Chronic electrical stimulation increases MCT1 and lactate uptake in red and white skeletal muscle

American Journal of Physiology - Endocrinology and Metabolism

Volumn 273, Issue 2 36-2, 1997, Pages

  Mccullagh, Karl J A ^b   Poole, Robert C ^b   Halestrap, Andrew R ^b   Tipton, Keith F ^b   O'Brien, Moira ^b   Bonen, Arend ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

^b NONE

Author keywords

Hindlimb perfusion; Lactate dehydrogenase isoforms; Lactate transporter; Muscle activity; Muscle fiber types

Indexed keywords

CARRIER PROTEIN; LACTATE DEHYDROGENASE; LACTIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; FAST MUSCLE; HINDLIMB; MALE; MUSCLE BLOOD FLOW; MUSCLE EXCITATION; MUSCLE METABOLISM; NONHUMAN; PRIORITY JOURNAL; RAT; SLOW MUSCLE;

EID: 0030805241     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1997.273.2.e239     Document Type: Article

References (13)

1. Annex, B. H., W. E. Kraus, G. L. Dohm, and R. S. Williams. Mitochondrial biogenesis in striated muscles: rapid induction of citrate synthase mRNA by nerve stimulation. Am. J. Physiol. 260 (Cell Physiol. 29): C266-C270, 1991.
2. Bonen, A., and K. J. A. McCullagh. Effects of exercise on lactate transport into mouse skeletal muscles. Can. J. Appl. Physiol. 19: 275-285, 1994.
3. Carpenter, L., R. C. Poole, and A. P. Halestrap. Cloning and sequencing of the monocarboxylate transporter from mouse Ehrlich-Lettre tumour cells confirms its identity as MCT1 and demonstrates that glycosylation is not required for MCT1 function. Biochim. Biophys. Acta 1279: 157-163, 1996.
4. Deuticke, B. Monocarboxylate transport in erythrocytes. J. Membr. Biol. 173: 300-329, 1989.
5. Garcia, C. K., M. S. Brown, R. K. Pathak, and J. L. Goldstein. cDNA cloning of MCT2, a second monocarboxylate transporter expressed in different cells than MCT1. J. Biol. Chem. 270: 1843-1849, 1995.
6. Garcia, C. K., J. L. Goldstein, R. K. Pathak, G. W. Anderson, and M. S. Brown. Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle. Cell 76: 865-873, 1994.
7. +-ATPase content of low-frequency-stimulated rabbit muscle. FEES Lett. 310: 129-131, 1993.
8. Jóhannsson, E., K. J. A. McCullagh, X.-X. Han, P. K. Fernando, J. Jensen, H. A. Dahl, and A. Bonen. Effect of overexpressing GLUT-1 and GLUT-4 on insulin- and contraction-stimulated glucose transport in muscle. Am. J. Physiol. 271 (Endocrinol. Metab. 34): E547-E555, 1996.
9. Juel, C. Muscle lactate transport studied in sarcolemmal giant vesicles. Biochim. Biophys. Acta 1065: 15-20, 1991.
10. Juel, C. Regulation of cellular pH in skeletal muscle fiber types, studied with sarcolemmal giant vesicles obtained from rat muscles. Biochim. Biophys. Acta 1265: 127-132, 1995.
11. Juel, C., A. Honig, and H. Pilegaard. Muscle lactate transport studied in sarcolemmal giant vesicles: dependence on fiber type and age. Acta Physiol. Scand. 143: 361-365, 1991.
12. Kahn, B. B. Facilitative glucose transporters: regulatory mechanisms and dysregulation in diabetes. J. Clin. Invest. 89: 1367-1374, 1992.
13. Kong, X., J. Manchester, S. Salmons, and J. C. Lawrence. Glucose transporters in single skeletal muscle fibres. J. Biol. Chem. 269: 12963-12967, 1994.