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Volumn 299, Issue 2, 2010, Pages

Inhibition of acinar apoptosis occurs during acute pancreatitis in the human homologue ΔF508 cystic fibrosis mouse

Author keywords

Experimental pancreatitis; Inflammation

Indexed keywords

CASPASE 3; CERULETIDE; MYELOPEROXIDASE;

EID: 77955593691     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00061.2010     Document Type: Article
Times cited : (12)

References (86)
  • 1
    • 0038298386 scopus 로고    scopus 로고
    • Molecular consequences of cystic fibrosis transmembrane regulator (CFTR) gene mutations in the exocrine pancreas
    • DOI 10.1136/gut.52.8.1159
    • Ahmed N, Corey M, Forstner G, Zielenski J, Tsui LC, Ellis L, Tullis E, Durie P. Molecular consequences of cystic fibrosis transmembrane regulator (CFTR) gene mutations in the exocrine pancreas. Gut 52: 1159-1164, 2003. (Pubitemid 36877429)
    • (2003) Gut , vol.52 , Issue.8 , pp. 1159-1164
    • Ahmed, N.1    Corey, M.2    Forstner, G.3    Zielenski, J.4    Tsui, L.-C.5    Ellis, L.6    Tullis, E.7    Durie, P.8
  • 5
    • 0037305183 scopus 로고    scopus 로고
    • Diminished lung injury with vascular adhesion molecule-1 blockade in choline-deficient ethionine diet-induced pancreatitis
    • Callicutt CS, Sabek O, Fukatsu K, Lundberg AH, Gaber L, Wilcox H, Kotb M, Gaber AO. Diminished lung injury with vascular adhesion molecule-1 blockade in choline-deficient ethionine diet-induced pancreatitis. Surgery 133: 186-196, 2003.
    • (2003) Surgery , vol.133 , pp. 186-196
    • Callicutt, C.S.1    Sabek, O.2    Fukatsu, K.3    Lundberg, A.H.4    Gaber, L.5    Wilcox, H.6    Kotb, M.7    Gaber, A.O.8
  • 6
    • 0041701380 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa-induced apoptosis is defective in respiratory epithelial cells expressing mutant cystic fibrosis transmembrane conductance regulator
    • Cannon CL, Kowalski MP, Stopak KS, Pier GB. Pseudomonas aeruginosa-induced apoptosis is defective in respiratory epithelial cells expressing mutant cystic fibrosis transmembrane conductance regulator. Am J Respir Cell Mol Biol 29: 188-197, 2003.
    • (2003) Am J Respir Cell Mol Biol , vol.29 , pp. 188-197
    • Cannon, C.L.1    Kowalski, M.P.2    Stopak, K.S.3    Pier, G.B.4
  • 15
    • 23244433449 scopus 로고    scopus 로고
    • A proinflammatory, antiapoptotic phenotype underlies the susceptibility to acute pancreatitis in cystic fibrosis transmembrane regulator (-/-) mice
    • DiMagno MJ, Lee SH, Hao Y, Zhou SY, McKenna BJ, Owyang C. A proinflammatory, antiapoptotic phenotype underlies the susceptibility to acute pancreatitis in cystic fibrosis transmembrane regulator (-/-) mice. Gastroenterology 129: 665-681, 2005.
    • (2005) Gastroenterology , vol.129 , pp. 665-681
    • DiMagno, M.J.1    Lee, S.H.2    Hao, Y.3    Zhou, S.Y.4    McKenna, B.J.5    Owyang, C.6
  • 18
    • 0042564511 scopus 로고    scopus 로고
    • Postmitochondrial regulation of apoptosis by bicarbonate
    • Dong Z, Wang J, Zhong Q. Postmitochondrial regulation of apoptosis by bicarbonate. Exp Cell Res 288: 301-312, 2003.
    • (2003) Exp Cell Res , vol.288 , pp. 301-312
    • Dong, Z.1    Wang, J.2    Zhong, Q.3
  • 19
    • 34250714931 scopus 로고    scopus 로고
    • Association of pancreas divisum and recurrent acute pancreatitis with the IVS8-5T-12TG allele of the CFTR gene and CFTR dysfunction
    • Dray X, Fajac I, Bienvenu T, Chryssostalis A, Sogni P, Hubert D. Association of pancreas divisum and recurrent acute pancreatitis with the IVS8-5T-12TG allele of the CFTR gene and CFTR dysfunction. Pancreas 35: 90-93, 2007.
    • (2007) Pancreas , vol.35 , pp. 90-93
    • Dray, X.1    Fajac, I.2    Bienvenu, T.3    Chryssostalis, A.4    Sogni, P.5    Hubert, D.6
  • 20
    • 1642277855 scopus 로고    scopus 로고
    • Characteristic multiorgan pathology of cystic fibrosis in a long-living cystic fibrosis transmembrane regulator knockout murine model
    • Durie PR, Kent G, Phillips MJ, Ackerley CA. Characteristic multiorgan pathology of cystic fibrosis in a long-living cystic fibrosis transmembrane regulator knockout murine model. Am J Pathol 164: 1481-1493, 2004.
    • (2004) Am J Pathol , vol.164 , pp. 1481-1493
    • Durie, P.R.1    Kent, G.2    Phillips, M.J.3    Ackerley, C.A.4
  • 22
    • 72449150930 scopus 로고    scopus 로고
    • Neutrophil apoptosis: A target for enhancing the resolution of inflammation
    • Filep JG, El Kebir D. Neutrophil apoptosis: a target for enhancing the resolution of inflammation. J Cell Biochem 108: 1039-1046, 2009.
    • (2009) J Cell Biochem , vol.108 , pp. 1039-1046
    • Filep, J.G.1    El Kebir, D.2
  • 24
    • 0034787415 scopus 로고    scopus 로고
    • Pancreatic acinar cell dysfunction in CFTR(-/-) mice is associated with impairments in luminal pH and endocytosis
    • Freedman SD, Kern HF, Scheele GA. Pancreatic acinar cell dysfunction in CFTR(-/-) mice is associated with impairments in luminal pH and endocytosis. Gastroenterology 121: 950-957, 2001.
    • (2001) Gastroenterology , vol.121 , pp. 950-957
    • Freedman, S.D.1    Kern, H.F.2    Scheele, G.A.3
  • 27
    • 0029983188 scopus 로고    scopus 로고
    • Mutant cystic fibrosis transmembrane conductance regulator inhibits acidification and apoptosis in C127 cells: Possible relevance to cystic fibrosis
    • Gottlieb RA, Dosanjh A. Mutant cystic fibrosis transmembrane conductance regulator inhibits acidification and apoptosis in C127 cells: possible relevance to cystic fibrosis. Proc Natl Acad Sci USA 93: 3587-3591, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3587-3591
    • Gottlieb, R.A.1    Dosanjh, A.2
  • 29
    • 67049172475 scopus 로고    scopus 로고
    • Defective organellar acidification as a cause of cystic fibrosis lung disease: Reexamination of a recurring hypothesis
    • Haggie PM, Verkman AS. Defective organellar acidification as a cause of cystic fibrosis lung disease: reexamination of a recurring hypothesis. Am J Physiol Lung Cell Mol Physiol 296: L859-L867, 2009.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.296
    • Haggie, P.M.1    Verkman, A.S.2
  • 30
    • 1642512653 scopus 로고    scopus 로고
    • Antagonizing XIAP-mediated caspase-3 inhibition. Achilles' heel of cancers?
    • Huang Y, Lu M, Wu H. Antagonizing XIAP-mediated caspase-3 inhibition. Achilles' heel of cancers? Cancer Cell 5: 1-2, 2004.
    • (2004) Cancer Cell , vol.5 , pp. 1-2
    • Huang, Y.1    Lu, M.2    Wu, H.3
  • 31
    • 0037008671 scopus 로고    scopus 로고
    • Glutathione levels and BAX activation during apoptosis due to oxidative stress in cells expressing wild-type and mutant cystic fibrosis transmembrane conductance regulator
    • Jungas T, Motta I, Duffieux F, Fanen P, Stoven V, Ojcius DM. Glutathione levels and BAX activation during apoptosis due to oxidative stress in cells expressing wild-type and mutant cystic fibrosis transmembrane conductance regulator. J Biol Chem 277: 27912-27918, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 27912-27918
    • Jungas, T.1    Motta, I.2    Duffieux, F.3    Fanen, P.4    Stoven, V.5    Ojcius, D.M.6
  • 32
    • 0028783295 scopus 로고
    • Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis
    • Kaiser AM, Saluja AK, Sengupta A, Saluja M, Steer ML. Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis. Am J Physiol Cell Physiol 269: C1295-C1304, 1995.
    • (1995) Am J Physiol Cell Physiol , vol.269
    • Kaiser, A.M.1    Saluja, A.K.2    Sengupta, A.3    Saluja, M.4    Steer, M.L.5
  • 33
    • 53949083274 scopus 로고    scopus 로고
    • Air pollution induces enhanced mitochondrial oxidative stress in cystic fibrosis airway epithelium
    • Kamdar O, Le W, Zhang J, Ghio AJ, Rosen GD, Upadhyay D. Air pollution induces enhanced mitochondrial oxidative stress in cystic fibrosis airway epithelium. FEBS Lett 582: 3601-3606, 2008.
    • (2008) FEBS Lett , vol.582 , pp. 3601-3606
    • Kamdar, O.1    Le, W.2    Zhang, J.3    Ghio, A.J.4    Rosen, G.D.5    Upadhyay, D.6
  • 36
    • 0036736893 scopus 로고    scopus 로고
    • CFTR gene mutations in patients suffering from acute pancreatitis
    • Kostuch M, Rudzki S, Semczuk A, Kulczycki L. CFTR gene mutations in patients suffering from acute pancreatitis. Med Sci Monit 8: BR369-BR372, 2002.
    • (2002) Med Sci Monit , vol.8
    • Kostuch, M.1    Rudzki, S.2    Semczuk, A.3    Kulczycki, L.4
  • 39
    • 20044366634 scopus 로고    scopus 로고
    • IRES in distress: Translational regulation of the inhibitor of apoptosis proteins XIAP and HIAP2 during cell stress
    • Lewis SM, Holcik M. IRES in distress: translational regulation of the inhibitor of apoptosis proteins XIAP and HIAP2 during cell stress. Cell Death Differ 12: 547-553, 2005.
    • (2005) Cell Death Differ , vol.12 , pp. 547-553
    • Lewis, S.M.1    Holcik, M.2
  • 40
    • 0036896008 scopus 로고    scopus 로고
    • Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion
    • Ma T, Thiagarajah JR, Yang H, Sonawane ND, Folli C, Galietta LJ, Verkman AS. Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. J Clin Invest 110: 1651-1658, 2002.
    • (2002) J Clin Invest , vol.110 , pp. 1651-1658
    • Ma, T.1    Thiagarajah, J.R.2    Yang, H.3    Sonawane, N.D.4    Folli, C.5    Galietta, L.J.6    Verkman, A.S.7
  • 41
    • 0030926711 scopus 로고    scopus 로고
    • DNA fragmentation is a feature of cystic fibrosis epithelial cells: A disease with inappropriate apoptosis?
    • Maiuri L, Raia V, De Marco G, Coletta S, de Ritis G, Londei M, Auricchio S. DNA fragmentation is a feature of cystic fibrosis epithelial cells: a disease with inappropriate apoptosis? FEBS Lett 408: 225-231, 1997.
    • (1997) FEBS Lett , vol.408 , pp. 225-231
    • Maiuri, L.1    Raia, V.2    De Marco, G.3    Coletta, S.4    De Ritis, G.5    Londei, M.6    Auricchio, S.7
  • 43
    • 0025834174 scopus 로고
    • Localization of the cystic fibrosis transmembrane conductance regulator in pancreas
    • Marino CR, Matovcik LM, Gorelick FS, Cohn JA. Localization of the cystic fibrosis transmembrane conductance regulator in pancreas. J Clin Invest 88: 712-716, 1991.
    • (1991) J Clin Invest , vol.88 , pp. 712-716
    • Marino, C.R.1    Matovcik, L.M.2    Gorelick, F.S.3    Cohn, J.A.4
  • 44
    • 27444439642 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane regulator gene carrier status is a risk factor for young onset pancreatic adenocarcinoma
    • McWilliams R, Highsmith WE, Rabe KG, de Andrade M, Tordsen LA, Holtegaard LM, Petersen GM. Cystic fibrosis transmembrane regulator gene carrier status is a risk factor for young onset pancreatic adenocarcinoma. Gut 54: 1661-1662, 2005.
    • (2005) Gut , vol.54 , pp. 1661-1662
    • McWilliams, R.1    Highsmith, W.E.2    Rabe, K.G.3    De Andrade, M.4    Tordsen, L.A.5    Holtegaard, L.M.6    Petersen, G.M.7
  • 45
    • 77951497702 scopus 로고    scopus 로고
    • In cystic fibrosis homozygotes and heterozygotes, neutrophil apoptosis is delayed and modulated by diamide or roscovitine: Evidence for an innate neutrophil disturbance
    • Moriceau S, Lenoir G, Witko-Sarsat V. In cystic fibrosis homozygotes and heterozygotes, neutrophil apoptosis is delayed and modulated by diamide or roscovitine: evidence for an innate neutrophil disturbance. J Innate Immun 2: 260-266, 2010.
    • (2010) J Innate Immun , vol.2 , pp. 260-266
    • Moriceau, S.1    Lenoir, G.2    Witko-Sarsat, V.3
  • 46
    • 0032770489 scopus 로고    scopus 로고
    • Quantitation of inflammatory responses to bacteria in young cystic fibrosis and control patients
    • Muhlebach MS, Stewart PW, Leigh MW, Noah TL. Quantitation of inflammatory responses to bacteria in young cystic fibrosis and control patients. Am J Respir Crit Care Med 160: 186-191, 1999.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 186-191
    • Muhlebach, M.S.1    Stewart, P.W.2    Leigh, M.W.3    Noah, T.L.4
  • 48
    • 2342448582 scopus 로고    scopus 로고
    • Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database
    • Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller PP, Wang R, Fang X, Guo R, Zhang M, Lippman ME, Yang D, Wang S. Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database. J Med Chem 47: 2430-2440, 2004.
    • (2004) J Med Chem , vol.47 , pp. 2430-2440
    • Nikolovska-Coleska, Z.1    Xu, L.2    Hu, Z.3    Tomita, Y.4    Li, P.5    Roller, P.P.6    Wang, R.7    Fang, X.8    Guo, R.9    Zhang, M.10    Lippman, M.E.11    Yang, D.12    Wang, S.13
  • 49
    • 54349119629 scopus 로고    scopus 로고
    • A pH-sensitive, neurogenic pathway mediates disease severity in a model of post-ERCP pancreatitis
    • Noble MD, Romac J, Vigna SR, Liddle RA. A pH-sensitive, neurogenic pathway mediates disease severity in a model of post-ERCP pancreatitis. Gut 57: 1566-1571, 2008.
    • (2008) Gut , vol.57 , pp. 1566-1571
    • Noble, M.D.1    Romac, J.2    Vigna, S.R.3    Liddle, R.A.4
  • 51
    • 33745063177 scopus 로고    scopus 로고
    • Caerulein-induced acute pancreatitis in mice that constitutively overexpress Reg/PAP genes
    • Norkina O, Graf R, Appenzeller P, De Lisle RC. Caerulein-induced acute pancreatitis in mice that constitutively overexpress Reg/PAP genes. BMC Gastroenterol 6: 16, 2006.
    • (2006) BMC Gastroenterol , vol.6 , pp. 16
    • Norkina, O.1    Graf, R.2    Appenzeller, P.3    De Lisle, R.C.4
  • 59
    • 0028917643 scopus 로고
    • Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease
    • Perez-Sala D, Collado-Escobar D, Mollinedo F. Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease. J Biol Chem 270: 6235-6242, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 6235-6242
    • Perez-Sala, D.1    Collado-Escobar, D.2    Mollinedo, F.3
  • 61
    • 48149106004 scopus 로고    scopus 로고
    • Epithelial cell apoptosis and neutrophil recruitment in acute lung injury - A unifying hypothesis? What we have learned from small interfering RNAs
    • Perl M, Lomas-Neira J, Chung CS, Ayala A. Epithelial cell apoptosis and neutrophil recruitment in acute lung injury - a unifying hypothesis? What we have learned from small interfering RNAs. Mol Med 14: 465-475, 2008.
    • (2008) Mol Med , vol.14 , pp. 465-475
    • Perl, M.1    Lomas-Neira, J.2    Chung, C.S.3    Ayala, A.4
  • 65
    • 34548480193 scopus 로고    scopus 로고
    • Exaggerated apoptosis and NF-kappaB activation in pancreatic and tracheal cystic fibrosis cells
    • Rottner M, Kunzelmann C, Mergey M, Freyssinet JM, Martinez MC. Exaggerated apoptosis and NF-kappaB activation in pancreatic and tracheal cystic fibrosis cells. FASEB J 21: 2939-2948, 2007.
    • (2007) FASEB J , vol.21 , pp. 2939-2948
    • Rottner, M.1    Kunzelmann, C.2    Mergey, M.3    Freyssinet, J.M.4    Martinez, M.C.5
  • 68
    • 0036597492 scopus 로고    scopus 로고
    • Hereditary pancreatitis: A model for inflammatory diseases of the pancreas
    • Schneider A, Whitcomb DC. Hereditary pancreatitis: a model for inflammatory diseases of the pancreas. Best Pract Res Clin Gastroenterol 16: 347-363, 2002.
    • (2002) Best Pract Res Clin Gastroenterol , vol.16 , pp. 347-363
    • Schneider, A.1    Whitcomb, D.C.2
  • 69
    • 0030224049 scopus 로고    scopus 로고
    • Regulation of neutrophil apoptosis - Its biological significance in inflammation and the immune response
    • Sendo F, Tsuchida H, Takeda Y, Gon S, Takei H, Kato T, Hachiya O, Watanabe H. Regulation of neutrophil apoptosis - its biological significance in inflammation and the immune response. Hum Cell 9: 215-222, 1996.
    • (1996) Hum Cell , vol.9 , pp. 215-222
    • Sendo, F.1    Tsuchida, H.2    Takeda, Y.3    Gon, S.4    Takei, H.5    Kato, T.6    Hachiya, O.7    Watanabe, H.8
  • 73
    • 0035920126 scopus 로고    scopus 로고
    • X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes
    • Suzuki Y, Nakabayashi Y, Nakata K, Reed JC, Takahashi R. X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes. J Biol Chem 276: 27058-27063, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 27058-27063
    • Suzuki, Y.1    Nakabayashi, Y.2    Nakata, K.3    Reed, J.C.4    Takahashi, R.5
  • 74
    • 20444377309 scopus 로고    scopus 로고
    • Significance of apoptotic cell death in systemic complications with severe acute pancreatitis
    • Takeyama Y. Significance of apoptotic cell death in systemic complications with severe acute pancreatitis. J Gastroenterol 40: 1-10, 2005.
    • (2005) J Gastroenterol , vol.40 , pp. 1-10
    • Takeyama, Y.1
  • 77
    • 0141706392 scopus 로고    scopus 로고
    • Extracellular matrix proteins protect pancreatic cancer cells from death via mitochondrial and nonmitochondrial pathways
    • Vaquero EC, Edderkaoui M, Nam KJ, Gukovsky I, Pandol SJ, Gukovskaya AS. Extracellular matrix proteins protect pancreatic cancer cells from death via mitochondrial and nonmitochondrial pathways. Gastroenterology 125: 1188-1202, 2003.
    • (2003) Gastroenterology , vol.125 , pp. 1188-1202
    • Vaquero, E.C.1    Edderkaoui, M.2    Nam, K.J.3    Gukovsky, I.4    Pandol, S.J.5    Gukovskaya, A.S.6
  • 80
    • 69249095455 scopus 로고    scopus 로고
    • Can too much acid sour your pancreas?
    • Williams JA, DiMagno MJ. Can too much acid sour your pancreas? Gastroenterology 137: 779-782, 2009.
    • (2009) Gastroenterology , vol.137 , pp. 779-782
    • Williams, J.A.1    DiMagno, M.J.2
  • 81
  • 84
    • 4644313798 scopus 로고    scopus 로고
    • Interleukin 8 secretion from monocytes of subjects heterozygous for the deltaF508 cystic fibrosis transmembrane conductance regulator gene mutation is altered
    • Zaman MM, Gelrud A, Junaidi O, Regan MM, Warny M, Shea JC, Kelly C, O'Sullivan BP, Freedman SD. Interleukin 8 secretion from monocytes of subjects heterozygous for the deltaF508 cystic fibrosis transmembrane conductance regulator gene mutation is altered. Clin Diagn Lab Immunol 11: 819-824, 2004.
    • (2004) Clin Diagn Lab Immunol , vol.11 , pp. 819-824
    • Zaman, M.M.1    Gelrud, A.2    Junaidi, O.3    Regan, M.M.4    Warny, M.5    Shea, J.C.6    Kelly, C.7    O'Sullivan, B.P.8    Freedman, S.D.9


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