Plasmon-Waveguide Resonance Studies of Ligand Binding to the Human β2-Adrenergic Receptor

Biochemistry

Volumn 43, Issue 11, 2004, Pages 3280-3288

  Devanathan, Savitha ^a   Yao, Zhiping ^b   Salamon, Zdzislaw ^a   Kobilka, Brian ^b   Tollin, Gordon ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANISOTROPY; LIPIDS; MOLECULAR DYNAMICS; MOLECULAR ORIENTATION; PLASMA FILLED WAVEGUIDES; PROTEINS; SPECTROSCOPIC ANALYSIS;

BINDING CONSTANT; LIGANDS;

BIOCHEMISTRY;

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ADRENALIN; ALPRENOLOL; BETA 2 ADRENERGIC RECEPTOR; DOBUTAMINE; ISOPRENALINE; PHOSPHATIDYLCHOLINE; PROTEOLIPID;

ANISOTROPY; ARTICLE; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; EGG; HUMAN; LIGAND BINDING; LIPID BILAYER; LIPID MEMBRANE; MOLECULAR INTERACTION; OPTICS; PLASMON WAVEGUIDE RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; SPECTROSCOPY;

ADRENERGIC AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ALPRENOLOL; ANISOTROPY; EPINEPHRINE; HUMANS; ISOPROTERENOL; KINETICS; LIGANDS; LIPID BILAYERS; PHOSPHATIDYLCHOLINES; PROPANOLAMINES; PROTEIN BINDING; PROTEOLIPIDS; RECEPTORS, ADRENERGIC, BETA-2; SPECTRUM ANALYSIS; SURFACE PLASMON RESONANCE;

EID: 1542743648     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035825a     Document Type: Article

References (34)

1. Schwartz, T. W. (1996) Molecular structure of G protein coupled receptors, in Molecular Structure of G Protein Coupled Receptors (Foreman, J. C., and Johansen, T., Eds.) pp 65-84, CRC Press, Boca Raton, FL.
2. Kolakowski, L. F., Jr. (1994) GCRDb: a G-protein coupled receptor database, Recept. Channels 2, 1-7.
3. Hamm, H. E. (1998) The many faces of G-protein signaling, J. Biol. Chem. 273, 669-672.
4. Hein, L., and Kobilka, B. K. (1995) Adrenergic receptor signal transduction and regulation, Neuropharmacology 34, 357-366.
5. Gether, U., and Kobilka, B. K. (1998) G protein-coupled receptors. II. Mechanism of agonist activation, J. Biol. Chem. 273, 17979-17982.
6. Gether, U. (2000) Uncovering molecular mechanisms involved in activation of G protein-coupled receptors, Endocr. Rev. 21, 90-113.
7. 2-adrenergic receptor: evidence for ligand-specific conformational changes, J. Biol. Chem. 270, 28268-28275.
8. 2 adrenergic receptor, Proc. Natl. Acad. Sci. U.S.A. 98, 5997-6002.
9. 2 adrenergic receptor: Observation of conformational substates in a membrane protein, Proc. Natl. Acad. Sci. U.S.A. 98, 8469-8474.
10. Salamon, Z., Cowell, S., Varga, E., Yamamura, H. I., Hruby, V. J., and Tollin, G. (2000) Plasmon resonance studies of agonist/antagonist binding to the human 6-opioid receptor: new structural insights into receptor-ligand interactions, Biophys. J. 79, 2463-2474.
11. Salamon, Z., Hruby, V. J., Tollin, G., and Cowell, S. M. (2002) Binding of agonists, antagonists and inverse agonists to the human δ-opioid receptor produces distinctly different conformational states distinguishable by plasmon-waveguide resonance spectroscopy, J. Pept. Res. 60, 322-328.
12. Kobilka, B. K. (1995) Amino and carboxyl terminal modifications to facilitate the production and purification of a G protein-coupled receptor, Anal. Biochem. 231, 269-271.
13. Salamon, Z., Macleod, H. A., and Tollin, G. (1997) Coupled plasmon-waveguide resonators: a new spectroscopic tool for probing proteolipid film structure and properties, Biophys. J. 73, 2791-2797.
14. Salamon, Z., Lindblom, G., Rilfors, L., Linde, K., and Tollin, G. (2000) Interaction of phosphatidylserine synthase from E. coli with lipid bilayers: coupled plasmon-waveguide resonance spectroscopy studies, Biophys. J. 78, 1400-1412.
15. Gee, M. L., Healy, T. W., and White, L. R. (1990) Hydrophobicity effects in the condensation of water films on quartz, J. Colloid Interface Sci. 83, 6258-6262.
16. Silberzan, P., Leger, L., Auserre, D., and Benattar, J. J. (1991) Silanation of silica surfaces. A new method of constructing pure or mixed monolayers, Langmuir 7, 1647-1651.
17. Salamon, Z., Huang, D., Cramer, W. A., and Tollin, G. (1998) Coupled plasmon-waveguide resonance spectroscopy studies of the cytochrome b6f/plastocyanin system in supported lipid bilayer membranes, Biophys. J. 75, 1874-1885.
18. Salamon, Z., and Tollin, G. (1999) Surface plasmon resonance: theoretical principles, in Encyclopedia of Spectroscopy and Spectrometry, Vol. 3, pp 2311-2319, Academic Press, New York.
19. Salamon, Z., and Tollin, G. (1999) Surface plasmon resonance: applications, in Encyclopedia of Spectroscopy and Spectrometry, Vol. 3, pp 2294-2302, Academic Press, New York.
20. Salamon, Z., Wang, Y., Soulages, J. L., Brown, M. F., and Tollin, G. (1996) Surface plasmon resonance spectroscopy studies of membrane proteins: transducin binding and activation by rhodopsin monitored in thin membrane films, Biophys. J. 71, 283-294.
21. Salamon, Z., Brown, M. F., and Tollin, G. (1999) Plasmon resonance spectroscopy: probing interactions within membranes, Trends Biochem. Sci. 24, 213-219.
22. Palanche, T., Ilien, B., Zoffmann, S., Reck, M. Bucher, B., Edelstein, S. J., and Galzi, J.-L. (2001) The Neurokinin A receptor activates calcium and cAMP responses through distinct conformational states, J. Biol. Chem. 276, 34853-34861.
23. 125I]iodoclonidine, a novel radiolabeled agonist for studying central alpha2-adrenergic receptors, Mol. Pharmacol. 38, 348-356.
24. Schlein, M., Havelund, S., Kristensen, C., Dunn, M. F., and Kaarsholm, N. C. (2000) Ligand-induced conformational change in the minimized insulin receptor, J. Mol. Biol. 303, 161-169.
25. 2 adrenergic receptor, J. Biol. Chem. 276, 24433-24436.
26. Kenakin, T. P. (2002) Efficacy at G protein coupled receptors, Annu. Rev. Pharmacol. Toxicol. 42, 349-379.
27. Kenakin, T. P. (2002) Efficacy at G protein coupled receptors, Nat. Rev. Drug Discov. 1, 103-109.
28. Kenakin, T. P. (2003) Ligand-selective receptor conformations revisited: the promise and the problem, Trends Pharmacol. Sci. 24, 346-354.
29. 2-adrenergic receptor within the fourth transmembrane domain alters ligand binding and functional properties of the receptor, J. Biol Chem. 268, 23116-23121.
30. 2-selective adrenoceptor antagonist (ICI-118,551), J. Cardiovasc. Pharmacol. 5, 430-437.
31. Strosberg, A. D. (1997) Structure and function of the β3-adrenergic receptor, Annu. Rev. Pharmacol. Toxicol. 37, 421-450.
32. 2-receptors, J. Biol. Chem. 262, 14843-14846.
33. 2-adrenoceptors, Br. J. Pharmacol. 131, 124-130.
34. 2-adrenergic receptor: extending the ternary complex model, J. Biol. Chem. 268, 4625-4636.