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Volumn 3, Issue 8, 2010, Pages 2362-2379

Rational polytherapy with antiepileptic drugs

Author keywords

Antiepileptic drug; Epilepsy; Rational polytherapy

Indexed keywords

4 AMINOBUTYRIC ACID; ANTICONVULSIVE AGENT; BENZODIAZEPINE DERIVATIVE; CALCIUM CHANNEL; CARBAMAZEPINE; CLONAZEPAM; ETHOSUXIMIDE; ETIRACETAM; FELBAMATE; GABAPENTIN; GLUTAMIC ACID; HARKOSERIDE; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PREGABALIN; RUFINAMIDE; SODIUM CHANNEL; TIAGABINE; TOPIRAMATE; VALPROIC ACID; VIGABATRIN; ZONISAMIDE;

EID: 77955586367     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph3082362     Document Type: Article
Times cited : (53)

References (82)
  • 1
    • 0019349776 scopus 로고
    • Monotherapy or polytherapy for epilepsy?
    • Reynolds, E.H.; Shorvon, S.D. Monotherapy or polytherapy for epilepsy? Epilepsia 1981, 22, 1-10.
    • (1981) Epilepsia , vol.22 , pp. 1-10
    • Reynolds, E.H.1    Shorvon, S.D.2
  • 3
    • 0034598762 scopus 로고    scopus 로고
    • Early identification of refractory epilepsy
    • Kwan, P.; Brodie, M.J. Early identification of refractory epilepsy. N. Engl. J. Med. 2000, 342, 314-319.
    • (2000) N. Engl. J. Med , vol.342 , pp. 314-319
    • Kwan, P.1    Brodie, M.J.2
  • 4
    • 33750045736 scopus 로고    scopus 로고
    • Combination therapy in epilepsy: When and what to use
    • Kwan, P.; Brodie, M.J. Combination therapy in epilepsy: when and what to use. Drugs 2006, 66, 1817-1829.
    • (2006) Drugs , vol.66 , pp. 1817-1829
    • Kwan, P.1    Brodie, M.J.2
  • 5
    • 37349066198 scopus 로고    scopus 로고
    • Pharmacodynamic principles and mechanisms of drug interactions
    • J. Bourgeois, B.F. Patsalos, P. N. Matagne, A. Eds. Cambridge University Press: Cambridge, London, UK
    • Bourgeois, B.F. Pharmacodynamic principles and mechanisms of drug interactions. In Antiepileptic drugs: Combination therapy and interactions, Majkowski, J. Bourgeois, B.F. Patsalos, P. N. Matagne, A. Eds. Cambridge University Press: Cambridge, London, UK, 2005.
    • (2005) Antiepileptic Drugs: Combination Therapy and Interactions, Majkowski
    • Bourgeois, B.F.1
  • 7
    • 0345975882 scopus 로고    scopus 로고
    • Systematic screening allows reduction of adverse antiepileptic drug effects: A randomized trial
    • Gilliam, F.G.; Fessler, A.J.; Baker, G.; Vahle, V.; Carter, J.; Attarian, H. Systematic screening allows reduction of adverse antiepileptic drug effects: a randomized trial. Neurology 2004, 62, 23-27.
    • (2004) Neurology , vol.62 , pp. 23-27
    • Gilliam, F.G.1    Fessler, A.J.2    Baker, G.3    Vahle, V.4    Carter, J.5    Attarian, H.6
  • 8
    • 1642484485 scopus 로고    scopus 로고
    • Epilepsy and bone health in adults
    • Pack, A.M.; Morrell, M.J. Epilepsy and bone health in adults. Epilepsy Behav. 2004, 5 (Suppl. 2), S24-S29.
    • (2004) Epilepsy Behav , vol.5 , Issue.SUPPL. 2
    • Pack, A.M.1    Morrell, M.J.2
  • 10
    • 3042798891 scopus 로고    scopus 로고
    • The neurobiology of antiepileptic drugs
    • Rogawski, M.A.; Loscher, W. The neurobiology of antiepileptic drugs. Nat. Rev. Neurosci. 2004, 5, 553-564.
    • (2004) Nat. Rev. Neurosci , vol.5 , pp. 553-564
    • Rogawski, M.A.1    Loscher, W.2
  • 11
    • 77949415427 scopus 로고    scopus 로고
    • Mechanisms of action of antiepileptic drugs: The search for synergy
    • Stafstrom, C.E. Mechanisms of action of antiepileptic drugs: the search for synergy. Curr. Opin. Neurol. 2007, 23, 157-163.
    • (2007) Curr. Opin. Neurol , vol.23 , pp. 157-163
    • Stafstrom, C.E.1
  • 12
    • 59249102753 scopus 로고    scopus 로고
    • From ion channels to complex networks: Magic bullet versus magic shotgun approaches to anticonvulsant pharmacotherapy
    • Bianchi, M.T.; Pathmanathan, J.; Cash, S.S. From ion channels to complex networks: magic bullet versus magic shotgun approaches to anticonvulsant pharmacotherapy. Med. Hypotheses 2009, 72, 297-305.
    • (2009) Med. Hypotheses , vol.72 , pp. 297-305
    • Bianchi, M.T.1    Pathmanathan, J.2    Cash, S.S.3
  • 14
    • 33847639380 scopus 로고    scopus 로고
    • Synergistic combinations of anticonvulsant agents: What is the evidence from animal experiments?
    • Jonker, D.M.; Voskuyl, R.A.; Danhof, M. Synergistic combinations of anticonvulsant agents: what is the evidence from animal experiments? Epilepsia 2007, 48, 412-434.
    • (2007) Epilepsia , vol.48 , pp. 412-434
    • Jonker, D.M.1    Voskuyl, R.A.2    Danhof, M.3
  • 15
    • 61849098715 scopus 로고    scopus 로고
    • Benefit of combination therapy in epilepsy: A review of the preclinical evidence with levetiracetam
    • Kaminski, R.M.; Matagne, A.; Patsalos, P.N.; Klitgaard, H. Benefit of combination therapy in epilepsy: a review of the preclinical evidence with levetiracetam. Epilepsia 2009, 50, 387-397.
    • (2009) Epilepsia , vol.50 , pp. 387-397
    • Kaminski, R.M.1    Matagne, A.2    Patsalos, P.N.3    Klitgaard, H.4
  • 16
    • 15744394656 scopus 로고    scopus 로고
    • Antiepileptic action induced by a combination of vigabatrin and tiagabine
    • Fueta, Y.; Kunugita, N.; Schwarz, W. Antiepileptic action induced by a combination of vigabatrin and tiagabine. Neuroscience 2005, 132, 335-345.
    • (2005) Neuroscience , vol.132 , pp. 335-345
    • Fueta, Y.1    Kunugita, N.2    Schwarz, W.3
  • 17
    • 0028304171 scopus 로고
    • Synergism with GABAergic drugs in refractory epilepsy
    • Leach, J.P.; Brodie, M.J. Synergism with GABAergic drugs in refractory epilepsy. Lancet 1994, 343, 1650.
    • (1994) Lancet , vol.343 , pp. 1650
    • Leach, J.P.1    Brodie, M.J.2
  • 19
    • 27744434295 scopus 로고    scopus 로고
    • Pregabalin add-on treatment in patients with partial seizures: A novel evaluation of flexible-dose and fixed-dose treatment in a double-blind, placebo-controlled study
    • Elger, C.E.; Brodie, M.J.; Anhut, H.; Lee, C.M.; Barrett, J.A. Pregabalin add-on treatment in patients with partial seizures: a novel evaluation of flexible-dose and fixed-dose treatment in a double-blind, placebo-controlled study. Epilepsia 2005, 46, 1926-1936.
    • (2005) Epilepsia , vol.46 , pp. 1926-1936
    • Elger, C.E.1    Brodie, M.J.2    Anhut, H.3    Lee, C.M.4    Barrett, J.A.5
  • 20
    • 13244277459 scopus 로고    scopus 로고
    • Safety and efficacy of two pregabalin regimens for add-on treatment of partial epilepsy
    • Beydoun, A.; Uthman, B.M.; Kugler, A.R.; Greiner, M.J.; Knapp, L.E.; Garofalo, E.A. Safety and efficacy of two pregabalin regimens for add-on treatment of partial epilepsy. Neurology 2005, 64, 475-480.
    • (2005) Neurology , vol.64 , pp. 475-480
    • Beydoun, A.1    Uthman, B.M.2    Kugler, A.R.3    Greiner, M.J.4    Knapp, L.E.5    Garofalo, E.A.6
  • 21
    • 68949213747 scopus 로고    scopus 로고
    • Rational polytherapy
    • French, J.A.; Faught, E. Rational polytherapy. Epilepsia 2009, 50 (Suppl. 8), 63-68.
    • (2009) Epilepsia , vol.50 , Issue.SUPPL. 8 , pp. 63-68
    • French, J.A.1    Faught, E.2
  • 22
    • 0025142913 scopus 로고
    • Effects of removal of phenytoin, carbamazepine, and valproate on cognitive function
    • Duncan, J.S.; Shorvon, S.D.; Trimble, M.R. Effects of removal of phenytoin, carbamazepine, and valproate on cognitive function. Epilepsia 1990, 31, 584-591.
    • (1990) Epilepsia , vol.31 , pp. 584-591
    • Duncan, J.S.1    Shorvon, S.D.2    Trimble, M.R.3
  • 23
    • 47249146126 scopus 로고    scopus 로고
    • Drug target identification using side-effect similarity
    • Campillos, M.; Kuhn, M.; Gavin, A.C.; Jensen, L.J.; Bork, P. Drug target identification using side-effect similarity. Science 2008, 321, 263-266.
    • (2008) Science , vol.321 , pp. 263-266
    • Campillos, M.1    Kuhn, M.2    Gavin, A.C.3    Jensen, L.J.4    Bork, P.5
  • 24
    • 43149106905 scopus 로고    scopus 로고
    • Progressive anticonvulsant hypersensitivity syndrome associated with change of drug product
    • Sabroe, T.P.; Sabers, A. Progressive anticonvulsant hypersensitivity syndrome associated with change of drug product. Acta Neurol. Scand. 2008, 117, 428-431.
    • (2008) Acta Neurol. Scand , vol.117 , pp. 428-431
    • Sabroe, T.P.1    Sabers, A.2
  • 25
    • 70349484436 scopus 로고    scopus 로고
    • Isobolographic characterization of interactions of levetiracetam with the various antiepileptic drugs in the mouse 6 Hz psychomotor seizure model
    • Wojda, E.; Wlaz, A.; Patsalos, P.N.; Luszczki, J.J. Isobolographic characterization of interactions of levetiracetam with the various antiepileptic drugs in the mouse 6 Hz psychomotor seizure model. Epilepsy Res. 2009, 86, 163-174.
    • (2009) Epilepsy Res , vol.86 , pp. 163-174
    • Wojda, E.1    Wlaz, A.2    Patsalos, P.N.3    Luszczki, J.J.4
  • 26
    • 33749007441 scopus 로고    scopus 로고
    • An overview of drug combination analysis with isobolograms
    • Tallarida, R. J. An overview of drug combination analysis with isobolograms. J. Pharmacol. Exp. Ther. 2006, 319, 1-7.
    • (2006) J. Pharmacol. Exp. Ther , vol.319 , pp. 1-7
    • Tallarida, R.J.1
  • 27
    • 73349086269 scopus 로고    scopus 로고
    • Isobolographic characterization of the anticonvulsant interaction profiles of levetiracetam in combination with clonazepam, ethosuximide, phenobarbital and valproate in the mouse pentylenetetrazole-induced seizure model
    • Dudra-Jastrzebska, M.; Andres-Mach, M.M.; Ratnaraj, N.; Patsalos, P.N.; Czuczwar, S.J.; Luszczki, J.J. Isobolographic characterization of the anticonvulsant interaction profiles of levetiracetam in combination with clonazepam, ethosuximide, phenobarbital and valproate in the mouse pentylenetetrazole-induced seizure model. Seizure 2009, 18, 607-614.
    • (2009) Seizure , vol.18 , pp. 607-614
    • Dudra-Jastrzebska, M.1    Andres-Mach, M.M.2    Ratnaraj, N.3    Patsalos, P.N.4    Czuczwar, S.J.5    Luszczki, J.J.6
  • 28
    • 20344407068 scopus 로고    scopus 로고
    • Synergistic interaction of gabapentin and oxcarbazepine in the mouse maximal electroshock seizure model--an isobolographic analysis
    • Luszczki, J.J.; Andres, M.M.; Czuczwar, S.J. Synergistic interaction of gabapentin and oxcarbazepine in the mouse maximal electroshock seizure model--an isobolographic analysis. Eur. J. Pharmacol. 2005, 515, 54-61.
    • (2005) Eur. J. Pharmacol , vol.515 , pp. 54-61
    • Luszczki, J.J.1    Andres, M.M.2    Czuczwar, S.J.3
  • 29
    • 33645019118 scopus 로고    scopus 로고
    • Pharmacodynamic and pharmacokinetic characterization of interactions between levetiracetam and numerous antiepileptic drugs in the mouse maximal electroshock seizure model: An isobolographic analysis
    • Luszczki, J.J.; Andres, M.M.; Czuczwar, P.; Cioczek-Czuczwar, A.; Ratnaraj, N.; Patsalos, P.N.; Czuczwar, S.J. Pharmacodynamic and pharmacokinetic characterization of interactions between levetiracetam and numerous antiepileptic drugs in the mouse maximal electroshock seizure model: an isobolographic analysis. Epilepsia 2006, 47, 10-20.
    • (2006) Epilepsia , vol.47 , pp. 10-20
    • Luszczki, J.J.1    Andres, M.M.2    Czuczwar, P.3    Cioczek-Czuczwar, A.4    Ratnaraj, N.5    Patsalos, P.N.6    Czuczwar, S.J.7
  • 30
    • 0036713855 scopus 로고    scopus 로고
    • Effect of gabapentin on the anticonvulsant activity of antiepileptic drugs against electroconvulsions in mice: An isobolographic analysis
    • Borowicz, K.K.; Swiader, M.; Luszczki, J.; Czuczwar, S.J. Effect of gabapentin on the anticonvulsant activity of antiepileptic drugs against electroconvulsions in mice: an isobolographic analysis. Epilepsia 2002, 43, 956-963.
    • (2002) Epilepsia , vol.43 , pp. 956-963
    • Borowicz, K.K.1    Swiader, M.2    Luszczki, J.3    Czuczwar, S.J.4
  • 31
    • 67649112797 scopus 로고    scopus 로고
    • Pharmacodynamic interactions between antiepileptic drugs: Preclinical data based on isobolography. Expert Opin. Drug Metab
    • Czuczwar, S.J.; Kaplanski, J.; Swiderska-Dziewit, G.; Gergont, A.; Kroczka, S.; Kacinski, M. Pharmacodynamic interactions between antiepileptic drugs: preclinical data based on isobolography. Expert Opin. Drug Metab. Toxicol. 2009. 5, 131-136
    • (2009) Toxicol , vol.5 , pp. 131-136
    • Czuczwar, S.J.1    Kaplanski, J.2    Swiderska-Dziewit, G.3    Gergont, A.4    Kroczka, S.5    Kacinski, M.6
  • 32
    • 0023780034 scopus 로고
    • Anticonvulsant potency and neurotoxicity of valproate alone and in combination with carbamazepine or phenobarbital
    • Bourgeois, B.F. Anticonvulsant potency and neurotoxicity of valproate alone and in combination with carbamazepine or phenobarbital. Clin. Neuropharmacol. 1988, 11, 348-359.
    • (1988) Clin. Neuropharmacol , vol.11 , pp. 348-359
    • Bourgeois, B.F.1
  • 33
    • 0038045883 scopus 로고    scopus 로고
    • Interactions between oxcarbazepine and conventional antiepileptic drugs in the maximal electroshock test in mice: An isobolographic analysis
    • Luszczki, J.J.; Borowicz, K.K.; Swiader, M.; Czuczwar, S.J. Interactions between oxcarbazepine and conventional antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis. Epilepsia 2003, 44, 489-499.
    • (2003) Epilepsia , vol.44 , pp. 489-499
    • Luszczki, J.J.1    Borowicz, K.K.2    Swiader, M.3    Czuczwar, S.J.4
  • 34
    • 0024239758 scopus 로고
    • Combination of valproate and ethosuximide: Antiepileptic and neurotoxic interaction
    • Bourgeois, B.F. Combination of valproate and ethosuximide: antiepileptic and neurotoxic interaction. J. Pharmacol. Exp. Ther. 1988, 247, 1128-1132.
    • (1988) J. Pharmacol. Exp. Ther , vol.247 , pp. 1128-1132
    • Bourgeois, B.F.1
  • 35
    • 34247096547 scopus 로고    scopus 로고
    • Levetiracetam and felbamate interact both pharmacodynamically and pharmacokinetically: An isobolographic analysis in the mouse maximal electroshock model
    • Luszczki, J.J.; Andres-Mach, M.M.; Ratnaraj, N.; Patsalos, P.N.; Czuczwar, S.J. Levetiracetam and felbamate interact both pharmacodynamically and pharmacokinetically: an isobolographic analysis in the mouse maximal electroshock model. Epilepsia 2007, 48, 806-815.
    • (2007) Epilepsia , vol.48 , pp. 806-815
    • Luszczki, J.J.1    Andres-Mach, M.M.2    Ratnaraj, N.3    Patsalos, P.N.4    Czuczwar, S.J.5
  • 36
    • 13244260783 scopus 로고    scopus 로고
    • Interaction between lamotrigine and felbamate in the maximal electroshock-induced seizures in mice: An isobolographic analysis
    • Luszczki, J.J.; Czuczwar, S.J. Interaction between lamotrigine and felbamate in the maximal electroshock-induced seizures in mice: an isobolographic analysis. Eur. Neuropsychopharmacol 2005, 15, 133-142.
    • (2005) Eur. Neuropsychopharmacol , vol.15 , pp. 133-142
    • Luszczki, J.J.1    Czuczwar, S.J.2
  • 37
    • 4043122635 scopus 로고    scopus 로고
    • Preclinical profile of combinations of some second-generation antiepileptic drugs: An isobolographic analysis
    • Luszczki, J.J.; Czuczwar, S.J. Preclinical profile of combinations of some second-generation antiepileptic drugs: an isobolographic analysis. Epilepsia 2004, 45, 895-907.
    • (2004) Epilepsia , vol.45 , pp. 895-907
    • Luszczki, J.J.1    Czuczwar, S.J.2
  • 38
    • 60349092371 scopus 로고    scopus 로고
    • Pharmacodynamic and pharmacokinetic interaction profiles of levetiracetam in combination with gabapentin, tiagabine and vigabatrin in the mouse pentylenetetrazole-induced seizure model: An isobolographic analysis
    • Dudra-Jastrzebska, M.; Andres-Mach, M.M.; Sielski, M.; Ratnaraj, N.; Patsalos, P.N.; Czuczwar, S.J.; Luszczki, J.J. Pharmacodynamic and pharmacokinetic interaction profiles of levetiracetam in combination with gabapentin, tiagabine and vigabatrin in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis. Eur. J. Pharmacol. 2009, 605, 87-94.
    • (2009) Eur. J. Pharmacol , vol.605 , pp. 87-94
    • Dudra-Jastrzebska, M.1    Andres-Mach, M.M.2    Sielski, M.3    Ratnaraj, N.4    Patsalos, P.N.5    Czuczwar, S.J.6    Luszczki, J.J.7
  • 39
    • 26244452793 scopus 로고    scopus 로고
    • Isobolographic characterisation of interactions among selected newer antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model
    • Luszczki, J.J.; Czuczwar, S.J. Isobolographic characterisation of interactions among selected newer antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model. Naunyn Schmiedebergs Arch. Pharmacol. 2005, 372, 41-54.
    • (2005) Naunyn Schmiedebergs Arch. Pharmacol , vol.372 , pp. 41-54
    • Luszczki, J.J.1    Czuczwar, S.J.2
  • 40
    • 0642308238 scopus 로고    scopus 로고
    • Tiagabine synergistically interacts with gabapentin in the electroconvulsive threshold test in mice
    • Luszczki, J.J.; Swiader, M.; Parada-Turska, J.; Czuczwar, S.J. Tiagabine synergistically interacts with gabapentin in the electroconvulsive threshold test in mice. Neuropsychopharmacology 2003, 28, 1817-1830.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1817-1830
    • Luszczki, J.J.1    Swiader, M.2    Parada-Turska, J.3    Czuczwar, S.J.4
  • 41
    • 33846322231 scopus 로고    scopus 로고
    • Gabapentin synergistically interacts with topiramate in the mouse maximal electroshock seizure model: An isobolographic analysis. Pharmacol
    • Luszczki, J.J.; Czuczwar, S.J. Gabapentin synergistically interacts with topiramate in the mouse maximal electroshock seizure model: an isobolographic analysis. Pharmacol. Rep. 2006, 58, 944-954.
    • (2006) Rep , vol.58 , pp. 944-954
    • Luszczki, J.J.1    Czuczwar, S.J.2
  • 42
    • 52049105361 scopus 로고    scopus 로고
    • Isobolographic and behavioral characterizations of interactions between vigabatrin and gabapentin in two experimental models of epilepsy
    • Luszczki, J.J.; Ratnaraj, N.; Patsalos, P.N.; Czuczwar, S.J. Isobolographic and behavioral characterizations of interactions between vigabatrin and gabapentin in two experimental models of epilepsy. Eur. J. Pharmacol. 2008, 595, 13-21.
    • (2008) Eur. J. Pharmacol , vol.595 , pp. 13-21
    • Luszczki, J.J.1    Ratnaraj, N.2    Patsalos, P.N.3    Czuczwar, S.J.4
  • 43
    • 0042572368 scopus 로고    scopus 로고
    • Interactions of lamotrigine with topiramate and first-generation antiepileptic drugs in the maximal electroshock test in mice: An isobolographic analysis
    • Luszczki, J.J.; Czuczwar, M.; Kis, J.; Krysa, J.; Pasztelan, I.; Swiader, M.; Czuczwar, S.J. Interactions of lamotrigine with topiramate and first-generation antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis. Epilepsia 2003, 44, 1003-1013.
    • (2003) Epilepsia , vol.44 , pp. 1003-1013
    • Luszczki, J.J.1    Czuczwar, M.2    Kis, J.3    Krysa, J.4    Pasztelan, I.5    Swiader, M.6    Czuczwar, S.J.7
  • 44
    • 0019469190 scopus 로고
    • Evidence for a synergistic interaction between phenytoin and phenobarbital in experimental animals
    • Masuda, Y.; Utsui, Y.; Shiraishi, Y.; Karasawa, T.; Yoshida, K.; Shimizu, M. Evidence for a synergistic interaction between phenytoin and phenobarbital in experimental animals. J. Pharmacol. Exp. Ther. 1981, 217, 805-811.
    • (1981) J. Pharmacol. Exp. Ther , vol.217 , pp. 805-811
    • Masuda, Y.1    Utsui, Y.2    Shiraishi, Y.3    Karasawa, T.4    Yoshida, K.5    Shimizu, M.6
  • 45
    • 33846844751 scopus 로고    scopus 로고
    • Isobolographic characterization of interactions between vigabatrin and tiagabine in two experimental models of epilepsy. Prog. Neuropsychopharmacol
    • Luszczki, J.J.; Czuczwar, S.J. Isobolographic characterization of interactions between vigabatrin and tiagabine in two experimental models of epilepsy. Prog. Neuropsychopharmacol. Biol. Psychiatry 2007, 31, 529-538.
    • (2007) Biol. Psychiatry , vol.31 , pp. 529-538
    • Luszczki, J.J.1    Czuczwar, S.J.2
  • 46
    • 0038107702 scopus 로고    scopus 로고
    • Interactions of tiagabine with some antiepileptics in the maximal electroshock in mice
    • Luszczki, J.; Swiader, M.; Czuczwar, M.; Kis, J.; Czuczwar, S.J. Interactions of tiagabine with some antiepileptics in the maximal electroshock in mice. Pharmacol. Biochem. Behav. 2003, 75, 319-327.
    • (2003) Pharmacol. Biochem. Behav , vol.75 , pp. 319-327
    • Luszczki, J.1    Swiader, M.2    Czuczwar, M.3    Kis, J.4    Czuczwar, S.J.5
  • 47
    • 5344234859 scopus 로고    scopus 로고
    • Isobolographic and subthreshold analysis of interactions among felbamate and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice
    • Borowicz, K.K.; Luszczki, J.J.; Czuczwar, S.J. Isobolographic and subthreshold analysis of interactions among felbamate and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice. Epilepsia 2004, 45, 1176-1183.
    • (2004) Epilepsia , vol.45 , pp. 1176-1183
    • Borowicz, K.K.1    Luszczki, J.J.2    Czuczwar, S.J.3
  • 48
    • 0035207331 scopus 로고    scopus 로고
    • Monotherapy versus polytherapy for epilepsy: A multicenter double-blind randomized study
    • Deckers, C.L.; Hekster, Y.A.; Keyser, A.; van Lier, H.J.; Meinardi, H.; Renier, W.O. Monotherapy versus polytherapy for epilepsy: a multicenter double-blind randomized study. Epilepsia 2001, 42, 1387-1394.
    • (2001) Epilepsia , vol.42 , pp. 1387-1394
    • Deckers, C.L.1    Hekster, Y.A.2    Keyser, A.3    van Lier, H.J.4    Meinardi, H.5    Renier, W.O.6
  • 49
    • 15844391803 scopus 로고    scopus 로고
    • Complaints associated with the use of antiepileptic drugs: Results from a community-based study
    • Carpay, J.A.; Aldenkamp, A.P.; van Donselaar, C.A. Complaints associated with the use of antiepileptic drugs: results from a community-based study. Seizure 2005, 14, 198-206.
    • (2005) Seizure , vol.14 , pp. 198-206
    • Carpay, J.A.1    Aldenkamp, A.P.2    van Donselaar, C.A.3
  • 50
    • 9144222215 scopus 로고    scopus 로고
    • Adjunctive therapy versus alternative monotherapy in patients with partial epilepsy failing on a single drug: A multicentre, randomised, pragmatic controlled trial
    • Beghi, E.; Gatti, G.; Tonini, C.; Ben-Menachem, E.; Chadwick, D.W.; Nikanorova, M.; Gromov, S.A.; Smith, P.E.; Specchio, L.M.; Perucca, E. Adjunctive therapy versus alternative monotherapy in patients with partial epilepsy failing on a single drug: a multicentre, randomised, pragmatic controlled trial. Epilepsy Res. 2003, 57, 1-13.
    • (2003) Epilepsy Res , vol.57 , pp. 1-13
    • Beghi, E.1    Gatti, G.2    Tonini, C.3    Ben-Menachem, E.4    Chadwick, D.W.5    Nikanorova, M.6    Gromov, S.A.7    Smith, P.E.8    Specchio, L.M.9    Perucca, E.10
  • 51
    • 0033760422 scopus 로고    scopus 로고
    • Epilepsy after the first drug fails: Substitution or add-on?
    • Kwan, P.; Brodie, M.J. Epilepsy after the first drug fails: substitution or add-on? Seizure 2000, 9, 464-468.
    • (2000) Seizure , vol.9 , pp. 464-468
    • Kwan, P.1    Brodie, M.J.2
  • 52
    • 0036747357 scopus 로고    scopus 로고
    • Seizure freedom with more than one antiepileptic drug
    • Stephen, L.J.; Brodie, M.J. Seizure freedom with more than one antiepileptic drug. Seizure 2002, 11, 349-351.
    • (2002) Seizure , vol.11 , pp. 349-351
    • Stephen, L.J.1    Brodie, M.J.2
  • 53
    • 0031883784 scopus 로고    scopus 로고
    • Carbamazepine toxicity with lamotrigine: Pharmacokinetic or pharmacodynamic interaction?
    • Besag, F.M.; Berry, D.J.; Pool, F.; Newbery, J.E.; Subel, B. Carbamazepine toxicity with lamotrigine: pharmacokinetic or pharmacodynamic interaction? Epilepsia 1998, 39, 183-187.
    • (1998) Epilepsia , vol.39 , pp. 183-187
    • Besag, F.M.1    Berry, D.J.2    Pool, F.3    Newbery, J.E.4    Subel, B.5
  • 54
    • 0030817654 scopus 로고    scopus 로고
    • Effect of lamotrigine on carbamazepine epoxide/carbamazepine serum concentration ratios in adult patients with epilepsy
    • Gidal, B.E.; Rutecki, P.; Shaw, R.; Maly, M.M.; Collins, D.M.; Pitterle, M.E. Effect of lamotrigine on carbamazepine epoxide/carbamazepine serum concentration ratios in adult patients with epilepsy. Epilepsy Res. 1997, 28, 207-211.
    • (1997) Epilepsy Res , vol.28 , pp. 207-211
    • Gidal, B.E.1    Rutecki, P.2    Shaw, R.3    Maly, M.M.4    Collins, D.M.5    Pitterle, M.E.6
  • 55
    • 0031413729 scopus 로고    scopus 로고
    • No increase in carbamazepine-10,11-epoxide during addition of lamotrigine treatment in children
    • Eriksson, A.S.; Boreus, L.O. No increase in carbamazepine-10,11-epoxide during addition of lamotrigine treatment in children. Ther. Drug Monit. 1997, 19, 499-501.
    • (1997) Ther. Drug Monit , vol.19 , pp. 499-501
    • Eriksson, A.S.1    Boreus, L.O.2
  • 56
    • 0026597799 scopus 로고
    • Lamotrigine-induced carbamazepine toxicity: An interaction with carbamazepine-10,11-epoxide
    • Warner, T.; Patsalos, P.N.; Prevett, M.; Elyas, A.A.; Duncan, J.S. Lamotrigine-induced carbamazepine toxicity: an interaction with carbamazepine-10,11-epoxide. Epilepsy Res. 1992, 11, 147-150.
    • (1992) Epilepsy Res , vol.11 , pp. 147-150
    • Warner, T.1    Patsalos, P.N.2    Prevett, M.3    Elyas, A.A.4    Duncan, J.S.5
  • 57
    • 34247268472 scopus 로고    scopus 로고
    • Clinical use of antiepileptic drugs at a referral centre for epilepsy
    • Landmark, C.J.; Rytter, E.; Johannessen, S.I. Clinical use of antiepileptic drugs at a referral centre for epilepsy. Seizure 2007, 16, 356-364.
    • (2007) Seizure , vol.16 , pp. 356-364
    • Landmark, C.J.1    Rytter, E.2    Johannessen, S.I.3
  • 58
    • 77955581015 scopus 로고    scopus 로고
    • Identification of potentially effective antiepileptic drug combinations in patients with epilepsy
    • Welty, T.; Elgavish, R.; Faught, E.; Barnes, B. Identification of potentially effective antiepileptic drug combinations in patients with epilepsy. Epilepsia 2009, 50, 94.
    • (2009) Epilepsia , vol.50 , pp. 94
    • Welty, T.1    Elgavish, R.2    Faught, E.3    Barnes, B.4
  • 59
    • 0030975686 scopus 로고    scopus 로고
    • Lamotrigine substitution study: Evidence for synergism with sodium valproate? 105 Study Group
    • Brodie, M.J.; Yuen, A.W. Lamotrigine substitution study: evidence for synergism with sodium valproate? 105 Study Group. Epilepsy Res. 1997, 26, 423-432.
    • (1997) Epilepsy Res , vol.26 , pp. 423-432
    • Brodie, M.J.1    Yuen, A.W.2
  • 60
    • 0032799794 scopus 로고    scopus 로고
    • The efficacy of valproate-lamotrigine comedication in refractory complex partial seizures: Evidence for a pharmacodynamic interaction
    • Pisani, F.; Oteri, G.; Russo, M.F.; Di Perri, R.; Perucca, E.; Richens, A. The efficacy of valproate-lamotrigine comedication in refractory complex partial seizures: evidence for a pharmacodynamic interaction. Epilepsia 1999, 40, 1141-1146.
    • (1999) Epilepsia , vol.40 , pp. 1141-1146
    • Pisani, F.1    Oteri, G.2    Russo, M.F.3    di Perri, R.4    Perucca, E.5    Richens, A.6
  • 61
    • 0033646627 scopus 로고    scopus 로고
    • Clinical study of lamotrigine and valproic acid in patients with epilepsy: Using a drug interaction to advantage? Ther
    • Morris, R.G.; Black, A.B.; Lam, E.; Westley, I.S. Clinical study of lamotrigine and valproic acid in patients with epilepsy: using a drug interaction to advantage? Ther. Drug Monit. 2000, 22, 656-660.
    • (2000) Drug Monit , vol.22 , pp. 656-660
    • Morris, R.G.1    Black, A.B.2    Lam, E.3    Westley, I.S.4
  • 63
    • 0028284314 scopus 로고
    • Therapeutic interaction of lamotrigine and sodium valproate in intractable myoclonic epilepsy
    • Ferrie, C.D.; Panayiotopoulos, C.P. Therapeutic interaction of lamotrigine and sodium valproate in intractable myoclonic epilepsy. Seizure 1994, 3, 157-159.
    • (1994) Seizure , vol.3 , pp. 157-159
    • Ferrie, C.D.1    Panayiotopoulos, C.P.2
  • 65
    • 0022907940 scopus 로고
    • Antiepileptic drug combinations and experimental background: The case of phenobarbital and phenytoin
    • Bourgeois, B.F. Antiepileptic drug combinations and experimental background: the case of phenobarbital and phenytoin. Naunyn Schmiedebergs Arch. Pharmacol. 1986, 333, 406-411.
    • (1986) Naunyn Schmiedebergs Arch. Pharmacol , vol.333 , pp. 406-411
    • Bourgeois, B.F.1
  • 66
    • 0027221666 scopus 로고
    • Combination valproate-carbamazepine therapy in partial epilepsies resistant to carbamazepine monotherapy
    • Harden, C.L.; Zisfein, J.; Atos-Radzion, C.E.; Tuchman, A.J. Combination valproate-carbamazepine therapy in partial epilepsies resistant to carbamazepine monotherapy. J. Epilepsy 1993, 6, 91-94.
    • (1993) J. Epilepsy , vol.6 , pp. 91-94
    • Harden, C.L.1    Zisfein, J.2    Atos-Radzion, C.E.3    Tuchman, A.J.4
  • 68
    • 0032495660 scopus 로고    scopus 로고
    • Lamotrigine and topiramate may be a useful combination
    • Stephens, L.J.; Sills, G.J.; Brodie, M.J. Lamotrigine and topiramate may be a useful combination. Lancet 1998, 351, 958-959.
    • (1998) Lancet , vol.351 , pp. 958-959
    • Stephens, L.J.1    Sills, G.J.2    Brodie, M.J.3
  • 69
    • 77951561572 scopus 로고    scopus 로고
    • Relationship between adverse effects of antiepileptic drugs, number of coprescribed drugs, and drug load in a large cohort of consecutive patients with drug-refractory epilepsy
    • Canevini, M.P.; De Sarro, G.; Galimberti, C.A.; Gatti, G.; Licchetta, L.; Malerba, A.; Muscas, G.; La Neve, A.; Striano, P.; Perucca, E. Relationship between adverse effects of antiepileptic drugs, number of coprescribed drugs, and drug load in a large cohort of consecutive patients with drug-refractory epilepsy. Epilepsia 2010, 51, 797-804.
    • (2010) Epilepsia , vol.51 , pp. 797-804
    • Canevini, M.P.1    de Sarro, G.2    Galimberti, C.A.3    Gatti, G.4    Licchetta, L.5    Malerba, A.6    Muscas, G.7    la Neve, A.8    Striano, P.9    Perucca, E.10
  • 70
    • 68549135272 scopus 로고    scopus 로고
    • Managing severe epilepsy syndromes of early childhood
    • quiz 33S-26S
    • Wheless, J.W. Managing severe epilepsy syndromes of early childhood. J. Child Neurol. 2009, 24, 24S-32S; quiz 33S-26S.
    • (2009) J. Child Neurol , vol.24
    • Wheless, J.W.1
  • 71
    • 0038144915 scopus 로고    scopus 로고
    • Laboratory Monitoring of Antiepileptic Drugs
    • 5th ed.; Levy, R.H., Mattson, R.H., Meldrum, B.S., Perucca, E., Eds. Lippincott, Williams & Wilkins: Philadelphia, PA, USA
    • Johannessen, S.I.; Tomson, T. Laboratory Monitoring of Antiepileptic Drugs. In Antiepileptic Drugs, 5th ed.; Levy, R.H., Mattson, R.H., Meldrum, B.S., Perucca, E., Eds. Lippincott, Williams & Wilkins: Philadelphia, PA, USA, 2002; pp. 104-111.
    • (2002) Antiepileptic Drugs , pp. 104-111
    • Johannessen, S.I.1    Tomson, T.2
  • 72
    • 27644448562 scopus 로고    scopus 로고
    • Overtreatment in epilepsy: How it occurs and how it can be avoided
    • Perucca, E.; Kwan, P. Overtreatment in epilepsy: how it occurs and how it can be avoided. CNS Drugs 2005, 19, 897-908.
    • (2005) CNS Drugs , vol.19 , pp. 897-908
    • Perucca, E.1    Kwan, P.2
  • 73
    • 65549132073 scopus 로고    scopus 로고
    • Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): II. Teratogenesis and perinatal outcomes: Report of the Quality Standards Subcommittee and Therapeutics and Technology Subcommittee of the American Academy of Neurology and the American Epilepsy Society
    • Harden, C.L.; Meador, K.J.; Pennell, P.B.; Hauser, W.A.; Gronseth, G.S.; French, J.A.; Wiebe, S.; Thurman, D.; Koppel, B.S.; Kaplan, P.W.; et al. Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): II. Teratogenesis and perinatal outcomes: Report of the Quality Standards Subcommittee and Therapeutics and Technology Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Epilepsia 2009, 50, 1237-1246.
    • (2009) Epilepsia , vol.50 , pp. 1237-1246
    • Harden, C.L.1    Meador, K.J.2    Pennell, P.B.3    Hauser, W.A.4    Gronseth, G.S.5    French, J.A.6    Wiebe, S.7    Thurman, D.8    Koppel, B.S.9    Kaplan, P.W.10
  • 74
    • 20444382337 scopus 로고    scopus 로고
    • Antiepileptic drug use of women with epilepsy and congenital malformations in offspring
    • Artama, M.; Auvinen, A.; Raudaskoski, T.; Isojarvi, I.; Isojarvi, J. Antiepileptic drug use of women with epilepsy and congenital malformations in offspring. Neurology 2005, 64, 1874-1878.
    • (2005) Neurology , vol.64 , pp. 1874-1878
    • Artama, M.1    Auvinen, A.2    Raudaskoski, T.3    Isojarvi, I.4    Isojarvi, J.5
  • 76
    • 33846850154 scopus 로고    scopus 로고
    • Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy
    • Brodie, M. J.; Perucca, E.; Ryvlin, P.; Ben-Menachem, E.; Meencke, H.J. Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy. Neurology 2007, 68, 402-408.
    • (2007) Neurology , vol.68 , pp. 402-408
    • Brodie, M.J.1    Perucca, E.2    Ryvlin, P.3    Ben-Menachem, E.4    Meencke, H.J.5
  • 78
    • 70349814070 scopus 로고    scopus 로고
    • Levetiracetam extended release and levetiracetam immediate release as adjunctive treatment for partial-onset seizures: An indirect comparison of treatment-emergent adverse events using meta-analytic techniques
    • Richy, F.F.; Banerjee, S.; Brabant, Y.; Helmers, S. Levetiracetam extended release and levetiracetam immediate release as adjunctive treatment for partial-onset seizures: an indirect comparison of treatment-emergent adverse events using meta-analytic techniques. Epilepsy Behav. 2009, 16, 240-245.
    • (2009) Epilepsy Behav , vol.16 , pp. 240-245
    • Richy, F.F.1    Banerjee, S.2    Brabant, Y.3    Helmers, S.4
  • 79
    • 2542523065 scopus 로고    scopus 로고
    • Improved CNS tolerability following conversion from immediate to extended-release carbamazepine
    • Miller, A.D.; Krauss, G.L.; Hamzeh, F.M. Improved CNS tolerability following conversion from immediate to extended-release carbamazepine. Acta. Neurol. Scand. 2004, 109, 374-377.
    • (2004) Acta. Neurol. Scand , vol.109 , pp. 374-377
    • Miller, A.D.1    Krauss, G.L.2    Hamzeh, F.M.3
  • 80
    • 37849053121 scopus 로고    scopus 로고
    • Quantifying the response to antiepileptic drugs: Effect of past treatment history
    • Schiller, Y.; Najjar, Y. Quantifying the response to antiepileptic drugs: effect of past treatment history. Neurology 2008, 70, 54-65.
    • (2008) Neurology , vol.70 , pp. 54-65
    • Schiller, Y.1    Najjar, Y.2
  • 81
    • 79960361003 scopus 로고    scopus 로고
    • Acute Administration of Benzodiazepines as Part of Treatment Strategies for Epilepsy
    • doi:10.1111/j.1755-5949.2010.00139.x
    • Wolf, P. Acute Administration of Benzodiazepines as Part of Treatment Strategies for Epilepsy. CNS Neurosci. Ther. 2010, doi:10.1111/j.1755-5949.2010.00139.x.
    • (2010) CNS Neurosci. Ther
    • Wolf, P.1
  • 82
    • 33645015647 scopus 로고    scopus 로고
    • Effects of intermittent levetiracetam dosing in a patient with refractory daily seizures
    • Friedman, D.; French, J.A. Effects of intermittent levetiracetam dosing in a patient with refractory daily seizures. Neurology 2006, 66, 590-591.
    • (2006) Neurology , vol.66 , pp. 590-591
    • Friedman, D.1    French, J.A.2


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