Combination of photodynamic therapy with aspirin in human-derived lung adenocarcinoma cells affects proteasome activity and induces apoptosis

Cell Proliferation

Volumn 43, Issue 5, 2010, Pages 480-493

  Chiaviello, A ^a   Paciello, I ^a   Postiglione, I ^a   Crescenzi, E ^a   Palumbo, G ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CYCLIN DEPENDENT KINASE INHIBITOR 1B; I KAPPA B ALPHA; PROTEASOME; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PARAMETERS; CELL SURVIVAL; CELL VIABILITY; COLONY FORMATION; COLONY FORMING UNIT; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IRRADIATION; LUNG NON SMALL CELL CANCER; OXIDATIVE STRESS; PHOTODYNAMIC THERAPY; PROTEIN EXPRESSION; UBIQUITINATION; CARCINOMA, NON-SMALL-CELL LUNG; CELL CYCLE; DRUG EFFECTS; LUNG NEOPLASMS; METABOLISM; PHOTOCHEMOTHERAPY; PROCEDURES; TUMOR CELL LINE;

APOPTOSIS; ASPIRIN; CARCINOMA, NON-SMALL-CELL LUNG; CELL CYCLE; CELL LINE, TUMOR; HUMANS; LUNG NEOPLASMS; PHOTOCHEMOTHERAPY; PROTEASOME ENDOPEPTIDASE COMPLEX;

EID: 77956258093     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2010.00698.x     Document Type: Article

References (39)

1. Orlowski RZ (1999) The role of the ubiquitin-proteasome pathway in apoptosis. Cell Death Differ. 6, 303 313.
2. Adams J (2004) The proteasome: a suitable antineoplastic target. Nat. Rev. Cancer 4, 349 360.
3. Karin M, Yamamoto Y, Wang QM (2004) The IKK NF-kappaB system: a treasure trove for drug development. Nat. Rev. Drug Discov. 3, 17 26.
4. Fribley A, Zeng Q, Wang CY (2004) Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells. Mol. Cell. Biol. 24, 9695 9704.
5. Hershko A (1997) Roles of ubiquitin-mediated proteolysis in cell cycle control. Curr. Opin. Cell Biol. 9, 788 799.
6. Hideshima T, Bradner JE, Wong J, Chauhan D, Richardson P, Schreiber SL et al. (2005) Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumour activity in multiple myeloma. Proc. Natl. Acad. Sci. USA 10, 8567 8572.
7. Ling YH, Liebes L, Zou Y, Perez-Soler R (2003) Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells. J. Biol. Chem. 278, 33714 33723.
8. Naujokat C, Fuchs D, Berges C, Naujokat C, Fuchs D, Berges C (2007) Adaptive modification and flexibility of the proteasome system in response to proteasome inhibition. Biochim. Biophys. Acta 1773, 1389 1397.
9. Szokalska A, Makowski M, Nowis D, Wilczynski GM, Kujawa M, Wójcik C et al. (2009) Proteasome inhibition potentiates antitumor effects of photodynamic therapy in mice through induction of endoplasmic reticulum stress and unfolded protein response. Cancer Res. 69, 4235 4243.
10. Crescenzi E, Chiaviello A, Canti G, Reddi E, Veneziani BM, Palumbo G (2006) Low doses of cisplatin or gemcitabine plus Photofrin/photodynamic therapy: disjointed cell cycle phase-related activity accounts for synergistic outcome in metastatic non-small cell lung cancer cells (H1299). Mol. Cancer Ther. 5, 776 785.
11. Dikshit P, Chatterjee M, Goswami A, Mishra A, Jana NR (2006) Aspirin induces apoptosis through the inhibition of proteasome function. J. Biol. Chem. 281, 29228 29235.
12. Gauduchon J, Gouilleux F, Maillard S, Marsaud V, Renoir JM, Sola B (2005) 4-Hydroxytamoxifen inhibits proliferation of multiple myeloma cells in vitro through down-regulation of c-Myc, up-regulation of p27KIP1, and modulation of BCL-2 family members. Clin. Cancer Res. 11, 2345 2354.
13. Sun J, Wang L, Waring MA, Wang C, Woodman KK, Sheil AG (1997) Simple and reliable methods to assess hepatocyte viability in bioartificial liver support system matrices. Artif. Organs 21, 408 413.
14. Caro A, Puntarulo S (1986) Effect of in vivo iron supplementation on oxygen radical production by soybean roots. Biochim. Biophys. Acta 129, 245 251.
15. Bradford M (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248 254.
16. Laemmli UK (1971) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680 685.
17. Hsieh YJ, Wu CC, Chang CJ, Yu JS (2003) Subcellular localization of Photofrin determines the death phenotype of human epidermoid carcinoma A431 cells triggered by photodynamic therapy: when plasma membranes are the main targets. J. Cell. Physiol. 194, 363 375.
18. Ferrario A, Fisher AM, Rucker N, Gomer CJ (2005) Celecoxib and NS-398 enhance photodynamic therapy by increasing in vitro apoptosis and decreasing in vivo inflammatory and angiogenic factors. Cancer Res. 65, 9473 9478.
19. Usuda J, Chiu SM, Murphy ES, Lam M, Nieminen AL, Oleinick NL (2003) Domain-dependent photodamage to BCL-2. A membrane anchorage region is needed to form the target of phthalocyanine photosensitization. J. Biol. Chem. 278, 2021 2029.
20. Xue LY, Chiu SM, Oleinick NL (2001) Photochemical destruction of the BCL-2 oncoprotein during photodynamic therapy with the phthalocyanine photosensitizer Pc 4. Oncogene 20, 3420 3427.
21. Roninson IB, Broude EV, Chang BD (2001) If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumour cells. Drug Resist. Updat. 4, 303 313.
22. Lee DH, Goldberg AL (1998) Proteasome inhibitors: valuable new tools for cell biologists. Trends Cell. Biol. 8, 397 403.
23. Mailhes JB, Hilliard C, Loweryand M, London SL (2002) MG-132, an inhibitor of proteasomes and calpains, induced inhibition of oocyte maturation and aneuploidy in mouse oocytes. Cell Chromosome 1, 2.
24. Cusack JC (2003) Rationale for the treatment of solid tumours with the proteasome inhibitor bortezomib. Cancer Treat. Rev. 29, 21 31.
25. Dou QP, Nam S (2000) Pharmacological proteasome inhibitors and their therapeutic potential. Expert Opin. Ther. Pat. 10, 1263 1272.
26. Bazzaro M, Lee MK, Zoso A, Stirling WL, Santillan A, Shih IeM et al. (2006) Ubiquitin-proteasome system stress sensitizes ovarian cancer to proteasome inhibitor-induced apoptosis. Cancer Res. 66, 3754 3763.
27. Crescenzi E, Varriale L, Iovino M, Chiaviello A, Veneziani BM, Palumbo G (2004) Photodynamic therapy with indocyanine green complements and enhances low-dose cisplatin cytotoxicity in MCF-7 breast cancer cells. Mol. Cancer Ther. 3, 537 544.
28. Lu M, Strohecker A, Chen F, Kwan T, Bosman J, Jordan VC et al. (2008) Aspirin sensitizes cancer cells to TRAIL induced apoptosis by reducing survivin levels. Clin. Cancer Res. 14, 3168 3176.
29. Thoms HC, Dunlop MG, Stark LA (2007) p38-mediated inactivation of cyclin D1/cyclin-dependent kinase 4 stimulates nucleolar translocation of RelA and apoptosis in colorectal cancer cells. Cancer Res. 67, 1660 1669.
30. Yin MJ, Yamamoto Y, Gaynor RB (1998) The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature 396, 77 80.
31. Dolmans DE, Fukumura D, Jain RK (2003) Photodynamic therapy for cancer. Nat. Rev. Cancer 3, 380 387.
32. Dougherty TJ, Gomer CJ, Henderson BW (1998) Photodynamic therapy. J. Natl. Cancer Inst. 90, 889 905.
33. Dolmans DE, Kadambi A, Hill JS, Waters CA, Robinson BC, Walker JP et al. (2002) Vascular accumulation of a novel photosensitizer, MV6401, causes selective thrombosis in tumour vessels after photodynamic therapy. Cancer Res. 62, 2151 2156.
34. Fingar VH, Kik PK, Haydon PS, Cerrito PB, Tseng M, Abang E et al. (1999) Analysis of acute vascular damage after photodynamic therapy using benzoporphyrin derivative (BPD). Br. J. Cancer 79, 1702 1708.
35. Cantilena LR (1996) Clinical toxicology. The basic science of poisons In : Klaassen CD, ed. Casarett and Doull's Toxicology, pp 981 982. New York (NY, USA) : The McGraw-Hill Companies Inc.
36. Wu R, Lamontagne D, de Champlain J (2002) Antioxidative properties of acetylsalicylic acid on vascular tissues from normotensive and spontaneously hypertensive rats. Circulation 105, 387 392.
37. Podhaisky HP, Abate A, Polte T, Oberle S, Schröder H (1997) Aspirin protects endothelial cells from oxidative stress: possible synergism with vitamin E. FEBS Lett. 417, 349 351.
38. Ranchod TM, Guercio JR, Ying GS, Brucker AJ, Stoltz RA (2008) Effect of aspirin therapy on photodynamic therapy with verteporfin for choroidal neovascularization. Retina 28, 711 716.
39. Voorhees PM, Dees EC, O'Neil B, Orlowski RZ (2003) The proteasome as a target for cancer therapy. Clin. Cancer Res. 9, 6316 6325.