Autologous hematopoietic stem cell transplantation in patients with refractory Crohn's disease

Gastroenterology

Volumn 128, Issue 3, 2005, Pages 552-563

  Oyama, Yu ^a,b   Craig, Robert M ^a   Traynor, Ann E ^a   Quigley, Kathleen ^a   Statkute, Laisvyde ^a   Halverson, Amy ^a   Brush, Mary ^a   Verda, Larissa ^a   Kowalska, Barbara ^a   Krosnjar, Nela ^a   Kletzel, Morris ^a   Whitington, Peter F ^a   Burt, Richard K ^a  

^a NORTHWESTERN UNIVERSITY MEDICAL CENTER   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CIPROFLOXACIN; CORTICOSTEROID; COTRIMOXAZOLE; CYCLOPHOSPHAMIDE; FLUCONAZOLE; GRANULOCYTE COLONY STIMULATING FACTOR; INFLIXIMAB; MESNA; METHYLPREDNISOLONE; METRONIDAZOLE; PENTAMIDINE; PIPERACILLIN PLUS TAZOBACTAM; THYMOCYTE ANTIBODY; VALACICLOVIR;

ADULT; AGED; ANOREXIA; ARTICLE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; BACTERIAL INFECTION; CLINICAL ARTICLE; CLINICAL TRIAL; COLON RADIOGRAPHY; COLONOSCOPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROHN DISEASE; CYTOMEGALOVIRUS INFECTION; CYTOPENIA; DIARRHEA; DISEASE ACTIVITY; FEBRILE NEUTROPENIA; FEMALE; FEVER; FOLLOW UP; GASTROENTERITIS; HEMATEMESIS; HEMORRHAGIC CYSTITIS; HOSPITAL DISCHARGE; HUMAN; MALE; MYCOSIS; MYELOABLATIVE CONDITIONING; NAUSEA AND VOMITING; NEUTROPHIL; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; REMISSION; SERUM SICKNESS; SIDE EFFECT; STEM CELL MOBILIZATION; SYMPTOM; THROMBOCYTE; TREATMENT OUTCOME; UPPER RESPIRATORY TRACT INFECTION; VIRUS INFECTION; ADOLESCENT; HEMATOPOIETIC STEM CELL TRANSPLANTATION; PATHOPHYSIOLOGY; PHASE 1 CLINICAL TRIAL; PILOT STUDY; RECURRENT DISEASE; SURVIVAL;

ADOLESCENT; ADULT; CROHN DISEASE; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MALE; PILOT PROJECTS; RECURRENCE; REMISSION INDUCTION; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 15744405106     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2004.11.051     Document Type: Article

References (32)

1. S.S. Rao, P.A. Cann, C.D. Holdsworth Clinical experience of the tolerance of mesalazine and olsalazine in patients intolerant of sulfasalazine Scand J Gastroenterol 22 1987 332 336
2. L.H. Bernstein, M.S. Frank, L.J. Brandt, S.J. Boley Healing of perianal Crohn's disease with metronidazole Gastroenterology 79 1980 357 365
3. D.H. Present, B.I. Korelitz, N. Wisch, J.L. Glass, D.B. Sachar, B.S. Pasternack Treatment of Crohn's disease with 6-mercaptopurine. A long-term, randomized, double-blinded study N Engl J Med 302 1980 981 987
4. J. Markowitz, K. Grancher, N. Kohn, M. Lesser, F. Daum A multicenter trial of 6-mercaptopurine and prednisone in children with newly diagnosed Crohn's disease Gastroenterology 119 2000 895 902
5. J.M. Willoughby, J. Beckett, P.J. Kumar, A.M. Dawson Controlled trial of azathioprine in Crohn's disease Lancet 2 1971 944 947
6. R.A. Kozarek, D.J. Patterson, M.D. Gelfand, V.A. Botoman, T.J. Ball, K.R. Wilske Methotrexate induces clinical and histologic remission in patients with refractory inflammatory bowel disease Ann Intern Med 110 1989 353 356
7. J. Brynskov, L. Freund, S.N. Rasmussen, K. Lauritsen, O.S. de Muckadell, N. Williams, A.S. MacDonald, R. Tanton, F. Molina, M.C. Campanini A placebo-controlled, double-blinded randomized trial of cyclosporine therapy in active chronic Crohn's disease N Engl J Med 321 1989 845 850
8. W.J. Sandborn, D.H. Present, K.L. Isaacs, D.C. Wolf, E. Greenberg, S.B. Hanauer, B.G. Feagan, L. Mayer, T. Johnson, J. Galanko, C. Martin, R.S. Sandler Tacrolimus for the treatment in patients with Crohn's disease; a randomized, placebo-controlled trial Gastroenterology 125 2003 380 388
9. A. Stollmach, B.M. Wittig, C. Moser, J. Fischinger, R. Duchmann, M. Zeitz Safety and efficacy of intravenous pulse cyclophosphamide in acute steroid refractory inflammatory bowel disease Gut 52 2003 377 382
10. D.H. Present, P. Rutgeerts, S. Targan, S.B. Hanauer, L. Mayer, R.A. van Hogezand, D.K. Podolsky, B.E. Sands, T. Braakman, K.L. DeWoody, T.F. Schaible, S.J. van Deventer Infliximab for the treatment of fistulas in patients with Crohn's disease N Engl J Med 340 1999 1398 1405
11. R.G. Farmer, G. Whelan, V.W. Fazio Long-term follow-up of patients with Crohn's disease. Relationship of the clinical pattern and prognosis Gastroenterology 88 1985 1818 1827
12. A. Lapidus, O. Bernell, G. Hellers, R. Lofberg Clinical course of colorectal Crohn's disease a 35-year follow up study of 507 patients Gastroenterology 114 1998 1151 1160
13. E.V. Loftus Jr, M.D. Silverstein, W.J. Sandborn, W.J. Tremaine, W.S. Harmsen, A.R. Zinsmeister Crohn's disease in Olmsted county, Minnesota, 1940-1993 incidence, prevalence, and survival Gastroenterology 114 1998 1161 1168
14. P.G. Persson, O. Bernell, C.E. Leijonmarck, B.Y. Farahmand, G. Hellers, A. Ahlbom Survival and cause-specific mortality in inflammatory bowel disease a population-based cohort study Gastroenterology 110 1996 1339 1345
15. T. Jess, K.V. Winther, P. Munkholm, E. Langholz, V. Binder Mortality and causes of death in Crohn's disease follow-up of a population-based cohort in Copenhagen County, Denmark Gastroenterology 122 2002 1808 1814
16. R.K. Burt, A. Traynor, Y. Oyama, R. Craig High dose immune suppression and autologous hematopoietic stem cell transplantation in refractory Crohn's disease Blood 101 2003 2064 2066
17. W.R. Best, J.M. Becktel, J.W. Singleton, F. Kern Jr. Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study Gastroenterology 70 1976 439 444
18. R.M. Craig, A. Traynor, Y. Oyama, R.K. Burt Hematopoietic stem cell transplantation for severe Crohn's disease Bone Marrow Transplant 32 2003 S57 S59
19. R.M. Craig Autologous hematopoietic stem cell transplantation for Crohn's disease Autoimmune Rev 1 2002 244 249
20. E.J. Irvine, B. Feagan, J. Rochon, A. Archambault, R.N. Fedorak, A. Groll, D. Kinnear, F. Saibil, J.W.D. McDonald Quality of life a valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease Gastroenterology 106 1994 287 296
21. G. Guyatt, A. Mitchell, E.J. Irvine, J. Singer, H. Williams, R. Goodacre, C. Tompkins A new measure of health status for clinical trials in inflammatory bowel disease Gastroenterology 96 1989 804 810
22. R. Kuhn, J. Lohler, D. Rennick, K. Rajewsky, W. Muller Interleukin-10-deficient mice develop chronic enterocolitis Cell 75 1993 263 274
23. R.O. Ehrhardt, B. Ludviksson Induction of colitis in IL2-deficient-mice the role of thymic and peripheral dysregulation in the generation of autoreactive T-cells Res Immunol 148 1997 582 588
24. A.B. Kulkarni, J.M. Ward, L. Yaswen, C.L. Mackall, S.R. Bauer, C.G. Huh, R.E. Gress, S. Karlsson Transforming growth factor-beta 1 null mice. An animal model for inflammatory disorders Am J Pathol 146 1995 264 275
25. N. Inohara, G. Nunez The NOD a signaling module that regulates apoptosis and host defense against pathogens Oncogene 20 2001 6473 6481
26. Y. Ogura, D.K. Bonen, N. Inohara, D.L. Nicolae, F.F. Chen, R. Ramos, H. Britton, T. Moran, R. Karaliuskas, R.H. Duerr, J.P. Achkar, S.R. Brant, T.M. Bayless, B.S. Kirschner, S.B. Hanauer, G. Nunez, J.H. Cho A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease Nature 411 2001 603 606
27. A.P. Cuthbert, S.A. Fisher, M.M. Mirza, K. King, J. Hampe, P.J. Croucher, S. Mascheretti, J. Sanderson, A. Forbes, J. Mansfield, S. Schreiber, C.M. Lewis, C.G. Mathew The combination of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease Gastroenterology 122 2002 867 874
28. S.O. Lopez-Cubero, K.M. Sullivan, G.B. McDonald Course of Crohn's disease after allogeneic marrow transplantation Gastroenterology 114 1998 433 440
29. P.E. Drakos, A. Nagler, R. Or Case of Crohn's disease in bone marrow transplantation Am J Hematol 43 1993 157 158
30. A. Kashyap, S.J. Forman Autologous bone marrow transplantation for non-Hodgkin's lymphoma resulting in long-term remission of coincidental Crohn's disease Br J Haematol 103 1998 651 652
31. J. Castro, H.L. Bentch, L. Smith, S. Kalter, C. Bachier, C. Meneghatti, A. Moore, S. Oliversen, C.F. LeMaistre Prolonged clinical remission in patients with inflammatory bowel disease after high dose chemotherapy and autologous blood stem cell transplantation (abstr) Blood 88 Suppl 1 1996 133a
32. Y. Oyama, A. Traynor, R. Craig, W. Barr, R. Rosa, R. Burt Treatment related mortality (TRM) and overall mortality (OM) in patients undergoing autologous hematopoietic stem cell transplantation (HSCT) for autoimmune diseases, a single center experience (abstr) Blood 102 Suppl 1 2003 986a