-
1
-
-
0030271381
-
Combination therapy with MK-801 and alpha-phenyl-tert-butyl-nitrone enhances protection against ischemic neuronal damage in organotypic hippocampal slice cultures
-
Barth A, Barth L, Newell DW (1996) Combination therapy with MK-801 and alpha-phenyl-tert-butyl-nitrone enhances protection against ischemic neuronal damage in organotypic hippocampal slice cultures. Exp Neurol 141:330-6
-
(1996)
Exp Neurol
, vol.141
, pp. 330-336
-
-
Barth, A.1
Barth, L.2
Newell, D.W.3
-
2
-
-
0029153913
-
Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures
-
Bonfoco E, Krainc D, Ankarcrona M, Nicotera P, Lipton SA (1995) Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci USA 92:7162-6
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7162-7166
-
-
Bonfoco, E.1
Krainc, D.2
Ankarcrona, M.3
Nicotera, P.4
Lipton, S.A.5
-
3
-
-
37549024160
-
-
Culot M, Rentfel M, Dehouck M, Lundquist S, Cecchelli R (2006) NXY-059, a free radical-trapping neuroprotectant protects the blood brain barrier (BBB) in ischaemic conditions in vitro. Soc for Neurosci abstract, No 679.13
-
Culot M, Rentfel M, Dehouck M, Lundquist S, Cecchelli R (2006) NXY-059, a free radical-trapping neuroprotectant protects the blood brain barrier (BBB) in ischaemic conditions in vitro. Soc for Neurosci abstract, No 679.13
-
-
-
-
4
-
-
0025773785
-
Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures
-
Dawson VL, Dawson TM, London ED, Bredt DS, Snyder SH (1991) Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc Natl Acad Sci USA 88:6368-71
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 6368-6371
-
-
Dawson, V.L.1
Dawson, T.M.2
London, E.D.3
Bredt, D.S.4
Snyder, S.H.5
-
5
-
-
0037111301
-
In vitro blood-brain barrier permeability and cerebral endothelial cell uptake of the neuroprotective nitrone compound NXY-059 in normoxic, hypoxic and ischemic conditions
-
Dehouck MP, Cecchelli R, Green AR, Renftel M, Lundquist S (2002) In vitro blood-brain barrier permeability and cerebral endothelial cell uptake of the neuroprotective nitrone compound NXY-059 in normoxic, hypoxic and ischemic conditions. Brain Res 955:229-35
-
(2002)
Brain Res
, vol.955
, pp. 229-235
-
-
Dehouck, M.P.1
Cecchelli, R.2
Green, A.R.3
Renftel, M.4
Lundquist, S.5
-
6
-
-
32144461723
-
Stroke and neurovascular protection
-
del Zoppo GJ (2006) Stroke and neurovascular protection. New Engl J Med 354:553-5
-
(2006)
New Engl J Med
, vol.354
, pp. 553-555
-
-
del Zoppo, G.J.1
-
7
-
-
1542268910
-
Protein oxidation and the degradation of oxidized proteins in the rat oligodendrocyte cell line OLN 93-antioxidative effect of the intracellular spin trapping agent PBN
-
Ernst A, Stolzing A, Sandig G, Grune T (2004) Protein oxidation and the degradation of oxidized proteins in the rat oligodendrocyte cell line OLN 93-antioxidative effect of the intracellular spin trapping agent PBN. Mol Brain Res 122:126-32
-
(2004)
Mol Brain Res
, vol.122
, pp. 126-132
-
-
Ernst, A.1
Stolzing, A.2
Sandig, G.3
Grune, T.4
-
8
-
-
85056018648
-
Free radical trapping as a therapeutic approach to neuroprotection in stroke: Experimental and clinical studies with NXY-059 and free radical scavengers
-
Green AR, Ashwood T (2005) Free radical trapping as a therapeutic approach to neuroprotection in stroke: experimental and clinical studies with NXY-059 and free radical scavengers. Current Drug Targets - CNS Neurol Dis 16:91-7
-
(2005)
Current Drug Targets - CNS Neurol Dis
, vol.16
, pp. 91-97
-
-
Green, A.R.1
Ashwood, T.2
-
9
-
-
0345118252
-
Nitrones as neuroprotective agents in cerebral ischaemia, with particular reference to NXY-059
-
Green AR, Ashwood T, Odergren T, Jackson DM (2003) Nitrones as neuroprotective agents in cerebral ischaemia, with particular reference to NXY-059. Pharmacol Ther 100:195-214
-
(2003)
Pharmacol Ther
, vol.100
, pp. 195-214
-
-
Green, A.R.1
Ashwood, T.2
Odergren, T.3
Jackson, D.M.4
-
10
-
-
0035900740
-
Integrin-linked kinase controls neurite outgrowth in N1E-115 neuroblastoma cells
-
Ishii T, Satoh E, Nishimura M (2001) Integrin-linked kinase controls neurite outgrowth in N1E-115 neuroblastoma cells. J Biol Chem 276:42994-3003
-
(2001)
J Biol Chem
, vol.276
, pp. 42994-43003
-
-
Ishii, T.1
Satoh, E.2
Nishimura, M.3
-
11
-
-
0346114246
-
Detection and identification of short-lived free radicals by an electron spin resonance trapping technique
-
Janzen EG, Blackburn BJ (1968) Detection and identification of short-lived free radicals by an electron spin resonance trapping technique. J Am Chem Soc 90:5909-10
-
(1968)
J Am Chem Soc
, vol.90
, pp. 5909-5910
-
-
Janzen, E.G.1
Blackburn, B.J.2
-
12
-
-
0034721770
-
Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen - role of reactive oxygen and nitrogen species
-
Kotamraju S, Konorev EA, Joseph J, Kalyanaraman B 2000 Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen - role of reactive oxygen and nitrogen species. J Biol Chem 275:33585-92
-
(2000)
J Biol Chem
, vol.275
, pp. 33585-33592
-
-
Kotamraju, S.1
Konorev, E.A.2
Joseph, J.3
Kalyanaraman, B.4
-
13
-
-
32144453826
-
NXY-059 for acute ischemic stroke
-
Lees KR, Zivin JA, Ashwood T, Davalos A, Davis SM, Diener HC, Grotta J, Lyden P, Shuaib A, Hardemark H-G, Wasiewski W (2006) NXY-059 for acute ischemic stroke. New Engl J Med 354:588-600
-
(2006)
New Engl J Med
, vol.354
, pp. 588-600
-
-
Lees, K.R.1
Zivin, J.A.2
Ashwood, T.3
Davalos, A.4
Davis, S.M.5
Diener, H.C.6
Grotta, J.7
Lyden, P.8
Shuaib, A.9
Hardemark, H.-G.10
Wasiewski, W.11
-
14
-
-
0035054659
-
Comparison of the radical trapping ability of PBN, S-PPBN and NXY-059
-
Maples KR, Ma F, Zhang YK (2001) Comparison of the radical trapping ability of PBN, S-PPBN and NXY-059. Free Radical Res 34:417-26
-
(2001)
Free Radical Res
, vol.34
, pp. 417-426
-
-
Maples, K.R.1
Ma, F.2
Zhang, Y.K.3
-
15
-
-
0042919342
-
Functional and histological evidence for the protective effect of NXY-059 in a primate model of stroke when given 4 h after occlusion
-
Marshall JW, Cummings RM, Bowes LJ, Ridley RM, Green AR (2003) Functional and histological evidence for the protective effect of NXY-059 in a primate model of stroke when given 4 h after occlusion. Stroke 34:2228-33
-
(2003)
Stroke
, vol.34
, pp. 2228-2233
-
-
Marshall, J.W.1
Cummings, R.M.2
Bowes, L.J.3
Ridley, R.M.4
Green, A.R.5
-
16
-
-
0036152938
-
Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window
-
Sydserff SG, Borelli AR, Green AR, Cross AJ (2002) Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window. Br J Pharmacol 135:103-12
-
(2002)
Br J Pharmacol
, vol.135
, pp. 103-112
-
-
Sydserff, S.G.1
Borelli, A.R.2
Green, A.R.3
Cross, A.J.4
-
17
-
-
0034648089
-
S-nitroso-N-acetylpenicillamine and nitroprusside induce apoptosis in a neuronal cell line by the production of different reactive molecules
-
Terwel D, Nieland LJM, Schutte B, Reutelingsperger CPM, Ramaekers FCS, Steinbusch HWM 2000 S-nitroso-N-acetylpenicillamine and nitroprusside induce apoptosis in a neuronal cell line by the production of different reactive molecules. Eur J Pharmacol 400:19-33
-
(2000)
Eur J Pharmacol
, vol.400
, pp. 19-33
-
-
Terwel, D.1
Nieland, L.J.M.2
Schutte, B.3
Reutelingsperger, C.P.M.4
Ramaekers, F.C.S.5
Steinbusch, H.W.M.6
-
18
-
-
33745888419
-
Cardiac glycosides provide neuroprotection against ischemic stroke: Discovery by a brain slice-based compound screening platform
-
Wang JKT, Portbury S, Thomas MB, Barney S, Ricca DJ, Morris DL, Warner DS, Lo DC (2006) Cardiac glycosides provide neuroprotection against ischemic stroke: discovery by a brain slice-based compound screening platform. Proc Nat Acad Sci USA 103:10461-6
-
(2006)
Proc Nat Acad Sci USA
, vol.103
, pp. 10461-10466
-
-
Wang, J.K.T.1
Portbury, S.2
Thomas, M.B.3
Barney, S.4
Ricca, D.J.5
Morris, D.L.6
Warner, D.S.7
Lo, D.C.8
-
19
-
-
0030053425
-
Protection against peroxynitrite-dependent tyrosine nitration and alpha 1-antiproteinase inactivation by oxidized and reduced lipoic acid
-
Whiteman M, Tritschler H, Halliwell B (1996) Protection against peroxynitrite-dependent tyrosine nitration and alpha 1-antiproteinase inactivation by oxidized and reduced lipoic acid. FEBS Letts 379:74-6
-
(1996)
FEBS Letts
, vol.379
, pp. 74-76
-
-
Whiteman, M.1
Tritschler, H.2
Halliwell, B.3
-
20
-
-
0033777909
-
Attenuation and augmentation of ischaemia-related neuronal death by tumour necrosis factor-alpha in vitro
-
Wilde GJC, Pringle AK, Sundstrom LE, Mann DA, qIannotti F (2000) Attenuation and augmentation of ischaemia-related neuronal death by tumour necrosis factor-alpha in vitro. Eur J Neurosci 12:3863-70
-
(2000)
Eur J Neurosci
, vol.12
, pp. 3863-3870
-
-
Wilde, G.J.C.1
Pringle, A.K.2
Sundstrom, L.E.3
Mann, D.A.4
qIannotti, F.5
-
21
-
-
0030002003
-
Sodium nitroprusside-induced apoptotic cellular death via production of hydrogen peroxide in murine neuroblastoma NLE-115 cells
-
Yamada M, Momose K, Richelson E, Yamada M (1996) Sodium nitroprusside-induced apoptotic cellular death via production of hydrogen peroxide in murine neuroblastoma NLE-115 cells. J Pharmacol Toxicol Methods 35:11-7
-
(1996)
J Pharmacol Toxicol Methods
, vol.35
, pp. 11-17
-
-
Yamada, M.1
Momose, K.2
Richelson, E.3
Yamada, M.4
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