The surrogate light chain in mouse B-cell development

International Reviews of Immunology

Volumn 13, Issue 4, 1996, Pages 341-356

  Rolink, Antonius ^a   Haasner, Dirk ^a   Melchers, Fritz ^a   Andersson, Jan ^a  

^a BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0030513489     PISSN: 08830185     EISSN: None     Source Type: Journal    
DOI: 10.3109/08830189609061757     Document Type: Article

References (41)

1. Rolink, A., Kudo, A., Karasuyama, H., Kikuchi, Y., and Melchers, F. Long-term proliferating early preB cell lines and clones with the potential to develop to surface-Ig positive mitogen-reactive B cells "in vitro" and "in vivo". EMBO J. 10, 327-336, 1991.
2. Relink, A., Grawunder, U., Winkler, T. H., Karasuyama, H., and Melchers, F. IL-2 receptor ot chain (CD25, TAC) expression defines a crucial stage in preB cell development. Int. Immunol. 6, 1257-1264, 1994.
3. Relink, A., Haasner, D., Nishikawa, S. I., and Melchers, F Changes in frequencies of clonable preB cells during life in different lymphoid organs of mice. Blood 81, 2290-2300, 1993
4. Ten Boekel, E., Melchers, F., and Rolink, A. The status of Ig loci rearrangements in single cells from different stages of B cell development. Int. Immunol. 7, 1013-1019, 1995.
5. Winkler, T. H., Rolink, A. G., Melchers, F., and Karasuyama, H. Precursor B cells of mouse bone marrow express two different complexes with the surrogate light chain on the surface. Eur. J. Immunol. 25, 446-450, 1995.
6. Mombaerts, P., Iacomini, J., Johnson, R. S., Herrup, K., Tonegawa, S., and Papaioannou, V. E. RAG-1-deficient mice have no mature B and T lymphocytes. Cell 68, 869-877, 1992.
7. Shinkai, Y., Rathbun, G., Lam, K. P., Oltz, E. M., Stewart, V., Mendelsohn, M , Charron, J., Datta, M., Young, F., Stall, A. M., and Alt, F. W. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 68, 855-867, 1992.
8. Karasuyama, H., Rolink, A., and Melchers, F. Recombinant interleukin 2 or 5, but not 3 or 4, induces maturation of resting mouse B lymphocytes and propagates proliferation of activated B cell blasts. J. Exp. Med. 167, 1377-1390, 1988.
9. Melchers, F., Karasuyama, H., Haasner, D., Bauer, S., Kudo, A., Sakaguchi, N., Jameson, B., and Rolink, A. The surrogate light chain in B-cell development. Immunol. Today 14, 60-68, 1993.
10. 5, a new light-chain-related locus selectively expressed in preB lymphocytes. Nature 324, 579-582, 1986.
11. 5 locus of the mouse, which appears to be selectively expressed in preB lymphocytes. EMBO J. 6, 2267-2272, 1987.
12. 5 gene on chromsome 16. Genomics 1, 277-279, 1987.
13. 5 gene transcribed selectively in pre-B lymphocytes. EMBO J. 6, 103-107, 1987.
14. 5 surrogate light chain in early bone marrow precursor B cells of normal and B-cell deficient mutant mice. Cell 77, 133-143, 1994.
15. μ protein) in murine pre-B cells is differently regulated from that of the intact μ, chain. Eur. J. Immunol. 21, 1359-1363, 1991.
16. 5 in B cell development. Cell 69, 823-831, 1992.
17. 5 gene. Eur. J. Immunol. 23, 1284-1288, 1993.
18. Kaartinen, M. and Mäkelä, O. Reading of D genes in variable frames as a source of antibody diversity. Imm. Today 6, 324-330, 1985.
19. H joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation. EMBO J. 9, 2133-2140, 1990.
20. Haasner, D., Rolink, A., and Melchers, F. Influence of surrogate L chain on DHJH-reading frame 2 suppression in mouse precursor B cells. Int. Immunology 6, 21-30, 1994.
21. Grawunder, U., Haasner, D., Melchers, F., and Rolink, A. Rearrangement and expression of κ light chain genes can occur without μ, heavy chain expression during differentiation of pre-B cells. Int. Immunol. 5, 1609-1618, 1993.
22. Kubagawa, H., Cooper, M. D., Carroll, A. J., and Burrows, P. D. Light-chain gene expression before heavychain gene rearrangement in preB cells transformed by Epstein-Barr virus. Proc. Natl. Acad. Sci. USA 86, 2356-2360, 1989.
23. Blackwell, T. K., Malynn, B. A., Pollock, R. R., Ferner, P., Covey, L. R., Fulop, G. M., Phillips, R. A., Yancopoulos, G. D., and Alt, F. Isolation of scid preB cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joins. EMBO J. 8, 735-742, 1989.
24. Milstein, C., Even, J., and Jarvis, J. M. Non-random features of the repertoire expressed by the members of one Vκ gene family and of the V-J recombination. Eur. J. Immunol. 22, 1627-1634, 1992.
25. Strasser, A., Wittingham, S., Vaux, D. L., Bath, M. L., Adams, J. M., Cory, S., and Harris, A. W. Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease. Proc. Natl. Acad. Sci. USA 88, 8661-8665, 1991.
26. Nuñiez, G., Hockenbery, D., McDonnell, T. J., Sorensen, C. M., and Korsmeyer, S. J. Bcl-2 maintains B cell memory. Nature 353, 71-73, 1991.
27. Storb, U., Denis, K. A , Brinster, R. L., and Witte, O. N. Pre-B cells in κ-transgenic mice. Nature (Lond.) 316, 356, 1985.
28. Grandien, A., Coutinho, A., and Anderson, J. Selective peripheral expansion and activation of B cells expressing endogeneous immunoglobulin in mu-transgenic mice. Eur. J. Immunol. 20, 991-998, 1990.
29. Iacomini, J. and Imanishi-Kan, T. The effect of an immunoglobulin μ transgene on B cell maturation. Eur. J. Immunol. 22, 745-751, 1992.
30. Nemazee, D. and Bürki, K. Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras. Proc. Natl. Acad. Sci. USA 86, 8039-8043, 1989.
31. Radic, M. Z., Erikson, J., Litwin, S., and Weigert. M. B lymphocytes may escape tolerance by revising their antigen receptors. J. Exp. Med. 177, 1165-1173, 1993.
32. Goodnow, C. C., Crosbie, J., Jorgensen, H., Brink. R. A., and Basten, A. Induction of self-tolerance in mature peripheral B lymphocytes. Nature 342, 385-391, 1989.
33. Bogen, B. and Weiss, S. A rearranged λ2 light gene chain retards but does not exclude κ and λ1 expression. Eur. J. Immunol. 21, 2391-2395, 1991.
34. Rusconi, S. and Köhler, G. Transmission and expression of a specific pair of rearranged immunoglobulin μ and κ genes in a transgenic mouse line. Nature 314, 330-338, 1985.
35. Spanopoulou, E., Roman, C. A. J., Corcoran, L. M., Schlissel, M. S., Silver, D. P., Nemazee, D., Nussenzweig, M. C , Shinton, S. A., Hardy. R. R., and Baltimore, D. Functional immunoglobulin transgenes guide ordered B-cell differentiation in RAG-1-deficient mice. Genes Dev. 8, 1030-1042, 1994.
36. Young, F., Ardman, B., Shinkai, Y., Lansford, R., Blackwell, T. K., Mendelsohn, M., Rolink, A., Melchers, F., and Alt, F. W Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation. Genes Dev. 8, 1043-1057, 1994.
37. Andersson, J., Melchers, F., and Rolink, A. Stimulation by T cell independent antigens can relieve the arrest of differentiation of immature auto-reactive B cells in the bone marrow. Scand. J. Immunol. 42, 21-33, 1995.
38. Melchers, F., Rolink, A., Grawunder, U., Winkler, T. H., Karasuyama, H., Ghia, P., and Andersson, J. Positive and negative selection events during B lymphopoiesis. Curr. Opin. Immunol. 7, 214-227, 1995.
39. Zöller, M. and Achtnich, M. Evidence for regulation of naturally activated autoreactive B cells. Eur. J. Immunol. 21, 305-312, 1991.
40. Tiegs, S. L., Russell, D. M., and Nemazee, D. Receptor editing in self-reactive bone marrow B cells. J. Exp. Med. 177, 1009-1020, 1993.
41. Gay, D., Saunders, T., Camper, S., and Weigert, M. Receptor editing: an approach by autoreactive B cells to escape self tolerance. J. Exp. Med. 177, 999-1008, 1993.