Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 35, 2009, Pages 15061-15066

  Yue, Peng ^a   Lin, Dao Hong ^a   Pan, Chun Yang ^a   Leng, Qiang ^b   Giebisch, Gerhard ^b   Lifton, Richard P ^b   Wang, Wen Hui ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Collecting duct; Hyperkalemia; K secretion; Kir1.1

Indexed keywords

ALANINE; ASPARTIC ACID; POTASSIUM; POTASSIUM CHANNEL; PROTEIN KINASE WNK4; PROTEIN TYROSINE KINASE; RENAL OUTER MEDULLARY POTASSIUM CHANNEL; SERINE; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; STEROID RECEPTOR COACTIVATOR 1; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

CELL LINE; ELECTROPHYSIOLOGICAL PHENOMENA; HUMANS; IMMEDIATE-EARLY PROTEINS; PATCH-CLAMP TECHNIQUES; PHOSPHOSERINE; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; SRC-FAMILY KINASES;

EID: 70349279991     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0907855106     Document Type: Article

References (38)

1. Subramanya AR, Yang CL, McCormick JA, Ellison DH (2006) WNK kinases regulate sodium chloride and potassium transport by the aldosterone-sensitive distal nephron. Kidney Int 70:630-634.
2. Kahle KT, Ring AM, Lifton RP (2008) Mol Physiology of the WNK Kinases. Ann Rev Physiol 70:329-355.
3. Palmer LG (1999) Potassium secretion and the regulation of distal nephron K channels. Am J Physiol 277:F821-F825. (Pubitemid 30046055)
4. Giebisch G (1998) Renal potassium transport: Mechanisms and regulation. Am J Physiol Renal Physiol 274:F817-F833. (Pubitemid 28255859)
5. Frindt G, Palmer LG (1989) Low-conductance K channels in apical membrane of rat cortical collecting tubule. Am J Physiol 256:F143-F151. (Pubitemid 19049872)
6. Frindt G, Palmer LG (2004) Apical potassium channels in the rat connecting tubule. Am J Physiol Renal Physiol 287:F1030-F1037. (Pubitemid 39391100)
7. Frindt G, Palmer LG (1987) Ca-activated K channels in apical membrane of mammalian CCT, and their role in K secretion. Am J Physiol 252:F458-F467. (Pubitemid 17061772)
8. Ho K (1998) The ROMK-cystic fibrosis transmembrane conductance regulator connection: New insights into the relationship between ROMK and cystic fibrosis transmembrane conductance regulator channels. Curr Opin Nephrol Hypertens 7:49-58.
9. + conductance in maturing rabbit principal cell. Am J Physiol 272:F397-F404.
10. + secretion in the cortical collecting duct is mediated by a maxi-K channel. Am J Physiol Renal Physiol 280:F786-F793.
11. Satlin LM (2004) Developmental regulation of expression of renal potassium secretory channels. Curr Opin Nephrol Hypertens 13:445-450. (Pubitemid 38901624)
12. Bailey MA, et al. (2006) Maxi-K channels contribute to urinary potassium excretion in the ROMK-deficient mouse model of type II Bartter's syndrome and in adaptation to a high K diet. Kidney Int 70:51-59.
13. + secretion. Nat Genet 35:372-376.
14. Ring AM, et al. (2007) An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis. Proc Natl Acad Sci USA 104:4025-4029.
15. Frindt G, Shah A, Edvinsson J, Palmer LG (2009) Dietary K regulates ROMK channels in connecting tubule and cortical collecting duct of rat kidney. Am J Physiol Renal Physiol 296:F347-F354.
16. Palmer LG, Frindt G (1999) Regulation of apical K channels in rat cortical collecting tubule during changes in dietary K intake. Am J Physiol 277:F805-F812.
17. Wang W, Schwab A, Giebisch G (1990) Regulation of small-conductance K channel in apical membrane of rat cortical collecting tubule. Am J Physiol 259:F494-F502. (Pubitemid 20310459)
18. Bhargava A, et al. (2001) The serum- and glucocorticoid-induced kinase is a physiological mediator of aldosterone action. Endocrinology 142:1587-1594. (Pubitemid 32299688)
19. Palmer LG, Frindt G (1992) Regulation of apical membrane Na and K channels in rat renal collecting tubules by aldosterone. Seminars Nephrol 12:37-43.
20. Palmer LG, Antonian L, Frindt G (1994) Regulation of apical K and Na channels and Na/K pumps in rat cortical collecting tubule by dietary K. J Gen Physiol 104:693-710. (Pubitemid 24328598)
21. Wang WH (2004) Regulation of renal K transport by dietary K intake. Annu Rev Physiol 66:547-569.
22. Wang W, Lerea KM, Chan M, Giebisch G (2000) Protein tyrosine kinase regulates the number of renal secretory K channels. Am J Physiol Renal Physiol 278:F165-F171. (Pubitemid 30106138)
23. Moral Z, et al. (2001) Regulation of ROMK1 channels by protein-tyrosine kinase and -tyrosine phosphatase. J Biol Chem 276:7156-7163. (Pubitemid 37392017)
24. Lin DH, et al. (2002) K depletion increases the protein tyrosine-mediated phosphorylation of ROMK. Am J Physiol Renal Physiol 283:F671-F677. (Pubitemid 35033954)
25. Hebert SC, Desir G, Giebisch G, Wang W (2005) Molecular diversity and regulation of renal potassium channels. Physiol Rev 85:319-371. (Pubitemid 40173996)
26. Yoo D, et al. (2003) Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A. J Biol Chem 278:23066-23075. (Pubitemid 36830372)
27. Lin DH, et al. (2004) Protein tyrosine kinase is expressed and regulates ROMK1 location in the cortical collecting duct. Am J Physiol Renal Physiol 286:F881-F892.
28. Wei Y, Bloom P, Lin DH, Gu RM, Wang WH (2001) Effect of dietary K intake on the apical small-conductance K channel in the CCD: Role of protein tyrosine kinase. Am J Physiol Renal Physiol 281:F206-F212. (Pubitemid 32751339)
29. He G, Wang HR, Huang SK, Huang C-L (2007) Intersectin links WNK kinase to endocytosis of ROMK1. J Clin Invest 117:1078-1087. (Pubitemid 46556764)
30. O'Connell AD, et al. (2005) Phosphorylation-regulated endoplasmic reticulum retention signal in the renal outer-medullary K+ channel (ROMK). Proc Natl Acad Sci USA 102:9954-9959. (Pubitemid 40993674)
31. Ho K, et al. (1993) Cloning and expression of an inwardly rectifying ATP-regulated potassium channel. Nature 362:31-38. (Pubitemid 23087286)
32. Ohtsu H, et al. (2006) Angiotensin II signal transduction through small GTP-binding proteins: Mechanism and significance in vascular smooth muscle cells. Hypertension 48:534-540. (Pubitemid 44843847)
33. Palmer LG, Antonian L, Frindt G (1993) Regulation the the Na-K pump of the rat cortical collecting tubule by aldosterone. J Gen Physiol 102:43-57. (Pubitemid 23210592)
34. Rossier BC, Canessa CM, Schild L, Horisberger J-D (1994) Epithelial sodium channels. Curr Opin Nephrol Hypertens 3:487-496.
35. Cope G, et al. (2006) WNK1 affects surface expression of the ROMK potassium channel independent of WNK4. J Am Soc Nephrol 17:1867-1874. (Pubitemid 44036171)
36. O'Reilly M, Marshall E, Speirs HJL, Brown RW(2003) WNK1, a gene within a novel blood pressure control pathway, tissue-specifically generates radically different isoforms with and without a kinase domain. J Am Soc Nephrol 14:2447-2456. (Pubitemid 37169330)
37. Wade JB, et al. (2006) WNK1 kinase isoform switch regulates renal potassium excretion. Proc Natl Acad Sci USA 103:8558-8563.
38. Lazrak A, Liu Z, Huang CL (2006) Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms. Proc Natl Acad Sci USA 103:1615-1620. (Pubitemid 43191213)