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Volumn 644, Issue 1-3, 2010, Pages 24-31

Haloperidol causes cytoskeletal collapse in N1E-115 cells through tau hyperphosphorylation induced by oxidative stress: Implications for neurodevelopment

Author keywords

Cytoskeletal; Growth cones; Haloperidol; Melatonin; Neurites; Neurodevelopment

Indexed keywords

HALOPERIDOL; MELATONIN; TAU PROTEIN;

EID: 77955773599     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.06.057     Document Type: Article
Times cited : (22)

References (66)
  • 3
    • 62649133735 scopus 로고    scopus 로고
    • White matter abnormalities in schizophrenia patients with tardive dyskinesia: a diffusion tensor image study
    • Bai Y.M., Chou K.H., Lin C.P., Chen I.Y., Li C.T., Yang K.C., Chou Y.H., Su T.P. White matter abnormalities in schizophrenia patients with tardive dyskinesia: a diffusion tensor image study. Schizophr. Res. 2009, 109:167-181.
    • (2009) Schizophr. Res. , vol.109 , pp. 167-181
    • Bai, Y.M.1    Chou, K.H.2    Lin, C.P.3    Chen, I.Y.4    Li, C.T.5    Yang, K.C.6    Chou, Y.H.7    Su, T.P.8
  • 4
    • 33847616880 scopus 로고    scopus 로고
    • Melatonin induces neuritogenesis at early stages in N1E-115 cells through actin rearrangements via activation of protein kinase C and Rho-associated kinase
    • Bellon A., Ortiz-Lopez L., Ramirez-Rodriguez G., Anton-Tay F., Benitez-King G. Melatonin induces neuritogenesis at early stages in N1E-115 cells through actin rearrangements via activation of protein kinase C and Rho-associated kinase. J. Pineal Res. 2007, 42:214-221.
    • (2007) J. Pineal Res. , vol.42 , pp. 214-221
    • Bellon, A.1    Ortiz-Lopez, L.2    Ramirez-Rodriguez, G.3    Anton-Tay, F.4    Benitez-King, G.5
  • 5
    • 33644920991 scopus 로고    scopus 로고
    • Melatonin as a cytoskeletal modulator: implications for cell physiology and disease
    • Benítez-King G. Melatonin as a cytoskeletal modulator: implications for cell physiology and disease. J. Pineal Res. 2006, 40:1-9.
    • (2006) J. Pineal Res. , vol.40 , pp. 1-9
    • Benítez-King, G.1
  • 6
    • 0025678608 scopus 로고
    • Melatonin effects on the cytoskeletal organization of MDCK and neuroblastoma N1E-115 cells
    • Benitez-King G., Huerto-Delgadillo L., Anton-Tay F. Melatonin effects on the cytoskeletal organization of MDCK and neuroblastoma N1E-115 cells. J. Pineal Res. 1990, 9:209-220.
    • (1990) J. Pineal Res. , vol.9 , pp. 209-220
    • Benitez-King, G.1    Huerto-Delgadillo, L.2    Anton-Tay, F.3
  • 7
    • 26844541999 scopus 로고    scopus 로고
    • Melatonin precludes cytoskeletal collapse caused by hidrogen peroxide: participation of protein kinase C
    • Benítez-King G., Ortíz-López L., Jiménez-Rubio G. Melatonin precludes cytoskeletal collapse caused by hidrogen peroxide: participation of protein kinase C. Therapy 2005, 2:762-778.
    • (2005) Therapy , vol.2 , pp. 762-778
    • Benítez-King, G.1    Ortíz-López, L.2    Jiménez-Rubio, G.3
  • 9
    • 0038434113 scopus 로고    scopus 로고
    • Melatonin prevents cytoskeletal alterations and oxidative stress induced by okadaic acid in N1E-115 cells
    • Benítez-King G., Tunez I., Bellon A., Ortíz G.G., Anton-Tay F. Melatonin prevents cytoskeletal alterations and oxidative stress induced by okadaic acid in N1E-115 cells. Exp. Neurol. 2003, 182:151-159.
    • (2003) Exp. Neurol. , vol.182 , pp. 151-159
    • Benítez-King, G.1    Tunez, I.2    Bellon, A.3    Ortíz, G.G.4    Anton-Tay, F.5
  • 10
    • 0028246105 scopus 로고
    • Orientation, assembly, and stability of microtubule bundles induced by a fragment of tau protein
    • Brandt R., Lee G. Orientation, assembly, and stability of microtubule bundles induced by a fragment of tau protein. Cell Motil. Cytoskeleton 1994, 28:143-154.
    • (1994) Cell Motil. Cytoskeleton , vol.28 , pp. 143-154
    • Brandt, R.1    Lee, G.2
  • 11
    • 0035979806 scopus 로고    scopus 로고
    • Colchicine-induced cytoskeletal collapse and apoptosis in N-18 neuroblastoma cultures is rapidly reversed by applied S-100beta
    • Brewton L.S., Haddad L., Azmitia E.C. Colchicine-induced cytoskeletal collapse and apoptosis in N-18 neuroblastoma cultures is rapidly reversed by applied S-100beta. Brain Res. 2001, 912:9-16.
    • (2001) Brain Res. , vol.912 , pp. 9-16
    • Brewton, L.S.1    Haddad, L.2    Azmitia, E.C.3
  • 13
    • 0041511627 scopus 로고    scopus 로고
    • An integrated analysis of acute treatment-emergent extrapyramidal syndrome in patients with schizophrenia during olanzapine clinical trials: comparisons with placebo, haloperidol, risperidone, or clozapine
    • Carlson C.D., Cavazzoni P.A., Berg P.H., Wei H., Beasley C.M., Kane J.M. An integrated analysis of acute treatment-emergent extrapyramidal syndrome in patients with schizophrenia during olanzapine clinical trials: comparisons with placebo, haloperidol, risperidone, or clozapine. J. Clin. Psychiatry 2003, 64:898-906.
    • (2003) J. Clin. Psychiatry , vol.64 , pp. 898-906
    • Carlson, C.D.1    Cavazzoni, P.A.2    Berg, P.H.3    Wei, H.4    Beasley, C.M.5    Kane, J.M.6
  • 14
    • 3042826534 scopus 로고    scopus 로고
    • Pathophysiology of antipsychotic drug-induced movement disorders
    • Casey D.E. Pathophysiology of antipsychotic drug-induced movement disorders. J. Clin. Psychiatry 2004, 65(Suppl 9):25-28.
    • (2004) J. Clin. Psychiatry , vol.65 , Issue.SUPPL 9 , pp. 25-28
    • Casey, D.E.1
  • 15
    • 0029095351 scopus 로고
    • Evidence that the modulation of membrane-associated protein kinase C activity by an endogenous inhibitor plays a role in N1E-115 murine neuroblastoma cell differentiation
    • Chakravarthy B.R., Wong J., Durkin J.P. Evidence that the modulation of membrane-associated protein kinase C activity by an endogenous inhibitor plays a role in N1E-115 murine neuroblastoma cell differentiation. J. Neurochem. 1995, 65:1569-1579.
    • (1995) J. Neurochem. , vol.65 , pp. 1569-1579
    • Chakravarthy, B.R.1    Wong, J.2    Durkin, J.P.3
  • 16
    • 0029913279 scopus 로고    scopus 로고
    • Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
    • Creese I., Burt D.R., Snyder S.H. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. J. Neuropsychiatry Clin. Neurosci. 1996, 8:223-226.
    • (1996) J. Neuropsychiatry Clin. Neurosci. , vol.8 , pp. 223-226
    • Creese, I.1    Burt, D.R.2    Snyder, S.H.3
  • 17
    • 0141953237 scopus 로고    scopus 로고
    • Cytoskeletal dynamics and transport in growth cone motility and axon guidance
    • Dent E.W., Gertler F.B. Cytoskeletal dynamics and transport in growth cone motility and axon guidance. Neuron 2003, 40:209-227.
    • (2003) Neuron , vol.40 , pp. 209-227
    • Dent, E.W.1    Gertler, F.B.2
  • 18
    • 0033570357 scopus 로고    scopus 로고
    • Reorganization and movement of microtubules in axonal growth cones and developing interstitial branches
    • Dent E.W., Callaway J.L., Szebenyi G., Baas P.W., Kalil K. Reorganization and movement of microtubules in axonal growth cones and developing interstitial branches. J. Neurosci. 1999, 19:8894-8908.
    • (1999) J. Neurosci. , vol.19 , pp. 8894-8908
    • Dent, E.W.1    Callaway, J.L.2    Szebenyi, G.3    Baas, P.W.4    Kalil, K.5
  • 19
    • 41649112915 scopus 로고    scopus 로고
    • Antipsychotic drugs alter neuronal development including ALM neuroblast migration and PLM axonal outgrowth in Caenorhabditis elegans
    • Donohoe D.R., Weeks K., Aamodt E.J., Dwyer D.S. Antipsychotic drugs alter neuronal development including ALM neuroblast migration and PLM axonal outgrowth in Caenorhabditis elegans. Int. J. Dev. Neurosci. 2008, 26:371-380.
    • (2008) Int. J. Dev. Neurosci. , vol.26 , pp. 371-380
    • Donohoe, D.R.1    Weeks, K.2    Aamodt, E.J.3    Dwyer, D.S.4
  • 20
    • 0037414404 scopus 로고    scopus 로고
    • Cytotoxicity of conventional and atypical antipsychotic drugs in relation to glucose metabolism
    • Dwyer D.S., Lu X.H., Bradley R.J. Cytotoxicity of conventional and atypical antipsychotic drugs in relation to glucose metabolism. Brain Res. 2003, 971:31-39.
    • (2003) Brain Res. , vol.971 , pp. 31-39
    • Dwyer, D.S.1    Lu, X.H.2    Bradley, R.J.3
  • 21
    • 0033792070 scopus 로고    scopus 로고
    • Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins
    • Eidenmuller J., Fath T., Hellwig A., Reed J., Sontag E., Brandt R. Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins. Biochemistry 2000, 39:13166-13175.
    • (2000) Biochemistry , vol.39 , pp. 13166-13175
    • Eidenmuller, J.1    Fath, T.2    Hellwig, A.3    Reed, J.4    Sontag, E.5    Brandt, R.6
  • 22
    • 0027269557 scopus 로고
    • Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays
    • Gorczyca W., Gong J., Darzynkiewicz Z. Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res. 1993, 53:1945-1951.
    • (1993) Cancer Res. , vol.53 , pp. 1945-1951
    • Gorczyca, W.1    Gong, J.2    Darzynkiewicz, Z.3
  • 23
    • 0026683725 scopus 로고
    • The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs
    • Gustke N., Steiner B., Mandelkow E.M., Biernat J., Meyer H.E., Goedert M., Mandelkow E. The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs. FEBS Lett. 1992, 307:199-205.
    • (1992) FEBS Lett. , vol.307 , pp. 199-205
    • Gustke, N.1    Steiner, B.2    Mandelkow, E.M.3    Biernat, J.4    Meyer, H.E.5    Goedert, M.6    Mandelkow, E.7
  • 26
    • 0033790679 scopus 로고    scopus 로고
    • The effect of ammonium chloride on metabolism of primary neurons and neuroblastoma cells in vitro
    • Haghighat N., McCandless D.W., Geraminegad P. The effect of ammonium chloride on metabolism of primary neurons and neuroblastoma cells in vitro. Metab. Brain Dis. 2000, 15:151-162.
    • (2000) Metab. Brain Dis. , vol.15 , pp. 151-162
    • Haghighat, N.1    McCandless, D.W.2    Geraminegad, P.3
  • 27
    • 37549055477 scopus 로고    scopus 로고
    • The nitrone disodium 2, 4-sulphophenyl-N-tert-butylnitrone is without cytoprotective effect on sodium nitroprusside-induced cell death in N1E-115 neuroblastoma cells in vitro
    • Hainsworth A.H., Bhuiyan N., Green A.R. The nitrone disodium 2, 4-sulphophenyl-N-tert-butylnitrone is without cytoprotective effect on sodium nitroprusside-induced cell death in N1E-115 neuroblastoma cells in vitro. J. Cereb. Blood Flow Metab. 2008, 28:24-28.
    • (2008) J. Cereb. Blood Flow Metab. , vol.28 , pp. 24-28
    • Hainsworth, A.H.1    Bhuiyan, N.2    Green, A.R.3
  • 28
    • 35649008994 scopus 로고    scopus 로고
    • Effects of haloperidol, clozapine and olanzapine on the survival of human neuronal and immune cells in vitro
    • Heiser P., Enning F., Krieg J.C., Vedder H. Effects of haloperidol, clozapine and olanzapine on the survival of human neuronal and immune cells in vitro. J. Psychopharmacol. 2007, 21:851-856.
    • (2007) J. Psychopharmacol. , vol.21 , pp. 851-856
    • Heiser, P.1    Enning, F.2    Krieg, J.C.3    Vedder, H.4
  • 29
    • 0141894133 scopus 로고    scopus 로고
    • Neuronal polarity and trafficking
    • Horton A.C., Ehlers M.D. Neuronal polarity and trafficking. Neuron 2003, 40:277-295.
    • (2003) Neuron , vol.40 , pp. 277-295
    • Horton, A.C.1    Ehlers, M.D.2
  • 30
    • 49149105134 scopus 로고    scopus 로고
    • Cytosolic abnormally hyperphosphorylated tau but not paired helical filaments sequester normal MAPs and inhibit microtubule assembly
    • Iqbal K., Alonso A.C., Grundke-Iqbal I. Cytosolic abnormally hyperphosphorylated tau but not paired helical filaments sequester normal MAPs and inhibit microtubule assembly. J. Alzheimers Dis. 2008, 14:365-370.
    • (2008) J. Alzheimers Dis. , vol.14 , pp. 365-370
    • Iqbal, K.1    Alonso, A.C.2    Grundke-Iqbal, I.3
  • 32
    • 77955768670 scopus 로고    scopus 로고
    • Melatonin elicits neuritogenesis and reverses tau hyperphosphorylation in N1E-115 neuroblastoma cells treated with okadaic acid
    • Nova Science Publishers, Hauppauge, NY, A.J. Fernández (Ed.)
    • Jiménez-Rubio G., Benítez-King G., Ortíz-López L. Melatonin elicits neuritogenesis and reverses tau hyperphosphorylation in N1E-115 neuroblastoma cells treated with okadaic acid. Focus on Neuroblastoma Research 2007, 99-117. Nova Science Publishers, Hauppauge, NY. A.J. Fernández (Ed.).
    • (2007) Focus on Neuroblastoma Research , pp. 99-117
    • Jiménez-Rubio, G.1    Benítez-King, G.2    Ortíz-López, L.3
  • 33
    • 0020334196 scopus 로고
    • Characteristics of the electrical response to dopamine in neuroblastoma cells
    • Kato E., Narahashi T. Characteristics of the electrical response to dopamine in neuroblastoma cells. J. Physiol. 1982, 333:213-226.
    • (1982) J. Physiol. , vol.333 , pp. 213-226
    • Kato, E.1    Narahashi, T.2
  • 34
    • 66349108700 scopus 로고    scopus 로고
    • Reactive oxygen species regulate a slingshot-cofilin activation pathway
    • Kim J.S., Huang T.Y., Bokoch G.M. Reactive oxygen species regulate a slingshot-cofilin activation pathway. Mol. Biol. Cell 2009, 20:2650-2660.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 2650-2660
    • Kim, J.S.1    Huang, T.Y.2    Bokoch, G.M.3
  • 35
    • 0032514249 scopus 로고    scopus 로고
    • Melatonin protects 6-OHDA-induced neuronal death of nigrostriatal dopaminergic system
    • Kim Y.S., Joo W.S., Jin B.K., Cho Y.H., Baik H.H., Park C.W. Melatonin protects 6-OHDA-induced neuronal death of nigrostriatal dopaminergic system. NeuroReport 1998, 9:2387-2390.
    • (1998) NeuroReport , vol.9 , pp. 2387-2390
    • Kim, Y.S.1    Joo, W.S.2    Jin, B.K.3    Cho, Y.H.4    Baik, H.H.5    Park, C.W.6
  • 37
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 38
    • 0023204820 scopus 로고
    • Penfluridol, chlorprothixene and haloperidol block fast axonal transport in an order of potency consistent with a mechanism related to inhibition of calmodulin
    • Lavoie P.A. Penfluridol, chlorprothixene and haloperidol block fast axonal transport in an order of potency consistent with a mechanism related to inhibition of calmodulin. Neuropharmacology 1987, 26:1359-1365.
    • (1987) Neuropharmacology , vol.26 , pp. 1359-1365
    • Lavoie, P.A.1
  • 39
    • 0141818083 scopus 로고    scopus 로고
    • Membrane and cytoskeleton dynamics during axonal elongation and stabilization
    • Ledesma M.D., Dotti C.G. Membrane and cytoskeleton dynamics during axonal elongation and stabilization. Int. Rev. Cytol. 2003, 227:183-219.
    • (2003) Int. Rev. Cytol. , vol.227 , pp. 183-219
    • Ledesma, M.D.1    Dotti, C.G.2
  • 40
    • 33645472043 scopus 로고    scopus 로고
    • On the use of neuro-2a neuroblastoma cells versus intact neurons in primary culture for neurotoxicity studies
    • LePage K.T., Dickey R.W., Gerwick W.H., Jester E.L., Murray T.F. On the use of neuro-2a neuroblastoma cells versus intact neurons in primary culture for neurotoxicity studies. Crit. Rev. Neurobiol. 2005, 17:27-50.
    • (2005) Crit. Rev. Neurobiol. , vol.17 , pp. 27-50
    • LePage, K.T.1    Dickey, R.W.2    Gerwick, W.H.3    Jester, E.L.4    Murray, T.F.5
  • 41
    • 0035058055 scopus 로고    scopus 로고
    • Antipsychotic treatment induces alterations in dendrite- and spine-associated proteins in dopamine-rich areas of the primate cerebral cortex
    • Lidow M.S., Song Z.M., Castner S.A., Allen P.B., Greengard P., Goldman-Rakic P.S. Antipsychotic treatment induces alterations in dendrite- and spine-associated proteins in dopamine-rich areas of the primate cerebral cortex. Biol. Psychiatry 2001, 49:1-12.
    • (2001) Biol. Psychiatry , vol.49 , pp. 1-12
    • Lidow, M.S.1    Song, Z.M.2    Castner, S.A.3    Allen, P.B.4    Greengard, P.5    Goldman-Rakic, P.S.6
  • 42
    • 67349086281 scopus 로고    scopus 로고
    • The trip of the tip: understanding the growth cone machinery
    • Lowery L.A., Van V.D. The trip of the tip: understanding the growth cone machinery. Nat. Rev. Mol. Cell Biol. 2009, 10:332-343.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 332-343
    • Lowery, L.A.1    Van, V.D.2
  • 44
    • 0026467059 scopus 로고
    • Coadministration of haloperidol and SCH-23390 prevents the increase in "perforated" synapses due to either drug alone
    • Meshul C.K., Janowsky A., Casey D.E., Stallbaumer R.K., Taylor B. Coadministration of haloperidol and SCH-23390 prevents the increase in "perforated" synapses due to either drug alone. Neuropsychopharmacology 1992, 7:285-293.
    • (1992) Neuropsychopharmacology , vol.7 , pp. 285-293
    • Meshul, C.K.1    Janowsky, A.2    Casey, D.E.3    Stallbaumer, R.K.4    Taylor, B.5
  • 46
    • 33746091323 scopus 로고    scopus 로고
    • Nitric oxide and synaptic dynamics in the adult brain: physiopathological aspects
    • Moreno-Lopez B., Gonzalez-Forero D. Nitric oxide and synaptic dynamics in the adult brain: physiopathological aspects. Rev. Neurosci. 2006, 17:309-357.
    • (2006) Rev. Neurosci. , vol.17 , pp. 309-357
    • Moreno-Lopez, B.1    Gonzalez-Forero, D.2
  • 48
    • 0037304409 scopus 로고    scopus 로고
    • Possible mechanism of action in melatonin attenuation of haloperidol-induced orofacial dyskinesia
    • Naidu P.S., Singh A., Kaur P., Sandhir R., Kulkarni S.K. Possible mechanism of action in melatonin attenuation of haloperidol-induced orofacial dyskinesia. Pharmacol. Biochem. Behav. 2003, 74:641-648.
    • (2003) Pharmacol. Biochem. Behav. , vol.74 , pp. 641-648
    • Naidu, P.S.1    Singh, A.2    Kaur, P.3    Sandhir, R.4    Kulkarni, S.K.5
  • 50
    • 57149147490 scopus 로고    scopus 로고
    • ROCK-regulated cytoskeletal dynamics participate in the inhibitory effect of melatonin on cancer cell migration
    • Ortíz-López L., Morales-Mulia S., Ramírez-Rodríguez G., Benítez-King G. ROCK-regulated cytoskeletal dynamics participate in the inhibitory effect of melatonin on cancer cell migration. J. Pineal Res. 2009, 46:15-21.
    • (2009) J. Pineal Res. , vol.46 , pp. 15-21
    • Ortíz-López, L.1    Morales-Mulia, S.2    Ramírez-Rodríguez, G.3    Benítez-King, G.4
  • 52
    • 59449100511 scopus 로고    scopus 로고
    • Protection against amyloid beta cytotoxicity by sulforaphane: role of the proteasome
    • Park H.M., Kim J.A., Kwak M.K. Protection against amyloid beta cytotoxicity by sulforaphane: role of the proteasome. Arch. Pharm. Res. 2009, 32:109-115.
    • (2009) Arch. Pharm. Res. , vol.32 , pp. 109-115
    • Park, H.M.1    Kim, J.A.2    Kwak, M.K.3
  • 53
    • 0032531429 scopus 로고    scopus 로고
    • Induction of NF-kappaB activity during haloperidol-induced oxidative toxicity in clonal hippocampal cells: suppression of NF-kappaB and neuroprotection by antioxidants
    • Post A., Holsboer F., Behl C. Induction of NF-kappaB activity during haloperidol-induced oxidative toxicity in clonal hippocampal cells: suppression of NF-kappaB and neuroprotection by antioxidants. J. Neurosci. 1998, 18:8236-8246.
    • (1998) J. Neurosci. , vol.18 , pp. 8236-8246
    • Post, A.1    Holsboer, F.2    Behl, C.3
  • 54
    • 0031872081 scopus 로고    scopus 로고
    • Melatonin, active oxygen species and neurological damage
    • Reiter R.J. Melatonin, active oxygen species and neurological damage. Drug News Perspect. 1998, 11:291-296.
    • (1998) Drug News Perspect. , vol.11 , pp. 291-296
    • Reiter, R.J.1
  • 55
    • 57149136477 scopus 로고    scopus 로고
    • Melatonin reduces oxidative/nitrosative stress due to drugs, toxins, metals, and herbicides
    • Reiter R.J., Korkmaz A., Paredes S.D., Manchester L.C., Tan D.X. Melatonin reduces oxidative/nitrosative stress due to drugs, toxins, metals, and herbicides. Neuro Endocrinol. Lett. 2008, 29:609-613.
    • (2008) Neuro Endocrinol. Lett. , vol.29 , pp. 609-613
    • Reiter, R.J.1    Korkmaz, A.2    Paredes, S.D.3    Manchester, L.C.4    Tan, D.X.5
  • 56
    • 0034087775 scopus 로고    scopus 로고
    • The current status of tardive dyskinesia
    • Sachdev P.S. The current status of tardive dyskinesia. Aust. N. Z. J. Psychiatry 2000, 34:355-369.
    • (2000) Aust. N. Z. J. Psychiatry , vol.34 , pp. 355-369
    • Sachdev, P.S.1
  • 57
    • 75749154521 scopus 로고    scopus 로고
    • Comparison of vitamin E, l-carnitine and melatonin in ameliorating carbon tetrachloride and diabetes induced hepatic oxidative stress
    • Shaker M.E., Houssen M.E., Abo-Hashem E.M., Ibrahim T.M. Comparison of vitamin E, l-carnitine and melatonin in ameliorating carbon tetrachloride and diabetes induced hepatic oxidative stress. J. Physiol. Biochem. 2009, 65:225-233.
    • (2009) J. Physiol. Biochem. , vol.65 , pp. 225-233
    • Shaker, M.E.1    Houssen, M.E.2    Abo-Hashem, E.M.3    Ibrahim, T.M.4
  • 58
    • 0017885503 scopus 로고
    • Proteins from morphologically differentiated neuroblastoma cells promote tubulin polymerization
    • Seeds N.W., Maccioni R.B. Proteins from morphologically differentiated neuroblastoma cells promote tubulin polymerization. J. Cell Biol. 1978, 76:547-555.
    • (1978) J. Cell Biol. , vol.76 , pp. 547-555
    • Seeds, N.W.1    Maccioni, R.B.2
  • 59
    • 0033844266 scopus 로고    scopus 로고
    • Development of the nigrostriatal dopamine neuron and the pathways in the basal ganglia
    • Segawa M. Development of the nigrostriatal dopamine neuron and the pathways in the basal ganglia. Brain Dev. 2000, 22(Suppl 1):S1-S4.
    • (2000) Brain Dev. , vol.22 , Issue.SUPPL 1
    • Segawa, M.1
  • 61
    • 0033305177 scopus 로고    scopus 로고
    • High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus
    • Skinner D.C., Malpaux B. High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus. Endocrinology 1999, 140:4399-4405.
    • (1999) Endocrinology , vol.140 , pp. 4399-4405
    • Skinner, D.C.1    Malpaux, B.2
  • 63
    • 62349133406 scopus 로고    scopus 로고
    • Neurochemistry, neuropathology, and heredity in SAMP8: a mouse model of senescence
    • Tomobe K., Nomura Y. Neurochemistry, neuropathology, and heredity in SAMP8: a mouse model of senescence. Neurochem. Res. 2009, 34:660-669.
    • (2009) Neurochem. Res. , vol.34 , pp. 660-669
    • Tomobe, K.1    Nomura, Y.2
  • 64
    • 0016431904 scopus 로고
    • Ionic excitation of a clone of mouse neuroblastoma
    • Tuttle J.B., Richelson E. Ionic excitation of a clone of mouse neuroblastoma. Brain Res. 1975, 84:129-135.
    • (1975) Brain Res. , vol.84 , pp. 129-135
    • Tuttle, J.B.1    Richelson, E.2
  • 65
    • 0027300771 scopus 로고
    • Protection of the axonal cytoskeleton in anoxic optic nerve by decreased extracellular calcium
    • Waxman S.G., Black J.A., Ransom B.R., Stys P.K. Protection of the axonal cytoskeleton in anoxic optic nerve by decreased extracellular calcium. Brain Res. 1993, 614:137-145.
    • (1993) Brain Res. , vol.614 , pp. 137-145
    • Waxman, S.G.1    Black, J.A.2    Ransom, B.R.3    Stys, P.K.4
  • 66
    • 4344607957 scopus 로고    scopus 로고
    • Effect of inhibiting melatonin biosynthesis on spatial memory retention and tau phosphorylation in rat
    • Zhu L.Q., Wang S.H., Ling Z.Q., Wang D.L., Wang J.Z. Effect of inhibiting melatonin biosynthesis on spatial memory retention and tau phosphorylation in rat. J. Pineal Res. 2004, 37:71-77.
    • (2004) J. Pineal Res. , vol.37 , pp. 71-77
    • Zhu, L.Q.1    Wang, S.H.2    Ling, Z.Q.3    Wang, D.L.4    Wang, J.Z.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.