The suppressor of cytokine signalling 2 (SOCS2) is a key repressor of insulin secretion

Diabetologia

Volumn 53, Issue 9, 2010, Pages 1935-1946

  Lebrun, P ^a,b   Cognard, E ^a,b   Gontard, P ^a,b   Bellon Paul, R ^a,b   Filloux, C ^a,b   Berthault, M F ^c   Magnan, C ^c   Ruberte, J ^d,e,f   Luppo, M ^d,e   Pujol, A ^d,e   Pachera, N ^f   Herchuelz, A ^f   Bosch, F ^d,e   Van Obberghen, E ^a,b,g  

^a INSERM   (France)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

^c CNRS   (France)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^e INSTITUTO DE SALUD CARLOS III   (Spain)

^f UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^g PASTEUR HOSPITAL   (France)

Author keywords

Glucose intolerance; Insulin secretion; Pancreatic beta cell; Proinsulin maturation; SOCS; Transgenic mice

Indexed keywords

CALCIUM; GLUCOSE; INSULIN; SUPPRESSOR OF CYTOKINE SIGNALING 2; SOCS2 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL FUNCTION; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; HYPERGLYCEMIA; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSGENIC MOUSE; ANIMAL; BODY WEIGHT; C57BL MOUSE; GENETICS; METABOLISM; MOUSE; PANCREAS ISLET; PHENOTYPE; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION (PROCESS); WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BODY WEIGHT; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPLASMIC RETICULUM; INSULIN; ISLETS OF LANGERHANS; MICE; MICE, INBRED C57BL; PHENOTYPE; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 77955550256     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1786-9     Document Type: Article

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