Sphingosine interaction with acidic leucine-rich nuclear phosphoprotein-32A (ANP32A) regulates PP2A activity and cyclooxygenase (COX)-2 expression in human endothelial cells

Journal of Biological Chemistry

Volumn 285, Issue 35, 2010, Pages 26825-26831

  Habrukowich, Cheryl ^b   Han, David K ^b   Le, Andrew ^b   Rezaul, Karim ^b   Pan, Wei ^c   Ghosh, Mallika ^b   Li, Zaiguo ^d   Dodge Kafka, Kimberly ^b   Jiang, Xuejun ^c   Bittman, Robert ^d   Hla, Timothy ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL FATES; CELLULAR SIGNALING; CELLULAR TARGETS; CYCLOOXYGENASES; ENZYME COMPLEXES; HUMAN ENDOTHELIAL CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; IN-VITRO; INFLAMMATORY GENES; MOLECULAR TARGETS; PHYTOSPHINGOSINES; PROTEIN PHOSPHATASE 2A; PROTEOMICS TECHNOLOGY; SPHINGOID BASIS; SPHINGOLIPIDS; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATES; SPHINGOSINE KINASE; STRESS-ACTIVATED PROTEIN KINASE;

AFFINITY CHROMATOGRAPHY; AMINO ACIDS; DIAMONDS; ENZYME INHIBITION; GENE EXPRESSION; MOLECULAR BIOLOGY; MOLECULAR PHYSICS; PHOSPHORYLATION; PROTEINS; SELF ASSEMBLY; SIGNALING;

ENDOTHELIAL CELLS;

ACIDIC LEUCINE RICH NUCLEAR PHOSPHOPROTEIN 32A; CYCLOOXYGENASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; N,N DIMETHYLSPHINGOSINE; PHOSPHOPROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2A; PHYTOSPHINGOSINE; RNA; SPHINGANINE; SPHINGOSINE; SPHINGOSINE KINASE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; PROTEOMICS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UMBILICAL VEIN;

CELL LINE; CYCLOOXYGENASE 2; ENDOTHELIAL CELLS; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE KINASE 4; PROTEIN PHOSPHATASE 2; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SPHINGOSINE;

SPHINGOIDEA;

EID: 77956259768     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.147058     Document Type: Article

References (36)

1. Bartke, N., and Hannun, Y. A. (2009) J. Lipid Res. 50, (suppl.) S91-S96
2. Hla, T., Lee, M. J., Ancellin, N., Paik, J. H., and Kluk, M. J. (2001) Science 294, 1875-1878
3. Spiegel, S., and Milstien, S. (2003) Nat. Rev. Mol. Cell Biol. 4, 397-407
4. Morales, A., Lee, H., Goñi, F. M., Kolesnick, R., and Fernandez-Checa, J. C. (2007) Apoptosis 12, 923-939
5. Cuvillier, O. (2002) Biochim. Biophys. Acta 1585, 153-162
6. Ohta, H., Sweeney, E. A., Masamune, A., Yatomi, Y., Hakomori, S., and Igarashi, Y. (1995) Cancer Res. 55, 691-697
7. Nava, V. E., Cuvillier, O., Edsall, L. C., Kimura, K., Milstien, S., Gelmann, E. P., and Spiegel, S. (2000) Cancer Res. 60, 4468-4474
8. Kohno, M., Momoi, M., Oo, M. L., Paik, J. H., Lee, Y. M., Venkataraman, K., Ai, Y., Ristimaki, A. P., Fyrst, H., Sano, H., Rosenberg, D., Saba, J. D., Proia, R. L., and Hla, T. (2006) Mol. Cell. Biol. 26, 7211-7223
9. Urs, A. N., Dammer, E., and Sewer, M. B. (2006) Endocrinology 147, 5249-5258
10. Ferguson-Yankey, S. R., Skrzypek, M. S., Lester, R. L., and Dickson, R. C. (2002) Yeast 19, 573-586
11. Zanolari, B., Friant, S., Funato, K., Sütterlin, C., Stevenson, B. J., and Riezman, H. (2000) EMBO J. 19, 2824-2833
12. Megidish, T., Cooper, J., Zhang, L., Fu, H., and Hakomori, S. (1998) J. Biol. Chem. 273, 21834-21845
13. Hla, T., and Neilson, K. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 7384-7388
14. Sadygov, R. G., Eng, J., Durr, E., Saraf, A., McDonald, H., MacCoss, M. J., and Yates, J. R., 3rd. (2002) J. Proteome Res. 1, 211-215
15. Han, D. K., Eng, J., Zhou, H., and Aebersold, R. (2001) Nat. Biotechnol. 19, 946-951
16. Frangioni, J. V., and Neel, B. G. (1993) J. Cell Sci. 105, 481-488
17. Arur, S., Uche, U. E., Rezaul, K., Fong, M., Scranton, V., Cowan, A. E., Mohler, W., and Han, D. K. (2003) Dev. Cell 4, 587-598
18. Ames, B. N., and Dubin, D. T. (1960) J. Biol. Chem. 235, 769-775
19. Li, M., Makkinje, A., and Damuni, Z. (1996) Biochemistry 35, 6998-7002
20. Ghosh, M., Wang, H., Ai, Y., Romeo, E., Luyendyk, J. P., Peters, J. M., Mackman, N., Dey, S. K., and Hla, T. (2007) J. Exp. Med. 204, 2053-2061
21. Brennan, C. M., Gallouzi, I. E., and Steitz, J. A. (2000) J. Cell Biol. 151, 1-14
22. Argraves, K. M., Obeid, L. M., and Hannun, Y. A. (2002) Adv. Exp. Med. Biol. 507, 439-444
23. Avdi, N. J., Malcolm, K. C., Nick, J. A., and Worthen, G. S. (2002) J. Biol. Chem. 277, 40687-40696
24. Dubois, R. N., Abramson, S. B., Crofford, L., Gupta, R. A., Simon, L. S., Van De Putte, L. B., and Lipsky, P. E. (1998) Faseb J. 12, 1063-1073
25. Lasa, M., Mahtani, K. R., Finch, A., Brewer, G., Saklatvala, J., and Clark, A. R. (2000) Mol. Cell. Biol. 20, 4265-4274
26. Ristimäki, A., Garfinkel, S., Wessendorf, J., Maciag, T., and Hla, T. (1994) J. Biol. Chem. 269, 11769-11775
27. Jiang, X., Kim, H. E., Shu, H., Zhao, Y., Zhang, H., Kofron, J., Donnelly, J., Burns, D., Ng, S. C., Rosenberg, S., and Wang, X. (2003) Science 299, 223-226
28. Pan, W., da Graca, L. S., Shao, Y., Yin, Q., Wu, H., and Jiang, X. (2009) J. Biol. Chem. 284, 6946-6954
29. Santa-Coloma, T. A. (2003) Cerebellum 2, 310-320
30. Huyton, T., and Wolberger, C. (2007) Protein Sci. 16, 1308-1315
31. Yoon, C. H., Kim, M. J., Park, M. T., Byun, J. Y., Choi, Y. H., Yoo, H. S., Lee, Y. M., Hyun, J. W., and Lee, S. J. (2009) Mol. Cancer Res. 7, 361-370
32. Ballou, L. R., Chao, C. P., Holness, M. A., Barker, S. C., and Raghow, R. (1992) J. Biol. Chem. 267, 20044-20050
33. Pettus, B. J., Bielawski, J., Porcelli, A. M., Reames, D. L., Johnson, K. R., Morrow, J., Chalfant, C. E., Obeid, L. M., and Hannun, Y. A. (2003) Faseb J. 17, 1411-1421
34. Skoura, A., Sanchez, T., Claffey, K., Mandala, S. M., Proia, R. L., and Hla, T. (2007) J. Clin. Invest. 117, 2506-2516
35. Lemonnier, L. A., Dillehay, D. L., Vespremi, M. J., Abrams, J., Brody, E., and Schmelz, E. M. (2003) Arch. Biochem. Biophys. 419, 129-138
36. Merrill, A. H., Jr., Schmelz, E. M., Wang, E., Dillehay, D. L., Rice, L. G., Meredith, F., and Riley, R. T. (1997) J. Nutr. 127, 830S-833S