MCT1 genetic polymorphism influence in high intensity circuit training: A pilot study

Journal of Science and Medicine in Sport

Volumn 13, Issue 5, 2010, Pages 526-530

  Cupeiro, Rocío ^a   Benito, Pedro J ^a   Maffulli, Nicola ^c   Calderón, F Javier ^a   González Lamuño, Domingo ^b  

^a UNIVERSIDAD POLITÉCNICA DE MADRID   (Spain)

^b UNIVERSITY OF CANTABRIA   (Spain)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

A1470T polymorphism; Circuit weight training; Lactate accumulation; Monocarboxylate transporters

Indexed keywords

LACTIC ACID; MONOCARBOXYLATE TRANSPORTER 1;

ADULT; ARTICLE; EQUILIBRIUM CONSTANT; EXERCISE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN EXPERIMENT; MALE; MUSCLE CELL; NUCLEOTIDE SEQUENCE; OXIDATION;

EID: 77955665319     PISSN: 14402440     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsams.2009.07.004     Document Type: Article

References (28)

1. Bonen A. The expression of lactate transporters (MCT1 and MCT4) in heart and muscle. Eur J Appl Physiol 2001, 86(November (1)):6-11.
2. Halestrap A.P., Price N.T. The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation. Biochem J 1999, 343(October (Pt 2)):281-299.
3. Juel C. Current aspects of lactate exchange: lactate/H+ transport in human skeletal muscle. Eur J Appl Physiol 2001, 86(November (1)):12-16.
4. Juel C., Halestrap A.P. Lactate transport in skeletal muscle-role and regulation of the monocarboxylate transporter. J Physiol 1999, 517(June (Pt 3)):633-642.
5. McCullagh K.J., Poole R.C., Halestrap A.P., et al. Role of the lactate transporter (MCT1) in skeletal muscles. Am J Physiol 1996, 271(July (1 Pt 1)):E143-E150.
6. McCullagh K.J., Poole R.C., Halestrap A.P., et al. Chronic electrical stimulation increases MCT1 and lactate uptake in red and white skeletal muscle. Am J Physiol 1997, 273(August (2 Pt 1)):E239-E246.
7. Green H., Halestrap A., Mockett C., et al. Increases in muscle MCT are associated with reductions in muscle lactate after a single exercise session in humans. Am J Physiol Endocrinol Metab 2002, 282(January (1)):E154-E160.
8. Thomas C., Perrey S., Lambert K., et al. Monocarboxylate transporters, blood lactate removal after supramaximal exercise, and fatigue indexes in humans. J Appl Physiol 2005, 98(March (3)):804-809.
9. Bonen A., Tonouchi M., Miskovic D., et al. Isoform-specific regulation of the lactate transporters MCT1 and MCT4 by contractile activity. Am J Physiol Endocrinol Metab 2000, 279(November (5)):E1131-E1138.
10. Merezhinskaya N., Fishbein W.N., Davis J.I., et al. Mutations in MCT1 cDNA in patients with symptomatic deficiency in lactate transport. Muscle Nerve 2000, 23(January (1)):90-97.
11. Knuttgen H.G. Strength training and aerobic exercise: comparison and contrast. J Strength Cond Res 2007, 21(Auguat (3)):973-978.
12. Kang J., Hoffman J.R., Im J., et al. Evaluation of physiological responses during recovery following three resistance exercise programs. J Strength Cond Res 2005, 19(May (2)):305-309.
13. Scott C.B. Contribution of blood lactate to the energy expenditure of weight training. J Strength Cond Res 2006, 20(May (2)):404-411.
14. Carter L., Heath B. Somatotyping. Development and applications 1990, University Press, Cambridge.
15. Martin A.D., Spenst L.F., Drinkwater D.T., et al. Anthropometric estimation of muscle mass in men. Med Sci Sports Exerc 1990, 22(October (5)):729-733.
16. Willardson J.M., Burkett L.N. The effect of rest interval length on the sustainability of squat and bench press repetitions. J Strength Cond Res 2006, 20(May (2)):400-403.
17. Kraemer W.J., Ratamess N.A. Hormonal responses and adaptations to resistance exercise and training. Sports Med 2005, 35(4):339-361.
18. Bonen A., McCullagh K.J., Putman C.T., et al. Short-term training increases human muscle MCT1 and femoral venous lactate in relation to muscle lactate. Am J Physiol 1998, 274(January (1 Pt 1)):E102-E107.
19. Dubouchaud H., Butterfield G.E., Wolfel E.E., et al. Endurance training, expression, and physiology of LDH, MCT1, and MCT4 in human skeletal muscle. Am J Physiol Endocrinol Metab 2000, 278(April (4)):E571-E579.
20. Bickham D.C., Bentley D.J., Le Rossignol P.F., et al. The effects of short-term sprint training on MCT expression in moderately endurance-trained runners. Eur J Appl Physiol 2006, 96(April (6)):636-643.
21. Burgomaster K.A., Cermak N.M., Phillips S.M., et al. Divergent response of metabolite transport proteins in human skeletal muscle after sprint interval training and detraining. Am J Physiol Regul Integr Comp Physiol 2007, 292(May (5)):R1970-R1976.
22. Juel C., Klarskov C., Nielsen J.J., et al. Effect of high-intensity intermittent training on lactate and H+ release from human skeletal muscle. Am J Physiol Endocrinol Metab 2004, 286(February (2)):E245-E251.
23. Pilegaard H., Terzis G., Halestrap, et al. Distribution of the lactate/H+ transporter isoforms MCT1 and MCT4 in human skeletal muscle. Am J Physiol 1999, 276(May (5 Pt 1)):E843-E848.
24. Bishop D., Edge J., Thomas C., et al. High-intensity exercise acutely decreases the membrane content of MCT1 and MCT4 and buffer capacity in human skeletal muscle. J Appl Physiol 2007, 102(February (2)):616-621.
25. Gladden L.B. Muscle as a consumer of lactate. Med Sci Sports Exerc 2000, 32(April (4)):764-771.
26. Chen Y.J., Wong S.H., Wong C.K., et al. Effect of preexercise meals with different glycemic indices and loads on metabolic responses and endurance running. Int J Sport Nutr Exerc Metab 2008, 18(June (3)):281-300.
27. Stevenson E., Williams C., Nute M. The influence of the glycaemic index of breakfast and lunch on substrate utilization during the postprandial periods and subsequent exercise. Br J Nutr 2005, 93(June (6)):885-893.
28. Wu C.L., Nicholas C., Williams C., et al. The influence of high-carbohydrate meals with different glycaemic indices on substrate utilization during subsequent exercise. Br J Nutr 2003, 90(December (6)):1049-1056.