High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: Implications for decreased Nrf2 signaling

Journal of Neurochemistry

Volumn 114, Issue 6, 2010, Pages 1581-1589

  Morrison, Christopher D ^a   Pistell, Paul J ^a   Ingram, Donald K ^a   Johnson, William D ^a   Liu, Ying ^a   Fernandez Kim, Sun Ok ^a   White, Christy L ^a   Purpera, Megan N ^a   Uranga, Romina M ^a   Bruce Keller, Annadora J ^a   Keller, Jeffrey N ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

aging; cognition; high fat; oxidative stress

Indexed keywords

GLUCOSE; LARD; TRANSCRIPTION FACTOR NRF2; FAT INTAKE; GLUCOSE BLOOD LEVEL; INSULIN; LEPTIN; NFE2L2 PROTEIN, MOUSE;

AGED; AGING; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; HIPPOCAMPUS; HOMEOSTASIS; INSULIN RESISTANCE; INTRACELLULAR SIGNALING; LIPID DIET; LIPID METABOLISM; MALE; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CARBONYLATION; PROTEIN FUNCTION; WEIGHT GAIN; ADMINISTRATION AND DOSAGE; ANIMAL; BLOOD; BODY WEIGHT; C57BL MOUSE; COGNITION DISORDERS; FAT INTAKE; MAZE TEST; METABOLISM; PHYSIOLOGY; PSYCHOLOGY; SIGNAL TRANSDUCTION;

MUS;

ADIPOSITY; AGING; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; COGNITION DISORDERS; DIETARY FATS; HIPPOCAMPUS; INSULIN; LEPTIN; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTEIN CARBONYLATION; SIGNAL TRANSDUCTION;

EID: 77956298342     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06865.x     Document Type: Article

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