메뉴 건너뛰기




Volumn 299, Issue 2, 2010, Pages

The importance of endothelin axis in initiation, progression, and therapy of ovarian cancer

Author keywords

Endothelin A receptor; Ovarian cancer; Targeted therapy

Indexed keywords

ATRASENTAN; CISPLATIN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; N (3 METHOXY 5 METHYL 2 PYRAZINYL) 2 [4 (1,3,4 OXADIAZOL 2 YL)PHENYL] 3 PYRIDINESULFONAMIDE; PACLITAXEL;

EID: 77955489086     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00304.2010     Document Type: Review
Times cited : (25)

References (79)
  • 3
    • 0032213023 scopus 로고    scopus 로고
    • Endothelins as autocrine regulators of tumor cell growth
    • Bagnato A, Catt KJ. Endothelins as autocrine regulators of tumor cell growth. Trends Endocrinol Metab 9: 378-383, 1998.
    • (1998) Trends Endocrinol Metab , vol.9 , pp. 378-383
    • Bagnato, A.1    Catt, K.J.2
  • 5
    • 34250691430 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in ovarian cancer progression: A crucial role for the endothelin axis
    • Bagnato A, Rosanò L. Epithelial-mesenchymal transition in ovarian cancer progression: a crucial role for the endothelin axis. Cells Tissues Organs 185: 85-94, 2007.
    • (2007) Cells Tissues Organs , vol.185 , pp. 85-94
    • Bagnato, A.1    Rosanò, L.2
  • 6
    • 0038407691 scopus 로고    scopus 로고
    • Emerging role of endothelin-1 in tumor angiogenesis
    • Bagnato A, Spinella F. Emerging role of endothelin-1 in tumor angiogenesis. Trends Endocrinol Metab 14: 44-50, 2003.
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 44-50
    • Bagnato, A.1    Spinella, F.2
  • 7
    • 29144470972 scopus 로고    scopus 로고
    • Emerging role of the endothelin axis in ovarian tumor progression
    • Bagnato A, Spinella F, Rosanò L. Emerging role of the endothelin axis in ovarian tumor progression. Endocr Relat Cancer 12: 761-772, 2005.
    • (2005) Endocr Relat Cancer , vol.12 , pp. 761-772
    • Bagnato, A.1    Spinella, F.2    Rosanò, L.3
  • 8
    • 48849097102 scopus 로고    scopus 로고
    • The endothelin axis in cancer: The promise and the challenges of molecularly targeted therapy
    • Bagnato A, Spinella F, Rosanò L. The endothelin axis in cancer: the promise and the challenges of molecularly targeted therapy. Can J Physiol Pharmacol 86: 473-484, 2008.
    • (2008) Can J Physiol Pharmacol , vol.86 , pp. 473-484
    • Bagnato, A.1    Spinella, F.2    Rosanò, L.3
  • 9
    • 0033083191 scopus 로고    scopus 로고
    • Expression of endothelin 1 and endothelin a receptor in ovarian carcinoma: Evidence for an autocrine role in tumor growth
    • Bagnato A, Salani D, Di Castro V, Wu-Wong JR, Tecce R, Nicotra MR, Venuti A, Natali PG. Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth. Cancer Res 59: 720-727, 1999.
    • (1999) Cancer Res , vol.59 , pp. 720-727
    • Bagnato, A.1    Salani, D.2    Di Castro, V.3    Wu-Wong, J.R.4    Tecce, R.5    Nicotra, M.R.6    Venuti, A.7    Natali, P.G.8
  • 10
    • 0030903110 scopus 로고    scopus 로고
    • Activation of mitogenic signaling by endothelin 1 in ovarian carcinoma cells
    • Bagnato A, Tecce R, Di Castro V, Catt KJ. Activation of mitogenic signaling by endothelin 1 in ovarian carcinoma cells. Cancer Res 57: 1306-1311, 1997.
    • (1997) Cancer Res , vol.57 , pp. 1306-1311
    • Bagnato, A.1    Tecce, R.2    Di Castro, V.3    Catt, K.J.4
  • 11
  • 12
    • 40349093189 scopus 로고    scopus 로고
    • Beta-arrestins: Multifunctional cellular mediators
    • Barki-Harrington L, Rockman HA. Beta-arrestins: multifunctional cellular mediators. Physiology 23: 17-22, 2008.
    • (2008) Physiology , vol.23 , pp. 17-22
    • Barki-Harrington, L.1    Rockman, H.A.2
  • 13
    • 67649440886 scopus 로고    scopus 로고
    • The biology of ovarian cancer: New opportunities for translation
    • Bast RC Jr, Hennessy B, Mills GB. The biology of ovarian cancer: new opportunities for translation. Nat Rev Cancer 9: 415-428, 2009.
    • (2009) Nat Rev Cancer , vol.9 , pp. 415-428
    • Bast Jr., R.C.1    Hennessy, B.2    Mills, G.B.3
  • 15
    • 0034010228 scopus 로고    scopus 로고
    • Receptor- And non-receptor-mediated clearance of big-endothelin and endothelin-1: Differential effects of acute and chronic ETA receptor blockade
    • Burkhardt M, Barton M, Shaw SG. Receptor- and non-receptor-mediated clearance of big-endothelin and endothelin-1: differential effects of acute and chronic ETA receptor blockade. J Hypertens 18: 273-279, 2000.
    • (2000) J Hypertens , vol.18 , pp. 273-279
    • Burkhardt, M.1    Barton, M.2    Shaw, S.G.3
  • 16
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 407: 249-257, 2000.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 19
    • 40349108549 scopus 로고    scopus 로고
    • Beta-arrestins and heterotrimeric G-proteins: Collaborators and competitors in signal transduction
    • Defea K. Beta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transduction. Br J Pharmacol 153 Suppl 1: S298-S309, 2008.
    • (2008) Br J Pharmacol , vol.153 , Issue.SUPPL. 1
    • Defea, K.1
  • 24
    • 3042734821 scopus 로고    scopus 로고
    • Association of E-cadherin and β-catenin immunoexpression with clinicopathologic features in primary ovarian carcinomas
    • DOI 10.1016/j.humpath.2004.01.024, PII S0046817704001078
    • Faleiro-Rodrigues C, Macedo-Pinto I, Pereira D, Ferreira VM, Lopes CS. Association of E-cadherin and beta-catenin immunoexpression with clinicopathologic features in primary ovarian carcinomas. Hum Pathol 35: 663-669, 2004. (Pubitemid 38881075)
    • (2004) Human Pathology , vol.35 , Issue.6 , pp. 663-669
    • Faleiro-Rodrigues, C.1    Macedo-Pinto, I.2    Pereira, D.3    Ferreira, V.M.4    Lopes, C.S.5
  • 27
    • 0034769736 scopus 로고    scopus 로고
    • Molecular pathology of cyclooxygenase-2 in cancer-induced angiogenesis
    • Fosslien E. Molecular pathology of cyclooxygenase-2 in cancer-induced angiogenesis. Ann Clin Lab Sci 31: 325-348, 2001.
    • (2001) Ann Clin Lab Sci , vol.31 , pp. 325-348
    • Fosslien, E.1
  • 28
    • 35648949978 scopus 로고    scopus 로고
    • β-Catenin signaling in biological control and cancer
    • Gavert N, and Ben-Ze'ev A. β-Catenin signaling in biological control and cancer. J Cell Biochem 102: 820-828, 2007.
    • (2007) J Cell Biochem , vol.102 , pp. 820-828
    • Gavert, N.1    Ben-Ze'ev, A.2
  • 29
    • 0037303203 scopus 로고    scopus 로고
    • Role of endothelin-1 in osteoblastic bone metastases
    • Guise TA, Yin JJ, Mohammad KS. Role of endothelin-1 in osteoblastic bone metastases. Cancer 97: 779-784, 2003.
    • (2003) Cancer , vol.97 , pp. 779-784
    • Guise, T.A.1    Yin, J.J.2    Mohammad, K.S.3
  • 30
    • 0037374468 scopus 로고    scopus 로고
    • Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer
    • Gupta RA, Tejada LV, Tong BJ, Das SK, Morrow JD, Dey SK, DuBois RN. Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer. Cancer Res 63: 906-911, 2003.
    • (2003) Cancer Res , vol.63 , pp. 906-911
    • Gupta, R.A.1    Tejada, L.V.2    Tong, B.J.3    Das, S.K.4    Morrow, J.D.5    Dey, S.K.6    DuBois, R.N.7
  • 31
    • 11144225205 scopus 로고    scopus 로고
    • Integrin-linked kinase: A cancer therapeutic target unique among its ILK
    • Hannigan G, Troussard AA, Dedhar S. Integrin-linked kinase: a cancer therapeutic target unique among its ILK. Nat Rev Cancer 5: 51-63, 2005.
    • (2005) Nat Rev Cancer , vol.5 , pp. 51-63
    • Hannigan, G.1    Troussard, A.A.2    Dedhar, S.3
  • 32
    • 77950188189 scopus 로고    scopus 로고
    • Pathway analysis of gene lists associated with platinum-based chemotherapy resistance in ovarian cancer: The big picture
    • Helleman J, Smid M, Jansen MP, van der Burg ME, Berns EM. Pathway analysis of gene lists associated with platinum-based chemotherapy resistance in ovarian cancer: the big picture. Gynecol Oncol 117: 170-176, 2010.
    • (2010) Gynecol Oncol , vol.117 , pp. 170-176
    • Helleman, J.1    Smid, M.2    Jansen, M.P.3    Van Der Burg, M.E.4    Berns, E.M.5
  • 33
    • 10944268101 scopus 로고    scopus 로고
    • Elevated expression of E-cadherin and alpha-, beta-, and gamma-catenins in metastatic lesions compared with primary epithelial ovarian carcinomas
    • Imai T, Horiuchi A, Shiozawa T, Osada R, Kikuchi N, Ohira S, Oka K, Konishi I. Elevated expression of E-cadherin and alpha-, beta-, and gamma-catenins in metastatic lesions compared with primary epithelial ovarian carcinomas. Hum Pathol 35: 1469-1476, 2004.
    • (2004) Hum Pathol , vol.35 , pp. 1469-1476
    • Imai, T.1    Horiuchi, A.2    Shiozawa, T.3    Osada, R.4    Kikuchi, N.5    Ohira, S.6    Oka, K.7    Konishi, I.8
  • 35
    • 16344379860 scopus 로고    scopus 로고
    • Neutral endopeptidase 2411/CD10 suppresses progressive potential in ovarian carcinoma in vitro and in vivo
    • Kajiyama H, Shibata K, Terauchi M, Morita T, Ino K, Mizutani S, Kikkawa F. Neutral endopeptidase 2411/CD10 suppresses progressive potential in ovarian carcinoma in vitro and in vivo. Clin Cancer Res 11: 1798-1808, 2005.
    • (2005) Clin Cancer Res , vol.11 , pp. 1798-1808
    • Kajiyama, H.1    Shibata, K.2    Terauchi, M.3    Morita, T.4    Ino, K.5    Mizutani, S.6    Kikkawa, F.7
  • 36
    • 35148825636 scopus 로고    scopus 로고
    • Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells
    • Kajiyama H, Shibata K, Terauchi M, Yamashita M, Ino K, Nawa A, Kikkawa F. Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells. Int J Oncol 31: 277-283, 2007.
    • (2007) Int J Oncol , vol.31 , pp. 277-283
    • Kajiyama, H.1    Shibata, K.2    Terauchi, M.3    Yamashita, M.4    Ino, K.5    Nawa, A.6    Kikkawa, F.7
  • 37
    • 0036473397 scopus 로고    scopus 로고
    • The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals
    • Luttrell LM, Lefkowitz RJ. The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. J Cell Sci 115: 455-65, 2002.
    • (2002) J Cell Sci , vol.115 , pp. 455-465
    • Luttrell, L.M.1    Lefkowitz, R.J.2
  • 38
    • 1942453322 scopus 로고    scopus 로고
    • Historical review: Endothelin
    • Masaki T. Historical review: Endothelin. Trends Pharmacol Sci 25: 219-224, 2004.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 219-224
    • Masaki, T.1
  • 39
    • 36249026290 scopus 로고    scopus 로고
    • The ovarian endothelin network: An evolving story
    • Meidan R, Nitzan L. The ovarian endothelin network: an evolving story. Trends Endocrinol Metab 18: 379-385, 2007.
    • (2007) Trends Endocrinol Metab , vol.18 , pp. 379-385
    • Meidan, R.1    Nitzan, L.2
  • 40
    • 18344380440 scopus 로고    scopus 로고
    • Ovarian cancer metastasis: Integrating insights from disparate model organisms
    • Naora H, Montell DJ. Ovarian cancer metastasis: integrating insights from disparate model organisms. Nat Rev Cancer 5: 355-366, 2005.
    • (2005) Nat Rev Cancer , vol.5 , pp. 355-366
    • Naora, H.1    Montell, D.J.2
  • 42
    • 34249289041 scopus 로고    scopus 로고
    • And bHLH factors in tumour progression: An alliance against the epithelial phenotype?
    • Peinado H, Olmeda D, Cano A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 7: 415-428, 2007.
    • (2007) Nat Rev Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3    Snail, Z.4
  • 43
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 9: 265-273, 2009.
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 44
    • 56449108554 scopus 로고    scopus 로고
    • Small interfering RNA molecules targeting endothelin-converting enzyme-1 inhibit endothelin-1 synthesis and the invasive phenotype of ovarian carcinoma cells
    • Rayhman O, Klipper E, Muller L, Davidson B, Reich R, Meidan R. Small interfering RNA molecules targeting endothelin-converting enzyme-1 inhibit endothelin-1 synthesis and the invasive phenotype of ovarian carcinoma cells. Cancer Res 68: 9265-78, 2008.
    • (2008) Cancer Res , vol.68 , pp. 9265-9278
    • Rayhman, O.1    Klipper, E.2    Muller, L.3    Davidson, B.4    Reich, R.5    Meidan, R.6
  • 45
    • 66849084071 scopus 로고    scopus 로고
    • Convergent pathways link the endothelin a receptor to the beta-catenin: The β-arrestin connection
    • Rosanò L, Bagnato A. Convergent pathways link the endothelin A receptor to the beta-catenin: the β-arrestin connection. Cell Cycle 8: 1462-1463, 2009.
    • (2009) Cell Cycle , vol.8 , pp. 1462-1463
    • Rosanò, L.1    Bagnato, A.2
  • 49
    • 34447128915 scopus 로고    scopus 로고
    • ZD4054, a specific antagonist of the endothelin a receptor, inhibits tumor growth and enhances paclitaxel activity in human ovarian carcinoma in vitro and in vivo
    • Rosanò L, Di Castro V, Spinella F, Nicotra MR, Natali PG, Bagnato A. ZD4054, a specific antagonist of the endothelin A receptor, inhibits tumor growth and enhances paclitaxel activity in human ovarian carcinoma in vitro and in vivo. Mol Cancer Ther 6: 2003-2011, 2007.
    • (2007) Mol Cancer Ther , vol.6 , pp. 2003-2011
    • Rosanò, L.1    Di Castro, V.2    Spinella, F.3    Nicotra, M.R.4    Natali, P.G.5    Bagnato, A.6
  • 50
    • 34447136110 scopus 로고    scopus 로고
    • Combined targeting of endothelin a receptor and epidermal growth factor receptor in ovarian cancer shows enhanced antitumor activity
    • Rosanò L, Di Castro V, Spinella F, Tortora G, Nicotra MR, Natali PG, Bagnato A. Combined targeting of endothelin A receptor and epidermal growth factor receptor in ovarian cancer shows enhanced antitumor activity. Cancer Res 67: 6351-6359, 2007.
    • (2007) Cancer Res , vol.67 , pp. 6351-6359
    • Rosanò, L.1    Di Castro, V.2    Spinella, F.3    Tortora, G.4    Nicotra, M.R.5    Natali, P.G.6    Bagnato, A.7
  • 53
    • 33646576837 scopus 로고    scopus 로고
    • Integrin-linked kinase functions as a downstream mediator of endothelin-1 to promote invasive behavior in ovarian carcinoma
    • Rosanò L, Spinella F, Di Castro V, Dedhar S, Nicotra MR, Natali PG, Bagnato A. Integrin-linked kinase functions as a downstream mediator of endothelin-1 to promote invasive behavior in ovarian carcinoma. Mol Cancer Ther 5: 833-842, 2006.
    • (2006) Mol Cancer Ther , vol.5 , pp. 833-842
    • Rosanò, L.1    Spinella, F.2    Di Castro, V.3    Dedhar, S.4    Nicotra, M.R.5    Natali, P.G.6    Bagnato, A.7
  • 54
    • 11144337535 scopus 로고    scopus 로고
    • Therapeutic targeting of the endothelin-A receptor in human ovarian carcinoma: Efficacy of cytotoxic agents is markedly enhanced by co-administration with atrasentan
    • Rosanò L, Spinella F, Di Castro V, Natali PG, Bagnato A. Therapeutic targeting of the endothelin-A receptor in human ovarian carcinoma: efficacy of cytotoxic agents is markedly enhanced by co-administration with atrasentan. J Cardiovasc Pharmacol 44 Suppl 1: S132-S135, 2004.
    • (2004) J Cardiovasc Pharmacol , vol.44 , Issue.SUPPL. 1
    • Rosanò, L.1    Spinella, F.2    Di Castro, V.3    Natali, P.G.4    Bagnato, A.5
  • 58
    • 0028154980 scopus 로고
    • Clinical review 53: The endocrinology of vasoactive peptides: synthesis to function
    • Rubin SA, Levin ER. Clinical review 53: The endocrinology of vasoactive peptides: synthesis to function. J Clin Endocrinol Metab 78: 6-10, 1994.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 6-10
    • Rubin, S.A.1    Levin, E.R.2
  • 61
    • 0033724661 scopus 로고    scopus 로고
    • Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo
    • Salani D, Taraboletti G, Rosanò L, Di Castro V, Borsotti P, Giavazzi R, Bagnato A. Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo. Am J Pathol 157: 1703-1711, 2000.
    • (2000) Am J Pathol , vol.157 , pp. 1703-1711
    • Salani, D.1    Taraboletti, G.2    Rosanò, L.3    Di Castro, V.4    Borsotti, P.5    Giavazzi, R.6    Bagnato, A.7
  • 64
    • 33744902332 scopus 로고    scopus 로고
    • Antitumor effect of green tea polyphenol epigallocatechin-3-gallate in ovarian carcinoma cells: Evidence for the endothelin-1 as a potential target
    • Spinella F, Rosanò L, Decandia S, Di Castro V, Albini A, Elia G, Natali PG, Bagnato A. Antitumor effect of green tea polyphenol epigallocatechin-3-gallate in ovarian carcinoma cells: evidence for the endothelin-1 as a potential target. Exp Biol Med (Maywood) 231: 1123-1127, 2006.
    • (2006) Exp Biol Med (Maywood) , vol.231 , pp. 1123-1127
    • Spinella, F.1    Rosanò, L.2    Decandia, S.3    Di Castro, V.4    Albini, A.5    Elia, G.6    Natali, P.G.7    Bagnato, A.8
  • 65
    • 33746038556 scopus 로고    scopus 로고
    • Green tea polyphenol epigallocatechin-3-gallate inhibits the endothelin axis and downstream signaling pathways in ovarian carcinoma
    • Spinella F, Rosanò L, Di Castro V, Decandia S, Albini A, Nicotra MR, Natali PG, Bagnato A. Green tea polyphenol epigallocatechin-3-gallate inhibits the endothelin axis and downstream signaling pathways in ovarian carcinoma. Mol Cancer Ther 5: 1483-1492, 2006.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1483-1492
    • Spinella, F.1    Rosanò, L.2    Di Castro, V.3    Decandia, S.4    Albini, A.5    Nicotra, M.R.6    Natali, P.G.7    Bagnato, A.8
  • 66
    • 0037008695 scopus 로고    scopus 로고
    • Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1alpha in ovarian carcinoma cells
    • Spinella F, Rosanò L, Di Castro V, Natali PG, Bagnato A. Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1alpha in ovarian carcinoma cells. J Biol Chem 277: 27850-27855, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 27850-27855
    • Spinella, F.1    Rosanò, L.2    Di Castro, V.3    Natali, P.G.4    Bagnato, A.5
  • 67
    • 8744250174 scopus 로고    scopus 로고
    • Endothelin-1- Induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion
    • Spinella F, Rosanò L, Di Castro V, Natali PG, Bagnato A. Endothelin-1- induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion. J Biol Chem 279: 46700-46705, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 46700-46705
    • Spinella, F.1    Rosanò, L.2    Di Castro, V.3    Natali, P.G.4    Bagnato, A.5
  • 68
    • 0142135067 scopus 로고    scopus 로고
    • Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells
    • Spinella F, Rosanò L, Di Castro V, Nicotra MR, Natali PG, Bagnato A. Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells. J Biol Chem 278: 41294-41301, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 41294-41301
    • Spinella, F.1    Rosanò, L.2    Di Castro, V.3    Nicotra, M.R.4    Natali, P.G.5    Bagnato, A.6
  • 69
    • 3242741855 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-1 and -2 expression by targeting the endothelin a receptor in human ovarian carcinoma cells
    • Spinella F, Rosanò L, Di Castro V, Nicotra MR, Natali PG, Bagnato A. Inhibition of cyclooxygenase-1 and -2 expression by targeting the endothelin a receptor in human ovarian carcinoma cells. Clin Cancer Res 10: 4670-4679, 2004.
    • (2004) Clin Cancer Res , vol.10 , pp. 4670-4679
    • Spinella, F.1    Rosanò, L.2    Di Castro, V.3    Nicotra, M.R.4    Natali, P.G.5    Bagnato, A.6
  • 70
    • 11144308977 scopus 로고    scopus 로고
    • Endothelin-1 stimulates cyclooxygenase-2 expression in ovarian cancer cells through multiple signaling pathways: Evidence for involvement of transactivation of the epidermal growth factor receptor
    • Spinella F, Rosanò L, Elia G, Di Castro V, Natali PG, Bagnato A. Endothelin-1 stimulates cyclooxygenase-2 expression in ovarian cancer cells through multiple signaling pathways: evidence for involvement of transactivation of the epidermal growth factor receptor. J Cardiovasc Pharmacol 44 Suppl 1: S140-S143, 2004.
    • (2004) J Cardiovasc Pharmacol , vol.44 , Issue.SUPPL. 1
    • Spinella, F.1    Rosanò, L.2    Elia, G.3    Di Castro, V.4    Natali, P.G.5    Bagnato, A.6
  • 71
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2: 442-454, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 72
    • 0003504049 scopus 로고    scopus 로고
    • Cyclooxygenase regulates angiogenesis induced by colon cancer cells
    • Tsujii M, Kawano S, Tsuji S, Sawaoka H, Hori M, DuBois RN. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 93: 705-716, 1998.
    • (1998) Cell , vol.93 , pp. 705-716
    • Tsujii, M.1    Kawano, S.2    Tsuji, S.3    Sawaoka, H.4    Hori, M.5    DuBois, R.N.6
  • 73
    • 0034081341 scopus 로고    scopus 로고
    • Gap junctional intercellular communication and connexin 43 expression in ovarian carcinoma
    • Umhauer S, Ruch RJ, Fanning J. Gap junctional intercellular communication and connexin 43 expression in ovarian carcinoma. Am J Obstet Gynecol 182: 999-1000, 2000.
    • (2000) Am J Obstet Gynecol , vol.182 , pp. 999-1000
    • Umhauer, S.1    Ruch, R.J.2    Fanning, J.3
  • 74
    • 0034665584 scopus 로고    scopus 로고
    • Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells
    • Vacca F, Bagnato A, Catt KJ, Tecce R. Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells. Cancer Res 60: 5310-5317, 2000.
    • (2000) Cancer Res , vol.60 , pp. 5310-5317
    • Vacca, F.1    Bagnato, A.2    Catt, K.J.3    Tecce, R.4
  • 76
    • 34447649922 scopus 로고    scopus 로고
    • Beta-arrestin-biased ligands at seven- Transmembrane receptors
    • Violin JD, Lefkowitz RJ. Beta-arrestin-biased ligands at seven- transmembrane receptors. Trends Pharmacol Sci 28: 416-22, 2007.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 416-422
    • Violin, J.D.1    Lefkowitz, R.J.2
  • 77
    • 17144449019 scopus 로고    scopus 로고
    • Expression of endothelin-1, endothelin-A, and endothelin-B receptor in human breast cancer and correlation with long-term follow-up
    • Wulfing P, Diallo R, Kersting C, Wulfing C, Poremba C, Rody A, Greb RR, Bocker W, Kiesel L. Expression of endothelin-1, endothelin-A, and endothelin-B receptor in human breast cancer and correlation with long-term follow-up. Clin Cancer Res 9: 4125-4131, 2003.
    • (2003) Clin Cancer Res , vol.9 , pp. 4125-4131
    • Wulfing, P.1    Diallo, R.2    Kersting, C.3    Wulfing, C.4    Poremba, C.5    Rody, A.6    Greb, R.R.7    Bocker, W.8    Kiesel, L.9
  • 78
    • 0027992642 scopus 로고
    • ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1
    • Xu D, Emoto N, Giaid A, Slaughter C, Kaw S, deWit D, Yanagisawa M. ECE-1: a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1. Cell 78: 473-485, 1994.
    • (1994) Cell , vol.78 , pp. 473-485
    • Xu, D.1    Emoto, N.2    Giaid, A.3    Slaughter, C.4    Kaw, S.5    DeWit, D.6    Yanagisawa, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.