Helicobacter pylori

Clinical Microbiology Reviews

Volumn 10, Issue 4, 1997, Pages 720-741

  Dunn, Bruce E ^a,b   Cohen, Hartley ^c   Blaser, Martin J ^d,e  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADHESIN; AMOXICILLIN; ANTIBIOTIC AGENT; BACTERIUM LIPOPOLYSACCHARIDE; BISMUTH SALICYLATE; CATALASE; CLARITHROMYCIN; CYTOTOXIN; HEAT SHOCK PROTEIN; HYALURONIDASE; INTERLEUKIN 8; METRONIDAZOLE; NITRIC OXIDE SYNTHASE; OMEPRAZOLE; PHOSPHOLIPASE; PROTON PUMP INHIBITOR; RANITIDINE BISMUTH CITRATE; REACTIVE OXYGEN METABOLITE; SIDEROPHORE; SUPEROXIDE DISMUTASE; TETRACYCLINE; THROMBOCYTE ACTIVATING FACTOR; UREASE;

ANTIBIOTIC RESISTANCE; APOPTOSIS; ARTICLE; BACTERIAL CELL WALL; BACTERIAL COLONIZATION; BACTERIAL METABOLISM; BACTERIUM ADHERENCE; BACTERIUM CULTURE; CELL ADHESION; CELL RESPIRATION; DISEASE ASSOCIATION; DISEASE TRANSMISSION; GASTRITIS; GENOME; GRAM NEGATIVE INFECTION; HELICOBACTER PYLORI; HISTOPATHOLOGY; HISTORY OF MEDICINE; HUMAN; MORPHOLOGY; NEUTROPHIL; NUTRITION; PATHOGENESIS; PLASMID; STOMACH BIOPSY; STOMACH MOTILITY; STOMACH MUCOSA;

BACTERIA (MICROORGANISMS); HELICOBACTER PYLORI; NEGIBACTERIA;

EID: 0030725576     PISSN: 08938512     EISSN: None     Source Type: Journal    
DOI: 10.1128/cmr.10.4.720-741.1997     Document Type: Article

References (355)

1. Akamatsu, T., K. Tabata, M. Hironga, H. Kawakami, and M. Uyeda. 1996. Transmission of Helicobacter pylori infection via flexible fiberoptic endoscopy. Am. J. Infect. Control 24:396-401.
2. Akopyants, N. S., D. Kersulyte, and D. E. Berg. 1995. CagII, a new multigene locus associated with virulence in Helicobacter pylori. Gut:36:A1.
3. Alemohammad, M. M., T. J. Foley, and H. Cohen. 1993. Detection of immunoglobulin G antibodies to Helicobacter pylori in urine by an enzyme immunoassay method. J. Clin. Microbiol. 31:2174-2177.
4. Andersen, L. P. and F. Espersen. 1992. Immunoglobulin G antibodies to Helicobacter pylori in patients with dyspeptic symptoms investigated by the Western immunoblot technique. J. Clin. Microbiol. 30:1743-1751.
5. Andersen, L. P., A. Norgaard, S. Holck, J. Blom, and L. Elsborg. 1996. Isolation of a "Helicobacter heilmanii"-like organism from the human stomach. Eur. J. Clin. Microbiol. Infect. Dis. 15:95-96.
6. Andrew, A., J. I. Wyatt, and M. F. Dixon. 1994. Observer variation in the assessment of chronic gastritis according to the Sydney system. Histopathology 25:317-322.
7. Andrutis, K. A., J. G. Fox, D. B. Schauer, R. P. Marini, J. C. Murphy, L. Yan, and J. V. Solnick. 1995. Inability of an isogenic urease-negative mutant strain of Helicobacter mustelae to colonize the ferret stomach. Infect. Immun. 63:3722-3725.
8. Anonymous. 1994. Schistosomes, liver flukes and Helicobacter pylori. IARC Monogr. Eval. Carcinog. Risks Hum. 61:1-241.
9. Ansorg, R., G. von Recklinghausen, and E. Heintschel von Heinegg. 1996. Susceptibility of Helicobacter pylori to simethicone and other non-antibiotic drugs. J. Antimicrob. Chemother. 37:45-52.
10. Appelmelk, B. J., I. Simoons-Smit, R. Negrini, A. P. Moran, G. O. Aspinall, J. G. Forte, T. De Vries, H. Quan, T. Verboom, J. J. Maaskant, P. Ghiara, E. J. Kuipers, E. Bloemena, T. M. Tadema, R. R. Townsend, K. Tyagarajan, J. M. Crothers, Jr., M. A. Monteiro, A. Savio, and J. De Graaff. 1996. Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity. Infect. Immun. 64:2031-2040.
11. Ascencio, F., L. A. Fransson, and T. Wadstrom. 1993. Affinity of the gastric pathogen Helicobacter pylori for the N-sulphated glycosaminoglycan hepa-ran sulphate. J. Med. Microbiol. 38:240-244.
12. Ashton-Key, M., T. C. Diss, and P. G. Isaacson. 1996. Detection of Helicobacter pylori in gastric biopsy and resection specimens. J. Clin. Pathol. 49:107-111.
13. Aspinall, G. O., and M. A. Monteiro. 1996. Lipopolysaccharides of Helicobacter pylori strains P466 and MO19: structures of the O antigen and core oligosaccharide regions. Biochemistry 35:2498-2504.
14. Aspinall, G. O., M. A. Monteiro, H. Pang, E. J. Walsh, and A. P. Moran. 1996. Lipopolysaccharide of the Helicobacter pylori type strain NCTC 11637 (ATCC 43504): structure of the O antigen chain and core oligosaccharide regions. Biochemistry 35:2489-2497.
15. Atherton, J. C., P. Cao, R. M. Peek, Jr., M. K. Tummuru, M. J. Blaser, and T. L. Cover. 1995. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. J. Biol. Chem. 270:17771-17777.
16. Atherton, J. C., M. Karita, G. Gonzalez-Valencia, M. R. Morales, K. C. Ray, R. M. Peek, G. I. Perez-Perez, T. L. Cover, and M. J. Blaser. 1996. Diversity in vacA mid-region sequence but not in signal sequence type among Helicobacter pylori strains from Japan, China, Thailand and Peru. Gut 39:A73.
17. Atherton, J. C., R. M. Peek, K. T. Tham, T. L. Cover, and M. J. Blaser. 1996. The clinical and pathological importance of heterogeneity in vacA, encoding the vacuolating cytotoxin of Helicobacter pylori. Gastroenterology 112:92-99.
18. 13C-urea breath test for Helicobacter pylori. Gut 36:337-340.
19. Austin, J. W., P. Doig, M, Stewart, and T. J. Trust. 1992. Structural comparison of urease and a GroEL analog from Helicobacter pylori. J. Bacteriol. 174:7470-7473.
20. Bagchi, D., G. Bhattacharya, and S. J. Stohs. 1996. Production of reactive oxygen species by gastric cells in association with Helicobacter pylori. Free Radical Res. 24:439-450.
21. Balk, S. C., H. S. Youn, M. H. Chung, W. K. Lee, M. J. Cho, G. H. Ko, C. K. Park, H. Kasai, aod K. H. Rhee. 1996. Increased oxidative DNA damage in Helicobacter pylori-infected human gastric mucosa. Cancer Res. 56:1279-1282.
22. Banatvala, N., K. Mayo, F. Megraud, R. Jennings, J. J. Deeks, and R. A. Feldman. 1993. The cohort effect and Helicobacter pylori. J. Infect. Dis. 168:219-221.
23. Bauerfeind, P., R. M. Garner, and L. T. Mobley. 1996. Allelic exchange mutagenesis of NixA in Helicobacter pylori results in reduced nickel transport and urease activity. Infect. Immun. 64:2877-2880.
24. Bayerdorffer, E., A. Neubauer, B. Rudolph, C. Thiede, N. Lehn, S. Eidt, and M. Stolte. 1995. Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. Lancet 345:1591-1594.
25. Bayerdorffer, E., M. M. Ritter, R. Hatz, W. Brooks, G. Ruckdeschel, and M. Stolte. 1994. Healing of protein losing hypertrophic gastropathy by eradication of Helicobacter pylori - is Helicobacter pylori a pathogenic factor in Menetrier's disease? Gut 35:701-704.
26. Beji, A., F. Megraud, P. Vincent, F. Gavini, D. Izard, and H. Leclerc. 1988. GC content of DNA of Campylobacter pylori and other species belonging or related to the genus Campylobacter. Ann. Inst. Pasteur Microbiol. 139:527-534.
27. Benaissa, M., P. Babin, N. Quellard, L. Pezennec, Y. Cenatiempo, and J. L. Fauchere. 1996. Changes in Helicobacter pylori ultrastructure and antigens during conversion from the bacillary to the coccoid form. Infect. Immun. 64:2331-2335.
28. Blaser, M. J. 1987. Gastric campylobacter-like organisms, gastritis and peptic ulcer disease. Gastroenterology 93:371-383.
29. Blaser, M. J. 1990. Helicobacter pylori and the pathogenesis of gastroduodenal inflammation. J. Infect. Dis. 161:626-633.
30. Blaser, M. J. 1992. Hypotheses on the pathogenesis and natural history of Helicobacter pylori-induced inflammation. Gastroenterology 102:720-727.
31. Blaser, M. J. 1996. Genetic basis for heterogeneity of Helicobacter pylori, p. 33-39. In R. H. Hunt and G. N. J. Tytgat (ed.), Helicobacter pylori: basic mechanisms to clinical cure. Kluwer Academic Publishers, Dordrecht, The Netherlands.
32. Blaser, M. J. 1996. Role of vacA and the cagA locus of Helicobacter pylori in human disease. Aliment. Pharmacol. Ther. 10(Suppl. 1):73-7.
33. Blaser, M. J. 1997. All Helicobacter pylori strains are not created equal: should all be eliminated? Lancet 349:1020-1022.
34. Blaser, M. J., and J. Parsonnet. 1994. Parasitism by the "slow" bacterium Helicobacter pylori leads to altered gastric homeostasis and neoplasia. J. Clin. Invest. 94:4-8.
35. Blaser, M. J., G. I. Perez-Perez, H. Kleanthous, T. L. Cover, R. M. Peek, P. H. Chyou, G. N. Stemmermann, and A. Nomura. 1995. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res. 55:2111-2115.
36. Bode, G., P. Malfertheiner, G. Lehnhardt, M. Nilius, and H. Ditschuneit. 1993. Ultrastructural localization of urease of Helicobacter pylori. Med. Microbiol. Immunol. 182:233-242.
37. Bode, G., F. Mauch, H. Ditschuneit, and P. Malfertheiner. 1993. Identification of structures containing polyphosphate in Helicobacter pylori. J. Gen. Microbiol. 139:3029-3033.
38. Bode, G., F. Mauch, and P. Malfertheiner. 1993. The coccoid forms of Helicobacter pylori. Criteria for their viability. Epidemiol. Infect. 111:483-490.
39. Boren, T., P. Falk, K. A. Roth, G. Larson, and S. Normark. 1993. Attachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens. Science 262:1892-1895.
40. Borody, T. J., P. Andrews, G. Fracchia, S. Brandi, N. P. Shortis, and H. Bae. 1995. Omeprazole enhances efficacy of triple therapy in eradicating Helicobacter pylori. Gut 37:477-481.
41. Borody, T. J., N. P. Shortis, J. Chongnan, E. Reyes, and J. E. O'Shea. 1996. Eradication failure (EF) after H. pylori treatment - further therapies. Gastroenterology 110:A67.
42. Bottomley, J. R., C. L. Clayton, P. A. Chalk, and C. Kleanthous. 1996. Cloning, sequencing, expression, purification and preliminary characterization of a type II dehydroquinase from Helicobacter pylori. Biochem. J. 319:559-565.
43. Bukanov, N. O., and D. E. Berg. 1994. Ordered cosmid library and high-resolution physical-genetic map of Helicobacter pylori strain NCTC11638. Mol. Microbiol. 11:509-523.
44. 2 for growth. Microbiology 141:3113-3118.
45. Calam, J. 1995. Helicobacter pylori, acid and gastrin. Eur. J. Gastroenterol. Hepatol. 7:310-317.
46. Caselli, M., A. Aleotti, P. Boldrini, M. Ruina, and V. Alvisi. 1993. Ultrastructural patterns of Helicobacter pylori. Gut 34:1507-1509.
47. Cellini, L. 1996. Coccoid forms of Helicobacter pylori. J. Infect. Dis. 173: 1288-1289.
48. Censini, S., C. Lange, Z. Y. Xiang, J. E. Crabtree, P. Ghiara, M. Borodovsky, R. Rappuoli, and A. Covacci. 1996. Cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc. Natl. Acd. Sci. USA 93:14648-14653.
49. Chan, W. Y., P. K. Hui, K. M. Leung, J. Chow, F. Kwok, and C. S. Ng. 1994. Coccoid forms of Helicobacter pylori in the human stomach. Am. J. Clin. Pathol. 102:503-507.
50. Chen, M., A. Lee, and S. Hazell. 1992. Immunisation against gastric Helicobacter infection in a mouse Helicobacter felis model. Lancet 339:1120-1121.
51. Chen, T. S., S. H. Tsay, F. Y. Chang, and S. D. Lee. 1994. Effect of eradication of Helicobacter pylori on serum pepsinogen I, gastrin, and insulin in duodenal ulcer patients: a 12-month follow-up study. Am. J. Gastroenterol. 89:1511-1514.
52. 51a. Chong, S. K. F., Q. Lou, J. F. Fitzgerald, and C.-H. Lee. 1996. Evaluation of 16S rRNA gene PCR with primers Hp1 and Hp2 for detection of Helicobacter pylori. J. Clin. Microbiol. 34:2728-2730.
53. Christensen, A. H., T. Gjorup, J. Hilden, C. Fenger, B. Henriksen, M. Vyberg, K. Ostergaard, and B. F. Hansen. 1992. Observer homogeneity in the histologic diagnosis of Helicobacter pylori. Latent class analysis, kappa coefficient, and repeat frequency. Scand. J. Gastroenterol. 27:933-939.
54. Clyne, M., and B. Drumm. 1993. Adherence of Helicobacter pylori to primary human gastrointestinal cells. Infect. Immun. 61:4051-4057.
55. 53a. Cohen, H. 1996. Unpublished data.
56. Cohen, H., L. Bautista, H. Crowe, C. Johnson, S. L. Rose, and A. D. Pronovost. 1995. Comparison of culture and histology to seven commercial tests for Helicobacter pylori. Am. J. Gastroenterol. 90:1579.
57. Cohen, H., B. Retama, C. Johnson, S. Rose, A. Pronovost, and L. Laine. 1996. Evaluation of a rapid test to detect IgG antibodies to Helicobacter pylori using fingerstick whole blood samples. Gastroenterology 110:A83.
58. Collins, J. S., P. W. Hamilton, P. C. Watt, J. M. Sloan, and A. H. Love. 1989. Superficial gastritis and Campylobacterpylori in dyspeptic patients - a quantitative study using computer-linked image analysis. J. Pathol. 158:303-310.
59. Correa, P. 1992. Human gastric carcinogenesis: a multistep and multifactorial process-first American Cancer Society Award lecture on cancer epidemiology and prevention. Cancer Res. 52:6735-6740.
60. Corthesy-Theulaz, I., B. Corthesy, D. Bachman, N. Porta, A. C. Vaney, E. Saraga, P. Michetti, J. P. Kraehenbuhl, and A. L. Blum. 1996. Naked DNA immunization against Helicobacter infection. Gastroenterology 110:A889.
61. Corthesy-Theulaz, I., N. Porta, M. Glauser, E. Saraga, A. C. Vaney, R. Haas, J. P. Kraehenbuhl, A. L. Blum, and P. Michetti. 1995. Oral immunization with Helicobacter pylori urease B subunit as a treatment against Helicobacter infection in mice. Gastroenterology 109:115-121.
62. Coudron, P. E. and C. W. Stratton. 1995. Factors affecting growth and susceptibility testing of Helicobacter pylori in liquid media. J. Clin. Microbiol. 33:1028-1030.
63. Coudron, P. E. and C. W. Stratton. 1995. Use of time-kill methodology to assess antimicrobial combinations against metronidazole-susceptible and metronidazole-resistant strains of Helicobacter pylori. Antimicrob. Agents Chemother. 39:2641-2644.
64. Covacci, A., S. Censini, M. Bugnoli, R. Petracca, D. Burroni, G. Macchia, A. Massone, E. Papini, Z. Xiang, and N. Figura. 1993. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc. Natl. Acd. Sci. USA 90:5791-5795.
65. Cover, T. L., and M. J. Blaser. 1992. Purification and characterization of the vacuolating toxin from Helicobacter pylori. J. Biol. Chem. 267:10570-10575.
66. Cover, T. L., P. Cao, U. K. Murthy, M. S. Sipple, and M. J. Blaser. 1992. Serum neutralizing antibody response to the vacuolating cytotoxin of Helicobacter pylori. J. Clin. Invest. 90:913-918.
67. + Helicobacler pylori strains. J. Clin. Microbiol. 33:1496-1500.
68. Cover, T. L., S. A. Halter, and M. J. Blaser. 1992. Characterization of HeLa cell vacuoles induced by Helicobacter pylori broth culture supernatant. Hum. Pathol. 23:1004-1010.
69. Cover, T. L., W. Puryear, G. I. Perez-Perez, and M. J. Blaser. 1991. Effect of urease on HeLa cell vacuolation induced by Helicobacter pylori cytotoxin. Infect. Immun. 59:1264-1270.
70. Cover, T. L., L. Y. Reddy, and M. J. Blaser. 1993. Effects of ATPase inhibitors on the response of HeLa cells to Helicobacter pylori vacuolating toxin. Infect. Immun. 61:1427-1431.
71. Cover, T. L., M. K. Tummuru, P. Cao, S. A. Thompson, and M. J. Blaser. 1994. Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacier pylori strains. J. Biol. Chem. 269:10566-10573.
72. Crabtree, J. E., A. Covacci, S. M. Farmery, Z. Xiang, D. S. Tompkins, S. Perry, I. J. Lindley, and R. Rappuoli. 1995. Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with cagA positive phenotype. J. Clin. Pathol. 48:41-45.
73. Craft, J. C., C. Olson, N. Siepinan, and A. Edwards. 1995. Clarithromycin resistance in US and European patients treated with clarithromycin (CL) and omeprazole (OM) for duodenal ulcer disease with H. pylori (HP) infection. Am. J. Gastroenterol. 90:1579.
74. Cutler, A., A. Schubert, and T. Schubert. 1993. Role of Helicobacter pylori serology in evaluating treatment success. Dig. Dis. Sci. 38:2262-2266.
75. Cutler, A. F., S. Havstad, C. K. Ma, M. J. Blaser, G. I. Perez-Perez, and T. T. Schubert. 1995. Accuracy of invasive and noninvasive tests to diagnose Helicobacter pylori infection. Gastroenterology 109:136-141.
76. Czinn, S. J., A. Cai, and J. G. Nedrud. 1993. Protection of germ-free mice from infection by Helicobacter felis active oral or passive IgA immunization. Vaccine 11:637-642.
77. Davies, G. R., N. Banatvala, C. E. Collins, M. T. Sheaff, Y. Abdi, L. Clements, and D. S. Rampton. 1994. Relationship between infective load of Helicobacter pylori and reactive oxygen metabolite production in antral mucosa. Scand. J. Gastroenterol. 29:419-424.
78. Davies, G. R., N. J. Simmonds, T. R. Stevens, M. T. Sheaff, N. Banatvala, I. F. Laurenson, D. R. Blake, and D. S. Rampton. 1994. Helicobacter pylori stimulates antral mucosal reactive oxygen metabolite production in vivo. Gut 35:179-185.
79. Debets-Ossen Kopp, Y. J., M. Sparrius, J. G. Kusters, J. J. Kolkman, and C. M. J. E. Vandenbrouckegrauls. 1996. Mechanism of clarithromycin resistance in clinical isolates of Helicobacter pylori. FEMS Microbiol. Lett. 142:37-42.
80. de Boer, W., W. Driessen, A. Jansz, and G. Tytgat. 1995. Effect of acid suppression on efficacy of treatment for Helicobacter pylori infection. Lancet 345:817-820.
81. de Boer, W. A., W. Driessen, and G. N. J. Tytgat. 1995. Only four days of quadruple therapy can effectively cure Helicobacter pylori infection. Aliment. Pharmacol. Ther. 9:633-638.
82. de Boer, W. A., R. J. van Etten, R. W. Schade, M. E. Ouwehand, P. M. Schneeberger, and G. N. Tytgat. 1996. 4-day Iansoprazole quadruple therapy: a highly effective cure for Helicobacter pylori infection. Am. J. Gastroenterol. 91:1778-1782.
83. Debongnie, J. C., M. Donnay, and J. Mairesse. 1995. Gastrosprillium hominis ("Helicobacter heilmanii"): a cause of gastritis, sometimes transient, better diagnosed by touch cytology? Am. J. Gastroenterol. 90:411-416.
84. de Cothi, G. A., K. M. Newbold, and H. J. O'Connor. 1989. Campylobacter-like organisms and heterotopic gastric mucosa in Meckel's diverticula. J. Clin. Pathol. 42:132-134.
85. Desai, M., D. Linton, R. J. Owen, and J. Stanley. 1994. Molecular typing of Helicobacter pylori isolates from asymptomatic, ulcer and gastritis patients by urease gene polymorphism. Epidemiol. Infect. 112:151-160.
86. Devreker, T., C. A. M. McNulty, J. C. Uff, S. P. Wilkinson, and M. W. L. Gear. 1987. New spiral bacterium in gastric mucosa. Lancet ii:96.
87. Dickey, W., B. D. Kenny, and J. B. Mcconnell. 1996. Effect of proton pump inhibitors on the detection of Helicobacter pylori in gastric biopsies. Aliment. Pharmacol. Ther. 10:289-293.
88. Dixon, M. F. 1995. Histological responses to Helicobacter pylori infection: gastritis, atrophy and preneoplasia. Baillieres Clin. Gastroenterol. 9:467-486.
89. Dixon, M. F., R. M. Genta, J. H. Yardley, P. Correa, K. P. Batts, B. B. Dahms, M. I. Filipe, R. C. Haggitt, J. Haot, P. K. Hui, J. Lechago, K. Lewin, J. A. Offerhaus, A. B. Price, R. H. Riddell, P. Sipponen, E. Solcia, and H. Watanabe. 1996. Classification and grading of gastritis - the updated Sydney system. Am. J. Surg. Pathol. 20:1161-1181.
90. Doidge, C., I. Crust, A. Lee, F. Buck, S. Hazell, and U. Manne. 1994. Therapeutic immunisation against Helicobacter infection. Lancet 343:914-5.
91. Doig, P., M. M. Exner, R. E. Hancock, and T. J. Trust 1995. Isolation and characterization of a conserved porin protein from Helicobacter pylori. J. Bacteriol. 177:5447-5452.
92. Doig, P., and T. J. Trust. 1994. Identification of surface-exposed outer membrane antigens of Helicobacter pylori. Infect. Immun. 62:4526-4533.
93. 90a. Dore, M. P., A. R. Sepulveda, I. Mura, G. Realdi, M. S. Osato, and D. Y. Graham. 1997. Explanation for variability of omeprazole amoxicillin therapy? Tolerance of H. pylori to amoxicillin. Gastroenterology 112:A105.
94. Dore-Davin, C., P. Michetti, E. Saraga, A. L. Blum, and I. Corthesy-Theulaz. 1996. A 37 kDa fragment of UreB is sufficient to confer protection against Helicobacter felts infection in mice. Gastroenterology 110:A97.
95. Drake, I. M., M. J. Davies, N. P. Mapstone, M. F. Dixon, C. J. Schorah, K. L. White, D. M. Chalmers, and A. T. Axon. 1996. Ascorbic acid may protect against human gastric cancer by scavenging mucosal oxygen radicals. Carcinogenesis 17:559-562.
96. Drouet, E. B., H. P. De Muntclos, M. Andujar, M. Boude, J. A. Grimaud, and G. A. Denoyel. 1993. Partial characterization of an external polysaccharide of Helicobacter pylori by using an immunoglobulin M monoclonal antibody. Infect. Immun. 61:2732-2736.
97. Dubois, A., N. Fiala, L. M. Heman-Ackah, E. S. Drazek, A. Tarnawski, W. N. Fishbein, G. I. Perez-Perez, and M. J. Blaser. 1994. Natural gastric infection with Helicobacter pylori in monkeys: a model for spiral bacteria infection in humans. Gastroenterology 106:1405-1417.
98. Dunn, B. E., G. P. Campbell, G. I. Perez-Perez, and M. J. Blaser. 1990. Purification and characterization of urease from Helicobacter pylori. J. Biol. Chem. 265:9464-9469.
99. Dunn, B. E., N. B. Vakil, B. G. Schneider, J. B. Zitzer, T. Puetz, and S. H. Phadnis. 1997. Localization of Helicobacter pylori urease and heat shock protein homolog in human gastric biopsies. Infect. Immun. 65:1181-1188.
100. Dunn, B. E., G. I. Perez-Perez, and M. J. Blaser. 1989. Two-dimensional gel electrophoresis and immunoblotting of Campylobacter pylori proteins. Infect. Immun. 57:1825-1833.
101. Dunn, B. E., R. M. Roop, II, C. C. Sung, S. A. Sharma, G. I. Perez-Perez, and M. J. Blaser. 1992. Identification and purification of a cpn60 heat shock protein homolog from Helicobacter pylori. Infect. Immun. 60:1946-1951.
102. Dunn, B. E., C. C. Sung, N. S. Taylor, and J. G. Fox. 1991. Purification and characterization of Helicobacter mustelae urease. Infect. Immun. 59:3343-3345.
103. Eaton, K. A., C. L. Brooks, D. R. Morgan, and S. Krakowka. 1991. Essential role of urease in pathogenesis of gastritis induced by Helicobacter pylori in gnotobiotic piglets. Infect. Immun. 59:2470-2475.
104. Eaton, K. A., C. E. Catrenich, K. M. Makin, and S. Krakowka. 1995. Virulence of coccoid and bacillary forms of Helicobacter pylori in gnotobiotic piglets. J. Infect. Dis. 171:459-462.
105. Eaton, K. A. and S. Krakowka. 1994. Effect of gastric pH on urease-dependent colonization of gnotobiotic piglets by Helicobacter pylori. Infect. Immun. 62:3604-3607.
106. Eaton, K. A., D. R. Morgan, and S. Krakowka. 1989. Campylobacter pylori virulence factors in gnotobiotic piglets. Infect. Immun. 57:1119-1125.
107. Eaton, K. A., D. R. Morgan, and S. Krakowka. 1992. Motility as a factor in the colonisation of gnotobiotic piglets by Helicobacter pylori. J. Med. Microbiol. 37:123-127.
108. Eaton, K. A., S. Suerbaum, C. Josenhans, and S. Krakowka. 1996. Colonization of gnotobiotic piglets by Helicobacter pylori deficient in two flagellin genes. Infect. Immun. 64:2445-2448.
109. Eidt, S., M. Stolte, and R. Fischer. 1994. Helicobacter pylori gastritis and primary gastric non-Hodgkin's lymphomas. J. Clin. Pathol. 47:436-439.
110. el-Zaatari, F. A., A. M. Nguyen, R. M. Genta, P. D. Klein, and D. Y. Graham. 1995. Determination of Helicobacter pylori status by reverse transcription-polymerase chain reaction. Comparison with urea breath test. Dig. Dis. Sci. 40:109-113.
111. el-Zimaity, H. M., M. T. al-Assi, R. M. Genta, and D. Y. Graham. 1995. Confirmation of successful therapy of Helicobacter pylori infection: number and site of biopsies or a rapid urease test. Am. J. Gastroenterol. 90:1962-1964.
112. el-Zimaity, H. M., D. Y. Graham, M. T. al-Assi, H. Malaty, T. J. Karttunen, D. P. Graham, R. M. Huberman, and R. M. Genta. 1996. Interobserver variation in the histopathological assessment of Helicobacter pylori gastritis. Hum. Pathol. 27:35-41.
113. Eschweiler, B., B. Bohrmann, B. Gerstenecker, E. Schiltz, and M. Kist. 1993. In situ localization of the 60 k protein of Helicobacter pylori, which belongs to the family of heat shock proteins, by immuno-electron microscopy. Int. J. Med. Microbiol. Virol. Parasitol. Infect. Dis. 280:73-85.
114. Evans, D. G., T. K. Karjalainen, D. J. Evans, Jr., D. Y. Graham, and C. H. Lee. 1993. Cloning, nucleotide sequence, and expression of a gene encoding an adhesin subunit protein of Helicobacter pylori. J. Bacteriol. 175:674-683.
115. Evans, D. J., Jr., D. G. Evans, L. Engstrand, and D. Y. Graham. 1992. Urease-associated heat shock protein of Helicobacter pylori. Infect. Immun. 60:2125-2127.
116. Evans, D. J., Jr., D. G. Evans, D. Y. Graham, and P. D. Klein. 1989. A sensitive and specific serologic test for detection of Campylobacter pylori infection. Gastroenterology 96:1004-1008.
117. Evans, D. J., Jr., D. G. Evans, T. Takemura, H. Nakano, H. C. Lampert, D. Y. Graham, D. N. Granger, and P. R. Kvietys. 1995. Characterization of a Helicobacter pylori neutrophil-activating protein. Infect. Immun. 63:2213-2220.
118. Exner, M. M., P. Doig, T. J. Trust, and R. E. Hancock. 1995. Isolation and characterization of a family of porin proteins from Helicobacter pylori. Infect. Immun. 63:1567-1572.
119. 115a. Fabry, W., P. Okemo, and R. Ansborg. 1996. Activity of East African medicinal plants against Helicobacter pylori. Chemotherapy 42:315-317.
120. Falk, P., K. A. Roth, T. Boren, T. U. Westblom, J. I. Gordon, and S. Normark. 1993. An in vitro adherence assay reveals that Helicobacter pylori exhibits cell lineage-specific tropism in the human gastric epithelium. Proc. Natl. Acd. Sci. USA 90:2035-2039.
121. Fallone, C. A., M. Elizov, P. Cleland, J. A. Thompson, G. E. Wild, J. Lough, J. Faria, and A. N. Barkun. 1996. Detection of Helicobacter pylori infection by saliva IgG testing. Am. J. Gastroenterol. 91:1145-1149.
122. Fan, X. G., A. Chua, X. J. Fan, and P. W. Keeling. 1995. Increased gastric production of interleukin-8 and tumour necrosis factor in patients with Helicobacter pylori infection. J. Clin. Pathol. 48:133-136.
123. Ferrero, R. L., J. M. Thiberge, M. Huerre, and A. Labigne. 1994. Recombinant antigens prepared from the urease subunits of Helicobacter spp. -evidence for protection in a mouse model of gastric infection. Infect. Immun. 62:4981-4989.
124. Ferrero, R. L., J. M. Thiberge, I. Kansau, N. Wuscher, M. Huerre, and A. Labigne. 1995. The GroES homolog of Helicobacter pylori confers protective immunity against mucosal infection in mice. Proc. Natl. Acd. Sci. USA 92:6499-6503.
125. Fiedorek, S. C., H. M. Malaty, D. L. Evans, C. L. Pumphrey, H. B. Casteel, D. J. Evans, Jr., and D. Y. Graham. 1991. Factors influencing the epidemiology of Helicobacter pylon infection in children. Pediatrics 88:578-582.
126. Forbes, K. J., Z. Fang, and T. H. Pennington. 1995. Allelic variation in the Helicobacter pylori flagellin genes flaA and flaB: its consequences for strain typing schemes and population structure. Epidemiol. Infect. 114:257-266.
127. Forman, D., D. G. Newell, F. Fullerton, J. W. Yarnell, A. R. Stacey, N. Wald, and F. Sitas. 1991. Association between infection with Helicobacter pylori and risk of gastric cancer: evidence from a prospective investigation. Br. Med. J. 302:1302-1305.
128. Fox, J. G., M. Batchelder, R. Marini, L. Yan, L. Handt, X. Li, B. Shames, A. Hayward, J. Campbell, and J. C. Murphy. 1995. Helicobacter pylori-induced gastritis in the domestic cat. Infect. Immun. 63:2674-2681.
129. Foxall, P. A., L. T. Hu, and H. L. Mobley. 1992. Use of polymerase chain reaction-amplified Helicobacter pylori urease structural genes for differentiation of isolates. J. Clin. Microbiol. 30:739-741.
130. Garner, J. A. and T. L. Cover. 1995. Analysis of genetic diversity in cytotoxin-producing and non-cytotoxin-producing Helicobacter pylori strains. J. Infect. Dis. 172:290-293.
131. Ge, Z., K. Hiratsuka, and D. E. Taylor. 1995. Nucleotide sequence and mutational analysis indicate that two Helicobacter pylori genes encode a p-type ATPase and a cation-binding protein associated with copper transport. Mol. Microbiol. 15:97-106.
132. Geis, G., S. Suerbaum, B. Forsthoff, H. Leying, and W. Opferkuch. 1993. Ultrastructure and biochemical studies of the flagellar sheath of Helicobacter pylori. J. Med. Microbiol. 38:371-377.
133. Geller, S. A. 1996. Small organism, many challenges. Hum. Pathol. 27:1-4.
134. Genta, R. M. and D. Y. Graham. 1994. Comparison of biopsy sites for the histopathologic diagnosis of Helicobacter pylori: a topographic study of H. pylori density and distribution. Gastrointest. Endosc. 40:342-345.
135. Genta, R. M., and D. Y. Graham. 1994. Helicobacter pylori: the new bug on the (paraffin) block. Virchows Arch. 425:339-347.
136. Genta, R. M., I. E. Gurer, D. Y. Graham, B. Krishnan, A. M. Segura, O. Gutierrez, J. G. Kim, and J. L. Burchette. 1996. Adherence of Helicobacter pylori to areas of incomplete intestinal metaplasia in the gastric mucosa. Gastroenterology 111:1206-1211.
137. Genta, R. M., H. W. Hamner, and D. Y. Graham. 1993. Gastric lymphoid follicles in Helicobacter pylori infection: frequency, distribution, and response to triple therapy. Hum. Pathol. 24:577-583.
138. Genta, R. M., G. O. Robason, and D. Y. Graham. 1994. Simultaneous visualization of Helicobacter pylori and gastric morphology: a new stain. Hum. Pathol. 25:221-226.
139. Glupczynski, Y. 1992. Results of a multicenter European survey in 1991 of metronidazole resistance in Helicobacter pylori. Eur. J. Clin. Microbiol. Infect. Dis. 11:777-781.
140. Glupczynski, Y., A. Burette, E. Koster, J.-F. Nyst, M. Deltenre, S. Cadranel, L. Bourdeaux, and D. DeVos. 1990. Metronidazole resistance in Helicobacter pylori. Lancet 335:976-977.
141. Go, M. F., V. Kapur, D. Y. Graham, and J. M. Musser. 1996. Population genetic analysis of Helicobacter pylori by multilocus enzyme electrophoresis: extensive allelic diversity and recombinational population structure. J. Bacteriol. 178:3934-3938.
142. Gold, B. D., M. Huesca, P. M. Sherman, and C. A. Lingwood. 1993. Helicobacter mustelae and Helicobacter pylori bind to common lipid receptors in vitro. Infect. Immun. 61:2632-2638.
143. Goodwill, C. S. and J. A. Armstrong. 1990. Microbiological aspects of Helicobacter pylori (Campylobacter pylori). Eur. J. Clin. Microbiol. 9:1-13.
144. Goodwill, C. S, R. K. McCulloch, J. A. Armstrong, and S. H. Wee. 1987. Unusual cellular fatty acids and distinctive ultrastructure in a new spiral bacterium (Campylobacter pyloridis) from the human gastric mucosa. J. Med. Microbiol. 19:257-267.
145. Graham, D. Y., W. A. de Boer, and G. N. Tytgat. 1996. Choosing the best anti-Helicobacler pylori therapy: effect of antimicrobial resistance. Am. J. Gastroenterol. 91:1072-1076.
146. Graham, D. Y., H. Malary, H. M. el-Zimaity, R. M. Genta, R. A. Cole, M. T. al-Assi, M. M. Yousfi, and G. A. Neil. 1995. Variability with omeprazole-amoxicillin combinations for treatment of Helicobacter pylori infection. Am. J. Gastroenterol. 90:1415-1418.
147. Graham, D. Y., H. M. Malaty, D. G. Evans, D. J. Evans, P. D. Klein, and E. Adam. 1991. Epidemiology of Helicobacter pylori in an asymptomatic population in the United States. Gastroenterology 100:1495-1501.
148. Hachem, C. Y., J. E. Clarridge, D. G. Evans, and D. Y. Graham. 1995. Comparison of agar based media for primary isolation of Helicobacter pylori. J. Clin. Pathol. 48:714-716.
149. Han, S. W., R. Flamm, C. Y. Hachem, H. Y. Kim, J. E. Clarridge, D. G. Evans, J. Beyer, J. Drnec, and D. Y. Graham. 1995. Transport and storage of Helicobacter pylori from gastric mucosal biopsies and clinical isolates. Eur. J. Clin. Microbiol. Infect. Dis. 14:349-352.
150. Harris, P. R., H. L. Mobley, G. I. Perez-Perez, M. J. Blaser, and P. D. Smith. 1996. Helicobacter pylori urease is a potent stimulus of mononuclear phagocyte activation and inflammatory cytokine production. Gastroenterology 111:419-425.
151. Hawtin, P. R., A. R. Stacey, and D. G. Newell. 1990. Investigation of the structure and localization of the urease of Helicobacter pylori using monoclonal antibodies. J. Gen. Microbiol. 136:1995-2000.
152. Hazell, S. L., and D. Y. Graham. 1990. Unsaturated fatty acids and viability of Helicobacter (Campylobacter) pylori. J. Clin. Microbiol. 28:1060-1061.
153. Henriksen, T. H., O. Brorson, R. Schoyen, T. Thoresen, D. Setegn, and T. Madebo. 1995. Rapid growth of Helicobacter pylori. Eur. J. Clin. Microbiol. Infect. Dis. 14:1008-1011.
154. Hirai, M., T. Azuma, S. Ito, T. Kato, Y. Kohli, and N. Fujiki. 1994. High prevalence of neutralizing activity to Helicobacter pylori cytotoxin in serum of gastric-carcinoma patients. Int. J. Cancer 56:56-60.
155. Hirmo, S., S. Kelm, R. Schauer, B. Nilsson, and T. Wadstrom. 1996. Adhesion of Helicobacter pylori strains to alpha-2,3-linked sialic acids. Glycoconj. J. 13:1005-1011.
156. Hirschl, A. M., and M. L. Rotter. 1996. Serological tests for monitoring Helicobacter pylori eradication treatment. J. Gastroenterol. 31:33-36.
157. Hu, L. T., and H. L. Mobley. 1990. Purification and N-terminal analysis of urease from Helicobacter pylori. Infect. Immun. 58:992-998.
158. Hu, L. T., and H. L. Mobley. 1993. Expression of catalytically active recombinant Helicobacter pylori urease at wild-type levels in Escherichia coli. Infect. Immun. 61:2563-2569.
159. Huang, J., P. W. O'Toole, P. Doig, and T. J. Trust. 1995. Stimulation of interleukin-8 production in epithelial cell lines by Helicobacter pylori. Infect. Immun. 63:1732-1738.
160. Hunter, F. M., P. Correa, E. Fontham, B. Ruiz, M. Sobhan, and I. M. Samloff. 1993. Serum pepsinogens as markers of response to therapy for Helicobacter pylori gastritis. Dig. Dis. Sci. 38:2081-2086.
161. Husson, M. O., D. Legrand, G. Spik, and H. Leclerc. 1993. Iron acquisition by Helicobacter pylori: importance of human lactoferrin. Infect. Immun. 61:2694-2697.
162. Illingworth, D. S., K. S. Walter, P. L. Griffiths, and R. Barclay. 1993. Siderophore production and iron-regulated envelope proteins of Helicobacter pylori. Int. J. Med. Microbiol. Virol. Parasitol. Infect. Dis. 280:113-119.
163. Inouye, H., I. Yamamoto, N. Tanida, J. Mikami, K. Tamura, T. Ohno, M. Kano, and T. Shimoyama. 1989. Campylobacter pylori in Japan: bacteriologic features and prevalence in healthy subjects and patients with gastroduodenal disorders. Gastroenterol. Japan. 24:494-504.
164. Janas, B., E. Czkwianianc, L. Bak-Romaniszyn, H. Bartel, D. Tosik, and I. Planeta-Malecka. 1995. Electron microscopic study of association between coccoid forms of Helicobacter pylori and gastric epithelial cells. Am. J. Gastroenterol. 90:1829-1833.
165. Jiang, Q., K. Hiratsuka, and D. E. Taylor. 1996. Variability of gene order in different Helicobacter pylori strains contributes to genome diversity. Mol. Microbiol. 20:833-842.
166. Jones, D. M., A. M. Lessells, and J. Eldridge. 1984. Campylobacter-like organisms on the gastric mucosa: culture, histological and serological studies. J. Clin. Pathol. 37:1002-1006.
167. Jonkers, D., E. Stobberingh, and R. Stockbrugger. 1996. Omeprazole inhibits growth of gram-positive and gram-negative bacteria including Helicobacter pylori in vitro. J. Antimicrob. Chemother. 37:145-150.
168. Josenhans, C., A. Labigne, and S. Suerbaum. 1995. Comparative ultrastructural and functional studies of Helicobacter pylori and Helicobacter mustelae flagellin mutants: both flagellin subunits, FlaA and FlaB, are necessary for full motility in Helicobacter species. J. Bacteriol. 177:3010-3020.
169. Karim, Q. N., and R. P. H. Logan. 1996. Emerging patterns of Helicobacter pylori (H. pylori) antimicrobial resistance in Europe. Gut 39:A51.
170. Karnes, W. E., Jr., I. M. Samloff, M. Siurala, M. Kekki, P. Sipponen, S. W. Kim, and J. H. Walsh. 1991. Positive serum antibody and negative tissue staining for Helicobacter pylori in subjects with atrophic body gastritis. Gastroenterology 101:167-174.
171. Kato, S., M. Onda, N. Matsukura, A. Tokunaga, N. Matsuda, K. Yamashita, and P. G. Shields. 1996. Genetic polymorphisms of the cancer related gene and Helicobacter pylori infection in Japanese gastric cancer patients. An age and gender matched case-control study. Cancer 77:1654-61.
172. Katoh, M., D. Saito, T. Noda, S. Yoshida, Y. Oguro, Y. Vazaki, T. Sugimura, and M. Terada. 1993. Helicobacter pylori may be transmitted through gastrofiberscope even after manual hyamine washing. Jpn. J. Cancer Res. 84:117-119.
173. Kelly, S. M., M. C. Pitcher, S. M. Farmery, and G. R. Gibson. 1994. Isolation of Helicobacter pylori from feces of patients with dyspepsia in the United Kingdom. Gastroenterology 107:1671-1674.
174. Kirkland, T., S. Viriyakosol, G. I. Perez-Perez, and M. J. Blaser. 1997. Helicobacter pylori lipopolysaccharide can activate 70Z/3 cells via CD14. Infect. Immun. 65:604-608.
175. Kist, M., C. Spiegelhalder, T. Moriki, and H. E. Schaefer. 1993. Interaction of Helicobacter pylori (strain 151) and Campylobacter coli with human peripheral polymorphonuclear granulocytes. Int. J. Med. Microbiol. Virol. Parasitol. Infect. Dis. 280:58-72.
176. Kleanthous, H., C. L. Clayton, and S. Tabaqchali. 1991. Characterization of a plasmid from Helicobacter pylori encoding a replication protein common to plasmids in gram-positive bacteria. Mol. Microbiol. 5:2377-2389.
177. Klein, P. D., D. Y. Graham, A. Gaillour, A. R. Opekun, and E. O. Smith. 1991. Water source as risk factor for Helicobacter pylori infection in Peruvian children. Lancet 337:1503-1506.
178. 13C urea breath test. Am. J. Gastroenterol. 91:690-694.
179. Knipp, U., S. Birkholz, W. Kaup, and W. Opferkuch. 1993. Immune suppressive effects of Helicobacter pylori on human peripheral blood mononuclear cells. Med. Microbiol. Immunol. 182:63-76.
180. Kobayashi, Y., K. Okazaki, and K. Murakami. 1993. Adhesion of Helicobacter pylori to gastric epithelial cells in primary cultures obtained from stomachs of various animals. Infect. Immun. 61:4058-4063.
181. 13C-urea breath test. Lancet 345:961-962.
182. Kolts, B. E., B. Joseph, S. R. Achem, T. Bianchi, and C. Monteiro. 1993. Helicobacter pylori detection: a quality and cost analysis. Am. J. Gastroenterol. 88:650-655.
183. Kosunen, T. U., K. Seppala, S. Sarna, and P. Sipponen. 1992. Diagnostic value of decreasing IgG, IgA, and IgM antibody titres after eradication of Helicobacter pylori. Lancet 339:893-895.
184. Kreiss, C., T. Buclin, M. Cosma, I. Corthesy-Theulaz, N. Porta, M. Glauser, M. Appenzeller, J. Pappo, R. Nichols, M. Stolte, T. Monath, A. L. Blum, and P. Michetti. 1996. Oral immunization with recombinant urease without adjuvant in H. pylori-infected humans. Gut 39:A39.
185. Krishnamurthy, P., M. Parlow, J. Zitzer, N. Vakil, S. H. Phadnis, and B. E. Dunn. 1997. H. pylori containing only cytoplasmic urease are acid sensitive, abstr. 4514. In Proceedings of the American Gastroenterological Association Annual Meeting.
186. Kuipers, E. J., G. Pals, A. S. Pena, C. W. van Uffelen, A. Kok, B. D. Westerveld, and S. G. Meuwissen. 1996. Helicobacter pylori, pepsinogens and gastrin: relationship with age and development of atrophic gastritis. Eur. J. Gastroenterol. Hepatol. 8:153-156.
187. Lage, A. P., E. Godfroid, A. Fauconnier, A. Burette, J. P. Butzler, A. Bollen, and Y. Glupczynski. 1995. Diagnosis of Helicobacter pylori infection by PCR: comparison with other invasive techniques and detection of cagA gene in gastric biopsy specimens. J. Clin. Microbiol. 33:2752-2756.
188. Laine, L., K. Bartizal, L. Kong, P. Scott, and G. Neil. 1995. Evidence against oral-oral transmission of H. pylori: lack of salivary H. pylori detected by polymerase chain reaction (PCR). Gastroenterology 108:A142.
189. Laine, L., D. Chung, C. Stein, I. El-Beblawi, V. Sharma, and P. Chandrasoma. 1996. The influence of size or number of biopsies on rapid urease test results: a prospective evaluation. Gastroinest. Endosc. 43:49-53.
190. Laine, L., H. Cohen, R. Sloane, M. Marin-Sorensen, and W. M. Weinstein. 1995. Interobserver agreement and predictive value of endoscopie findings for H. pylori and gastritis in normal volunteers. Gastrointest. Endosc. 42: 420-423.
191. Laine, L., R. Estrada, D. N. Lewin, and H. Cohen. 1996. The influence of warming on rapid urease test results - a prospective evaluation. Gastrointest. Endosc. 44:429-432.
192. Laine, L., R. Estrada, M. Trujillo, and S. Emami. 1997. Randomized comparison of ranitidine bismuth citrate (RBC) based triple therapies for H. pylori (HP). Gastroenterology 112:A192.
193. Laine, L., D. Lewin, W. Naritoku, R. Estrada, and H. Cohen. 1996. Prospective comparison of commercially available rapid urease tests for the diagnosis of Helicobacter pylori. Gastrointest. Endosc. 44:523-526.
194. Laine, L., D. N. Lewin, W. Naritoku, and H. Cohen. 1997. Prospective comparison of H&E, Giemsa and Genta stains for the diagnosis of Helicobacter pylori. Gastrointest. Endosc. 45:463-467.
195. Laine, L., C. Stein, and G. Neil. 1995. Limited efficacy of omeprazole-based dual and triple therapy for Helicobacter pylori: a randomized trial employing "optimal" dosing. Am. J. Gastroenterol. 90:1407-1410.
196. Langenberg, M. L., G. N. J. Tytgat, M. E. I. Schipper, P. J. G. M. Rietra, and H. C. Zanen. 1984. Campylobacter-like organisms in the stomach of patients and healthy individuals. Lancet 1:1348.
197. Lee, C. K., R. Weltzin, W. D. Thomas, Jr., H. Kleanthous, T. H. Ermak, G. Soman, J. E. Hill, S. K. Ackerman, and T. P. Monath. 1995. Oral immunization with recombinant Helicobacter pylori urease induces secretory IgA antibodies and protects mice from challenge with Helicobacier felis. J. Infect. Dis. 172:161-172.
198. Lelwala-Guruge, J., F. Ascencio, A. S. Kreger, A. Ljungh, and T. Wadstrom. 1993. Isolation of a sialic acid-specific surface haemagglutinin of Helicobacter pylori strain NCTC 11637. Int. J. Med. Microbiol. Virol. Parasitol. Infect. Dis. 280:93-106.
199. Lelwala-Guruge, J., F. Ascencio, A. Ljungh, and T. Wadstrom. 1993. Rapid detection and characterization of sialic acid-specific lectins of Helicobacter pylori. APMIS 101:695-702.
200. Leunk, K. D., P. T. Johnson, B. C. David, W. G. Kraft, and D. R. Morgan. 1988. Cytotoxic activity in broth-culture filtrates of Campylobacter pylori. J. Med. Microbiol. 26:93-99.
201. Li, C. F., T. Z. Ha, D. A. Ferguson, D. S. Chi, R. G. Zhao, N. R. Patel, G. Krishnaswamy, and E. Thomas. 1996. A newly developed PCR assay of H. pylori in gastric biopsy, saliva, and feces - evidence of high prevalence of H. pylori in saliva supports oral transmission. Dig. Dis. Sci. 41:2142-2149.
202. Lind, T., S. Velduyzen van Zanten, and P. Unge. 1996. Eradication of Helicobacter pylori using one week triple therapies combining omeprazole with two antimicrobials. The Mach 1 study. Helicobacter 1:138-144.
203. Lingwood, C. A., G. Wasfy, H. Han, and M. Huesca. 1993. Receptor affinity purification of a lipid-binding adhesin from Helicobacter pylori. Infect. Immun. 61:2474-2478.
204. Lip, G. Y. H., R. Wise, and G. Beevers. 1996. Study shows association between H. pylori infection and hypertension. Br. Med. J. 312:250-251.
205. Logan, R. P., M. M. Walker, J. J. Misiewicz, P. A. Gummett, Q. N. Karim, and J. H. Baron. 1995. Changes in the intragastric distribution of Helicobacter pylori during treatment with omeprazole. Gut 36:12-16.
206. Logan, R. P. H., and D. E. Berg. 1996. Genetic diversity of Helicobacter pylori. Lancet 348:1462-1463.
207. Loy, C. T., L. M. Irwig, P. H. Katelaris, and N. J. Talley. 1996. Do commercial serological kits for Helicobacter pylori infection differ in accuracy? A meta-analysis. Am. J. Gastroenterol. 91:1138-1144.
208. Luke, C. J., and C. W. Penn. 1995. Identification of a 29 kDa flagellar sheath protein in Helicobacter pylori using a murine monoclonal antibody. Microbiology 141:597-604.
209. Macchia, G., A. Massone, D. Burroni, A. Covacci, S. Censini, and R. Rappuoli. 1993. The hsp60 protein of Helicobacter pylori; structure and immune response in patients with gastroduodenal diseases. Mol. Microbiol. 9:645-652.
210. Mannick, E. E., L. E. Bravo, G. Zarama, J. L. Realpe, X. J. Zhang, B. Ruiz, E. T. Fontham, R. Mera, M. J. Miller, and P. Correa. 1996. Inducible nitric oxide synthase, nitrotyrosine, and apoptosis in Helicobacier pylori gastritis: effect of antibiotics and antioxidants. Cancer Res. 56:3238-3243.
211. Marcelli, S. W., H. T. Chang, T. Chapman, P. A. Chalk, R. J. Miles, and R. K. Poole. 1996. The respiratory chain ni Helicobacter pylori: identification of cytochromes and the effects of oxygen on cytochrome and menaquinone levels. FEMS Microbiol. Lett. 138:59-64.
212. Marchetti, M., B. Arico, D. Burroni, N. Figura, R. Rappuoli, and P. Ghiara. 1995. Development of a mouse model of Helicobacter pylori infection that mimics human disease. Science 267:1655-1658.
213. Marchini, A., M. d'Apolito, P. Massari, M. Atzeni, M. Copass, and R. Olivieri. 1995. Cyclodextrins for growth of Helicobacter pylori and production of vacuolating cytotoxin. Arch. Microbiol. 164:290-293.
214. Marshall, B. J. 1989. History of the discovery of Campylobacter pylori, p. 7-24. In M. J. Blaser (ed.), Campylobacter pylori in gastritis and peptic ulcer disease. Igaku Shoin Publishers, New York, N.Y.
215. Marshall, B. J., J. A. Armstrong, D. B. McGechie, and R. J. Glancy. 1985. Attempt to fulfill Koch's postulates for pyloric Campylobacter. Med. J. Aust. 142:436-439.
216. Marshall, B. J., and J. R. Warren. 1984. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet i:1311-1315.
217. Manch, F., G. Bode, H. Ditschuneit, and P. Malfertheiner. 1993. Demonstration of a phospholipid-rich zone in the human gastric epithelium damaged by Helicobacter pylori. Gastroenterology 105:1698-1704.
218. McNulty, C. M. A., and D. M. Watson. 1984. Spiral bacteria of the gastric antrum. Lancet i:1068-1069.
219. Megraud, F. 1995. Transmission of Helicobacter pylori: faecal-oral versus oral-oral route. Aliment. Pharmacol. Ther. 9(Suppl. 2):85-91.
220. Melchers, K., T. Weitzenegger, A. Buhmann, W. Steinhilber, G. Sachs, and K. P. Schafer. 1996. Cloning and membrane topology of a P-type ATPase from Helicobacter pylori. J. Biol. Chem. 271:446-457.
221. Mendall, M. A., P. M. Goggin, N. Molineaux, J. Levy, T. Toosy, D. Strachan, A. J. Camm, and T. C. Northfield. 1994. Relation of Helicobacter pylori infection and coronary heart disease. Br. Heart J. 71:437-439.
222. Mendall, M. A., P. M. Goggin, N. Molineaux, J. Levy, T. Toosy, D. Strachan, and T. C. Northfield. 1992. Childhood living conditions and Helicobacter pylori seropositivity in adult life. Lancet 339:896-897.
223. Mendz, G. L., B. P. Burns, and S. L. Hazell. 1995. Characterisation of glucose transport in Helicobacter pylori. Biochim. Biophys. Acta 1244:269-276.
224. Mendz, G. L., and S. L. Hazell. 1991. Evidence for a pentose phosphate pathway in Helicobaaer pylori. FEMS Microbiol. Lett. 84:331-336.
225. Mendz, G. L., and S. L. Hazell. 1995. Aminoacid utilization by Helicobacter pylori. Int. J. Biochem. Cell Biol. 27:1085-1093.
226. Mendz, G. L., and S. L. Hazell. 1996. The urea cycle of Helicobacter pylori. Microbiology 142:2959-2967.
227. Mendz, G. L., S. L. Hazell, and B. P. Burns. 1994. The Entner-Doudoroff pathway in Helicobacter pylori. Arch. Biochem. Biophys. 312:349-356.
228. Mendz, G. L., S. L. Hazell, and S. Srinivasan. 1995. Fumarate reductase: a target for therapeutic intervention against Helicobacter pylori. Arch. Biochem. Biophys. 321:153-159.
229. Micots, I., C. Augeron, C. L. Laboisse, F. Muzeau, and F. Megraud. 1993. Mucin exocytosis: a major target for Helicobacter pylori. J. Clin. Pathol. 46:241-245.
230. Miehlke, S., K. Kibler, J. G. Kim, N. Figura, S. M. Small, D. Y. Graham, and M. F. Go. 1996. Allelic variation in the cagA gene of Helicobacter pylori obtained from Korea compared to the United States. Am. J. Gastroenterol. 91:1322-1325.
231. Minnis, J. A., T. E. Taylor, J. E. Knesek, W. L. Peterson, and S. A. McIntire. 1995. Characterization of a 3.5-kbp plasmid from Helicobacter pylori. Plasmid 34:22-36.
232. Misiewicz, J. J., A. W. Harris, K. D. Bardhan, and H. Longworthy. 1996. One week low dose triple therapy for eradication of H. pylori. A large multicenter randomized trial. Gastroenterology 110:A198.
233. Mitchell, H. M., A. Lee, and J. Carrick. 1989. Increased incidence of Campylobacter pylori infection in gastroenterologists: further evidence to support person-to-person transmission. Scand. J. Gastroenterol. 24:396-400
234. Mobley, H. L., R. M. Garner, and P. Bauerfeind. 1995. Helicobacter pylori nickel-transport gene NixA: synthesis of catalytically active urease in Escherichia coli independent of growth conditions. Mol. Microbiol. 16:97-109.
235. Mobley, H. L., M. D. Island, and R. P. Hausinger. 1995. Molecular biology of microbial ureases. Microbiol. Rev. 59:451-480.
236. Molyneux, A. J., and M. D. Harris. 1993. Helicobacter pylori in gastric biopsies - should you trust the pathology report? J. R. Coll. Physicians London 27:119-120.
237. Moran, A. P. 1996. The role of lipopolysaccharide in helicobacter pylori pathogenesis. Aliment. Pharmacol. Ther. 10(Suppl. 1):39-50.
238. Morris, A., and G. Nicholson. 1987. Ingestion of Campylobacter pyloridis causes gastritis and raised gastric pH. Am. J. Gastroenterol. 82:192-199.
239. Morris, A., G. Nicholson, J. Zwi, and M. Vanderwee. 1989. Campylobacter pylori infection in Meckel's diverticula containing gastric mucosa. Gut 30: 1233-1235.
240. Moss, S. F., J. Calam, B. Agarwal, S. Wang, and P. R. Holt. 1996. Induction of gastric epithelial apoptosis by Helicobacter pylori. Gut 38:498-501.
241. 13C-bicarbonate in the assessment of gastric Helicobacter pylori urease activity. Am. J. Gastroenterol. 88:369-374.
242. Muotiala, A., I. M. Helander, L. Pyhala, T. U. Kosunen, and A. P. Moran. 1992. Low biological activity of Helicobacter pylori lipopolysaccharide. Infect. Immun. 60:1714-1716.
243. Nagata, K., H. Satoh, T. Iwahi, T. Shimoyama, and T. Tamura. 1993. Potent inhibitory action of the gastric proton pump inhibitor lansoprazole against urease activity of Helicobacter pylori: unique action selective for H. pylori cells. Antimicrob. Agents Chemother. 37:769-774.
244. Nagata, K., S. Tsukita, T. Tamura, and N. Sone. 1996. A cb-type cytochrome-c oxidase terminates the respiratory chain in Helicobacter pylori. Microbiology 142:1757-1763.
245. Nakao, M., M. Tada, K. Tsuchimori, and M. Uekata. 1995. Antibacterial properties of lansoprazole alone and in combination with antimicrobial agents against Helicobacter pylori. Eur. J. Clin. Microbiol. Infect. Dis. 14: 391-399.
246. Neugut, A. I., M. Hayek, and G. Howe. 1996. Epidemiology of gastric cancer. Semin. Oncol. 23:281-291.
247. Nightingale, S. L. 1996. Breath test for Helicobacter pylori collection kit approved. JAMA 276:1710.
248. NIH Consensus Conference. 1994. Helicobacter pylori in peptic ulcer disease. NIH Consensus Development Panel on Helicobacter pylori in peptic ulcer disease. JAMA 272:65-69.
249. Nilius, M., A. Strohle, G. Bode, and P. Malfertheiner. 1993. Coccoid like forms (clf) of Helicobacter pylori. Enzyme activity and antigenicity. Int. J. Med. Microbiol. Virol. Parasitol. Infect. Dis. 280:259-272.
250. Nomura, A., G. N. Stemmermann, P. H. Chyou, I. Kato, G. I. Perez-Perez, and M. J. Blaser. 1991. Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii. N. Engl. 3. Med. 325:1132-1136.
251. Odenbriet, S., B. Wieland, and R. Haas. 1996. Cloning and genetic characterization of Helicobacter pylori catalase and construction of a catalase-deficient mutant strain. J. Bacteriol. 178:6960-6967.
252. Oderda, G., D. Vaira, and J. Holton. 1989. Amoxicillin plus tinidazole for Campylobacter pylori gastritis in children: assessment by serum IgG antibody. Lancet 1:690-692.
253. Oliva, M. M., A. J. Lazenby, and J. A. Perman. 1993. Gastritis associated with Gastrospirillum hominis in children. Comparison with Helicobacter pylori and review of the literature. Mod. Pathol. 6:513-515.
254. Olson, C. and A. Edwards. 1995. Primary susceptibility of H. pylori to clarithromycin compared to metronidazole in patients with duodenal ulcers associated with H. pylori. Gastroenterology 90:1589.
255. O'Toole, P. W., M. Kostrzynska, and T. J. Trust. 1994. Non-motile mutants of Helicobacter pylori and Helicobacter mustelae defective in flagellar hook production. Mol. Microbiol. 14:691-703.
256. Ottlecz, A., J. J. Romero, S. L. HazelL, D. Y. Graham, and L. M. Lichtenberger. 1993. Phospholipase activity of Helicobacler pylori and its inhibition by bismuth salts. Dig. Dis. Sci. 38:2071-2080.
257. Papini, E., M. de Bernard, E. Milia, M. Bugnoli, M. Zerial, R. Rappuoli, and C. Montecucco. 1994. Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments. Proc. Natl. Acd. Sci. USA 91:9720-9724.
258. Parsonnet, J. 1995. The incidence of Helicobacter pylori infection. Aliment. Pharmacol. Ther. 9(Suppl. 2):45-51.
259. Parsonnet, J., M. J. Blaser, G. I. Perez-Perez, N. Hargrett-Bean, and R. V. Tauxe. 1992. Symptoms and risk factors of Helicobacter pylori infection in a cohort of epidemiologists. Gastroenterology 102:41-46.
260. Parsonnet, J., G. D. Friedman, D. P. Vandersteen, Y. Chang, J. H. Vogelman, N. Orentreich, and R. K. Sibley. 1991. Helicobacter pylori infection and the risk of gastric carcinoma. N. Engl. J. Med. 325:1127-1131.
261. Parsonnet, J., S. Hansen, L. Rodriguez, A. B. Gelb, R. A. Warnke, E. Jellum, N. Orentreich, J. H. Vogelman, and G. D. Friedman. 1994. Helicobacter pylori infection and gastric lymphoma. N. Engl. J. Med. 330:1267-1271.
262. Patchett, S., S. Beattie, E. Leen, C. Keane, and C. O'Morain. 1992. Helicobacter pylori and duodenal ulcer recurrence. Am. J. Gastroenterol. 87: 24-27.
263. Patel, P., M. A. Mendall, D. Carrington, D. P. Strachan, E. Leatham, N. Molineaux, J. Levy, C. Blakeston, C. A. Seymour, and A. J. Camm. 1995. Association of Helicobacter pylori and Chlamydia pneumoniae infections with coronary heart disease and cardiovascular risk factors. Br. Med. J. 311:711-714.
264. Patel, P., M. A. Mendall, S. Khulusi, N. Molineaux, J. Levy, J. D. Maxwell, and T. C. Northfield. 1994. Salivary antibodies to Helicobacter pylori: screening dyspeptic patients before endoscopy. Lancet 344:511-512.
265. Patel, P., M. A. Mendall, S. Khulusi, T. C. Northfield, and D. P. Strachan. 1994. Helicobacter pylori infection in childhood: risk factors and effect on growth. Br. Med. J. 309:1119-1123.
266. 14C-urea administration in Helicobacter pylori infection. Am. J. Gastroenterol. 89:734-738.
267. Peek, R. M., G. G. Miller, and M. J. Blaser. 1995. Reverse transcription-polymerase chain reaction (RT-PCR) for bacterial and host gene expression in human gastric mucosa, p. 163-172. In A. Lee and F. Megraud (ed.), Helicobacter pylori: techniques for clinical diagnosis and basic research. The W. B. Saunders Co., London, United Kingdom.
268. Peek, R. M., S. A. Thompson, J. C. Atherton, M. J. Blaser, and G. G. Miller. 1996. Expression of iceA, a novel ulcer-associated Helicobacter pylori gene, is induced by contact with gastric epithelial cells and is associated with enhanced mucosal IL-8. Gut 39:A71.
269. Peek, R. M., Jr., G. G. Miller, K. T. Tham, G. I. Perez-Perez, T. L. Cover, J. C. Atherton, G. D. Dunn, and M. J. Blaser. 1995. Detection of Helicobacter pylori gene expression in human gastric mucosa. J. Clin. Microbiol. 33:28-32.
270. Penston, J. G. 1994. Review article: Helicobacter pylori eradication - understandable caution but no excuse for inertia. Aliment. Pharmacol. Ther. 8:369-389.
271. + proportion of H. pylori infections. Gut 39:A83.
272. Perez-Perez, G. I., B. M. Dworkin, J. E. Chodos, and M. J. Blaser. 1988. Campylobacter pylori antibodies in humans. Ann. Intern. Med. 109:11-17.
273. Perez-Perez, G. I., C. B. Gower, and M. J. Blaser. 1994. Effects of cations on Helicobacter pylori urease activity, release, and stability. Infect. Immun. 62:299-302.
274. Perez-Perez, G. I., S. S. Witkin, M. D. Decker, and M. J. Blaser. 1991. Seroprevalence of Helicobacter pylori infection in couples. J. Clin. Microbiol. 29:642-644.
275. Peterson, W. L. 1991. Helicobacter pylori and peptic ulcer disease. N. Engl. J. Med. 324:1043-1048.
276. Peterson, W. L., A. A. Ciociola, D. L. Sykes, D. J. Mcsorley, D. D. Webb, L. Adams, M. Barreiro, R. Baum, W. Berry, C. Brayko, J. Breiter, K. Chang, A. Y. Chen, R. G. Cline, L. Cubeddu, S. Dutta, A. Ertan, J. J. Fromkes, R. Graham, T. P. Hughes, D. S. James, M. Kamionkowski, T. Kovacs, R. M. Kerr, and D. Kruss. 1996. Ranitidine bismuth citrate plus clarithromycm is effective for healing duodenal ulcers, eradicating H. pylori and reducing ulcer recurrence. Aliment. Pharmacol. Ther. 10:251-261.
277. Peterson, W. L., D. Y. Graham, B. Marshall, M. J. Blaser, R. M. Genta, P. D. Klein, C. W. Stratton, J. Drnec, P. Prokocimer, and N. Siepman. 1993. Clarithromycin as monotherapy for eradication of Helicobacter pylori: a randomized, double-blind trial. Am. J. Gastroenterol. 88:1860-1864.
278. 14C-urea breath test offers diagnosis of Helicobacter pylori in 10 minutes. Am. J. Gastroenterol. 91:233-238.
279. Phadnis, S. H., D. Ilver, L. Janzon, S. Nonnark, and T. U. Westblom. 1994. Pathological significance and molecular characterization of the vacuolating toxin gene of Helicobacter pylori. Infect. Immun. 62:1557-1565.
280. Phadnis, S. H., M. H. Parlow, M. Levy, D. Ilver, C. M. Caulkins, J. B. Connors, and B. E. Dunn. 1996. Surface localization of Helicobacter pylori urease and a heat shock protein homolog requires bacterial autolysis. Infect. Immun. 64:905-912.
281. Pilotto, A., M. Franceschi, G. Leandro, F. DiMario, G. Soffiati, M. Scagnelli, L. Bozzola, R. Fabrello, and G. Valerio. 1996. The clinical usefulness of serum pepsinogens, specific IgG anti-H. pylori antibodies and gastrin for monitoring Helicobacter pylori treatment in older people. J. Am. Geriatr. Soc. 44:665-670.
282. Piotrowski, J., E. Piotrowski, A. Slomiany, and B. L. Slomiany. 1995. Susceptibility of Helicobacter pylori to antimicrobial agents: effect of ebrotidine and ranitidine. J. Physiol. Pharmacol. 46:463-469.
283. Piotrowski, J., A. Slomiany, and B. L. Slomiany. 1995. Inhibition of Helicobacter pylori urease activity by ebrotidine. Biochem. Mol. Biol. Int. 37: 247-253.
284. Polish, L. B., J. M. Douglas, Jr., A. J. Davidson, G. I. Perez-Perez, and M. J. Blaser. 1991. Characterization of risk factors for Helicobacter pylori infection among men attending a sexually transmitted disease clinic: lack of evidence for sexual transmission. J. Clin. Microbiol. 29:2139-2143.
285. 280a. Queiroz, D. M., E. N. Mendes, and G. A. Rocha. 1987. Indicator medium for isolation of Campylobacter pylori. J. Clin. Microbiol. 25:2378-2379.
286. 14C-urea breath test for the detection of Helicobacter pylori. Am. J. Gastroenterol. 89:1027-1031.
287. Reddy, R., M. Osato, O. Gutierrez, J. G. Kim, and D. Y. Graham. 1996. Metronidazole resistance is high in Korea and Columbia and appears to be rapidly increasing in the US. Gastroenterology 10:A236.
288. 282a. Replogle, M. L., S. L. Glaser, R. A. Hiatt, and J. Parsonnet. 1995. Biologic sex as a risk factor for Helicobacter pylori infection in healthy young adults. Am. J. Epidemiol. 142:856-863.
289. Ricci, V., C. Ciacci, R. Zarrilli, P. Sommi, M. K. Tummuru, C. Del Vecchio Blanco, C. B. Bruni, T. L. Cover, M. J. Blaser, and M. Romano. 1996. Effect of Helicobacter pylori on gastric epithelial cell migration and proliferation in vitro: role of vacA and cagA. Infect. Immun. 64:2829-2833.
290. Ringner, M., P. Aleljung, and T. Wadstrom. 1993. Adherence of haemagglutinating Helicobacter pylori to five cell lines. Int. J. Med. Microbiol. Virol. Parasitol. Infect. Dis. 280:107-112.
291. Sadowski, D., H. Cohen, L. Laine, P. Greenberg, J. Goldstein, M. Mihalov, and A. F. Cutler. 1996. Evaluation of the Flexsure HP fingerprick blood test for detection of Helicobacter pylori infection. Gastroenterology 110:A246.
292. Salim, A. S. 1993. The relationship between Helicobacter pylori and oxygen-derived free radicals in the mechanism of duodenal ulceration. Intern. Med. 32:359-364.
293. Sandifer, Q. D., S. V. Lo, and G. Crompton. 1996. Association may not be causal. Br. Med. J. 213:251.
294. Schmitt, W. and R. Haas. 1994. Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein. Mol. Microbiol. 12:307-319.
295. Schuman, R., B. Rigas, A. Prada, and G. Minoli. 1995. Diagnosis of Helicobacter pylori infection by the Lara system - towards a simplified breath test. Gastroenterology 108:A215.
296. Sharma, S. A., M. K. Tummuru, G. G. Miller, and M. J. Blaser. 1995. Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro. Infect. Immun. 63:1681-1687.
297. Sherburne, R., and D. E. Taylor. 1995. Helicobacter pylori expresses a complex surface carbohydrate. Lewis X. Infect. Immun. 63:4564-4568.
298. Simoons-Smit, I. M., B. J. Appelmelk, T. Verboom, R. Negrini, J. L. Penner, G. O. Aspinall, A. P. Moran, F. F. She, B. S. Shi, W. Rudnica, A. Savio, and J. Degraaff. 1996. Typing of Helicobacter pylori with monoclonal antibodies against Lewis antigens in lipopolysaccharide. J. Clin. Microbiol. 34:2196-2200.
299. Simor, A. E., E. Lin, F. Saibil, L. Cohen, M. Louie, S. Pearen, and H. A. Donhofer. 1996. Evaluation of enzyme immunoassay for detection of salivary antibody to Helicobacter pylori. J. Clin. Microbiol. 34:550-553.
300. Smith, A. W., B. Chahal, and G. L. French. 1994. The human gastric pathogen Helicobacter pylori has a gene encoding an enzyme first classified as a mucinase in Vibrio cholerae. Mol. Microbiol. 13:153-160.
301. Smoot, D. T., H. L. Mobley, G. R. Chippendale, J. F. Lewison, and J. H. Resau. 1990. Helicobacter pylori urease activity is toxic to human gastric epithelial cells. Infect. Immun. 58:1992-1994.
302. Sobala, G. M., J. E. Crabtree, M. F. Dixon, C. J. Schorah, J. D. Taylor, B. J. Rathbone, R. V. Heatley, and A. T. Axon. 1991. Acute Helicobacter pylori infection: clinical features, local and systemic immune response, gastric mucosal histology, and gastric juice ascorbic acid concentrations. Gut 32: 1415-1418.
303. Sobhani, I., A. Bado, Y. Cherifi, L. Moizo, J. P. Laigneau, D. Pospai, M. Mignon, and M. J. Lewin. 1996. Helicobacter pylori stimulates gastric acid secretion via platelet activating factor. J. Physiol. Pharmacol. 47:177-185.
304. Sobhani, I., Y. Denizot, C. Vissuzaine, J. Vatier, J. Benveniste, M. J. Lewin, and M. Mignon. 1992. Significance and regulation of gastric secretion of platelet-activating factor (paf-acether) in man. Dig. Dis. Sci. 37:1583-1592.
305. Soll, A. H. 1996. Consensus conference. Medical treatment of peptic ulcer disease. JAMA 275:622-629.
306. Solnick, J. V., J. O'Rourke, A. Lee, B. J. Paster, F. E. Dewhirst, and L. S. Tompkins. 1993. An uncultured gastric spiral organism is a newly identified Helicobacter in humans. J. Infect. Dis. 168:379-385.
307. Spiegelhalder, C., B. Gerstenecker, A. Kersten, E. Schiltz, and M. Kist. 1993. Purification of Helicobacter pylori superoxide dismutase and cloning and sequencing of the gene. Infect. Immun. 61:5315-5325.
308. Stolte, M., E. Wellens, B. Bethke, M. Ritter, and H. Eidt. 1994. Helicobacter heilmannii (formerly Gastrospirillum hominis) gastritis: an infection transmitted by animals? Scand. J. Gastroenterol. 29:1061-1064.
309. Stubbs, J. B., and B. J. Marshall. 1993. Radiation dose estimates for the carbon-14-labeled urea breath test. J. Nucl. Med. 34:821-825.
310. Suerbaum, S., C. Josenhans, and A. Labigne. 1993. Cloning and genetic characterization of the Helicobacter pylori and Helicobacter mustelae flab flagellin genes and construction of H, pylori flaa-and flab-negative mutants by electroporation-mediated allelic exchange. J. Bacteriol. 175:3278-3288.
311. Suerbaum, S., A. Schmitz, C. Josenhans, and A. Labigne. 1994. Cloning, sequencing, and mutagenesis of the H. pylori flbA gene: a homolog of the IcrD/flbF/invA family of genes associated with motility and virulence. Am. J. Gastroenterol. 89:1331.
312. Suerbaum, S., J. M. Thiberge, I. Kansau, R. L. Ferrero, and A. Labigne. 1994. Helicobacter pylori hspA-hspB heat-shock gene cluster: nucleotide sequence, expression, putative function and immunogenicity. Mol. Microbiol. 14:959-974.
313. Sumii, M., K. Sumii, A. Tari, H. Kawaguchi, G. Yamamoto, Y. Takehara, Y. Fukino, T. Kamiyasu, M. Hamada, and T. Tsuda. 1994. Expression of antral gastrin and somatostatin mRNA in Helicobacter pylori-infected subjects. Am. J. Gastroenterol. 89:1515-1519.
314. Sung, J. J., S. C. Chung, T. K. Ling, M. Y. Yung, V. K. Leung, E. K. Ng, M. K. Li, A. F. Cheng, and A. K. Li. 1995. Antibacterial treatment of gastric ulcers associated with Helicobacter pylori. N. Engl. J. Med. 332:139-142.
315. Suzuki, M., M. Nakamura, M. Mori, S. Miura, M. Tsuchiya, and H. Ishii. 1995. Lansoprazole inhibits oxygen-derived free radical production from neutrophils activated by Helicobacter pylori. J. Clin. Gastroenterol. 20 (Suppl. 2):S93-S96.
316. 309a. Tabak, M., R Armon, I. Potasman, and I. Neeman. 1996. In vitro inhibition of Helicobacter pylori by extracts of thyme. J. Appl. Microbiol. 80:667-672.
317. Talley, N. J., A. R. Zinsmeister, A. Weaver, E. P. DiMagno, H. A. Carpenter, G. I. Perez-Perez, and M. J. Blaser. 1991. Gastric adenocarcinoma and Helicobacter pylori infection. J. Natl. Cancer Inst. 83:1734-1739.
318. Taylor, D. E., M. Eaton, N. Chang, and S. M. Salama. 1992. Construction of a Helicobacter pylori genome map and demonstration of diversity at the genome level. J. Bacteriol. 174:6800-6806.
319. Taylor, D. N. and J. Parsonnet. 1995. Epidemiology and natural history of H. pylori infections, p. 551-564. In M. J. Blaser, P. F. Smith, J. Ravdin, H. Greenberg, and R. L. Guerrant (ed.), Infections of the gastrointestinal tract. Raven Press, New York, N.Y.
320. Telford, J. L., P. Ghiara, M. Dell'Orco, M. Comanducci, D. Burroni, M. Bugnoli, M. F. Tecce, S. Censini, A. Covacci, and Z. Xiang. 1994. Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease. J. Exp. Med. 179:1653-1658.
321. Thomas, J. E., G. R. Gibson, M. K. Darboe, A. Dale, and L. T. Weaver. 1992. Isolation of Helicobacter pylori from human faeces. Lancet 340:1194-1195.
322. Tomb, J.-F., G. Sutton, A. Glodek, L. Zhou, O. White, T. Utterback, J. Kelley, J. Peterson, R. Fleischmann, C. Bult, M. Adams, J. Gocayne, R. Clayton, N. Akopyants, D. E. Berg, H. O. Smith, C. Fraser, and J. C. Venter. 1996. The complete DNA sequence of the Helicobacter pylori genome. Gut 39(Suppl. 2):A2.
323. Tsuda, M., M. Karita, M. G. Morshed, K. Okita, and T. Nakazawa. 1994. A urease-negative mutant of Helicobacter pylori constructed by allelic exchange mutagenesis lacks the ability to colonize the nude mouse stomach. Infect. Immun. 62:3586-3589.
324. Tucci, A., R. Corinaldesi, V. Stanghellini, G. F. Paparo, S. Gasperoni, G. Biasco, O. Varoli, M. Ricci-Maccarini, and L. Barbara. 1993. One-day therapy for treatment of Helicobacter pylori infection. Dig. Dis. Sci. 38: 1670-1673.
325. Tummuru, M. K., T. L. Cover, and M. J. Blaser. 1993. Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: evidence of linkage to cytotoxin production. Infect. Immun. 61:1799-1809.
326. Tummuru, M. K. R., S. A. Sharma, and M. J. Blaser. 1995. Helicobacter pylori picB, a homolog of the Bordetella pertussis toxin secretion protein, is required for induction of IL-8 in gastric epithelial cells. Mol. Microbiol. 18:867-876.
327. Tytgat, G. N. 1995. Endoscopic transmission of Helicobacter pylon. Aliment. Pharmacol. Ther. 9(Suppl. 2):105-10.
328. Unge, P. 1996. Review of Helicobacter pylori eradication regimens. Scand. J. Gastroenterol. 15(Suppl. 2):74-81.
329. Utrup, L. J., S. K. Tanaka, C. Olson, and D. Y. Graham. 1996. Clarithromycin susceptibility testing breakpoints for Helicobacter pylori. Gut 39 (Suppl. 2):A11-A12.
330. Valkonen, K. H., M. Ringner, A. Ljungh, and T. Wadstrom. 1993. High-affinity binding of laminin by Helicobacter pylori: evidence for a lectin-like interaction. FEMS Immunol. Med. Microbiol. 7:29-37.
331. Valle, J., K. Seppala, P. Sipponen, and T. Kosunen. 1991. Disappearance of gastritis after eradication of Helicobacler pylori. A morphometric study.
332. 13C-urea breath test to the detection of Helicobacter pylori gastritis in children. Pediatrics 90:608-611.
333. Vanderende, A., E. A. J. Rauws, M. Feller, C. J. J. Mulder, G. N. J. Tytgat, and J. Dankert. 1996. Heterogeneous Helicobacter pylori isolates from members of a family with a history of peptic ulcer disease. Gastroenterology 111:638-647.
334. van der Hulst, R. W. M., J. J. Keller, E. A. J. Rauws, and G. N. J. Tytgat. 1996. Treatment of Helicobacter pylori infection: a review of the world literature. Helicobacter 1:6-19.
335. van Zwet, A. A., J. C. Thijs, and B. de Graaf. 1995. Explanations for high rates of eradication with triple therapy using metronidazole in patients harboring metronidazole-resistant Helicobacter pylori strains. Antimicrob. Agents Chemother. 39:250-252.
336. Vasquez, A., Y. Valdez, R. H. Gilman, J. J. McDonald, T. U. Westblom, D. Berg, H. Mayta, and V. Gutierrez. 1996. Metronidazole and clarithromycin resistance in Helicobacter pylori determined by measuring mics of antimicrobial agents in color indicator egg yolk agar in a miniwell format. J. Clin. Microbiol. 34:1232-1234.
337. Veenendaal, R. A., A. T. Lichtendahl-Bernards, A. S. Pena, H. P. Endtz, C. P. van Boven, and C. B. Lamers. 1993. Effect of transport medium and transportation time on culture of Helicobacter pylori from gastric biopsy specimens. J. Clin. Pathol. 46:561-563.
338. Walt, R. P. 1996. Regression of MALT lymphoma and treatment for Helicobacter pylori. Lancet 348:1041-1042.
339. Warren, J. R., and B. J. Marshall. 1983. Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet i:1273-1275.
340. Weel, J. F. L., R. W. M. Vanderhulst, Y. Gerrits, G. N. J. Tytgat, A. Vanderende, and J. Dankert. 1996. Heterogeneity in susceptibility to metronidazole among Helicobacter pylori isolates from patients with gastritis or peptic ulcer disease. J. Clin. Microbiol. 34:2158-2162.
341. Weitkamp, J. H., G. I. Perez-Perez, G. Bode, P. Malfertheiner, and M. J. Blaser. 1993. Identification and characterization of Helicobacter pylori phospholipase C activity. Int. J. Med. Microbiol. Virol. Parasitol. Infect. Dis. 280:11-27.
342. Wilson, K. T., K. S. Ramanujam, H. L. T. Mobley, R. F. Musselman, S. P. James, and S. J. Meltzer. 1996. Helicobacter pylori stimulates inducible nitric oxide synthase expression and activity in a murine macrophage cell line. Gastroenterology 111:1524-1533.
343. Wirth, H. P., M. Yang, R. M. Peek, K. T. Tham, and M. J. Blaser. 1997. Helicobacter pylori Lewis expression is related to the host Lewis phenotype, abstr. 3, p. A-1. In Abstracts of the American Gastroenterological Association Annual Meeting.
344. Wirth, H. P., M. Q. Yang, M. Karita, and M. J. Blaser. 1996. Expression of the human cell surface glycoconjugates Lewis X and Lewis Y by Helicobacler pylori isolates is related to cagA status. Infect. Immun. 64:4598-4605.
345. Witteman, E. M., W. P. Hopman, M. C. Becx, R. W. de Koning, G. N. Tytgat, A. J. Janssen, and J. B. Jansen. 1993. Short report: smoking habits and the acquisition of metronidazole resistance in patients with Helicobacter pylori-related gastritis. Aliment. Pharmacol. Ther. 7:683-687.
346. Worst, D. J., B. R. Otto, and J. De Graaff. 1995. Iron-repressible outer membrane proteins of Helicobacter pylori involved in heme uptake. Infect. Immun. 63:4161-4165.
347. Worst, D. J., M. Sparrius, E. J. Kuipers, J. G. Kusters, and J. Degraaff. 1996. Human serum antibody response against iron-repressible outer membrane proteins of Helicobacter pylori. FEMS Microbiol. Lett. 144:29-32.
348. Wotherspoon, A. C., C. Doglioni, T. C. Diss, L. Pan, A. Moschini, M. De Boni, and P. G. Isaacson. 1993. Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet 342:575-577.
349. Wotherspoon, A. C., C. Ortiz-Hidalgo, M. R. Falzon, and P. G. Isaacson. 1991. Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet 338:1175-1176.
350. + excretion test: a new method for detection of Helicobacter pylori infection. J. Clin. Microbiol. 30:181-184.
351. Xiang, Z., M. Bugnoli, A. Ponzetto, A. Morgando, N. Figura, A. Covacci, R. Petracca, C. Pennatini, S. Censini, and D. Armellini. 1993. Detection in an enzyme immunoassay of an immune response to a recombinant fragment of the 128 kilodalton protein (cagA) of Helicobacter pylori. Eur. J. Clin. Microbiol. Infect. Dis. 12:739-745.
352. Yang, R., R. Hamamoto, and L. Laine. 1996. Randomized comparison of 1 week and 2 week bismuth subsalicylate based triple therapy for the treatment of H. pylori. Gastroenterology 110:A302.
353. Yasunaga, Y., Y. Shinomura, S. Kanayama, M. Yabu, T. Nakanishi, Y. Miyazaki, Y. Murayama, J. J. Bonilla-Palacios, and Y. Matsuzawa. 1994. Improved fold width and increased acid secretion after eradication of the organism in Helicobacter pylori associated enlarged fold gastritis. Gut 35: 1571-1574.
354. Yoshida, N., T. Yoshikawa, S. Iinuma, M. Arai, S. Takenaka, K. Sakamoto, T. Miyajima, Y. Nakamura, N. Yagi, Y. Naito, F. Mukai, and M. Kondo. 1996. Rebamipide protects against activation of neutrophils by Helicobacter pylori. Dig. Dis. Sci. 41:1139-1144.
355. Yousfi, M. M., R. Reddy, M. S. Osato, and D. Y. Graham. 1996. Culture of Helicobacter pylori: effect of preimmersion of biopsy forceps in formalin. Helicobacter 1:62-64.