메뉴 건너뛰기




Volumn 25, Issue 3, 2010, Pages 176-185

PPAR modulation of kinase-linked receptor signaling in physiology and disease

Author keywords

[No Author keywords available]

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHOSPHOTRANSFERASE;

EID: 77955536994     PISSN: 15489213     EISSN: 15489221     Source Type: Journal    
DOI: 10.1152/physiol.00018.2010     Document Type: Review
Times cited : (19)

References (70)
  • 1
    • 0142124288 scopus 로고    scopus 로고
    • Induction of plasminogen activator inhibitor i by the PPARalpha ligand, Wy-14,643, is dependent on ERK1/2 signalling pathway
    • Banfi C, Auwerx J, Poma F, Tremoli E, Mussoni L. Induction of plasminogen activator inhibitor I by the PPARalpha ligand, Wy-14,643, is dependent on ERK1/2 signalling pathway. Thromb Haemost 90: 611-619, 2003.
    • (2003) Thromb Haemost , vol.90 , pp. 611-619
    • Banfi, C.1    Auwerx, J.2    Poma, F.3    Tremoli, E.4    Mussoni, L.5
  • 2
    • 34548289084 scopus 로고    scopus 로고
    • MAPK kinases as nucleo-cytoplasmic shuttles for PPARgamma
    • Burgermeister E, Seger R. MAPK kinases as nucleo-cytoplasmic shuttles for PPARgamma. Cell Cycle 6: 1539-1548, 2007.
    • (2007) Cell Cycle , vol.6 , pp. 1539-1548
    • Burgermeister, E.1    Seger, R.2
  • 3
    • 34547589477 scopus 로고    scopus 로고
    • Modulation of PPAR activity via phosphorylation
    • Burns KA, Vanden Heuvel JP. Modulation of PPAR activity via phosphorylation. Biochim Biophys Acta 1771: 952-960, 2007.
    • (2007) Biochim Biophys Acta , vol.1771 , pp. 952-960
    • Burns, K.A.1    Vanden Heuvel, J.P.2
  • 4
    • 67349270856 scopus 로고    scopus 로고
    • Trafficking of receptor tyrosine kinases to the nucleus
    • Carpenter G, Liao HJ. Trafficking of receptor tyrosine kinases to the nucleus. Exp Cell Res 315: 1556-1566, 2009.
    • (2009) Exp Cell Res , vol.315 , pp. 1556-1566
    • Carpenter, G.1    Liao, H.J.2
  • 5
    • 38649129072 scopus 로고    scopus 로고
    • Troglitazone suppresses transforming growth factor betamediated fibrogenesis in retinal pigment epithelial cells
    • Cheng HC, Ho TC, Chen SL, Lai HY, Hong KF, Tsao YP. Troglitazone suppresses transforming growth factor betamediated fibrogenesis in retinal pigment epithelial cells. Mol Vision 14: 95-104, 2008.
    • (2008) Mol Vision , vol.14 , pp. 95-104
    • Cheng, H.C.1    Ho, T.C.2    Chen, S.L.3    Lai, H.Y.4    Hong, K.F.5    Tsao, Y.P.6
  • 6
    • 59149084957 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonists as insulin sensitizers: From the discovery to recent progress
    • Cho N, Momose Y. Peroxisome proliferator-activated receptor gamma agonists as insulin sensitizers: from the discovery to recent progress. Curr Topics Med Chem 8: 1483-1507, 2008.
    • (2008) Curr Topics Med Chem , vol.8 , pp. 1483-1507
    • Cho, N.1    Momose, Y.2
  • 8
    • 69949107891 scopus 로고    scopus 로고
    • Circulating fibroblast growth factor 21 is induced by peroxisome proliferator-activated receptor agonists but not ketosis in man
    • Christodoulides C, Dyson P, Sprecher D, Tsintzas K, Karpe F. Circulating fibroblast growth factor 21 is induced by peroxisome proliferator-activated receptor agonists but not ketosis in man. J Clin Endocrinol Metab 94: 3594-3601, 2009.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3594-3601
    • Christodoulides, C.1    Dyson, P.2    Sprecher, D.3    Tsintzas, K.4    Karpe, F.5
  • 9
    • 33845979155 scopus 로고    scopus 로고
    • The insulin-like growth factor-binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors
    • Degenhardt T, Matilainen M, Herzig KH, Dunlop TW, Carlberg C. The insulin-like growth factor-binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors. J Biol Chem 281: 39607-39619, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 39607-39619
    • Degenhardt, T.1    Matilainen, M.2    Herzig, K.H.3    Dunlop, T.W.4    Carlberg, C.5
  • 10
    • 2542454565 scopus 로고    scopus 로고
    • Be fit or be sick: Peroxisome proliferator-activated receptors are down the road
    • Desvergne B, Michalik L, Wahli W. Be fit or be sick: peroxisome proliferator-activated receptors are down the road. Mol Endocrinol 18: 1321-1332, 2004.
    • (2004) Mol Endocrinol , vol.18 , pp. 1321-1332
    • Desvergne, B.1    Michalik, L.2    Wahli, W.3
  • 11
    • 0036771764 scopus 로고    scopus 로고
    • Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signalling pathway
    • Di-Poi N, Tan NS, Michalik L, Wahli W, Desvergne B. Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signalling pathway. Mol Cell 10: 721-733, 2002.
    • (2002) Mol Cell , vol.10 , pp. 721-733
    • Di-Poi, N.1    Tan, N.S.2    Michalik, L.3    Wahli, W.4    Desvergne, B.5
  • 12
    • 34347369726 scopus 로고    scopus 로고
    • Hypoglycemic action of thiazolidinediones/peroxisome proliferator- activated receptor gamma by inhibition of the c-Jun NH2-terminal kinase pathway
    • Diaz-Delfin J, Morales M, Caelles C. Hypoglycemic action of thiazolidinediones/peroxisome proliferator-activated receptor gamma by inhibition of the c-Jun NH2-terminal kinase pathway. Diabetes 56: 1865-1871, 2007.
    • (2007) Diabetes , vol.56 , pp. 1865-1871
    • Diaz-Delfin, J.1    Morales, M.2    Caelles, C.3
  • 13
    • 0026517010 scopus 로고
    • Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors
    • Dreyer C, Krey G, Keller H, Givel F, Helftenbein G, Wahli W. Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors. Cell 68: 879-887, 1992.
    • (1992) Cell , vol.68 , pp. 879-887
    • Dreyer, C.1    Krey, G.2    Keller, H.3    Givel, F.4    Helftenbein, G.5    Wahli, W.6
  • 14
    • 0037189578 scopus 로고    scopus 로고
    • Differential regulation of vascular endothelial growth factor expression by peroxisome proliferator-activated receptors in bladder cancer cells
    • Fauconnet S, Lascombe I, Chabannes E, Adessi GL, Desvergne B, Wahli W, Bittard H. Differential regulation of vascular endothelial growth factor expression by peroxisome proliferator-activated receptors in bladder cancer cells. J Biol Chem 277: 23534-23543, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 23534-23543
    • Fauconnet, S.1    Lascombe, I.2    Chabannes, E.3    Adessi, G.L.4    Desvergne, B.5    Wahli, W.6    Bittard, H.7
  • 15
    • 32644460092 scopus 로고    scopus 로고
    • From molecular action to physiological outputs: Peroxisome proliferator- activated receptors are nuclear receptors at the crossroads of key cellular functions
    • Feige JN, Gelman L, Michalik L, Desvergne B, Wahli W. From molecular action to physiological outputs: peroxisome proliferator- activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog Lipid Res 45: 120-159, 2006.
    • (2006) Prog Lipid Res , vol.45 , pp. 120-159
    • Feige, J.N.1    Gelman, L.2    Michalik, L.3    Desvergne, B.4    Wahli, W.5
  • 16
    • 0035824518 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3
    • Fu M, Zhang J, Zhu X, Myles DE, Willson TM, Liu X, Chen YE. Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3. J Biol Chem 276: 45888-45894, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 45888-45894
    • Fu, M.1    Zhang, J.2    Zhu, X.3    Myles, D.E.4    Willson, T.M.5    Liu, X.6    Chen, Y.E.7
  • 17
    • 0344443788 scopus 로고    scopus 로고
    • Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signalling on epidermal growth factor receptor transactivation
    • Gardner OS, Dewar BJ, Earp HS, Samet JM, Graves LM. Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signalling on epidermal growth factor receptor transactivation. J Biol Chem 278: 46261-46269, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 46261-46269
    • Gardner, O.S.1    Dewar, B.J.2    Earp, H.S.3    Samet, J.M.4    Graves, L.M.5
  • 18
    • 15044354314 scopus 로고    scopus 로고
    • Kinase signalling cascades that modulate peroxisome proliferatoractivated receptors
    • Gelman L, Michalik L, Desvergne B, Wahli W. Kinase signalling cascades that modulate peroxisome proliferatoractivated receptors. Curr Opin Cell Biol 17: 216-222, 2005.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 216-222
    • Gelman, L.1    Michalik, L.2    Desvergne, B.3    Wahli, W.4
  • 19
    • 1842733168 scopus 로고    scopus 로고
    • Disruption of transforming growth factor beta signalling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma
    • Ghosh AK, Bhattacharyya S, Lakos G, Chen SJ, Mori Y, Varga J. Disruption of transforming growth factor beta signalling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma. Arthritis Rheum 50: 1305-1318, 2004.
    • (2004) Arthritis Rheum , vol.50 , pp. 1305-1318
    • Ghosh, A.K.1    Bhattacharyya, S.2    Lakos, G.3    Chen, S.J.4    Mori, Y.5    Varga, J.6
  • 20
    • 70349331686 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator
    • Ghosh AK, Bhattacharyya S, Wei J, Kim S, Barak Y, Mori Y, Varga J. Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator. FASEB J 23: 2968-2977, 2009.
    • (2009) FASEB J , vol.23 , pp. 2968-2977
    • Ghosh, A.K.1    Bhattacharyya, S.2    Wei, J.3    Kim, S.4    Barak, Y.5    Mori, Y.6    Varga, J.7
  • 21
    • 48349108129 scopus 로고    scopus 로고
    • Constitutive Smad signalling and Smad-dependent collagen gene expression in mouse embryonic fibroblasts lacking peroxisome proliferatoractivated receptor-gamma
    • Ghosh AK, Wei J, Wu M, Varga J. Constitutive Smad signalling and Smad-dependent collagen gene expression in mouse embryonic fibroblasts lacking peroxisome proliferatoractivated receptor-gamma. Biochem Biophys Res Commun 374: 231-236, 2008.
    • (2008) Biochem Biophys Res Commun , vol.374 , pp. 231-236
    • Ghosh, A.K.1    Wei, J.2    Wu, M.3    Varga, J.4
  • 23
    • 53249092406 scopus 로고    scopus 로고
    • Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3- dependent pathways
    • Gressner OA, Lahme B, Rehbein K, Siluschek M, Weiskirchen R, Gressner AM. Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3- dependent pathways. J Hepatol 49: 758-767, 2008.
    • (2008) J Hepatol , vol.49 , pp. 758-767
    • Gressner, O.A.1    Lahme, B.2    Rehbein, K.3    Siluschek, M.4    Weiskirchen, R.5    Gressner, A.M.6
  • 24
    • 0346729955 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma ligands inhibit TGF-beta 1-induced fibronectin expression in glomerular mesangial cells
    • Guo B, Koya D, Isono M, Sugimoto T, Kashiwagi A, Haneda M. Peroxisome proliferator-activated receptor-gamma ligands inhibit TGF-beta 1-induced fibronectin expression in glomerular mesangial cells. Diabetes 53: 200-208, 2004.
    • (2004) Diabetes , vol.53 , pp. 200-208
    • Guo, B.1    Koya, D.2    Isono, M.3    Sugimoto, T.4    Kashiwagi, A.5    Haneda, M.6
  • 25
    • 7244253108 scopus 로고    scopus 로고
    • Transforming growth factor-beta (TGF-beta) activates cytosolic phospholipase A2alpha (cPLA2alpha)-mediated prostaglandin E2 (PGE)2/EP1 and peroxisome proliferator-activated receptorgamma (PPAR-gamma)/Smad signalling pathways in human liver cancer cells. A novel mechanism for subversion of TGFbeta- induced mitoinhibition
    • Han C, Demetris AJ, Liu Y, Shelhamer JH, Wu T. Transforming growth factor-beta (TGF-beta) activates cytosolic phospholipase A2alpha (cPLA2alpha)-mediated prostaglandin E2 (PGE)2/EP1 and peroxisome proliferator-activated receptorgamma (PPAR-gamma)/Smad signalling pathways in human liver cancer cells. A novel mechanism for subversion of TGFbeta- induced mitoinhibition. J Biol Chem 279: 44344-44354, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 44344-44354
    • Han, C.1    Demetris, A.J.2    Liu, Y.3    Shelhamer, J.H.4    Wu, T.5
  • 26
    • 58649105337 scopus 로고    scopus 로고
    • Fish oil inhibits human lung carcinoma cell growth by suppressing integrinlinked kinase
    • Han S, Sun X, Ritzenthaler JD, Roman J. Fish oil inhibits human lung carcinoma cell growth by suppressing integrinlinked kinase. Mol Cancer Res 7: 108-117, 2009.
    • (2009) Mol Cancer Res , vol.7 , pp. 108-117
    • Han, S.1    Sun, X.2    Ritzenthaler, J.D.3    Roman, J.4
  • 28
    • 57649178299 scopus 로고    scopus 로고
    • 15-Deoxy-delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53
    • Ho TC, Chen SL, Yang YC, Chen CY, Feng FP, Hsieh JW, Cheng HC, Tsao YP. 15-Deoxy-delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53. J Biol Chem 283: 30273-30288, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 30273-30288
    • Ho, T.C.1    Chen, S.L.2    Yang, Y.C.3    Chen, C.Y.4    Feng, F.P.5    Hsieh, J.W.6    Cheng, H.C.7    Tsao, Y.P.8
  • 29
    • 0036314868 scopus 로고    scopus 로고
    • Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxydelta(12,14)- prostaglandin J(2), ciglitazone, and GW1929
    • Huang WC, Chio CC, Chi KH, Wu HM, Lin WW. Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxydelta( 12,14)-prostaglandin J(2), ciglitazone, and GW1929. Exp Cell Res 277: 192-200, 2002.
    • (2002) Exp Cell Res , vol.277 , pp. 192-200
    • Huang, W.C.1    Chio, C.C.2    Chi, K.H.3    Wu, H.M.4    Lin, W.W.5
  • 31
    • 10744227563 scopus 로고    scopus 로고
    • Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisome proliferator-activated receptor-alpha partly via blockade of c-Jun NH2-terminal kinase pathway
    • Irukayama-Tomobe Y, Miyauchi T, Sakai S, Kasuya Y, Ogata T, Takanashi M, Iemitsu M, Sudo T, Goto K, Yamaguchi I. Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisome proliferator-activated receptor-alpha partly via blockade of c-Jun NH2-terminal kinase pathway. Circulation 109: 904-910, 2004.
    • (2004) Circulation , vol.109 , pp. 904-910
    • Irukayama-Tomobe, Y.1    Miyauchi, T.2    Sakai, S.3    Kasuya, Y.4    Ogata, T.5    Takanashi, M.6    Iemitsu, M.7    Sudo, T.8    Goto, K.9    Yamaguchi, I.10
  • 32
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann I, Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 347: 645-650, 1990.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 33
    • 0032699670 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting
    • Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli W. Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J Clin Invest 103: 1489-1498, 1999.
    • (1999) J Clin Invest , vol.103 , pp. 1489-1498
    • Kersten, S.1    Seydoux, J.2    Peters, J.M.3    Gonzalez, F.J.4    Desvergne, B.5    Wahli, W.6
  • 34
    • 15744366162 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by down-regulation of kinase activity
    • Kim DJ, Murray IA, Burns AM, Gonzalez FJ, Perdew GH, Peters JM. Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by down-regulation of kinase activity. J Biol Chem 280: 9519-9527, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 9519-9527
    • Kim, D.J.1    Murray, I.A.2    Burns, A.M.3    Gonzalez, F.J.4    Perdew, G.H.5    Peters, J.M.6
  • 36
    • 67949095966 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor delta regulates extracellular matrix and apoptosis of vascular smooth muscle cells through the activation of transforming growth factor-beta1/Smad3
    • Kim HJ, Kim MY, Jin H, Kim HJ, Kang SS, Kim HJ, Lee JH, Chang KC, Hwang JY, Yabe-Nishimura C, Kim JH, Seo HG. Peroxisome proliferator-activated receptor delta regulates extracellular matrix and apoptosis of vascular smooth muscle cells through the activation of transforming growth factor-beta1/Smad3. Circ Res 105: 16-24, 2009.
    • (2009) Circ Res , vol.105 , pp. 16-24
    • Kim, H.J.1    Kim, M.Y.2    Jin, H.3    Kim, H.J.4    Kang, S.S.5    Kim, H.J.6    Lee, J.H.7    Chang, K.C.8    Hwang, J.Y.9    Yabe-Nishimura, C.10    Kim, J.H.11    Seo, H.G.12
  • 37
    • 34250843186 scopus 로고    scopus 로고
    • Pro-MMP-2 activation by the PPARgamma agonist, ciglitazone, induces cell invasion through the generation of ROS and the activation of ERK
    • Kim KH, Cho YS, Park JM, Yoon SO, Kim KW, Chung AS. Pro-MMP-2 activation by the PPARgamma agonist, ciglitazone, induces cell invasion through the generation of ROS and the activation of ERK. FEBS Lett 581: 3303-3310, 2007.
    • (2007) FEBS Lett , vol.581 , pp. 3303-3310
    • Kim, K.H.1    Cho, Y.S.2    Park, J.M.3    Yoon, S.O.4    Kim, K.W.5    Chung, A.S.6
  • 39
    • 34547112065 scopus 로고    scopus 로고
    • Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle
    • Kramer DK, Al-Khalili L, Guigas B, Leng Y, Garcia- Roves PM, Krook A. Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle. J Biol Chem 282: 19313-19320, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 19313-19320
    • Kramer, D.K.1    Al-Khalili, L.2    Guigas, B.3    Leng, Y.4    Garcia- Roves, P.M.5    Krook, A.6
  • 40
    • 58849101326 scopus 로고    scopus 로고
    • The 15-deoxy-delta 12,14-prostaglandin J2 suppresses monocyte chemoattractant protein-1 expression in IFN-gamma-stimulated astrocytes through induction of MAPK phosphatase-1
    • Lee JH, Woo JH, Woo SU, Kim KS, Park SM, Joe EH, Jou I. The 15-deoxy-delta 12,14-prostaglandin J2 suppresses monocyte chemoattractant protein-1 expression in IFN-gamma-stimulated astrocytes through induction of MAPK phosphatase-1. J Immunol 181: 8642-8649, 2008.
    • (2008) J Immunol , vol.181 , pp. 8642-8649
    • Lee, J.H.1    Woo, J.H.2    Woo, S.U.3    Kim, K.S.4    Park, S.M.5    Joe, E.H.6    Jou, I.7
  • 42
    • 33749249931 scopus 로고    scopus 로고
    • Apoptosis induced by troglitazone is both peroxisome proliferator- activated receptor-gamma- and ERKdependent in human non-small lung cancer cells
    • Li M, Lee TW, Yim AP, Mok TS, Chen GG. Apoptosis induced by troglitazone is both peroxisome proliferator-activated receptor-gamma- and ERKdependent in human non-small lung cancer cells. J Cell Physiol 209: 428-438, 2006.
    • (2006) J Cell Physiol , vol.209 , pp. 428-438
    • Li, M.1    Lee, T.W.2    Yim, A.P.3    Mok, T.S.4    Chen, G.G.5
  • 43
    • 33645454825 scopus 로고    scopus 로고
    • Hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists
    • Li Y, Wen X, Spataro BC, Hu K, Dai C, Liu Y. Hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists. J Am Soc Nephrol 17: 54-65, 2006.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 54-65
    • Li, Y.1    Wen, X.2    Spataro, B.C.3    Hu, K.4    Dai, C.5    Liu, Y.6
  • 44
    • 42549114387 scopus 로고    scopus 로고
    • Activation of peroxisome proliferatoractivated receptor-gamma by curcumin blocks the signalling pathways for PDGF and EGF in hepatic stellate cells
    • Lin J, Chen A. Activation of peroxisome proliferatoractivated receptor-gamma by curcumin blocks the signalling pathways for PDGF and EGF in hepatic stellate cells. Lab Invest 88: 529-540, 2008.
    • (2008) Lab Invest , vol.88 , pp. 529-540
    • Lin, J.1    Chen, A.2
  • 47
    • 0034644472 scopus 로고    scopus 로고
    • TGFbeta signalling in growth control, cancer, and heritable disorders
    • Massague J, Blain SW, Lo RS. TGFbeta signalling in growth control, cancer, and heritable disorders. Cell 103: 295-309, 2000.
    • (2000) Cell , vol.103 , pp. 295-309
    • Massague, J.1    Blain, S.W.2    Lo, R.S.3
  • 49
    • 0347753697 scopus 로고    scopus 로고
    • Peroxisomeproliferator- activated receptors and cancers: Complex stories
    • Michalik L, Desvergne B, Wahli W. Peroxisomeproliferator- activated receptors and cancers: complex stories. Nature Rev 4: 61-70, 2004.
    • (2004) Nature Rev , vol.4 , pp. 61-70
    • Michalik, L.1    Desvergne, B.2    Wahli, W.3
  • 50
    • 58149466606 scopus 로고    scopus 로고
    • PPARs mediate lipid signalling in inflammation and cancer
    • Michalik L, Wahli W. PPARs mediate lipid signalling in inflammation and cancer. PPAR Res 2008: 134059, 2008.
    • (2008) PPAR Res 2008 , pp. 134059
    • Michalik, L.1    Wahli, W.2
  • 52
    • 34247632325 scopus 로고    scopus 로고
    • Agonists of peroxisome proliferators-activated receptors (PPAR) alpha, beta/delta or gamma reduce transforming growth factor (TGF)-beta-induced proteoglycans' production in chondrocytes
    • Poleni PE, Bianchi A, Etienne S, Koufany M, Sebillaud S, Netter P, Terlain B, Jouzeau JY. Agonists of peroxisome proliferators-activated receptors (PPAR) alpha, beta/delta or gamma reduce transforming growth factor (TGF)-beta-induced proteoglycans' production in chondrocytes. Osteoarthritis Cartilage 15: 493-505, 2007.
    • (2007) Osteoarthritis Cartilage , vol.15 , pp. 493-505
    • Poleni, P.E.1    Bianchi, A.2    Etienne, S.3    Koufany, M.4    Sebillaud, S.5    Netter, P.6    Terlain, B.7    Jouzeau, J.Y.8
  • 53
    • 34249677947 scopus 로고    scopus 로고
    • FGF21: A missing link in the biology of fasting
    • Reitman ML. FGF21: a missing link in the biology of fasting. Cell Metab 5: 405-407, 2007.
    • (2007) Cell Metab , vol.5 , pp. 405-407
    • Reitman, M.L.1
  • 54
    • 50949105881 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor beta/ delta inhibits lipopolysaccharide-induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signalrelated kinase 1/2
    • Rodriguez-Calvo R, Serrano L, Coll T, Moullan N, Sanchez RM, Merlos M, Palomer X, Laguna JC, Michalik L, Wahli W, Vazquez-Carrera M. Activation of peroxisome proliferator-activated receptor beta/ delta inhibits lipopolysaccharide-induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signalrelated kinase 1/2. Diabetes 57: 2149-2157, 2008.
    • (2008) Diabetes , vol.57 , pp. 2149-2157
    • Rodriguez-Calvo, R.1    Serrano, L.2    Coll, T.3    Moullan, N.4    Sanchez, R.M.5    Merlos, M.6    Palomer, X.7    Laguna, J.C.8    Michalik, L.9    Wahli, W.10    Vazquez-Carrera, M.11
  • 56
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis: An inflammatory disease
    • Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med 340: 115-126, 1999.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 57
    • 69049113889 scopus 로고    scopus 로고
    • Fatty acid synthesis and PPARalpha hand in hand
    • Rotman N, Wahli W. Fatty acid synthesis and PPARalpha hand in hand. Chem Biol 16: 801-802, 2009.
    • (2009) Chem Biol , vol.16 , pp. 801-802
    • Rotman, N.1    Wahli, W.2
  • 58
    • 34247194273 scopus 로고    scopus 로고
    • Pioglitazone induces apoptosis in human vascular smooth muscle cells from diabetic patients involving the transforming growth factor-beta/ activin receptor-like kinase-4/5/7/Smad2 signalling pathway
    • Ruiz E, Redondo S, Gordillo-Moscoso A, Tejerina T. Pioglitazone induces apoptosis in human vascular smooth muscle cells from diabetic patients involving the transforming growth factor-beta/ activin receptor-like kinase-4/5/7/Smad2 signalling pathway. J Pharmacol Exp Therap 321: 431-438, 2007.
    • (2007) J Pharmacol Exp Therap , vol.321 , pp. 431-438
    • Ruiz, E.1    Redondo, S.2    Gordillo-Moscoso, A.3    Tejerina, T.4
  • 59
    • 52949132573 scopus 로고    scopus 로고
    • Keratinocyte-derived vascular endothelial growth factor biosynthesis represents a pleiotropic side effect of peroxisome proliferator-activated receptor-gamma agonist troglitazone but not rosiglitazone and involves activation of p38 mitogen-activated protein kinase: Implications for diabetes-impaired skin repair
    • Schiefelbein D, Seitz O, Goren I, Dissmann JP, Schmidt H, Bachmann M, Sader R, Geisslinger G, Pfeilschifter J, Frank S. Keratinocyte-derived vascular endothelial growth factor biosynthesis represents a pleiotropic side effect of peroxisome proliferator-activated receptor-gamma agonist troglitazone but not rosiglitazone and involves activation of p38 mitogen-activated protein kinase: implications for diabetes-impaired skin repair. Mol Pharmacol 74: 952-963, 2008.
    • (2008) Mol Pharmacol , vol.74 , pp. 952-963
    • Schiefelbein, D.1    Seitz, O.2    Goren, I.3    Dissmann, J.P.4    Schmidt, H.5    Bachmann, M.6    Sader, R.7    Geisslinger, G.8    Pfeilschifter, J.9    Frank, S.10
  • 60
    • 0034644539 scopus 로고    scopus 로고
    • Cell signalling by receptor tyrosine kinases
    • Schlessinger J. Cell signalling by receptor tyrosine kinases. Cell 103: 211-225, 2000.
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 63
    • 42549124085 scopus 로고    scopus 로고
    • Rosiglitazone induces caveolin-1 by PPARgammadependent and PPRE-independent mechanisms: The role of EGF receptor signalling and its effect on cancer cell drug resistance
    • Tencer L, Burgermeister E, Ebert MP, Liscovitch M. Rosiglitazone induces caveolin-1 by PPARgammadependent and PPRE-independent mechanisms: the role of EGF receptor signalling and its effect on cancer cell drug resistance. Anticancer Res 28: 895-906, 2008.
    • (2008) Anticancer Res , vol.28 , pp. 895-906
    • Tencer, L.1    Burgermeister, E.2    Ebert, M.P.3    Liscovitch, M.4
  • 66
    • 37549052177 scopus 로고    scopus 로고
    • Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes
    • Wang H, Qiang L, Farmer SR. Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes. Mol Cell Biol 28: 188-200, 2008.
    • (2008) Mol Cell Biol , vol.28 , pp. 188-200
    • Wang, H.1    Qiang, L.2    Farmer, S.R.3
  • 68
    • 54049158576 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor ligand MCC-555 suppresses intestinal polyps in ApcMin/mice via extracellular signal-regulated kinase and peroxisome proliferator-activated receptor- dependent pathways
    • Yamaguchi K, Cekanova M, McEntee MF, Yoon JH, Fischer SM, Renes IB, Van Seuningen I, Baek SJ. Peroxisome proliferator-activated receptor ligand MCC-555 suppresses intestinal polyps in ApcMin/mice via extracellular signal-regulated kinase and peroxisome proliferator-activated receptor- dependent pathways. Mol Cancer Therap 7: 2779-2787, 2008.
    • (2008) Mol Cancer Therap , vol.7 , pp. 2779-2787
    • Yamaguchi, K.1    Cekanova, M.2    McEntee, M.F.3    Yoon, J.H.4    Fischer, S.M.5    Renes, I.B.6    Van Seuningen, I.7    Baek, S.J.8
  • 69
    • 58349086542 scopus 로고    scopus 로고
    • Inhibition of peroxisome proliferator-activated receptor gamma increases estrogen receptordependent tumor specification
    • Yin Y, Yuan H, Zeng X, Kopelovich L, Glazer RI. Inhibition of peroxisome proliferator-activated receptor gamma increases estrogen receptordependent tumor specification. Cancer Res 69: 687-694, 2009.
    • (2009) Cancer Res , vol.69 , pp. 687-694
    • Yin, Y.1    Yuan, H.2    Zeng, X.3    Kopelovich, L.4    Glazer, R.I.5
  • 70
    • 68649123084 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-gamma inhibits transforming growth factor-beta1 induction of connective tissue growth factor and extracellular matrix in hypertrophic scar fibroblasts in vitro
    • Zhang GY, Cheng T, Zheng MH, Yi CG, Pan H, Li ZJ, Chen XL, Yu Q, Jiang LF, Zhou FY, Li XY, Yang JQ, Chu TG, Gao WY. Activation of peroxisome proliferator-activated receptor-gamma inhibits transforming growth factor-beta1 induction of connective tissue growth factor and extracellular matrix in hypertrophic scar fibroblasts in vitro. Arch Dermatol Res 301: 515-522, 2009.
    • (2009) Arch Dermatol Res , vol.301 , pp. 515-522
    • Zhang, G.Y.1    Cheng, T.2    Zheng, M.H.3    Yi, C.G.4    Pan, H.5    Li, Z.J.6    Chen, X.L.7    Yu, Q.8    Jiang, L.F.9    Zhou, F.Y.10    Li, X.Y.11    Yang, J.Q.12    Chu, T.G.13    Gao, W.Y.14


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.