Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway

Journal of Clinical Investigation

Volumn 119, Issue 9, 2009, Pages 2601-2612

  Rozansky, David J ^a,g   Cornwall, Tonya ^a   Subramanya, Arohan R ^b,c   Rogers, Shaunessy ^b   Yang, Yong Feng ^a   David, Larry L ^d   Zhu, Xiaoman ^b   Yang, Chao Ling ^b   Ellison, David H ^b,e,f  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^f PORTLAND VA MEDICAL CENTER   (United States)

^g NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ANGIOTENSIN; ASPARTIC ACID; EPITHELIAL SODIUM CHANNEL; PROTEIN KINASE WNK4; RENIN; SERINE; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SODIUM CHLORIDE COTRANSPORTER; THIAZIDE DIURETIC AGENT;

ALDOSTERONE RELEASE; ANIMAL CELL; ARTICLE; CONSENSUS SEQUENCE; CONTROLLED STUDY; GENE MUTATION; KIDNEY EPITHELIUM; KIDNEY TUBULE ABSORPTION; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SODIUM TRANSPORT; XENOPUS;

ALDOSTERONE; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; FEMALE; HUMANS; IMMEDIATE-EARLY PROTEINS; MICE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, DRUG; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SODIUM; SODIUM CHLORIDE SYMPORTERS; SYMPORTERS; XENOPUS LAEVIS;

EID: 70349216516     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI38323     Document Type: Article

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