메뉴 건너뛰기




Volumn 107, Issue 32, 2010, Pages 14205-14210

Inducible response required for repair of low-dose radiation damage in human fibroblasts

Author keywords

Double strand break repair; Inducible response; Low radiation doses

Indexed keywords

ATM PROTEIN; DOUBLE STRANDED DNA; HISTONE H2AX; HYDROGEN PEROXIDE; PROTEIN H2AX GAMMA; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; H2AFX PROTEIN, HUMAN; HISTONE; PROTEIN SERINE THREONINE KINASE; TUMOR SUPPRESSOR PROTEIN;

EID: 77956295399     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1002213107     Document Type: Article
Times cited : (128)

References (41)
  • 1
    • 35548978945 scopus 로고    scopus 로고
    • The impact of a negligent G2/M checkpoint on genomic instability and cancer induction
    • Löbrich M, Jeggo PA (2007) The impact of a negligent G2/M checkpoint on genomic instability and cancer induction. Nat Rev Cancer 7:861-869.
    • (2007) Nat Rev Cancer , vol.7 , pp. 861-869
    • Löbrich, M.1    Jeggo, P.A.2
  • 2
    • 0035289717 scopus 로고    scopus 로고
    • Chromosomal stability and the DNA double-stranded break connection
    • van Gent DC, Hoeijmakers JH, Kanaar R (2001) Chromosomal stability and the DNA double-stranded break connection. Nat Rev Genet 2:196-206.
    • (2001) Nat Rev Genet , vol.2 , pp. 196-206
    • Van Gent, D.C.1    Hoeijmakers, J.H.2    Kanaar, R.3
  • 3
    • 4143081306 scopus 로고    scopus 로고
    • Estimated radiation risks potentially associated with full-body CT screening
    • Brenner DJ, Elliston CD (2004) Estimated radiation risks potentially associated with full-body CT screening. Radiology 232:735-738.
    • (2004) Radiology , vol.232 , pp. 735-738
    • Brenner, D.J.1    Elliston, C.D.2
  • 5
    • 68449103051 scopus 로고    scopus 로고
    • DNA double-strand breaks and their repair in blood lymphocytes of patients undergoing angiographic procedures
    • Kuefner MA, et al. (2009) DNA double-strand breaks and their repair in blood lymphocytes of patients undergoing angiographic procedures. Invest Radiol 44:440-446.
    • (2009) Invest Radiol , vol.44 , pp. 440-446
    • Kuefner, M.A.1
  • 6
    • 33845606709 scopus 로고    scopus 로고
    • Leukocyte DNA damage after multi-detector row CT: A quantitative biomarker of low-level radiation exposure
    • Rothkamm K, Balroop S, Shekhdar J, Fernie P, Goh V (2007) Leukocyte DNA damage after multi-detector row CT: A quantitative biomarker of low-level radiation exposure. Radiology 242:244-251.
    • (2007) Radiology , vol.242 , pp. 244-251
    • Rothkamm, K.1    Balroop, S.2    Shekhdar, J.3    Fernie, P.4    Goh, V.5
  • 7
    • 36549007486 scopus 로고    scopus 로고
    • Computed tomography - An increasing source of radiation exposure
    • Brenner DJ, Hall EJ (2007) Computed tomography - An increasing source of radiation exposure. N Engl J Med 357:2277-2284.
    • (2007) N Engl J Med , vol.357 , pp. 2277-2284
    • Brenner, D.J.1    Hall, E.J.2
  • 8
    • 6344259975 scopus 로고    scopus 로고
    • Effect of recent changes in atomic bomb survivor dosimetry on cancer mortality risk estimates
    • Preston DL, et al. (2004) Effect of recent changes in atomic bomb survivor dosimetry on cancer mortality risk estimates. Radiat Res 162:377-389.
    • (2004) Radiat Res , vol.162 , pp. 377-389
    • Preston, D.L.1
  • 9
    • 0033864575 scopus 로고    scopus 로고
    • Radiation-related cancer risks at low doses among atomic bomb survivors
    • Pierce DA, Preston DL (2000) Radiation-related cancer risks at low doses among atomic bomb survivors. Radiat Res 154:178-186.
    • (2000) Radiat Res , vol.154 , pp. 178-186
    • Pierce, D.A.1    Preston, D.L.2
  • 10
    • 10744219719 scopus 로고    scopus 로고
    • Cancer risks attributable to low doses of ionizing radiation: Assessing what we really know
    • Brenner DJ, et al. (2003) Cancer risks attributable to low doses of ionizing radiation: Assessing what we really know. Proc Natl Acad Sci USA 100:13761-13766.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 13761-13766
    • Brenner, D.J.1
  • 11
    • 70450199858 scopus 로고    scopus 로고
    • Understanding and characterisation of the risks to human health from exposure to low levels of radiation
    • Goodhead DT (2009) Understanding and characterisation of the risks to human health from exposure to low levels of radiation. Radiat Prot Dosimetry 137:109-117.
    • (2009) Radiat Prot Dosimetry , vol.137 , pp. 109-117
    • Goodhead, D.T.1
  • 12
    • 77951298967 scopus 로고    scopus 로고
    • New radiobiological, radiation risk and radiation protection paradigms
    • Goodhead DT (2010) New radiobiological, radiation risk and radiation protection paradigms. Mutat Res 687:13-16.
    • (2010) Mutat Res , vol.687 , pp. 13-16
    • Goodhead, D.T.1
  • 13
    • 70350391647 scopus 로고    scopus 로고
    • Extrapolating radiation-induced cancer risks from low doses to very low doses
    • Brenner DJ (2009) Extrapolating radiation-induced cancer risks from low doses to very low doses. Health Phys 97:505-509.
    • (2009) Health Phys , vol.97 , pp. 505-509
    • Brenner, D.J.1
  • 14
    • 70350395466 scopus 로고    scopus 로고
    • Does scientific evidence support a change from the LNT model for low-dose radiation risk extrapolation?
    • Averbeck D (2009) Does scientific evidence support a change from the LNT model for low-dose radiation risk extrapolation? Health Phys 97:493-504.
    • (2009) Health Phys , vol.97 , pp. 493-504
    • Averbeck, D.1
  • 16
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou EP, Boon C, Redon C, Bonner WM (1999) Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 146:905-916.
    • (1999) J Cell Biol , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 17
    • 0034739853 scopus 로고    scopus 로고
    • P53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
    • Schultz LB, Chehab NH, Malikzay A, Halazonetis TD (2000) p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J Cell Biol 151:1381-1390.
    • (2000) J Cell Biol , vol.151 , pp. 1381-1390
    • Schultz, L.B.1    Chehab, N.H.2    Malikzay, A.3    Halazonetis, T.D.4
  • 18
    • 33646117239 scopus 로고    scopus 로고
    • Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
    • Bekker-Jensen S, et al. (2006) Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J Cell Biol 173:195-206.
    • (2006) J Cell Biol , vol.173 , pp. 195-206
    • Bekker-Jensen, S.1
  • 19
    • 76149146422 scopus 로고    scopus 로고
    • Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites
    • So S, Davis AJ, Chen DJ (2009) Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites. J Cell Biol 187:977-990.
    • (2009) J Cell Biol , vol.187 , pp. 977-990
    • So, S.1    Davis, A.J.2    Chen, D.J.3
  • 20
    • 1642556817 scopus 로고    scopus 로고
    • A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity
    • Kühne M, et al. (2004) A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity. Cancer Res 64:500-508.
    • (2004) Cancer Res , vol.64 , pp. 500-508
    • Kühne, M.1
  • 21
    • 9744220428 scopus 로고    scopus 로고
    • A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci
    • Riballo E, et al. (2004) A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. Mol Cell 16:715-724.
    • (2004) Mol Cell , vol.16 , pp. 715-724
    • Riballo, E.1
  • 22
    • 0036789173 scopus 로고    scopus 로고
    • Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody
    • Sedelnikova OA, Rogakou EP, Panyutin IG, Bonner WM (2002) Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody. Radiat Res 158:486-492.
    • (2002) Radiat Res , vol.158 , pp. 486-492
    • Sedelnikova, O.A.1    Rogakou, E.P.2    Panyutin, I.G.3    Bonner, W.M.4
  • 23
    • 67651162117 scopus 로고    scopus 로고
    • Cellular responses to DNA double-strand breaks after low-dose gamma-irradiation
    • Asaithamby A, Chen DJ (2009) Cellular responses to DNA double-strand breaks after low-dose gamma-irradiation. Nucleic Acids Res 37:3912-3923.
    • (2009) Nucleic Acids Res , vol.37 , pp. 3912-3923
    • Asaithamby, A.1    Chen, D.J.2
  • 24
    • 21144456719 scopus 로고    scopus 로고
    • In vivo formation and repair of DNA double-strand breaks after computed tomography examinations
    • Löbrich M, et al. (2005) In vivo formation and repair of DNA double-strand breaks after computed tomography examinations. Proc Natl Acad Sci USA 102:8984-8989.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8984-8989
    • Löbrich, M.1
  • 25
    • 0037884963 scopus 로고    scopus 로고
    • Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses
    • Rothkamm K, Löbrich M (2003) Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses. Proc Natl Acad Sci USA 100:5057-5062.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5057-5062
    • Rothkamm, K.1    Löbrich, M.2
  • 26
    • 71549139713 scopus 로고    scopus 로고
    • Inter-individual variation in DNA double-strand break repair in human fibroblasts before and after exposure to low doses of ionizing radiation
    • Wilson PF, et al. (2010) Inter-individual variation in DNA double-strand break repair in human fibroblasts before and after exposure to low doses of ionizing radiation. Mutat Res 683:91-97.
    • (2010) Mutat Res , vol.683 , pp. 91-97
    • Wilson, P.F.1
  • 27
    • 57149136324 scopus 로고    scopus 로고
    • GammaH2AX and cancer
    • Bonner WM, et al. (2008) GammaH2AX and cancer. Nat Rev Cancer 8:957-967.
    • (2008) Nat Rev Cancer , vol.8 , pp. 957-967
    • Bonner, W.M.1
  • 29
    • 0036023739 scopus 로고    scopus 로고
    • Modelling of DNA damage induced by energetic electrons (100 eV to 100 keV)
    • Nikjoo H, et al. (2002) Modelling of DNA damage induced by energetic electrons (100 eV to 100 keV). Radiat Prot Dosimetry 99:77-80.
    • (2002) Radiat Prot Dosimetry , vol.99 , pp. 77-80
    • Nikjoo, H.1
  • 30
    • 0018787368 scopus 로고
    • X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution
    • Bradley MO, Kohn KW (1979) X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution. Nucleic Acids Res 7:793-804.
    • (1979) Nucleic Acids Res , vol.7 , pp. 793-804
    • Bradley, M.O.1    Kohn, K.W.2
  • 31
    • 77953166592 scopus 로고    scopus 로고
    • GammaH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization
    • Löbrich M, et al. (2010) gammaH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization. Cell Cycle 9:662-669.
    • (2010) Cell Cycle , vol.9 , pp. 662-669
    • Löbrich, M.1
  • 32
    • 54049094397 scopus 로고    scopus 로고
    • Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
    • Chen Y, Chen PL, Chen CF, Jiang X, Riley DJ (2008) Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control. Cell Cycle 7:3194-3201.
    • (2008) Cell Cycle , vol.7 , pp. 3194-3201
    • Chen, Y.1    Chen, P.L.2    Chen, C.F.3    Jiang, X.4    Riley, D.J.5
  • 33
    • 10844257527 scopus 로고    scopus 로고
    • NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response
    • Polci R, Peng A, Chen PL, Riley DJ, Chen Y (2004) NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response. Cancer Res 64:8800-8803.
    • (2004) Cancer Res , vol.64 , pp. 8800-8803
    • Polci, R.1    Peng, A.2    Chen, P.L.3    Riley, D.J.4    Chen, Y.5
  • 34
    • 58149180926 scopus 로고    scopus 로고
    • DNA double-strand break repair of blood lymphocytes and normal tissues analysed in a preclinical mouse model: Implications for radiosensitivity testing
    • Rübe CE, et al. (2008) DNA double-strand break repair of blood lymphocytes and normal tissues analysed in a preclinical mouse model: Implications for radiosensitivity testing. Clin Cancer Res 14:6546-6555.
    • (2008) Clin Cancer Res , vol.14 , pp. 6546-6555
    • Rübe, C.E.1
  • 35
    • 26444485969 scopus 로고    scopus 로고
    • Biological effects in unirradiated human tissue induced by radiation damage up to 1 mm away
    • Belyakov OV, et al. (2005) Biological effects in unirradiated human tissue induced by radiation damage up to 1 mm away. Proc Natl Acad Sci USA 102:14203-14208.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 14203-14208
    • Belyakov, O.V.1
  • 36
    • 3142534591 scopus 로고    scopus 로고
    • Initiating cellular stress responses
    • Bakkenist CJ, Kastan MB (2004) Initiating cellular stress responses. Cell 118:9-17.
    • (2004) Cell , vol.118 , pp. 9-17
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 37
    • 65949112277 scopus 로고    scopus 로고
    • Oxidation status of human OGG1-S326C polymorphic variant determines cellular DNA repair capacity
    • Bravard A, et al. (2009) Oxidation status of human OGG1-S326C polymorphic variant determines cellular DNA repair capacity. Cancer Res 69:3642-3649.
    • (2009) Cancer Res , vol.69 , pp. 3642-3649
    • Bravard, A.1
  • 38
    • 33847050801 scopus 로고    scopus 로고
    • Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
    • Kensler TW, Wakabayashi N, Biswal S (2007) Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu Rev Pharmacol Toxicol 47:89-116.
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 89-116
    • Kensler, T.W.1    Wakabayashi, N.2    Biswal, S.3
  • 39
    • 74049120454 scopus 로고    scopus 로고
    • Nrf2: Friend or foe for chemoprevention?
    • Kensler TW, Wakabayashi N (2010) Nrf2: Friend or foe for chemoprevention? Carcinogenesis 31:90-99.
    • (2010) Carcinogenesis , vol.31 , pp. 90-99
    • Kensler, T.W.1    Wakabayashi, N.2
  • 40
    • 70350763838 scopus 로고    scopus 로고
    • ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
    • Beucher A, et al. (2009) ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2. EMBO J 28:3413-3427.
    • (2009) EMBO J , vol.28 , pp. 3413-3427
    • Beucher, A.1
  • 41
    • 33947204449 scopus 로고    scopus 로고
    • Chromosome breakage after G2 checkpoint release
    • Deckbar D, et al. (2007) Chromosome breakage after G2 checkpoint release. J Cell Biol 176:749-755.
    • (2007) J Cell Biol , vol.176 , pp. 749-755
    • Deckbar, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.