M., Lanspa S.J., et al. Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications. Clin Genet 2009, 76(1):1-18.
    • (2009) Clin Genet , vol.76 , Issue.1 , pp. 1-18
    • Lynch, H.T.1    Lynch, P.M.2    Lanspa, S.J.3
  • 48
    • 0030659081 scopus 로고    scopus 로고
    • Features of gastric cancer in hereditary non-polyposis colorectal cancer syndrome
    • Aarnio M., Salovaara R., Aaltonen L., et al. Features of gastric cancer in hereditary non-polyposis colorectal cancer syndrome. Int J Cancer 1997, 74(5):551-555.
    • (1997) Int J Cancer , vol.74 , Issue.5 , pp. 551-555
    • Aarnio, M.1    Salovaara, R.2    Aaltonen, L.3
  • 49
    • 0029862873 scopus 로고    scopus 로고
    • Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis
    • Vasen H.F., Wijnen J.T., Menko F.H., et al. Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis. Gastroenterology 1996, 110(4):1020-1027.
    • (1996) Gastroenterology , vol.110 , Issue.4 , pp. 1020-1027
    • Vasen, H.F.1    Wijnen, J.T.2    Menko, F.H.3
  • 50
    • 0023223410 scopus 로고
    • Localization of the gene for familial adenomatous polyposis on chromosome 5
    • Bodmer W.F., Bailey C.J., Bodmer J., et al. Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature 1987, 328:614-616.
    • (1987) Nature , vol.328 , pp. 614-616
    • Bodmer, W.F.1    Bailey, C.J.2    Bodmer, J.3
  • 51
    • 0025938038 scopus 로고
    • Identification and characterization of the familial adenomatous polyposis gene
    • Groden J., Thliveris A., Samowitz W., et al. Identification and characterization of the familial adenomatous polyposis gene. Cell 1991, 66:589-600.
    • (1991) Cell , vol.66 , pp. 589-600
    • Groden, J.1    Thliveris, A.2    Samowitz, W.3
  • 52
    • 0027401607 scopus 로고
    • The multistep nature of cancer
    • Vogelstein B., Kinzler K.W. The multistep nature of cancer. Trends Genet 1993, 9:138-141.
    • (1993) Trends Genet , vol.9 , pp. 138-141
    • Vogelstein, B.1    Kinzler, K.W.2
  • 53
    • 33749035975 scopus 로고    scopus 로고
    • Surveillance and management of upper gastrointestinal disease in familial adenomatous polyposis
    • Gallagher M.C., Phillips R.K., Bulow S. Surveillance and management of upper gastrointestinal disease in familial adenomatous polyposis. Fam Cancer 2006, 5:263-273.
    • (2006) Fam Cancer , vol.5 , pp. 263-273
    • Gallagher, M.C.1    Phillips, R.K.2    Bulow, S.3
  • 54
    • 0026537747 scopus 로고
    • The risk of upper gastrointestinal cancer in familial adenomatous polyposis
    • Offerhaus G.J., Giardiello F.M., Krush A.J., et al. The risk of upper gastrointestinal cancer in familial adenomatous polyposis. Gastroenterology 1992, 102:1980-1982.
    • (1992) Gastroenterology , vol.102 , pp. 1980-1982
    • Offerhaus, G.J.1    Giardiello, F.M.2    Krush, A.J.3
  • 55
    • 3843061612 scopus 로고    scopus 로고
    • E-cadherin, CDH1, and p53 rather than SMAD4 and Caspase-10 germline mutations contribute to genetic predisposition in Portuguese gastric cancer patients
    • Oliveira C., Ferreira P., Nabais S., et al. E-cadherin, CDH1, and p53 rather than SMAD4 and Caspase-10 germline mutations contribute to genetic predisposition in Portuguese gastric cancer patients. Eur J Cancer 2004, 40:1897-1903.
    • (2004) Eur J Cancer , vol.40 , pp. 1897-1903
    • Oliveira, C.1    Ferreira, P.2    Nabais, S.3
  • 56
    • 0036370334 scopus 로고    scopus 로고
    • Helicobacter pylori and gastrointestinal tract adenocarcinomas
    • Peek R.M., Blaser M.J. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat Rev Cancer 2002, 2:28-37.
    • (2002) Nat Rev Cancer , vol.2 , pp. 28-37
    • Peek, R.M.1    Blaser, M.J.2
  • 57
    • 0035856021 scopus 로고    scopus 로고
    • Helicobacter pylori infection and the development of gastric cancer
    • Uemura N., Okamoto S., Yamamoto S., et al. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 2001, 345(11):784-789.
    • (2001) N Engl J Med , vol.345 , Issue.11 , pp. 784-789
    • Uemura, N.1    Okamoto, S.2    Yamamoto, S.3
  • 58
    • 0028694306 scopus 로고
    • Schistosomes, liver flukes and Helicobacter pylori. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon, 7-14 June 1994
    • Schistosomes, liver flukes and Helicobacter pylori. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon, 7-14 June 1994. IARC Monogr Eval Carcinog Risks Hum 1994, 61:1-241.
    • (1994) IARC Monogr Eval Carcinog Risks Hum , vol.61 , pp. 1-241
  • 59
    • 0034063731 scopus 로고    scopus 로고
    • Seroprevalence and ethnic differences in Helicobacter pylori infection among adults in the United States
    • Everhart J.E., Kruszon-Moron D., Perez-Perez G.I., et al. Seroprevalence and ethnic differences in Helicobacter pylori infection among adults in the United States. J Infect Dis 2000, 181:1359-1363.
    • (2000) J Infect Dis , vol.181 , pp. 1359-1363
    • Everhart, J.E.1    Kruszon-Moron, D.2    Perez-Perez, G.I.3
  • 61
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello C.A. Biologic basis for interleukin-1 in disease. Blood 1996, 87(6):2095-2147.
    • (1996) Blood , vol.87 , Issue.6 , pp. 2095-2147
    • Dinarello, C.A.1
  • 62
    • 0030481288 scopus 로고    scopus 로고
    • Helicobacter pylori infection enhances mucosal interleukin-1 beta, interleukin-6, and the soluble receptor of interleukin-2
    • Basso D., Scrigner M., Toma A., et al. Helicobacter pylori infection enhances mucosal interleukin-1 beta, interleukin-6, and the soluble receptor of interleukin-2. Int J Clin Lab Res 1996, 26:207-210.
    • (1996) Int J Clin Lab Res , vol.26 , pp. 207-210
    • Basso, D.1    Scrigner, M.2    Toma, A.3
  • 63
    • 0034704880 scopus 로고    scopus 로고
    • Interleukin-1 polymorphisms associated with increased risk of gastric cancer
    • El Omar E.M., Carrington M., Chow W.H., et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 2000, 404:398-402.
    • (2000) Nature , vol.404 , pp. 398-402
    • El Omar, E.M.1    Carrington, M.2    Chow, W.H.3
  • 64
    • 0037146297 scopus 로고    scopus 로고
    • Helicobacter pylori and interleukin-1 genotyping: an opportunity to identify high-risk individuals for gastric adenocarcinoma
    • Figueiredo C., Machado J.C., Pharoah P., et al. Helicobacter pylori and interleukin-1 genotyping: an opportunity to identify high-risk individuals for gastric adenocarcinoma. J Natl Cancer Inst 2002, 94(22):1680-1687.
    • (2002) J Natl Cancer Inst , vol.94 , Issue.22 , pp. 1680-1687
    • Figueiredo, C.1    Machado, J.C.2    Pharoah, P.3
  • 65
    • 33846560618 scopus 로고    scopus 로고
    • Association between interleukin-1 gene populations and Helicobacter pylori infection in gastric carcinogenesis in a Chinese population
    • Li C., Xia H.H., Xie W., et al. Association between interleukin-1 gene populations and Helicobacter pylori infection in gastric carcinogenesis in a Chinese population. J Gastroenterol Hepatol 2007, 22(2):234-239.
    • (2007) J Gastroenterol Hepatol , vol.22 , Issue.2 , pp. 234-239
    • Li, C.1    Xia, H.H.2    Xie, W.3
  • 66
    • 28644442435 scopus 로고    scopus 로고
    • Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan
    • Taguchi A., Ohmiya N., Shirai K., et al. Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan. Cancer Epidemiol Biomarkers Prev 2005, 15:2487-2493.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 2487-2493
    • Taguchi, A.1    Ohmiya, N.2    Shirai, K.3
  • 67
    • 0032030668 scopus 로고    scopus 로고
    • Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-B in gastric epithelial cells
    • Sharma S.A., Tummuru M.K., Blaser M.J., et al. Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-B in gastric epithelial cells. J Immunol 1998, 160:2401-2407.
    • (1998) J Immunol , vol.160 , pp. 2401-2407
    • Sharma, S.A.1    Tummuru, M.K.2    Blaser, M.J.3
  • 68
    • 0036546501 scopus 로고    scopus 로고
    • NF-kB in cancer: from innocent bystander to major culprit
    • Karin M., Cao Y., Greten F.R., et al. NF-kB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002, 2:301-310.
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3
  • 69
    • 0035542950 scopus 로고    scopus 로고
    • Nuclear factor-kB p65 (RelA) transcription factor is constitutively activated in human gastric carcinoma tissue
    • Sasaki N., Morisaki T., Hashizume K., et al. Nuclear factor-kB p65 (RelA) transcription factor is constitutively activated in human gastric carcinoma tissue. Clin Cancer Res 2001, 7:4136-4142.
    • (2001) Clin Cancer Res , vol.7 , pp. 4136-4142
    • Sasaki, N.1    Morisaki, T.2    Hashizume, K.3
  • 70
    • 25144473975 scopus 로고    scopus 로고
    • The -251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featuring diffuse-type histopathology in Chinese population
    • Lee W.P., Tai D.I., Lan K.H., et al. The -251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featuring diffuse-type histopathology in Chinese population. Clin Cancer Res 2005, 11(18):6431-6441.
    • (2005) Clin Cancer Res , vol.11 , Issue.18 , pp. 6431-6441
    • Lee, W.P.1    Tai, D.I.2    Lan, K.H.3
  • 71
    • 54749097888 scopus 로고    scopus 로고
    • A systematic review of meta-analyses on gene polymorphisms and gastric cancer risk
    • Gianfagna F., De Feo E., Van Duijn C.M., et al. A systematic review of meta-analyses on gene polymorphisms and gastric cancer risk. Curr Genomics 2008, 9:361-374.
    • (2008) Curr Genomics , vol.9 , pp. 361-374
    • Gianfagna, F.1    De Feo, E.2    Van Duijn, C.M.3
  • 73
    • 0035409832 scopus 로고    scopus 로고
    • Familial pancreatic cancer
    • Klein A.P., Hruban R.H., Brune K.A., et al. Familial pancreatic cancer. Cancer J 2001, 7(4):266-273.
    • (2001) Cancer J , vol.7 , Issue.4 , pp. 266-273
    • Klein, A.P.1    Hruban, R.H.2    Brune, K.A.3
  • 74
    • 0034046621 scopus 로고    scopus 로고
    • Hereditary pancreatic adenocarcinoma. A clinical perspective
    • Brand R.E., Lynch H.T. Hereditary pancreatic adenocarcinoma. A clinical perspective. Med Clin North Am 2000, 84(3):665-675.
    • (2000) Med Clin North Am , vol.84 , Issue.3 , pp. 665-675
    • Brand, R.E.1    Lynch, H.T.2
  • 75
  • 76
    • 0033382686 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 and breast cancer incidence: a review
    • Bishop D.T. BRCA1 and BRCA2 and breast cancer incidence: a review. Ann Oncol 1999, 10(Suppl 6):113-119.
    • (1999) Ann Oncol , vol.10 , Issue.SUPPL 6 , pp. 113-119
    • Bishop, D.T.1
  • 77
    • 0033523268 scopus 로고    scopus 로고
    • Cancer risks in BRCA2 mutation carriers. The Breast Cancer Linkage Consortium
    • Cancer risks in BRCA2 mutation carriers. The Breast Cancer Linkage Consortium. J Natl Cancer Inst 1999, 91(15):1310-1316.
    • (1999) J Natl Cancer Inst , vol.91 , Issue.15 , pp. 1310-1316
  • 78
    • 0036644884 scopus 로고    scopus 로고
    • Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17%
    • Murphy K.M., Brune K.A., Griffin C., et al. Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17%. Cancer Res 2002, 62(13):3789-3793.
    • (2002) Cancer Res , vol.62 , Issue.13 , pp. 3789-3793
    • Murphy, K.M.1    Brune, K.A.2    Griffin, C.3
  • 79
    • 15744394400 scopus 로고    scopus 로고
    • BRCA1 and pancreatic cancer: pedigree findings and their causal relationships
    • Lynch H.T., Detres C.A., Snyder C.L., et al. BRCA1 and pancreatic cancer: pedigree findings and their causal relationships. Cancer Genet Cytogenet 2005, 158(2):119-125.
    • (2005) Cancer Genet Cytogenet , vol.158 , Issue.2 , pp. 119-125
    • Lynch, H.T.1    Detres, C.A.2    Snyder, C.L.3
  • 80
    • 0037130887 scopus 로고    scopus 로고
    • Breast Cancer Linkage Consortium. Cancer incidence in BRCA1 mutation carriers
    • Thompson D., Easton D.F. Breast Cancer Linkage Consortium. Cancer incidence in BRCA1 mutation carriers. J Natl Cancer Inst 2002, 94(18):1358-1365.
    • (2002) J Natl Cancer Inst , vol.94 , Issue.18 , pp. 1358-1365
    • Thompson, D.1    Easton, D.F.2
  • 81
    • 0022391090 scopus 로고
    • Pancreatic carcinoma and hereditary nonpolyposis colorectal cancer: a family study
    • Lynch H.T., Voorhees G.J., Lanspa S.J., et al. Pancreatic carcinoma and hereditary nonpolyposis colorectal cancer: a family study. Br J Cancer 1985, 52(2):271-273.
    • (1985) Br J Cancer , vol.52 , Issue.2 , pp. 271-273
    • Lynch, H.T.1    Voorhees, G.J.2    Lanspa, S.J.3
  • 82
    • 10744233937 scopus 로고    scopus 로고
    • Revised Bethesda guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability
    • Umar A., Boland C.R., Terdiman J.P., et al. Revised Bethesda guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst 2004, 96(4):261-268.
    • (2004) J Natl Cancer Inst , vol.96 , Issue.4 , pp. 261-268
    • Umar, A.1    Boland, C.R.2    Terdiman, J.P.3
  • 83
    • 45749151120 scopus 로고    scopus 로고
    • Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC)
    • Geary J., Sasieni P., Houlston R., et al. Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC). Fam Cancer 2008, 7(2):163-172.
    • (2008) Fam Cancer , vol.7 , Issue.2 , pp. 163-172
    • Geary, J.1    Sasieni, P.2    Houlston, R.3
  • 84
    • 0033847858 scopus 로고    scopus 로고
    • Genetic, immunohistochemical, and clinical features of medullary carcinoma of the pancreas: a newly described and characterized entity
    • Wilentz R.E., Goggins M., Redston M., et al. Genetic, immunohistochemical, and clinical features of medullary carcinoma of the pancreas: a newly described and characterized entity. Am J Pathol 2000, 156(5):1641-1651.
    • (2000) Am J Pathol , vol.156 , Issue.5 , pp. 1641-1651
    • Wilentz, R.E.1    Goggins, M.2    Redston, M.3
  • 85
    • 33750083369 scopus 로고    scopus 로고
    • Medullary carcinoma of the pancreas in a man with hereditary nonpolyposis colorectal cancer due to a mutation of the MSH2 mismatch repair gene
    • Banville N., Geraghty R., Fox E., et al. Medullary carcinoma of the pancreas in a man with hereditary nonpolyposis colorectal cancer due to a mutation of the MSH2 mismatch repair gene. Hum Pathol 2006, 37(11):1498-1502.
    • (2006) Hum Pathol , vol.37 , Issue.11 , pp. 1498-1502
    • Banville, N.1    Geraghty, R.2    Fox, E.3
  • 86
    • 70449521011 scopus 로고    scopus 로고
    • Germline MLH1 and MSH2 mutations in Italian pancreatic cancer patients with suspected Lynch syndrome
    • Gargiulo S., Torrini M., Ollila S., et al. Germline MLH1 and MSH2 mutations in Italian pancreatic cancer patients with suspected Lynch syndrome. Fam Cancer 2009, 8(4):547-553.
    • (2009) Fam Cancer , vol.8 , Issue.4 , pp. 547-553
    • Gargiulo, S.1    Torrini, M.2    Ollila, S.3
  • 87
    • 70350733425 scopus 로고    scopus 로고
    • Risk of pancreatic cancer in families with Lynch syndrome
    • Kastrinos F., Mukherjee B., Tayob N., et al. Risk of pancreatic cancer in families with Lynch syndrome. JAMA 2009, 302(16):1790-1795.
    • (2009) JAMA , vol.302 , Issue.16 , pp. 1790-1795
    • Kastrinos, F.1    Mukherjee, B.2    Tayob, N.3
  • 88
    • 0035300547 scopus 로고    scopus 로고
    • Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability
    • Yamamoto H., Itoh F., Nakamura H., et al. Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability. Cancer Res 2001, 61(7):3139-3144.
    • (2001) Cancer Res , vol.61 , Issue.7 , pp. 3139-3144
    • Yamamoto, H.1    Itoh, F.2    Nakamura, H.3
  • 89
    • 4544274825 scopus 로고    scopus 로고
    • Familial melanoma, pancreatic cancer and germline CDKN2A mutations
    • Goldstein A.M. Familial melanoma, pancreatic cancer and germline CDKN2A mutations. Hum Mutat 2004, 23(6):630.
    • (2004) Hum Mutat , vol.23 , Issue.6 , pp. 630
    • Goldstein, A.M.1
  • 90
    • 0030584195 scopus 로고    scopus 로고
    • Familial melanoma and pancreatic cancer
    • Bergman W., Gruis N. Familial melanoma and pancreatic cancer. N Engl J Med 1996, 334(7):471-472.
    • (1996) N Engl J Med , vol.334 , Issue.7 , pp. 471-472
    • Bergman, W.1    Gruis, N.2
  • 91
    • 0025284650 scopus 로고
    • Systemic cancer and the FAMMM syndrome
    • Bergman W., Watson P., de Jong J., et al. Systemic cancer and the FAMMM syndrome. Br J Cancer 1990, 61(6):932-936.
    • (1990) Br J Cancer , vol.61 , Issue.6 , pp. 932-936
    • Bergman, W.1    Watson, P.2    de Jong, J.3
  • 92
    • 0034596343 scopus 로고    scopus 로고
    • High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families
    • Borg A., Sandberg T., Nilsson K., et al. High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families. J Natl Cancer Inst 2000, 92(15):1260-1266.
    • (2000) J Natl Cancer Inst , vol.92 , Issue.15 , pp. 1260-1266
    • Borg, A.1    Sandberg, T.2    Nilsson, K.3
  • 93
    • 0033836334 scopus 로고    scopus 로고
    • Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden)
    • Vasen H.F., Gruis N.A., Frants R.R., et al. Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden). Int J Cancer 2000, 87(6):809-811.
    • (2000) Int J Cancer , vol.87 , Issue.6 , pp. 809-811
    • Vasen, H.F.1    Gruis, N.A.2    Frants, R.R.3
  • 94
    • 0036143702 scopus 로고    scopus 로고
    • Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: the familial atypical mole melanoma-pancreatic carcinoma syndrome
    • Lynch H.T., Brand R.E., Hogg D., et al. Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: the familial atypical mole melanoma-pancreatic carcinoma syndrome. Cancer 2002, 94(1):84-96.
    • (2002) Cancer , vol.94 , Issue.1 , pp. 84-96
    • Lynch, H.T.1    Brand, R.E.2    Hogg, D.3
  • 95
    • 33645838599 scopus 로고    scopus 로고
    • Peutz-Jeghers syndrome and management recommendations
    • Giardiello F.M., Trimbath J.D. Peutz-Jeghers syndrome and management recommendations. Clin Gastroenterol Hepatol 2006, 4(4):408-415.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , Issue.4 , pp. 408-415
    • Giardiello, F.M.1    Trimbath, J.D.2
  • 96
    • 0023192463 scopus 로고
    • Increased risk of cancer in the Peutz-Jeghers syndrome
    • Giardiello F.M., Welsh S.B., Hamilton S.R., et al. Increased risk of cancer in the Peutz-Jeghers syndrome. N Engl J Med 1987, 316(24):1511-1514.
    • (1987) N Engl J Med , vol.316 , Issue.24 , pp. 1511-1514
    • Giardiello, F.M.1    Welsh, S.B.2    Hamilton, S.R.3
  • 97
    • 33744782567 scopus 로고    scopus 로고
    • Frequency and spectrum of cancers in the Peutz-Jeghers syndrome
    • Hearle N., Schumacher V., Menko F.H., et al. Frequency and spectrum of cancers in the Peutz-Jeghers syndrome. Clin Cancer Res 2006, 12(10):3209-3215.
    • (2006) Clin Cancer Res , vol.12 , Issue.10 , pp. 3209-3215
    • Hearle, N.1    Schumacher, V.2    Menko, F.H.3
  • 98
    • 0034464147 scopus 로고    scopus 로고
    • Very high risk of cancer in familial Peutz-Jeghers syndrome
    • Giardiello F.M., Brensinger J.D., Tersmette A.C., et al. Very high risk of cancer in familial Peutz-Jeghers syndrome. Gastroenterology 2000, 119(6):1447-1453.
    • (2000) Gastroenterology , vol.119 , Issue.6 , pp. 1447-1453
    • Giardiello, F.M.1    Brensinger, J.D.2    Tersmette, A.C.3
  • 99
    • 2942527434 scopus 로고    scopus 로고
    • Relative frequency and morphology of cancers in STK11 mutation carriers
    • Lim W., Olschwang S., Keller J.J., et al. Relative frequency and morphology of cancers in STK11 mutation carriers. Gastroenterology 2004, 126(7):1788-1794.
    • (2004) Gastroenterology , vol.126 , Issue.7 , pp. 1788-1794
    • Lim, W.1    Olschwang, S.2    Keller, J.J.3
  • 100
    • 0027429364 scopus 로고
    • Increased risk of thyroid and pancreatic carcinoma in familial adenomatous polyposis
    • Giardiello F.M., Offerhaus G.J., Lee D.H., et al. Increased risk of thyroid and pancreatic carcinoma in familial adenomatous polyposis. Gut 1993, 34(10):1394-1396.
    • (1993) Gut , vol.34 , Issue.10 , pp. 1394-1396
    • Giardiello, F.M.1    Offerhaus, G.J.2    Lee, D.H.3
  • 101
    • 50049124155 scopus 로고    scopus 로고
    • Extra-intestinal manifestations of familial adenomatous polyposis
    • Groen E.J., Roos A., Muntinghe F.L., et al. Extra-intestinal manifestations of familial adenomatous polyposis. Ann Surg Oncol 2008, 15(9):2439-2450.
    • (2008) Ann Surg Oncol , vol.15 , Issue.9 , pp. 2439-2450
    • Groen, E.J.1    Roos, A.2    Muntinghe, F.L.3
  • 102
    • 0026470030 scopus 로고
    • Frequent somatic mutations of the APC gene in human pancreatic cancer
    • Horii A., Nakatsuru S., Miyoshi Y., et al. Frequent somatic mutations of the APC gene in human pancreatic cancer. Cancer Res 1992, 52(23):6696-6698.
    • (1992) Cancer Res , vol.52 , Issue.23 , pp. 6696-6698
    • Horii, A.1    Nakatsuru, S.2    Miyoshi, Y.3
  • 103
    • 27744511341 scopus 로고    scopus 로고
    • High-grade pancreatic intraepithelial neoplasia in a patient with familial adenomatous polyposis
    • Gupta C., Mazzara P.F. High-grade pancreatic intraepithelial neoplasia in a patient with familial adenomatous polyposis. Arch Pathol Lab Med 2005, 129(11):1398-1400.
    • (2005) Arch Pathol Lab Med , vol.129 , Issue.11 , pp. 1398-1400
    • Gupta, C.1    Mazzara, P.F.2
  • 104
    • 0030975440 scopus 로고    scopus 로고
    • Hereditary pancreatitis and the risk of pancreatic cancer. International Hereditary Pancreatitis Study Group
    • Lowenfels A.B., Maisonneuve P., DiMagno E.P., et al. Hereditary pancreatitis and the risk of pancreatic cancer. International Hereditary Pancreatitis Study Group. J Natl Cancer Inst 1997, 89(6):442-446.
    • (1997) J Natl Cancer Inst , vol.89 , Issue.6 , pp. 442-446
    • Lowenfels, A.B.1    Maisonneuve, P.2    DiMagno, E.P.3
  • 105
    • 10144246566 scopus 로고    scopus 로고
    • Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene
    • Whitcomb D.C., Gorry M.C., Preston R.A., et al. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet 1996, 14(2):141-145.
    • (1996) Nat Genet , vol.14 , Issue.2 , pp. 141-145
    • Whitcomb, D.C.1    Gorry, M.C.2    Preston, R.A.3
  • 106
    • 0017781597 scopus 로고
    • Pancreatic cancer in father and son
    • Reimer R.R., Fraumeni J.F., Ozols R.F., et al. Pancreatic cancer in father and son. Lancet 1977, 1(8017):911.
    • (1977) Lancet , vol.1 , Issue.8017 , pp. 911
    • Reimer, R.R.1    Fraumeni, J.F.2    Ozols, R.F.3
  • 107
    • 0023233894 scopus 로고
    • Familial pancreatic adenocarcinoma in three generations. A case report and a review of the literature
    • Ehrenthal D., Haeger L., Griffin T., et al. Familial pancreatic adenocarcinoma in three generations. A case report and a review of the literature. Cancer 1987, 59(9):1661-1664.
    • (1987) Cancer , vol.59 , Issue.9 , pp. 1661-1664
    • Ehrenthal, D.1    Haeger, L.2    Griffin, T.3
  • 108
    • 0026324378 scopus 로고
    • Reported family aggregation of pancreatic cancer within a population-based case-control study in the Francophone community in Montreal, Canada
    • Ghadirian P., Boyle P., Simard A., et al. Reported family aggregation of pancreatic cancer within a population-based case-control study in the Francophone community in Montreal, Canada. Int J Pancreatol 1991, 10(3-4):183-196.
    • (1991) Int J Pancreatol , vol.10 , Issue.3-4 , pp. 183-196
    • Ghadirian, P.1    Boyle, P.2    Simard, A.3
  • 109
    • 0025055664 scopus 로고
    • Familial pancreatic cancer: clinicopathologic study of 18 nuclear families
    • Lynch H.T., Fitzsimmons M.L., Smyrk T.C., et al. Familial pancreatic cancer: clinicopathologic study of 18 nuclear families. Am J Gastroenterol 1990, 85(1):54-60.
    • (1990) Am J Gastroenterol , vol.85 , Issue.1 , pp. 54-60
    • Lynch, H.T.1    Fitzsimmons, M.L.2    Smyrk, T.C.3
  • 110
    • 0032807116 scopus 로고    scopus 로고
    • Familial pancreatic cancer
    • Hruban R.H., Petersen G.M., Goggins M., et al. Familial pancreatic cancer. Ann Oncol 1999, 10(Suppl 4):69-73.
    • (1999) Ann Oncol , vol.10 , Issue.SUPPL 4 , pp. 69-73
    • Hruban, R.H.1    Petersen, G.M.2    Goggins, M.3
  • 111
    • 0034650411 scopus 로고    scopus 로고
    • Inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, BRCA1, and BRCA2 mutations
    • Lal G., Liu G., Schmocker B., et al. Inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, BRCA1, and BRCA2 mutations. Cancer Res 2000, 60(2):409-416.
    • (2000) Cancer Res , vol.60 , Issue.2 , pp. 409-416
    • Lal, G.1    Liu, G.2    Schmocker, B.3
  • 112
    • 0036668721 scopus 로고    scopus 로고
    • Evidence for a major gene influencing risk of pancreatic cancer
    • Klein A.P., Beaty T.H., Bailey-Wilson J.E., et al. Evidence for a major gene influencing risk of pancreatic cancer. Genet Epidemiol 2002, 23(2):133-149.
    • (2002) Genet Epidemiol , vol.23 , Issue.2 , pp. 133-149
    • Klein, A.P.1    Beaty, T.H.2    Bailey-Wilson, J.E.3
  • 113
    • 0034901004 scopus 로고    scopus 로고
    • Increased risk of incident pancreatic cancer among first-degree relatives of patients with familial pancreatic cancer
    • Tersmette A.C., Petersen G.M., Offerhaus G.J., et al. Increased risk of incident pancreatic cancer among first-degree relatives of patients with familial pancreatic cancer. Clin Cancer Res 2001, 7(3):738-744.
    • (2001) Clin Cancer Res , vol.7 , Issue.3 , pp. 738-744
    • Tersmette, A.C.1    Petersen, G.M.2    Offerhaus, G.J.3
  • 114
    • 11144353646 scopus 로고    scopus 로고
    • Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds
    • Klein A.P., Brune K.A., Petersen G.M., et al. Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds. Cancer Res 2004, 64(7):2634-2638.
    • (2004) Cancer Res , vol.64 , Issue.7 , pp. 2634-2638
    • Klein, A.P.1    Brune, K.A.2    Petersen, G.M.3
  • 115
    • 33845885517 scopus 로고    scopus 로고
    • Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism
    • Pogue-Geile K.L., Chen R., Bonner M.P., et al. Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism. PLoS Med 2006, 3(12):e516.
    • (2006) PLoS Med , vol.3 , Issue.12
    • Pogue-Geile, K.L.1    Chen, R.2    Bonner, M.P.3
  • 116
    • 34548270466 scopus 로고    scopus 로고
    • Linkage analysis of chromosome 4 in families with familial pancreatic cancer
    • Klein A.P., de Andrade M., Hruban R.H., et al. Linkage analysis of chromosome 4 in families with familial pancreatic cancer. Cancer Biol Ther 2007, 6(3):320-323.
    • (2007) Cancer Biol Ther , vol.6 , Issue.3 , pp. 320-323
    • Klein, A.P.1    de Andrade, M.2    Hruban, R.H.3
  • 117
    • 34247470247 scopus 로고    scopus 로고
    • Palladin mutation causes familial pancreatic cancer: absence in European families
    • Slater E., Amrillaeva V., Fendrich V., et al. Palladin mutation causes familial pancreatic cancer: absence in European families. PLoS Med 2007, 4(4):e164.
    • (2007) PLoS Med , vol.4 , Issue.4
    • Slater, E.1    Amrillaeva, V.2    Fendrich, V.3
  • 118
    • 34248185509 scopus 로고    scopus 로고
    • The P239S palladin variant does not account for a significant fraction of hereditary or early onset pancreas cancer
    • Zogopoulos G., Rothenmund H., Eppel A., et al. The P239S palladin variant does not account for a significant fraction of hereditary or early onset pancreas cancer. Hum Genet 2007, 121(5):635-637.
    • (2007) Hum Genet , vol.121 , Issue.5 , pp. 635-637
    • Zogopoulos, G.1    Rothenmund, H.2    Eppel, A.3
  • 119
    • 66649108796 scopus 로고    scopus 로고
    • Absence of deleterious palladin mutations in patients with familial pancreatic cancer
    • Klein A.P., Borges M., Griffith M., et al. Absence of deleterious palladin mutations in patients with familial pancreatic cancer. Cancer Epidemiol Biomarkers Prev 2009, 18(4):1328-1330.
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , Issue.4 , pp. 1328-1330
    • Klein, A.P.1    Borges, M.2    Griffith, M.3
  • 120
    • 52349098983 scopus 로고    scopus 로고
    • International registries of families at high risk of pancreatic cancer
    • Greenhalf W., Malats N., Nilsson M., et al. International registries of families at high risk of pancreatic cancer. Pancreatology 2008, 8(6):558-565.
    • (2008) Pancreatology , vol.8 , Issue.6 , pp. 558-565
    • Greenhalf, W.1    Malats, N.2    Nilsson, M.3
  • 121
    • 34248204213 scopus 로고    scopus 로고
    • Precursor lesions of pancreatic cancer: molecular pathology and clinical implications
    • Singh M., Maitra A. Precursor lesions of pancreatic cancer: molecular pathology and clinical implications. Pancreatology 2007, 7(1):9-19.
    • (2007) Pancreatology , vol.7 , Issue.1 , pp. 9-19
    • Singh, M.1    Maitra, A.2
  • 122
    • 0033578479 scopus 로고    scopus 로고
    • Early diagnosis and treatment of pancreatic dysplasia in patients with a family history of pancreatic cancer
    • Brentnall T.A., Bronner M.P., Byrd D.R., et al. Early diagnosis and treatment of pancreatic dysplasia in patients with a family history of pancreatic cancer. Ann Intern Med 1999, 131(4):247-255.
    • (1999) Ann Intern Med , vol.131 , Issue.4 , pp. 247-255
    • Brentnall, T.A.1    Bronner, M.P.2    Byrd, D.R.3
  • 123
    • 3042525898 scopus 로고    scopus 로고
    • Screening for pancreatic neoplasia in high-risk individuals: an EUS-based approach
    • Canto M.I., Goggins M., Yeo C.J., et al. Screening for pancreatic neoplasia in high-risk individuals: an EUS-based approach. Clin Gastroenterol Hepatol 2004, 2(7):606-621.
    • (2004) Clin Gastroenterol Hepatol , vol.2 , Issue.7 , pp. 606-621
    • Canto, M.I.1    Goggins, M.2    Yeo, C.J.3
  • 124
    • 33744775945 scopus 로고    scopus 로고
    • Screening for early pancreatic neoplasia in high-risk individuals: a prospective controlled study
    • [quiz 665]
    • Canto M.I., Goggins M., Hruban R.H., et al. Screening for early pancreatic neoplasia in high-risk individuals: a prospective controlled study. Clin Gastroenterol Hepatol 2006, 4(6):766-781. [quiz 665].
    • (2006) Clin Gastroenterol Hepatol , vol.4 , Issue.6 , pp. 766-781
    • Canto, M.I.1    Goggins, M.2    Hruban, R.H.3
  • 125
    • 70349318044 scopus 로고    scopus 로고
    • Five years of prospective screening of high-risk individuals from families with familial pancreatic cancer
    • Langer P., Kann P.H., Fendrich V., et al. Five years of prospective screening of high-risk individuals from families with familial pancreatic cancer. Gut 2009, 58(10):1410-1418.
    • (2009) Gut , vol.58 , Issue.10 , pp. 1410-1418
    • Langer, P.1    Kann, P.H.2    Fendrich, V.3
  • 126
    • 34948870763 scopus 로고    scopus 로고
    • Advances in counselling and surveillance of patients at risk for pancreatic cancer
    • Brand R.E., Lerch M.M., Rubinstein W.S., et al. Advances in counselling and surveillance of patients at risk for pancreatic cancer. Gut 2007, 56(10):1460-1469.
    • (2007) Gut , vol.56 , Issue.10 , pp. 1460-1469
    • Brand, R.E.1    Lerch, M.M.2    Rubinstein, W.S.3
  • 127
    • 0031947592 scopus 로고    scopus 로고
    • Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal
    • Kindblom L.G., Remotti H.E., Aldenborg F., et al. Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. Am J Pathol 1998, 152(5):1259-1269.
    • (1998) Am J Pathol , vol.152 , Issue.5 , pp. 1259-1269
    • Kindblom, L.G.1    Remotti, H.E.2    Aldenborg, F.3
  • 128
    • 0020514752 scopus 로고
    • Gastric stromal tumors. Reappraisal of histogenesis
    • Mazur M.T., Clark H.B. Gastric stromal tumors. Reappraisal of histogenesis. Am J Surg Pathol 1983, 7(6):507-519.
    • (1983) Am J Surg Pathol , vol.7 , Issue.6 , pp. 507-519
    • Mazur, M.T.1    Clark, H.B.2
  • 129
    • 0036769966 scopus 로고    scopus 로고
    • Pathology and diagnostic criteria of gastrointestinal stromal tumors (GISTs): a review
    • Miettinen M., Majidi M., Lasota J. Pathology and diagnostic criteria of gastrointestinal stromal tumors (GISTs): a review. Eur J Cancer 2002, 38(Suppl 5):S39-S51.
    • (2002) Eur J Cancer , vol.38 , Issue.SUPPL 5
    • Miettinen, M.1    Majidi, M.2    Lasota, J.3
  • 130
    • 67949108222 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors I: pathology, pathobiology, primary therapy, and surgical issues
    • Reichardt P., Hogendoorn P.C., Tamborini E., et al. Gastrointestinal stromal tumors I: pathology, pathobiology, primary therapy, and surgical issues. Semin Oncol 2009, 36(4):290-301.
    • (2009) Semin Oncol , vol.36 , Issue.4 , pp. 290-301
    • Reichardt, P.1    Hogendoorn, P.C.2    Tamborini, E.3
  • 132
    • 15644363454 scopus 로고    scopus 로고
    • Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
    • Hirota S., et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998, 279(5350):577-580.
    • (1998) Science , vol.279 , Issue.5350 , pp. 577-580
    • Hirota, S.1
  • 133
    • 58749093957 scopus 로고    scopus 로고
    • Multidisciplinary treatment of gastrointestinal stromal tumors
    • x
    • Kingham T.P., DeMatteo R.P. Multidisciplinary treatment of gastrointestinal stromal tumors. Surg Clin North Am 2009, 89(1):217-233. x.
    • (2009) Surg Clin North Am , vol.89 , Issue.1 , pp. 217-233
    • Kingham, T.P.1    DeMatteo, R.P.2
  • 134
    • 62149150709 scopus 로고    scopus 로고
    • Nanoneoadjuvant therapy of gastrointestinal stromal tumor (GIST)
    • DeMatteo R.P. Nanoneoadjuvant therapy of gastrointestinal stromal tumor (GIST). Ann Surg Oncol 2009, 16(4):799-800.
    • (2009) Ann Surg Oncol , vol.16 , Issue.4 , pp. 799-800
    • DeMatteo, R.P.1
  • 135
    • 0031848146 scopus 로고    scopus 로고
    • Familial gastrointestinal stromal tumours with germline mutation of the KIT gene
    • Nishida T., Hirota S., Taniguchi M., et al. Familial gastrointestinal stromal tumours with germline mutation of the KIT gene. Nat Genet 1998, 19(4):323-324.
    • (1998) Nat Genet , vol.19 , Issue.4 , pp. 323-324
    • Nishida, T.1    Hirota, S.2    Taniguchi, M.3
  • 136
    • 60549083675 scopus 로고    scopus 로고
    • Inherited predisposition to gastrointestinal stromal tumor
    • vii
    • Agarwal R., Robson M. Inherited predisposition to gastrointestinal stromal tumor. Hematol Oncol Clin North Am 2009, 23(1):1-13. vii.
    • (2009) Hematol Oncol Clin North Am , vol.23 , Issue.1 , pp. 1-13
    • Agarwal, R.1    Robson, M.2
  • 137
    • 12144286747 scopus 로고    scopus 로고
    • Pleomorphic characteristics of a germ-line KIT mutation in a large kindred with gastrointestinal stromal tumors, hyperpigmentation, and dysphagia
    • Robson M.E., Glogowski E., Sommer G., et al. Pleomorphic characteristics of a germ-line KIT mutation in a large kindred with gastrointestinal stromal tumors, hyperpigmentation, and dysphagia. Clin Cancer Res 2004, 10(4):1250-1254.
    • (2004) Clin Cancer Res , vol.10 , Issue.4 , pp. 1250-1254
    • Robson, M.E.1    Glogowski, E.2    Sommer, G.3
  • 138
    • 37349043267 scopus 로고    scopus 로고
    • Clinical, histopathologic, molecular and therapeutic findings in a large kindred with gastrointestinal stromal tumor
    • Kleinbaum E.P., Lazar A.J., Tamborini E., et al. Clinical, histopathologic, molecular and therapeutic findings in a large kindred with gastrointestinal stromal tumor. Int J Cancer 2008, 122(3):711-718.
    • (2008) Int J Cancer , vol.122 , Issue.3 , pp. 711-718
    • Kleinbaum, E.P.1    Lazar, A.J.2    Tamborini, E.3
  • 139
    • 0025364011 scopus 로고
    • Achalasia due to diffuse esophageal eiomyomatosis and inherited as an autosomal dominant disorder. Report of a family study
    • Marshall J.B., Diaz-Arias A.A., Bochna G.S., et al. Achalasia due to diffuse esophageal eiomyomatosis and inherited as an autosomal dominant disorder. Report of a family study. Gastroenterology 1990, 98(5 pt 1):1358-1365.
    • (1990) Gastroenterology , vol.98 , Issue.5 PART 1 , pp. 1358-1365
    • Marshall, J.B.1    Diaz-Arias, A.A.2    Bochna, G.S.3
  • 140
    • 34548051808 scopus 로고    scopus 로고
    • Epithelioid gastric stromal tumours of the antrum in young females with the Carney triad: a report of three new cases with mutational analysis and comparative genomic hybridization
    • Agaimy A., Pelz A.F., Corless C.L., et al. Epithelioid gastric stromal tumours of the antrum in young females with the Carney triad: a report of three new cases with mutational analysis and comparative genomic hybridization. Oncol Rep 2007, 18(1):9-15.
    • (2007) Oncol Rep , vol.18 , Issue.1 , pp. 9-15
    • Agaimy, A.1    Pelz, A.F.2    Corless, C.L.3
  • 141
    • 33750006833 scopus 로고    scopus 로고
    • A new case of Carney triad: gastrointestinal tumours and leiomyoma of the oesophagus do not show activating mutations of KIT and platelet-derived growth factor receptor alpha
    • Knop S., Schupp M., Warderlmann E., et al. A new case of Carney triad: gastrointestinal tumours and leiomyoma of the oesophagus do not show activating mutations of KIT and platelet-derived growth factor receptor alpha. J Clin Pathol 2006, 59(10):1097-1099.
    • (2006) J Clin Pathol , vol.59 , Issue.10 , pp. 1097-1099
    • Knop, S.1    Schupp, M.2    Warderlmann, E.3
  • 142
    • 0025740382 scopus 로고
    • Gastrointestinal manifestations of type 1 neurofibromatosis (von Recklinghausen's disease)
    • Fuller C.E., Williams G.T. Gastrointestinal manifestations of type 1 neurofibromatosis (von Recklinghausen's disease). Histopathology 1991, 19(1):1-11.
    • (1991) Histopathology , vol.19 , Issue.1 , pp. 1-11
    • Fuller, C.E.1    Williams, G.T.2


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