Regulation and function of potassium channels in aldosterone-sensitive distal nephron

Current Opinion in Nephrology and Hypertension

Volumn 19, Issue 5, 2010, Pages 463-470

  Wang, Wen Hui ^a   Yue, Peng ^a   Sun, Peng ^a   Lin, Dao Hong ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

big conductance K; c Src; renal outer medullary potassium channel; voltage gated K channel; with no lysine kinase

Indexed keywords

ALDOSTERONE; CALCIUM ACTIVATED BIG CONDUCTANCE POTASSIUM CHANNEL; CD63 ANTIGEN; CLATHRIN ADAPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOCHROME P450 EPOXYGENASE; ENZYME; INTERSECTIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR4.1; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR5.1; KLOTHO PROTEIN; PHOSPHOTRANSFERASE; PLENTY OF SH3; POTASSIUM; POTASSIUM CHANNEL; PROTEIN; PROTEIN KINASE C; PROTEIN KINASE WNK4; RENAL OUTER MEDULLARY POTASSIUM CHANNEL; SERUM GLUCOCORTICOIDS INDUCED KINASE 1; SODIUM; SRC FAMILY PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ALDOSTERONE SENSITIVE DISTAL NEPHRON; ENDOCYTOSIS; ION TRANSPORT; MOUSE; NEPHRON; NONHUMAN; POTASSIUM EXCRETION; PRIORITY JOURNAL; PROTEIN INTERACTION; REVIEW; TRANSGENIC ANIMAL;

ALDOSTERONE; ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GLUCURONIDASE; HUMANS; IMMEDIATE-EARLY PROTEINS; MAGNESIUM; NEPHRONS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; SRC-FAMILY KINASES;

EID: 77955921530     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/MNH.0b013e32833c34ec     Document Type: Review

References (80)

1. + secretion. Nat Genet 2003; 35:372-376.
2. Wei Y, Bloom P, Lin DH, et al. Effect of dietary K intake on the apical small-conductance K channel in the CCD: role of protein tyrosine kinase. Am J Physiol Renal Physiol 2001; 281:F206-F212.
3. Yoo D, Kim BY, CampoC, etal. Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A. J Biol Chem 2003; 278:23066-23075.
4. +-deprived mice. Am J Physiol Renal Physiol 2009; 297:F420-F428.
5. Grimm PR, Foutz RM, Brenner R, Sansom SC. Identification and localization of BK-beta subunits in the distal nephron of the mouse kidney. Am J Physiol Renal Physiol 2007; 293:F350-F359.
6. + conductance in principal cells of rat CCD. Am J Physiol Renal Physiol 2005; 288:F493-F504.
7. + channel in the basolateral membrane of mouse renal collecting duct principal cells. Am J Physiol Renal Physiol 2008; 294:F1398-F1407.
8. + channel at the basolateral membrane of the mouse distal convoluted tubles: similarities with Kir4-Kir5.1 heteromeric channels. J Physiol 2002; 538:391-404.
9. + channel at the basolateral membrane of the mouse distal convoluted tubule: similarities with Kir4-Kir5.1 heteromeric channels. J Physiol 2002; 538:391-404.
10. 2+-sensing receptor with the inwardly rectifying potassium channels Kir4.1 and Kir4.2 results in inhibition of channel function. Am J Physiol Renal Physiol 2007; 292: F1073-F1081.
11. Scholl UI, Choi M, Liu T, etal. Seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance (SeSAME syndrome) caused by muta tions in KCNJ10. Proc Natl Acad Sci USA 2009; 106:5842-5847.
12. Salkoff L, Butler A, FerreiraG, etal. High-conductance potassium channels of the SLO family. Nat Rev Neurosci 2006; 7:921-931.
13. Lu R, Alioua A, Kumar Y, et al. MaxiK channel partners: physiological impact. J Physiol 2006; 570:65-72.
14. -/~ mice is linked to deficient K secretion and aldosteronism. Proc Natl Acad Sci USA 2009; 106:11800-11805.
15. + conduction and selectivity. Science 1998; 280:69-77.
16. Welling PA, Ho K. A comprehensive guide to the ROMK potassium channel: form and function in health and disease. Am J Physiol Renal Physiol 2009; 297:F849-F863.
17. Wang W, Schwab A, Giebisch G. Regulation of small-conductance K channel in apical membrane of rat cortical collecting tubule. Am J Physiol 1990; 259:F494-F502.
18. Rapedius M, Haider S, Browner KF, etal. Structural and functional analysis of the putative pH sensor in the Kir1.1 (ROMK) potassium channel. EMBO Rep 2006; 7:611-616.
19. Sackin H, Syn S, Palmer LG, et al. Regulation of ROMK by extracellular cations. Biophys J 2001; 80:683-697.
20. +: mechanisms of coupling. J Gen Physiol 2004; 123:441-454.
21. Sackin H, Nanazashvili M, Palmer LG, etal. Structural locus of the pH Gate in the Kir1.1 inward rectifier channel. Biophys J 2005; 88:2597-2606.
22. Zhang Y-Y, Sackin H, Palmer LG. Localization of the pH gate in Kir1.1 channels. Biophys J 2006; 91:2901-2909.
23. Lu M, Leng Q, Egan ME, et al. CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney. J Clin Invest 2006; 116:797-806.
24. McNicholas CM, Nason MW, Guggino WB, et al. The functional CFTR-NBF1 is required for ROMK2-CFTR interaction. Am J Physiol 1997; 273:F843-F848.
25. Dong K, Xu J, Vanoye CG, et al. An amino acid triplet in the NH2 terminus of rat ROMK1 determines interaction with SUR2B. J Biol Chem 2001; 276: 44347-44353.
26. Lu M, Dong K, Egan ME, et al. Mouse cystic fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct. Proc Natl Acad Sci USA 2010; 107:6082-6087.
27. Palmer LG, Frindt G. High-conductance K channels in intercalated cells of the rat distal nephron. Am J Physiol Renal Physiology 2007; 292:F966-F973.
28. 2+-dependent big conductance K channels (BK) in cortical collecting duct. Proc Natl Acad Sci USA 2006; 103:19569-19574.
29. + regulates apical membrane expression of maxi-K channels in rabbit cortical collecting duct. Am J Physiol Renal Physiol 2005; 289:F922-F932.
30. Estilo G, Liu W, Pastor-Soler N, et al. Effect of aldosterone on BK channel expression in mammalian cortical collecting duct. Am J Physiol Renal Physiol 2008; 295:F780-F788.
31. + channels in apical membrane of rabbit connecting tubule. J Membr Biol 1998; 164:35-45.
32. + secretion in the cortical collecting duct is mediated by a maxi-K channel. Am J Physiol Renal Physiol 2001; 280:F786-F793.
33. Rieg T, Vallon V, Sausbier M, et al. The role of the BK channel in potassium homeostasis and flow-induced renal potassium excretion. Kidney Int 2007; 72:566-573.
34. BeckF-X, DorgeA, Giebisch G,Thurau K. Effect of diuretics on cell potassium transport: an electron microprobe study. Kidney Int 1990; 37:1423-1428.
35. Holtzclaw JD, Grimm PR, Sansom SC. Intercalated cell BK-{alpha}/{beta}4 channels modulate sodium and potassium handling during potassium adaptation. J Am Soc Nephrol 2010; 21:634-645.
36. Liu W, Wei Y, Sun P, et al. Mechanoregulation of BK channel activity in the mammalian cortical collecting duct: role of protein kinases A and C Am J Physiol Renal Physiol 2009; 297:F904-F915.
37. Palmer LG. Potassium secretion and the regulation of distal nephron K channels. Am J Physiol 1999; 277:F821-F825.
38. Frindt G, Palmer LG. Apical potassium channels in the rat connecting tubule. Am J Physiol Renal Physiol 2004; 287:F1030-F1037.
39. Ho K. The ROMK-cystic fibrosis transmembrane conductance regulator connection: new insights into the relationship between ROMK and cystic fibrosis transmembrane conductance regulator channels. Curr Opin Nephrol Hypertens 1998; 7:49-58.
40. + conductance in maturing rabbit principal cell. Am J Physiol 1997; 272:F397-F404.
41. Carrisoza R, Salvador C, Bobadilla N, et al. Expression and immunolocaliza-tion of ERG1 potassium channels in the rat kidney. HistochemCell Biol 2010; 133:189-199.
42. Zheng W, Verlander JW, Lynch IJ, et al. Cellular distribution of the potassium channel KCNQ1 in normal mouse kidney. Am J Physiol Renal Physiol 2007; 292:F456-F466.
43. Glaudemans B, Van Der Wijst J, Scola RH, et al. A missense mutation in the Kv1.1 voltage-gated potassium channel encoding gene KCNA1 is linked to human autosomal dominant hypomagnesemia. J Clin Invest 2009; 119:936-942.
44. + channel activity involves phosphorylation processes. Proc Natl Acad Sci\USA 1994; 91:8077-8081.
45. +channel, ROMK, by cyclic AMP-dependent protein kinase. J Biol Chem 1996; 271:9313-9319.
46. Ali S, Chen X, Lu M, et al. A kinase anchoring protein (AKAP) is required for mediating the effect of PKA on ROMK1. Proc Natl Acad Sci\USA 1998; 95:10274-10278.
47. Yoo D, Fang L, Mason A, et al. A phosphorylation-dependent export structure in ROMK (Kir 1.1) channel overrides an endoplasmic reticulum localization signal. J Biol Chem 2005; 280:35281-35289.
48. + channel (ROMK). Proc Natl Acad Sci USA 2005; 102:9954-9959.
49. Liou HH, Zhou SS, Huang CL. Regulation of ROMK1 channel by protein kinase A via a phosphatidylinositol 4,5-bisphosphate-dependent mechanism. Proc Natl Acad Sci USA 1999; 96:5820-5825.
50. Lin DH, Sterling H, Lerea KM, et al. Protein kinase C (PKC)-induced phosphorylation of ROMK1 is essential for the surface expression of ROMK1 channels. J Biol Chem 2002; 277:44332-44338.
51. Zhen WZ, Li XJ, Hilgemann DW, Huang CL. Protein kinase C inhibits ROMK1 channel activity via phosphotidylinositol-4,5-bisphosphosphate-dependent mechanism. J Biol Chem 2003; 276:16852-16856.
52. Lu M, Hebert SC, Giebisch G. Hydrolyzable ATP and PIP2 modulate the small-conductance K channel in apical membrane of rat cortical collecting duct. J Gen Physiol 2002; 120:603-615.
53. Huang C-L, Feng S, Hilgemann DW. Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gfty. Nature 1998; 391:803-806.
54. Kahle KT, Ring AM, Lifton RP. Molecular physiology of the WNK Kinases. Annu Rev Physiol 2008; 70:329-355.
55. + channel ROMK1 (Kir1.1). J Physiol 2006;571:275-286.
56. - flux in extrarenal epithelia. Proc Natl Acad Sci USA 2004; 101:2064-2069.
57. Cope G, Murthy M, Golbang AP, et al. WNK1 affects surface expression of the ROMK potassium channel independent of WNK4. J Am Soc Nephrol 2006; 17:1867-1874.
58. Lazrak A, Liu Z, Huang CL. Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms. Proc Natl Acad Sci\USA 2006; 103:161 5-1620.
59. Wade JB, Fang L, Liu J, et al. WNK1 kinase isoform switch regulates renal potassium excretion. Proc Natl Acad Sci USA 2006; 103:8558-8563.
60. + homeostasis. Proc Natl Acad Sci USA 2007; 104:4025-4029.
61. He G, Wang HR, Huang SK, Huang C-L. Intersectin links WNK kinase to endocytosis of ROMK1. J Clin Invest 2007; 117:1078-1087.
62. Fang L, Ganuti R, Kim BY, et al. The ARH adaptor protein regulates endocytosis of the ROMK potassium secretory channel in mouse kidney. J Clin Invest 2009; 119:3278-3289.
63. O'Reilly M, Marshall E, Speirs HJL, Brown RW. WNK1, a gene within a novel blood pressure control pathway, tissue-specifically generates radically different isoforms with and without a kinase domain. J Am Soc Nephrol 2003; 14:2447-2456.
64. Rozansky DJ, Cornwall T, Subramanya AR, et al. Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway. J Clin Invest 2009; 119:2601-2612.
65. Xu B, Stippec S, Lazrak A, et al. WNK1 activates SGK1 by a phosphatidylinositol 3-kinase-dependent and noncatalytic mechanism. J Biol Chem 2005; 280:34218-34223.
66. Vallon V, Wulff P, Huang DY, et al. Role of Sgk1 in salt and potassium homeostasis. Am J Physiol Regul Integr Comp Physiol 2005; 288:R4-R10.
67. Verrey F, Summa V, Heitzmann D, et al. Short-term aldosterone Action on Na,K-ATPase surface expression: role of aldosterone-induced SGK1? Ann NY Acad Sci 2003; 986:554-561.
68. +elimination in the sgk1-knockout mouse. J Am Soc Nephrol 2004; 15:885-891.
69. Lin DH, Sterling H, Lerea KM, etal. Kdepletion increases the protein tyrosine-mediated phosphorylation of ROMK. Am J Physiol Renal Physiol 2002; 283:F671-F677.
70. Yue P, Lin DH, Pan CY, et al. Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels. Proc Natl Acad Sci USA 2009; 106:15061-15066.
71. Palmer LG, Antonian L, Frindt G. Regulation of apical K and Na channels and Na/K pumps in rat cortical collecting tubule by dietary K. J Gen Physiol 1994; 104:693-710.
72. Saikaley A, Bichet D, Kucharczyk J, Peterson LN. Neuroendocrine factors mediating polydipsia induced by dietary Na, Cl, and K depletion. Am J Physiol Regul Integr Comp Physiol 1986; 251:R1071-R1077.
73. Ray PE, Suga SI, Liu XH, et al. Chronic potassium depletion induces renal injury, salt sensitivity, and hypertension in young rats. Kidney Int 2001; 59:1850-1858.
74. Sealey JE, Clark I, Bull MB, Laragh JH. Potassium balance and the control of renin secretion. J Clin Invest 1970; 49:2119-2127.
75. Wang T, Giebisch G. Effects of angiotensin II on electrolyte transport in the early and late distal tubule in rat kidney. Am J Physiol 1996; 271:F1 43-F149.
76. Wei Y, Zavilowitz B, Satlin LM, Wang WH. Angiotensin II inhibits the ROMK-like small-conductance K channel in renal cortical collecting duct during dietary K restriction. J Biol Chem 2007; 282:6455-6462.
77. + excretion by Klotho. Mol Pharmacol 2009; 76:38-46.
78. Lin D, Kamsteeg EJ, Zhang Y, et al. Expression of tetraspan protein CD63 activates protein-tyrosine kinase (PTK) and enhances the PTK-induced inhibition of ROMK channels. J Biol Chem 2008; 283:7674-7681.
79. Lin DH, Yue P, Pan CY, et al. stimulates the ubiquitination and the clathrin-independent endocytosis of ROMK1 channels. J Biol Chem 2009; 284: 29614-29624.
80. 2+-dependent bid conductance K channel in the cortical collecting duct. J Am Soc Nephrol 2009; 20:513-523.