-
1
-
-
85047688069
-
Inflammatory bowel disease: Progress and current concepts of etiopathogenesis
-
10.1111/j.1751-2980.2007.00310.x 1:CAS:528:DC%2BD2sXhsVCnurjK 17970872
-
F Scaldaferri C Fiocchi 2007 Inflammatory bowel disease: progress and current concepts of etiopathogenesis J Dig Dis 8 171 178 10.1111/j.1751-2980. 2007.00310.x 1:CAS:528:DC%2BD2sXhsVCnurjK 17970872
-
(2007)
J Dig Dis
, vol.8
, pp. 171-178
-
-
Scaldaferri, F.1
Fiocchi, C.2
-
2
-
-
7044274559
-
Inflammatory bowel disease: Autoimmune or immune-mediated pathogenesis?
-
10.1080/17402520400004201 15559364
-
Z Wen C Fiocchi 2004 Inflammatory bowel disease: autoimmune or immune-mediated pathogenesis? Clin Dev Immunol 11 195 204 10.1080/ 17402520400004201 15559364
-
(2004)
Clin Dev Immunol
, vol.11
, pp. 195-204
-
-
Wen, Z.1
Fiocchi, C.2
-
3
-
-
0031613754
-
Colonic proteinases: Increased activity in patients with ulcerative colitis
-
1:CAS:528:DyaK1cXltlegs7o%3D
-
D Bustos G Negri JA De Paula CM Di V Yapur A Facente, et al. 1998 Colonic proteinases: increased activity in patients with ulcerative colitis Medicina (B Aires) 58 262 264 1:CAS:528:DyaK1cXltlegs7o%3D
-
(1998)
Medicina (B Aires)
, vol.58
, pp. 262-264
-
-
Bustos, D.1
Negri, G.2
De Paula, J.A.3
Di, C.M.4
Yapur, V.5
Facente, A.6
-
4
-
-
0036840275
-
Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2
-
1:CAS:528:DC%2BD38XptV2gtbc%3D 12414536
-
N Cenac AM Coelho C Nguyen S Compton P ndrade-Gordon WK MacNaughton, et al. 2002 Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2 Am J Pathol 161 1903 1915 1:CAS:528: DC%2BD38XptV2gtbc%3D 12414536
-
(2002)
Am J Pathol
, vol.161
, pp. 1903-1915
-
-
Cenac, N.1
Coelho, A.M.2
Nguyen, C.3
Compton, S.4
Ndrade-Gordon, P.5
MacNaughton, W.K.6
-
5
-
-
0037446646
-
Proteinase-activated receptor-2-induced colonic inflammation in mice: Possible involvement of afferent neurons, nitric oxide, and paracellular permeability
-
1:CAS:528:DC%2BD3sXislersLw%3D 12682265
-
N Cenac R Garcia-Villar L Ferrier M Larauche N Vergnolle NW Bunnett, et al. 2003 Proteinase-activated receptor-2-induced colonic inflammation in mice: possible involvement of afferent neurons, nitric oxide, and paracellular permeability J Immunol 170 4296 4300 1:CAS:528:DC%2BD3sXislersLw%3D 12682265
-
(2003)
J Immunol
, vol.170
, pp. 4296-4300
-
-
Cenac, N.1
Garcia-Villar, R.2
Ferrier, L.3
Larauche, M.4
Vergnolle, N.5
Bunnett, N.W.6
-
6
-
-
25444440807
-
Proteinase-activated receptor-1 is an anti-inflammatory signal for colitis mediated by a type 2 immune response
-
10.1097/01.mib.0000177506.71784.bd 16116312
-
N Cenac L Cellars M Steinhoff P ndrade-Gordon MD Hollenberg JL Wallace, et al. 2005 Proteinase-activated receptor-1 is an anti-inflammatory signal for colitis mediated by a type 2 immune response Inflamm Bowel Dis 11 792 798 10.1097/01.mib.0000177506.71784.bd 16116312
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 792-798
-
-
Cenac, N.1
Cellars, L.2
Steinhoff, M.3
Ndrade-Gordon, P.4
Hollenberg, M.D.5
Wallace, J.L.6
-
7
-
-
0035923526
-
Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis
-
10.1073/pnas.241377298 1:CAS:528:DC%2BD3MXovVynur4%3D 11717450
-
S Fiorucci A Mencarelli B Palazzetti E Distrutti N Vergnolle MD Hollenberg, et al. 2001 Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis Proc Natl Acad Sci USA 98 13936 13941 10.1073/pnas.241377298 1:CAS:528: DC%2BD3MXovVynur4%3D 11717450
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13936-13941
-
-
Fiorucci, S.1
Mencarelli, A.2
Palazzetti, B.3
Distrutti, E.4
Vergnolle, N.5
Hollenberg, M.D.6
-
8
-
-
0035120812
-
Release of mast cell tryptase from human colorectal mucosa in inflammatory bowel disease
-
10.1080/003655201750065933 1:CAS:528:DC%2BD3MXhtlKnsrs%3D 11252410
-
M Raithel S Winterkamp A Pacurar P Ulrich J Hochberger EG Hahn 2001 Release of mast cell tryptase from human colorectal mucosa in inflammatory bowel disease Scand J Gastroenterol 36 174 179 10.1080/003655201750065933 1:CAS:528:DC%2BD3MXhtlKnsrs%3D 11252410
-
(2001)
Scand J Gastroenterol
, vol.36
, pp. 174-179
-
-
Raithel, M.1
Winterkamp, S.2
Pacurar, A.3
Ulrich, P.4
Hochberger, J.5
Hahn, E.G.6
-
9
-
-
13444249470
-
Proteinase-activated receptors: Transducers of proteinase-mediated signaling in inflammation and immune response
-
10.1210/er.2003-0025 1:CAS:528:DC%2BD2MXitFyktrc%3D 15689571
-
M Steinhoff J Buddenkotte V Shpacovitch A Rattenholl C Moormann N Vergnolle, et al. 2005 Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response Endocr Rev 26 1 43 10.1210/er.2003-0025 1:CAS:528:DC%2BD2MXitFyktrc%3D 15689571
-
(2005)
Endocr Rev
, vol.26
, pp. 1-43
-
-
Steinhoff, M.1
Buddenkotte, J.2
Shpacovitch, V.3
Rattenholl, A.4
Moormann, C.5
Vergnolle, N.6
-
10
-
-
43049093678
-
Proteinase-activated receptors (PARs) in infection and inflammation in the gut
-
10.1016/j.biocel.2008.01.016 1:CAS:528:DC%2BD1cXlslGluro%3D 18313348
-
N Vergnolle 2008 Proteinase-activated receptors (PARs) in infection and inflammation in the gut Int J Biochem Cell Biol 40 1219 1227 10.1016/j.biocel.2008.01.016 1:CAS:528:DC%2BD1cXlslGluro%3D 18313348
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 1219-1227
-
-
Vergnolle, N.1
-
11
-
-
33645654546
-
Neutrophil and pathogen proteinases versus proteinase-activated receptor-2 lung epithelial cells: More terminators than activators
-
10.1165/rcmb.2005-0250TR 1:CAS:528:DC%2BD28XjsFCqurs%3D 16547194
-
M Chignard D Pidard 2006 Neutrophil and pathogen proteinases versus proteinase-activated receptor-2 lung epithelial cells: more terminators than activators Am J Respir Cell Mol Biol 34 394 398 10.1165/rcmb.2005-0250TR 1:CAS:528:DC%2BD28XjsFCqurs%3D 16547194
-
(2006)
Am J Respir Cell Mol Biol
, vol.34
, pp. 394-398
-
-
Chignard, M.1
Pidard, D.2
-
12
-
-
0037372534
-
Proteinase-activated receptor-2 and human lung epithelial cells: Disarming by neutrophil serine proteinases
-
10.1165/rcmb.4908 1:CAS:528:DC%2BD3sXhvVOmsLc%3D 12594060
-
S Dulon C Cande NW Bunnett MD Hollenberg M Chignard D Pidard 2003 Proteinase-activated receptor-2 and human lung epithelial cells: disarming by neutrophil serine proteinases Am J Respir Cell Mol Biol 28 339 346 10.1165/rcmb.4908 1:CAS:528:DC%2BD3sXhvVOmsLc%3D 12594060
-
(2003)
Am J Respir Cell Mol Biol
, vol.28
, pp. 339-346
-
-
Dulon, S.1
Cande, C.2
Bunnett, N.W.3
Hollenberg, M.D.4
Chignard, M.5
Pidard, D.6
-
13
-
-
18244404006
-
Pseudomonas aeruginosa elastase disables proteinase-activated receptor 2 in respiratory epithelial cells
-
10.1165/rcmb.2004-0274OC 1:CAS:528:DC%2BD2MXktVCgtbc%3D 15705968
-
S Dulon D Leduc GS Cottrell J D'Alayer KK Hansen NW Bunnett, et al. 2005 Pseudomonas aeruginosa elastase disables proteinase-activated receptor 2 in respiratory epithelial cells Am J Respir Cell Mol Biol 32 411 419 10.1165/rcmb.2004-0274OC 1:CAS:528:DC%2BD2MXktVCgtbc%3D 15705968
-
(2005)
Am J Respir Cell Mol Biol
, vol.32
, pp. 411-419
-
-
Dulon, S.1
Leduc, D.2
Cottrell, G.S.3
D'Alayer, J.4
Hansen, K.K.5
Bunnett, N.W.6
-
14
-
-
0029786481
-
Mechanisms of desensitization and resensitization of proteinase-activated receptor-2
-
10.1074/jbc.271.36.22003 1:CAS:528:DyaK28XlsFKns7k%3D 8703006
-
SK Bohm LM Khitin EF Grady G Aponte DG Payan NW Bunnett 1996 Mechanisms of desensitization and resensitization of proteinase-activated receptor-2 J Biol Chem 271 22003 22016 10.1074/jbc.271.36.22003 1:CAS:528:DyaK28XlsFKns7k%3D 8703006
-
(1996)
J Biol Chem
, vol.271
, pp. 22003-22016
-
-
Bohm, S.K.1
Khitin, L.M.2
Grady, E.F.3
Aponte, G.4
Payan, D.G.5
Bunnett, N.W.6
-
15
-
-
0345004978
-
Thrombin and mast cell tryptase regulate guinea-pig myenteric neurons through proteinase-activated receptors-1 and -2
-
10.1111/j.1469-7793.1999.0741s.x 1:CAS:528:DyaK1MXksVejtLs%3D 10358115
-
CU Corvera O Dery K McConalogue P Gamp M Thoma B Al-Ani, et al. 1999 Thrombin and mast cell tryptase regulate guinea-pig myenteric neurons through proteinase-activated receptors-1 and -2 J Physiol 517 Pt 3 741 756 10.1111/j.1469-7793.1999.0741s.x 1:CAS:528:DyaK1MXksVejtLs%3D 10358115
-
(1999)
J Physiol
, vol.517
, Issue.PART 3
, pp. 741-756
-
-
Corvera, C.U.1
Dery, O.2
McConalogue, K.3
Gamp, P.4
Thoma, M.5
Al-Ani, B.6
-
17
-
-
27744480379
-
Expression of proteinase-activated receptor 2 on human primary gastrointestinal myofibroblasts and stimulation of prostaglandin synthesis
-
10.1139/y05-046 1:CAS:528:DC%2BD2MXhtFygsLzF 16091786
-
ML Seymour DG Binion SJ Compton MD Hollenberg WK MacNaughton 2005 Expression of proteinase-activated receptor 2 on human primary gastrointestinal myofibroblasts and stimulation of prostaglandin synthesis Can J Physiol Pharmacol 83 605 616 10.1139/y05-046 1:CAS:528:DC%2BD2MXhtFygsLzF 16091786
-
(2005)
Can J Physiol Pharmacol
, vol.83
, pp. 605-616
-
-
Seymour, M.L.1
Binion, D.G.2
Compton, S.J.3
Hollenberg, M.D.4
MacNaughton, W.K.5
-
18
-
-
19544392708
-
Clinical relevance of proteinase activated receptors (pars) in the gut
-
10.1136/gut.2004.048876 1:CAS:528:DC%2BD2MXltlOmtrw%3D 15888798
-
N Vergnolle 2005 Clinical relevance of proteinase activated receptors (pars) in the gut Gut 54 867 874 10.1136/gut.2004.048876 1:CAS:528: DC%2BD2MXltlOmtrw%3D 15888798
-
(2005)
Gut
, vol.54
, pp. 867-874
-
-
Vergnolle, N.1
-
19
-
-
4444377666
-
PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways
-
10.1113/jphysiol.2004.061721 1:CAS:528:DC%2BD2cXntFertLY%3D 15194744
-
N Cenac AC Chin R Garcia-Villar C Salvador-Cartier L Ferrier N Vergnolle, et al. 2004 PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways J Physiol 558 913 925 10.1113/jphysiol.2004.061721 1:CAS:528:DC%2BD2cXntFertLY%3D 15194744
-
(2004)
J Physiol
, vol.558
, pp. 913-925
-
-
Cenac, N.1
Chin, A.C.2
Garcia-Villar, R.3
Salvador-Cartier, C.4
Ferrier, L.5
Vergnolle, N.6
-
20
-
-
33847342529
-
Role for protease activity in visceral pain in irritable bowel syndrome
-
10.1172/JCI29255 1:CAS:528:DC%2BD2sXis12ht7o%3D 17304351
-
N Cenac CN Andrews M Holzhausen K Chapman G Cottrell P ndrade-Gordon, et al. 2007 Role for protease activity in visceral pain in irritable bowel syndrome J Clin Invest 117 636 647 10.1172/JCI29255 1:CAS:528:DC%2BD2sXis12ht7o%3D 17304351
-
(2007)
J Clin Invest
, vol.117
, pp. 636-647
-
-
Cenac, N.1
Andrews, C.N.2
Holzhausen, M.3
Chapman, K.4
Cottrell, G.5
Ndrade-Gordon, P.6
-
21
-
-
0032971765
-
Protease-activated receptors mediate apamin-sensitive relaxation of mouse and guinea pig gastrointestinal smooth muscle
-
10.1016/S0016-5085(99)70180-0 1:CAS:528:DyaK1MXhvVOnt7s%3D 10029617
-
TM Cocks V Sozzi JD Moffatt S Selemidis 1999 Protease-activated receptors mediate apamin-sensitive relaxation of mouse and guinea pig gastrointestinal smooth muscle Gastroenterology 116 586 592 10.1016/S0016-5085(99)70180-0 1:CAS:528:DyaK1MXhvVOnt7s%3D 10029617
-
(1999)
Gastroenterology
, vol.116
, pp. 586-592
-
-
Cocks, T.M.1
Sozzi, V.2
Moffatt, J.D.3
Selemidis, S.4
-
22
-
-
0034595060
-
Activation of protease-activated receptor-2 (PAR-2) triggers mucin secretion in the rat sublingual gland
-
10.1006/bbrc.2000.2404 1:CAS:528:DC%2BD3cXhvFCmu7c%3D 10733943
-
A Kawabata N Morimoto H Nishikawa R Kuroda Y Oda K Kakehi 2000 Activation of protease-activated receptor-2 (PAR-2) triggers mucin secretion in the rat sublingual gland Biochem Biophys Res Commun 270 298 302 10.1006/bbrc.2000.2404 1:CAS:528:DC%2BD3cXhvFCmu7c%3D 10733943
-
(2000)
Biochem Biophys Res Commun
, vol.270
, pp. 298-302
-
-
Kawabata, A.1
Morimoto, N.2
Nishikawa, H.3
Kuroda, R.4
Oda, Y.5
Kakehi, K.6
-
23
-
-
0034983372
-
The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection
-
10.1172/JCI10806 1:CAS:528:DC%2BD3MXktFynt7c%3D 11390426
-
A Kawabata M Kinoshita H Nishikawa R Kuroda M Nishida H Araki, et al. 2001 The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection J Clin Invest 107 1443 1450 10.1172/JCI10806 1:CAS:528:DC%2BD3MXktFynt7c%3D 11390426
-
(2001)
J Clin Invest
, vol.107
, pp. 1443-1450
-
-
Kawabata, A.1
Kinoshita, M.2
Nishikawa, H.3
Kuroda, R.4
Nishida, M.5
Araki, H.6
-
24
-
-
67049115841
-
Protease-activated receptor-2 stimulates intestinal epithelial chloride transport through activation of PLC and selective PKC isoforms
-
10.1152/ajpgi.90425.2008 19359428
-
JQ van der Merwe F Moreau WK MacNaughton 2009 Protease-activated receptor-2 stimulates intestinal epithelial chloride transport through activation of PLC and selective PKC isoforms Am J Physiol Gastrointest Liver Physiol 296 6 G1258 G1266 10.1152/ajpgi.90425.2008 19359428
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.296
, Issue.6
-
-
Van Der Merwe, J.Q.1
Moreau, F.2
MacNaughton, W.K.3
-
25
-
-
0032560576
-
Proteinase-activated receptor 2 (PAR2)-activating peptides: Identification of a receptor distinct from PAR2 that regulates intestinal transport
-
10.1073/pnas.95.13.7766 1:CAS:528:DyaK1cXktFCgsLo%3D 9636225
-
N Vergnolle WK MacNaughton B Al-Ani M Saifeddine JL Wallace MD Hollenberg 1998 Proteinase-activated receptor 2 (PAR2)-activating peptides: identification of a receptor distinct from PAR2 that regulates intestinal transport Proc Natl Acad Sci USA 95 7766 7771 10.1073/pnas.95.13.7766 1:CAS:528:DyaK1cXktFCgsLo%3D 9636225
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7766-7771
-
-
Vergnolle, N.1
MacNaughton, W.K.2
Al-Ani, B.3
Saifeddine, M.4
Wallace, J.L.5
Hollenberg, M.D.6
-
26
-
-
33745714789
-
Protective effect of proteinase-activated receptor 2 activation on motility impairment and tissue damage induced by intestinal ischemia/reperfusion in rodents
-
10.2353/ajpath.2006.051098 1:CAS:528:DC%2BD28XnslSntLo%3D 16816371
-
F Cattaruzza N Cenac E Barocelli M Impicciatore E Hyun N Vergnolle, et al. 2006 Protective effect of proteinase-activated receptor 2 activation on motility impairment and tissue damage induced by intestinal ischemia/reperfusion in rodents Am J Pathol 169 177 188 10.2353/ajpath.2006.051098 1:CAS:528:DC%2BD28XnslSntLo%3D 16816371
-
(2006)
Am J Pathol
, vol.169
, pp. 177-188
-
-
Cattaruzza, F.1
Cenac, N.2
Barocelli, E.3
Impicciatore, M.4
Hyun, E.5
Vergnolle, N.6
-
27
-
-
0141727806
-
Colitis induced by proteinase-activated receptor-2 agonists is mediated by a neurogenic mechanism
-
10.1139/y03-080 1:CAS:528:DC%2BD3sXntlKlt78%3D 14614531
-
C Nguyen AM Coelho E Grady SJ Compton JL Wallace MD Hollenberg, et al. 2003 Colitis induced by proteinase-activated receptor-2 agonists is mediated by a neurogenic mechanism Can J Physiol Pharmacol 81 920 927 10.1139/y03-080 1:CAS:528:DC%2BD3sXntlKlt78%3D 14614531
-
(2003)
Can J Physiol Pharmacol
, vol.81
, pp. 920-927
-
-
Nguyen, C.1
Coelho, A.M.2
Grady, E.3
Compton, S.J.4
Wallace, J.L.5
Hollenberg, M.D.6
-
28
-
-
0032708759
-
Proteinase-activated receptor-2-activating peptides induce leukocyte rolling, adhesion, and extravasation in vivo
-
1:CAS:528:DyaK1MXmvFajur4%3D 10528212
-
N Vergnolle 1999 Proteinase-activated receptor-2-activating peptides induce leukocyte rolling, adhesion, and extravasation in vivo J Immunol 163 5064 5069 1:CAS:528:DyaK1MXmvFajur4%3D 10528212
-
(1999)
J Immunol
, vol.163
, pp. 5064-5069
-
-
Vergnolle, N.1
-
29
-
-
50249124682
-
Protease-activated receptor-2 activation: A major actor in intestinal inflammation
-
10.1136/gut.2008.150722 1:CAS:528:DC%2BD1cXhtFKisr7N 18460552
-
E Hyun P Andrade-Gordon M Steinhoff N Vergnolle 2008 Protease-activated receptor-2 activation: a major actor in intestinal inflammation Gut 57 1222 1229 10.1136/gut.2008.150722 1:CAS:528:DC%2BD1cXhtFKisr7N 18460552
-
(2008)
Gut
, vol.57
, pp. 1222-1229
-
-
Hyun, E.1
Andrade-Gordon, P.2
Steinhoff, M.3
Vergnolle, N.4
-
30
-
-
34247631655
-
Inducible nitric oxide synthase from bone marrow-derived cells plays a critical role in regulating colonic inflammation
-
10.1053/j.gastro.2007.01.032 1:CAS:528:DC%2BD2sXmsVyms7g%3D 17449036
-
PL Beck Y Li J Wong CW Chen CM Keenan KA Sharkey, et al. 2007 Inducible nitric oxide synthase from bone marrow-derived cells plays a critical role in regulating colonic inflammation Gastroenterology 132 1778 1790 10.1053/j.gastro.2007.01.032 1:CAS:528:DC%2BD2sXmsVyms7g%3D 17449036
-
(2007)
Gastroenterology
, vol.132
, pp. 1778-1790
-
-
Beck, P.L.1
Li, Y.2
Wong, J.3
Chen, C.W.4
Keenan, C.M.5
Sharkey, K.A.6
-
31
-
-
0029258419
-
Kinetics of white blood cell staining by intravascular administration of rhodamine 6G
-
10.1159/000178955 1:CAS:528:DyaK2MXpsVSqsLw%3D 8655257
-
H Baatz M Steinbauer AG Harris F Krombach 1995 Kinetics of white blood cell staining by intravascular administration of rhodamine 6G Int J Microcirc Clin Exp 15 85 91 10.1159/000178955 1:CAS:528:DyaK2MXpsVSqsLw%3D 8655257
-
(1995)
Int J Microcirc Clin Exp
, vol.15
, pp. 85-91
-
-
Baatz, H.1
Steinbauer, M.2
Harris, A.G.3
Krombach, F.4
-
32
-
-
0033783628
-
VCAM-1, but not ICAM-1 or MAdCAM-1, immunoblockade ameliorates DSS-induced colitis in mice
-
1:CAS:528:DC%2BD3cXnvV2ksrg%3D 11045571
-
A Soriano A Salas A Salas M Sans M Gironella M Elena, et al. 2000 VCAM-1, but not ICAM-1 or MAdCAM-1, immunoblockade ameliorates DSS-induced colitis in mice Lab Invest 80 1541 1551 1:CAS:528:DC%2BD3cXnvV2ksrg%3D 11045571
-
(2000)
Lab Invest
, vol.80
, pp. 1541-1551
-
-
Soriano, A.1
Salas, A.2
Salas, A.3
Sans, M.4
Gironella, M.5
Elena, M.6
-
33
-
-
0032792955
-
Characterization of the inflammatory response to proteinase-activated receptor-2 (PAR2)-activating peptides in the rat paw
-
10.1038/sj.bjp.0702634 1:CAS:528:DyaK1MXkvVKqt7w%3D 10455252
-
N Vergnolle MD Hollenberg KA Sharkey JL Wallace 1999 Characterization of the inflammatory response to proteinase-activated receptor-2 (PAR2)-activating peptides in the rat paw Br J Pharmacol 127 1083 1090 10.1038/sj.bjp.0702634 1:CAS:528:DyaK1MXkvVKqt7w%3D 10455252
-
(1999)
Br J Pharmacol
, vol.127
, pp. 1083-1090
-
-
Vergnolle, N.1
Hollenberg, M.D.2
Sharkey, K.A.3
Wallace, J.L.4
-
34
-
-
0033545627
-
A protective role for protease-activated receptors in the airways
-
10.1038/18223 1:CAS:528:DyaK1MXhvFKisLY%3D 10086357
-
TM Cocks B Fong JM Chow GP Anderson AG Frauman RG Goldie, et al. 1999 A protective role for protease-activated receptors in the airways Nature 398 156 160 10.1038/18223 1:CAS:528:DyaK1MXhvFKisLY%3D 10086357
-
(1999)
Nature
, vol.398
, pp. 156-160
-
-
Cocks, T.M.1
Fong, B.2
Chow, J.M.3
Anderson, G.P.4
Frauman, A.G.5
Goldie, R.G.6
-
35
-
-
0036014824
-
Protease-activated receptor-2 activating peptide SLIGRL inhibits bacterial lipopolysaccharide-induced recruitment of polymorphonuclear leukocytes into the airways of mice
-
1:CAS:528:DC%2BD38XkslWqsrs%3D 12034566
-
JD Moffatt KL Jeffrey TM Cocks 2002 Protease-activated receptor-2 activating peptide SLIGRL inhibits bacterial lipopolysaccharide-induced recruitment of polymorphonuclear leukocytes into the airways of mice Am J Respir Cell Mol Biol 26 680 684 1:CAS:528:DC%2BD38XkslWqsrs%3D 12034566
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 680-684
-
-
Moffatt, J.D.1
Jeffrey, K.L.2
Cocks, T.M.3
-
36
-
-
33645509877
-
Differential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMP
-
10.1182/blood-2004-07-2698 1:CAS:528:DC%2BD28XjtlKlu74%3D 16332977
-
JH Cleator WQ Zhu DE Vaughan HE Hamm 2006 Differential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMP Blood 107 2736 2744 10.1182/blood-2004-07- 2698 1:CAS:528:DC%2BD28XjtlKlu74%3D 16332977
-
(2006)
Blood
, vol.107
, pp. 2736-2744
-
-
Cleator, J.H.1
Zhu, W.Q.2
Vaughan, D.E.3
Hamm, H.E.4
-
37
-
-
0030741026
-
Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2
-
10.1073/pnas.94.16.8884 1:CAS:528:DyaK2sXltlWhtL8%3D 9238072
-
W Kong K McConalogue LM Khitin MD Hollenberg DG Payan SK Bohm, et al. 1997 Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2 Proc Natl Acad Sci USA 94 8884 8889 10.1073/pnas.94.16.8884 1:CAS:528:DyaK2sXltlWhtL8%3D 9238072
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8884-8889
-
-
Kong, W.1
McConalogue, K.2
Khitin, L.M.3
Hollenberg, M.D.4
Payan, D.G.5
Bohm, S.K.6
-
38
-
-
33750492571
-
Activation of mouse protease-activated receptor-2 induces lymphocyte adhesion and generation of reactive oxygen species
-
10.1038/sj.bjp.0706905 1:CAS:528:DC%2BD28XhtFeru7vP 16981001
-
SY Lim GM Tennant S Kennedy CL Wainwright KA Kane 2006 Activation of mouse protease-activated receptor-2 induces lymphocyte adhesion and generation of reactive oxygen species Br J Pharmacol 149 591 599 10.1038/sj.bjp.0706905 1:CAS:528:DC%2BD28XhtFeru7vP 16981001
-
(2006)
Br J Pharmacol
, vol.149
, pp. 591-599
-
-
Lim, S.Y.1
Tennant, G.M.2
Kennedy, S.3
Wainwright, C.L.4
Kane, K.A.5
-
39
-
-
0035575784
-
Trypsin induces activation and inflammatory mediator release from human eosinophils through protease-activated receptor-2
-
1:CAS:528:DC%2BD3MXovVChs7w%3D 11714832
-
S Miike AS McWilliam H Kita 2001 Trypsin induces activation and inflammatory mediator release from human eosinophils through protease-activated receptor-2 J Immunol 167 6615 6622 1:CAS:528:DC%2BD3MXovVChs7w%3D 11714832
-
(2001)
J Immunol
, vol.167
, pp. 6615-6622
-
-
Miike, S.1
McWilliam, A.S.2
Kita, H.3
-
40
-
-
3442880113
-
Agonists of proteinase-activated receptor-2 modulate human neutrophil cytokine secretion, expression of cell adhesion molecules, and migration within 3-D collagen lattices
-
10.1189/jlb.0503221 1:CAS:528:DC%2BD2cXmtlKrsLw%3D 15155775
-
VM Shpacovitch G Varga A Strey M Gunzer F Mooren J Buddenkotte, et al. 2004 Agonists of proteinase-activated receptor-2 modulate human neutrophil cytokine secretion, expression of cell adhesion molecules, and migration within 3-D collagen lattices J Leukoc Biol 76 388 398 10.1189/jlb.0503221 1:CAS:528:DC%2BD2cXmtlKrsLw%3D 15155775
-
(2004)
J Leukoc Biol
, vol.76
, pp. 388-398
-
-
Shpacovitch, V.M.1
Varga, G.2
Strey, A.3
Gunzer, M.4
Mooren, F.5
Buddenkotte, J.6
-
41
-
-
55549136709
-
PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells
-
10.1016/j.bbrc.2008.10.018 1:CAS:528:DC%2BD1cXhtlykt7nL 18854173
-
Y Tanaka F Sekiguchi H Hong A Kawabata 2008 PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells Biochem Biophys Res Commun 377 622 626 10.1016/j.bbrc.2008.10.018 1:CAS:528:DC%2BD1cXhtlykt7nL 18854173
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 622-626
-
-
Tanaka, Y.1
Sekiguchi, F.2
Hong, H.3
Kawabata, A.4
-
42
-
-
0031004878
-
Enhanced leukocyte binding by intestinal microvascular endothelial cells in inflammatory bowel disease
-
10.1053/gast.1997.v112.pm9178682 1:STN:280:DyaK2szit1Shug%3D%3D 9178682
-
DG Binion GA West K Ina NP Ziats SN Emancipator C Fiocchi 1997 Enhanced leukocyte binding by intestinal microvascular endothelial cells in inflammatory bowel disease Gastroenterology 112 1895 1907 10.1053/gast.1997.v112.pm9178682 1:STN:280:DyaK2szit1Shug%3D%3D 9178682
-
(1997)
Gastroenterology
, vol.112
, pp. 1895-1907
-
-
Binion, D.G.1
West, G.A.2
Ina, K.3
Ziats, N.P.4
Emancipator, S.N.5
Fiocchi, C.6
-
43
-
-
0034788785
-
Intestinal permeability is increased in a proportion of spouses of patients with Crohn's disease
-
10.1111/j.1572-0241.2001.04684.x 1:STN:280:DC%2BD3MnjvVWqsg%3D%3D 11693329
-
NP Breslin C Nash RJ Hilsden NB Hershfield LM Price JB Meddings, et al. 2001 Intestinal permeability is increased in a proportion of spouses of patients with Crohn's disease Am J Gastroenterol 96 2934 2938 10.1111/j.1572-0241.2001. 04684.x 1:STN:280:DC%2BD3MnjvVWqsg%3D%3D 11693329
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 2934-2938
-
-
Breslin, N.P.1
Nash, C.2
Hilsden, R.J.3
Hershfield, N.B.4
Price, L.M.5
Meddings, J.B.6
-
44
-
-
0035010386
-
Neurotransmitter coding of enteric neurones in the submucous plexus is changed in non-inflamed rectum of patients with Crohn's disease
-
10.1046/j.1365-2982.2001.00265.x 1:STN:280:DC%2BD3MznvFOqsQ%3D%3D 11437988
-
J Schneider EC Jehle MJ Starlinger M Neunlist K Michel S Hoppe, et al. 2001 Neurotransmitter coding of enteric neurones in the submucous plexus is changed in non-inflamed rectum of patients with Crohn's disease Neurogastroenterol Motil 13 255 264 10.1046/j.1365-2982.2001.00265.x 1:STN:280:DC%2BD3MznvFOqsQ%3D%3D 11437988
-
(2001)
Neurogastroenterol Motil
, vol.13
, pp. 255-264
-
-
Schneider, J.1
Jehle, E.C.2
Starlinger, M.J.3
Neunlist, M.4
Michel, K.5
Hoppe, S.6
-
45
-
-
0034974997
-
Quantitative comparison of growth-associated protein-43 and substance P in ulcerative colitis
-
1:CAS:528:DC%2BD3MXksFeqtLs%3D 11373321
-
P Vento T Kiviluoto U Keranen HJ Jarvinen E Kivilaakso S Soinila 2001 Quantitative comparison of growth-associated protein-43 and substance P in ulcerative colitis J Histochem Cytochem 49 749 758 1:CAS:528: DC%2BD3MXksFeqtLs%3D 11373321
-
(2001)
J Histochem Cytochem
, vol.49
, pp. 749-758
-
-
Vento, P.1
Kiviluoto, T.2
Keranen, U.3
Jarvinen, H.J.4
Kivilaakso, E.5
Soinila, S.6
-
46
-
-
0037258839
-
Mucosal T cells as a target for treatment of IBD
-
1:CAS:528:DC%2BD3sXjtlelurw%3D 12698871
-
M Watanabe M Yamazaki T Kanai 2003 Mucosal T cells as a target for treatment of IBD J Gastroenterol 38 Suppl 15 48 50 1:CAS:528: DC%2BD3sXjtlelurw%3D 12698871
-
(2003)
J Gastroenterol
, vol.38
, Issue.SUPPL. 15
, pp. 48-50
-
-
Watanabe, M.1
Yamazaki, M.2
Kanai, T.3
-
47
-
-
0034547916
-
Delayed onset of inflammation in protease-activated receptor-2-deficient mice
-
1:CAS:528:DC%2BD3cXosFOhsLg%3D 11086091
-
JR Lindner ML Kahn SR Coughlin GR Sambrano E Schauble D Bernstein, et al. 2000 Delayed onset of inflammation in protease-activated receptor-2-deficient mice J Immunol 165 6504 6510 1:CAS:528:DC%2BD3cXosFOhsLg%3D 11086091
-
(2000)
J Immunol
, vol.165
, pp. 6504-6510
-
-
Lindner, J.R.1
Kahn, M.L.2
Coughlin, S.R.3
Sambrano, G.R.4
Schauble, E.5
Bernstein, D.6
-
48
-
-
0018945027
-
Naturally occurring antibodies directed to TNBS-modified cell surface but not the trinitrophenyl moiety
-
1:STN:280:DyaL3M%2Fgsl2kuw%3D%3D 7410849
-
ZK Ballas RC Kuppers 1980 Naturally occurring antibodies directed to TNBS-modified cell surface but not the trinitrophenyl moiety J Immunol 125 1644 1649 1:STN:280:DyaL3M%2Fgsl2kuw%3D%3D 7410849
-
(1980)
J Immunol
, vol.125
, pp. 1644-1649
-
-
Ballas, Z.K.1
Kuppers, R.C.2
-
49
-
-
35348982262
-
Mouse models of inflammatory bowel disease
-
10.1016/j.addr.2007.07.003 1:CAS:528:DC%2BD2sXht1ams7fI 17825455
-
S Wirtz MF Neurath 2007 Mouse models of inflammatory bowel disease Adv Drug Deliv Rev 59 1073 1083 10.1016/j.addr.2007.07.003 1:CAS:528: DC%2BD2sXht1ams7fI 17825455
-
(2007)
Adv Drug Deliv Rev
, vol.59
, pp. 1073-1083
-
-
Wirtz, S.1
Neurath, M.F.2
-
50
-
-
0029791910
-
Effects of dextran sulphate sodium on intestinal epithelial cells and intestinal lymphocytes
-
10.1136/gut.39.2.234 1:CAS:528:DyaK28XlvVOlu70%3D 8991862
-
J Ni SF Chen D Hollander 1996 Effects of dextran sulphate sodium on intestinal epithelial cells and intestinal lymphocytes Gut 39 234 241 10.1136/gut.39.2.234 1:CAS:528:DyaK28XlvVOlu70%3D 8991862
-
(1996)
Gut
, vol.39
, pp. 234-241
-
-
Ni, J.1
Chen, S.F.2
Hollander, D.3
-
51
-
-
15644376138
-
Selective depletion of neutrophils by a monoclonal antibody, RP-3, suppresses dextran sulphate sodium-induced colitis in rats
-
10.1111/j.1440-1746.1997.tb00375.x 1:CAS:528:DyaK1cXhvVyltbc%3D 9504889
-
M Natsui K Kawasaki H Takizawa SI Hayashi Y Matsuda K Sugimura, et al. 1997 Selective depletion of neutrophils by a monoclonal antibody, RP-3, suppresses dextran sulphate sodium-induced colitis in rats J Gastroenterol Hepatol 12 801 808 10.1111/j.1440-1746.1997.tb00375.x 1:CAS:528: DyaK1cXhvVyltbc%3D 9504889
-
(1997)
J Gastroenterol Hepatol
, vol.12
, pp. 801-808
-
-
Natsui, M.1
Kawasaki, K.2
Takizawa, H.3
Hayashi, S.I.4
Matsuda, Y.5
Sugimura, K.6
-
52
-
-
0027933817
-
Role of intestinal microflora in chronic inflammation and ulceration of the rat colon
-
10.1136/gut.35.8.1090 1:STN:280:DyaK2M%2FhtFOguw%3D%3D 7926912
-
S Videla J Vilaseca F Guarner A Salas F Treserra E Crespo, et al. 1994 Role of intestinal microflora in chronic inflammation and ulceration of the rat colon Gut 35 1090 1097 10.1136/gut.35.8.1090 1:STN:280:DyaK2M%2FhtFOguw%3D%3D 7926912
-
(1994)
Gut
, vol.35
, pp. 1090-1097
-
-
Videla, S.1
Vilaseca, J.2
Guarner, F.3
Salas, A.4
Treserra, F.5
Crespo, E.6
-
53
-
-
0035514524
-
Cell adhesion molecules, leukocyte trafficking, and strategies to reduce leukocyte infiltration
-
1:STN:280:DC%2BD38%2FovVKjsA%3D%3D 11817056
-
ZA Radi ME Kehrli Jr MR Ackermann 2001 Cell adhesion molecules, leukocyte trafficking, and strategies to reduce leukocyte infiltration J Vet Intern Med 15 516 529 1:STN:280:DC%2BD38%2FovVKjsA%3D%3D 11817056
-
(2001)
J Vet Intern Med
, vol.15
, pp. 516-529
-
-
Radi, Z.A.1
Kehrli Jr., M.E.2
Ackermann, M.R.3
-
54
-
-
34548230927
-
Getting to the site of inflammation: The leukocyte adhesion cascade updated
-
10.1038/nri2156 1:CAS:528:DC%2BD2sXpsV2qtb0%3D 17717539
-
K Ley C Laudanna MI Cybulsky S Nourshargh 2007 Getting to the site of inflammation: the leukocyte adhesion cascade updated Nat Rev Immunol 7 678 689 10.1038/nri2156 1:CAS:528:DC%2BD2sXpsV2qtb0%3D 17717539
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 678-689
-
-
Ley, K.1
Laudanna, C.2
Cybulsky, M.I.3
Nourshargh, S.4
-
55
-
-
29244458849
-
Blocking MAdCAM-1 in vivo reduces leukocyte extravasation and reverses chronic inflammation in experimental colitis
-
10.1007/s00384-004-0709-y 15856265
-
S Farkas M Hornung C Sattler K Edtinger M Steinbauer M Anthuber, et al. 2006 Blocking MAdCAM-1 in vivo reduces leukocyte extravasation and reverses chronic inflammation in experimental colitis Int J Colorectal Dis 21 71 78 10.1007/s00384-004-0709-y 15856265
-
(2006)
Int J Colorectal Dis
, vol.21
, pp. 71-78
-
-
Farkas, S.1
Hornung, M.2
Sattler, C.3
Edtinger, K.4
Steinbauer, M.5
Anthuber, M.6
-
56
-
-
0032793928
-
Inhibition of dextran sulphate sodium (DSS)-induced colitis in mice by intracolonically administered antibodies against adhesion molecules (endothelial leucocyte adhesion molecule-1 (ELAM-1) or intercellular adhesion molecule-1 (ICAM-1))
-
10.1046/j.1365-2249.1999.00985.x 1:CAS:528:DyaK1MXmtV2ku7c%3D 10469048
-
N Hamamoto K Maemura I Hirata M Murano S Sasaki K Katsu 1999 Inhibition of dextran sulphate sodium (DSS)-induced colitis in mice by intracolonically administered antibodies against adhesion molecules (endothelial leucocyte adhesion molecule-1 (ELAM-1) or intercellular adhesion molecule-1 (ICAM-1)) Clin Exp Immunol 117 462 468 10.1046/j.1365-2249.1999.00985.x 1:CAS:528: DyaK1MXmtV2ku7c%3D 10469048
-
(1999)
Clin Exp Immunol
, vol.117
, pp. 462-468
-
-
Hamamoto, N.1
Maemura, K.2
Hirata, I.3
Murano, M.4
Sasaki, S.5
Katsu, K.6
-
57
-
-
0033063325
-
VCAM-1 and ICAM-1 mediate leukocyte-endothelial cell adhesion in rat experimental colitis
-
10.1016/S0016-5085(99)70070-3 1:CAS:528:DyaK1MXisVSls7o%3D 10092309
-
M Sans J Panes E Ardite JI Elizalde Y Arce M Elena, et al. 1999 VCAM-1 and ICAM-1 mediate leukocyte-endothelial cell adhesion in rat experimental colitis Gastroenterology 116 874 883 10.1016/S0016-5085(99)70070-3 1:CAS:528:DyaK1MXisVSls7o%3D 10092309
-
(1999)
Gastroenterology
, vol.116
, pp. 874-883
-
-
Sans, M.1
Panes, J.2
Ardite, E.3
Elizalde, J.I.4
Arce, Y.5
Elena, M.6
-
58
-
-
0029148532
-
Anti-CD11b/CD18 antibodies reduce inflammation in acute colitis in rats
-
1:CAS:528:DyaK2MXosVGis7s%3D 7648720
-
MJ Palmen CD Dijkstra MB van der Ende AS Pena EP Van Rees 1995 Anti-CD11b/CD18 antibodies reduce inflammation in acute colitis in rats Clin Exp Immunol 101 351 356 1:CAS:528:DyaK2MXosVGis7s%3D 7648720
-
(1995)
Clin Exp Immunol
, vol.101
, pp. 351-356
-
-
Palmen, M.J.1
Dijkstra, C.D.2
Van Der Ende, M.B.3
Pena, A.S.4
Van Rees, E.P.5
-
59
-
-
0141817942
-
Proinflammatory role of proteinase-activated receptor-2 in humans and mice during cutaneous inflammation in vivo
-
10.1096/fj.02-1112com 1:CAS:528:DC%2BD3sXot1Kmsbw%3D 14519665
-
S Seeliger CK Derian N Vergnolle NW Bunnett R Nawroth M Schmelz, et al. 2003 Proinflammatory role of proteinase-activated receptor-2 in humans and mice during cutaneous inflammation in vivo FASEB J 17 1871 1885 10.1096/fj.02-1112com 1:CAS:528:DC%2BD3sXot1Kmsbw%3D 14519665
-
(2003)
FASEB J
, vol.17
, pp. 1871-1885
-
-
Seeliger, S.1
Derian, C.K.2
Vergnolle, N.3
Bunnett, N.W.4
Nawroth, R.5
Schmelz, M.6
-
60
-
-
34247229838
-
Membrane-type serine protease-1/matriptase induces interleukin-6 and -8 in endothelial cells by activation of protease-activated receptor-2: Potential implications in atherosclerosis
-
10.1161/01.ATV.0000258862.61067.14 1:CAS:528:DC%2BD2sXislCrsrs%3D 17255532
-
I Seitz S Hess H Schulz R Eckl G Busch HP Montens, et al. 2007 Membrane-type serine protease-1/matriptase induces interleukin-6 and -8 in endothelial cells by activation of protease-activated receptor-2: potential implications in atherosclerosis Arterioscler Thromb Vasc Biol 27 769 775 10.1161/01.ATV.0000258862.61067.14 1:CAS:528:DC%2BD2sXislCrsrs%3D 17255532
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 769-775
-
-
Seitz, I.1
Hess, S.2
Schulz, H.3
Eckl, R.4
Busch, G.5
Montens, H.P.6
-
61
-
-
15744405106
-
Autologous hematopoietic stem cell transplantation in patients with refractory Crohn's disease
-
10.1053/j.gastro.2004.11.051 15765390
-
Y Oyama RM Craig AE Traynor K Quigley L Statkute A Halverson, et al. 2005 Autologous hematopoietic stem cell transplantation in patients with refractory Crohn's disease Gastroenterology 128 552 563 10.1053/j.gastro.2004.11.051 15765390
-
(2005)
Gastroenterology
, vol.128
, pp. 552-563
-
-
Oyama, Y.1
Craig, R.M.2
Traynor, A.E.3
Quigley, K.4
Statkute, L.5
Halverson, A.6
-
62
-
-
0037372443
-
High-dose immune suppression and autologous hematopoietic stem cell transplantation in refractory Crohn disease
-
10.1182/blood-2002-07-2122 1:CAS:528:DC%2BD3sXhslCrurw%3D 12393477
-
RK Burt A Traynor Y Oyama R Craig 2003 High-dose immune suppression and autologous hematopoietic stem cell transplantation in refractory Crohn disease Blood 101 2064 2066 10.1182/blood-2002-07-2122 1:CAS:528:DC%2BD3sXhslCrurw%3D 12393477
-
(2003)
Blood
, vol.101
, pp. 2064-2066
-
-
Burt, R.K.1
Traynor, A.2
Oyama, Y.3
Craig, R.4
|