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Volumn 14, Issue 1, 2003, Pages 44-50

Emerging role of endothelin-1 in tumor angiogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ATRASENTAN; CHELATING AGENT; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); CYCLOHEXIMIDE; CYTOKINE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; FOCAL ADHESION KINASE; G PROTEIN COUPLED RECEPTOR; GELATINASE A; GROWTH FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; NITRIC OXIDE; PHOSPHORAMIDON; PROTEINASE; SCLEROPROTEIN; TRANSITION ELEMENT; TYROSINE KINASE RECEPTOR; VASCULOTROPIN;

EID: 0038407691     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-2760(02)00010-3     Document Type: Review
Times cited : (126)

References (64)
  • 1
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D. and Weinberg, R.A. (2000) The hallmarks of cancer. Cell 100, 57-70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 0034470931 scopus 로고    scopus 로고
    • Targeting tumor vasculature with homing peptides from phage display
    • Ruoslati, E. (2000) Targeting tumor vasculature with homing peptides from phage display. Semin. Cancer Biol. 10, 435-442
    • (2000) Semin. Cancer Biol. , vol.10 , pp. 435-442
    • Ruoslati, E.1
  • 3
    • 0036488496 scopus 로고    scopus 로고
    • Specialization of tumor vasculature
    • Ruoslati, E. (2002) Specialization of tumor vasculature. Nat. Rev. Cancer 2, 83-90
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 83-90
    • Ruoslati, E.1
  • 4
    • 0037036136 scopus 로고    scopus 로고
    • Lymphatic metastasis in the absence of functional intratumor lymphatics
    • Padera, T.P. et al. (2002) Lymphatic metastasis in the absence of functional intratumor lymphatics. Science 296, 1883-1886
    • (2002) Science , vol.296 , pp. 1883-1886
    • Padera, T.P.1
  • 5
    • 0036527585 scopus 로고    scopus 로고
    • Molecular mechanisms of lymphangiogenesis in health and disease
    • Alitalo, K. and Carmeliet, P. (2002) Molecular mechanisms of lymphangiogenesis in health and disease. Cancer Cell 1, 219-227
    • (2002) Cancer Cell , vol.1 , pp. 219-227
    • Alitalo, K.1    Carmeliet, P.2
  • 6
    • 0032887340 scopus 로고    scopus 로고
    • Vascular channel formation by human melanoma cells in vivo and in vitro: Vasculogenic mimicry
    • Maniotis, A.J. et al. (1999) Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry. Am. J. Pathol. 155, 739-752
    • (1999) Am. J. Pathol. , vol.155 , pp. 739-752
    • Maniotis, A.J.1
  • 7
    • 0033839080 scopus 로고    scopus 로고
    • Opening between defective endothelial cells explain tumor vessel leakiness
    • Hashizume, H. et al. (2000) Opening between defective endothelial cells explain tumor vessel leakiness. Am. J. Pathol. 156, 1363-1380
    • (2000) Am. J. Pathol. , vol.156 , pp. 1363-1380
    • Hashizume, H.1
  • 8
    • 0035972251 scopus 로고    scopus 로고
    • Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis
    • Hellstrom, M. et al. (2001) Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J. Cell Biol. 153, 543-553
    • (2001) J. Cell Biol. , vol.153 , pp. 543-553
    • Hellstrom, M.1
  • 9
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet, P. and Jain, R.K. (2000) Angiogenesis in cancer and other diseases. Nature 407, 249-257
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 10
    • 0032710319 scopus 로고    scopus 로고
    • Clinical applications of angiogenic growth factors and their inhibitors
    • Ferrara, N. and Alitalo, K. (1999) Clinical applications of angiogenic growth factors and their inhibitors. Nat. Med. 5, 1359-1364
    • (1999) Nat. Med. , vol.5 , pp. 1359-1364
    • Ferrara, N.1    Alitalo, K.2
  • 11
    • 0035952713 scopus 로고    scopus 로고
    • Angiogenesis and G-protein-coupled receptors: Signals that bridge the gap
    • Richard, D.E. et al. (2001) Angiogenesis and G-protein-coupled receptors: signals that bridge the gap. Oncogene 20, 1556-1562
    • (2001) Oncogene , vol.20 , pp. 1556-1562
    • Richard, D.E.1
  • 12
    • 0027984808 scopus 로고
    • Endothelins: Molecular biology, biochemistry, pharmacology, physiology and pathophysiology
    • Rubanyi, G.M. and Polokoff, M.A. (1994) Endothelins: molecular biology, biochemistry, pharmacology, physiology and pathophysiology. Pharmacol. Rev. 46, 325-415
    • (1994) Pharmacol. Rev. , vol.46 , pp. 325-415
    • Rubanyi, G.M.1    Polokoff, M.A.2
  • 13
    • 0026601830 scopus 로고
    • Autocrine receptors for endothelins in the primary culture of endothelial cells of human umbilical vein
    • Fujitani, Y. et al. (1992) Autocrine receptors for endothelins in the primary culture of endothelial cells of human umbilical vein. FEBS Lett. 298, 79-83
    • (1992) FEBS Lett. , vol.298 , pp. 79-83
    • Fujitani, Y.1
  • 14
    • 0026496221 scopus 로고
    • Endothelin-1 stimulates its own synthesis in human endothelial cells
    • Saijonmaa, O. et al. (1992) Endothelin-1 stimulates its own synthesis in human endothelial cells. Biochem. Biophys. Res. Commun. 188, 286-291
    • (1992) Biochem. Biophys. Res. Commun. , vol.188 , pp. 286-291
    • Saijonmaa, O.1
  • 15
    • 0031799003 scopus 로고    scopus 로고
    • Endothelin B receptors on human endothelial and smooth muscle cells show equivalent binding pharmacology
    • Flynn, M.A. et al. (1998) Endothelin B receptors on human endothelial and smooth muscle cells show equivalent binding pharmacology. J. Cardiovasc. Pharmacol. 32, 106-116
    • (1998) J. Cardiovasc. Pharmacol. , vol.32 , pp. 106-116
    • Flynn, M.A.1
  • 16
    • 0028175913 scopus 로고
    • 125I]-ET-1 binding to the atherosclerotic human coronary artery
    • 125I]-ET-1 binding to the atherosclerotic human coronary artery. Br. J. Pharmacol. 112, 386-389
    • (1994) Br. J. Pharmacol. , vol.112 , pp. 386-389
    • Dashwood, M.R.1
  • 17
    • 0030758775 scopus 로고    scopus 로고
    • Vasoactive peptides modulate vascular endothelial cell growth factor production and endothelial cell proliferation and invasion
    • Pedram, A. et al. (1997) Vasoactive peptides modulate vascular endothelial cell growth factor production and endothelial cell proliferation and invasion. J. Biol. Chem. 272, 17097-17103
    • (1997) J. Biol. Chem. , vol.272 , pp. 17097-17103
    • Pedram, A.1
  • 18
    • 0030903110 scopus 로고    scopus 로고
    • Activation of mitogenic signaling by endothelin-1 in ovarian carcinoma cells
    • Bagnato, A. et al. (1997) Activation of mitogenic signaling by endothelin-1 in ovarian carcinoma cells. Cancer Res. 57, 1306-1311
    • (1997) Cancer Res. , vol.57 , pp. 1306-1311
    • Bagnato, A.1
  • 19
    • 0030044360 scopus 로고    scopus 로고
    • Role of transactivation of the EGF receptor in signal by G-protein-coupled receptors
    • Daub, H. et al. (1996) Role of transactivation of the EGF receptor in signal by G-protein-coupled receptors. Nature 379, 557-559
    • (1996) Nature , vol.379 , pp. 557-559
    • Daub, H.1
  • 20
    • 0034665584 scopus 로고    scopus 로고
    • Transactivation of the epidermal growth factor receptor in endothelin-l-induced mitogenic signaling in human ovarian carcinoma cells
    • Vacca, F. et al. (2000) Transactivation of the epidermal growth factor receptor in endothelin-l-induced mitogenic signaling in human ovarian carcinoma cells. Cancer Res. 60, 5310-5317
    • (2000) Cancer Res. , vol.60 , pp. 5310-5317
    • Vacca, F.1
  • 21
    • 0036176126 scopus 로고    scopus 로고
    • Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: Requirement for AKT activation
    • Del Bufalo, D. et al. (2002) Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for AKT activation. Mol. Pharmacol. 61, 524-532
    • (2002) Mol. Pharmacol. , vol.61 , pp. 524-532
    • Del Bufalo, D.1
  • 22
    • 0028816703 scopus 로고
    • Proliferation and migration of endothelial cells is promoted by endothelins via activation of ETB receptors
    • Morbidelli, L. et al. (1995) Proliferation and migration of endothelial cells is promoted by endothelins via activation of ETB receptors. Am. J. Physiol. 269, H685-H695
    • (1995) Am. J. Physiol. , vol.269
    • Morbidelli, L.1
  • 23
    • 0031026589 scopus 로고    scopus 로고
    • Permissive role of nitric oxide in endothelininduced migration of endothelial cells
    • Noiri, E. et al. (1997) Permissive role of nitric oxide in endothelininduced migration of endothelial cells. J. Biol. Chem. 272, 1747-1752
    • (1997) J. Biol. Chem. , vol.272 , pp. 1747-1752
    • Noiri, E.1
  • 24
    • 0031886882 scopus 로고    scopus 로고
    • Podokinesis in endothelial cell migration: Role of NO
    • Noiri, E. et al. (1998) Podokinesis in endothelial cell migration: role of NO. Am. J. Physiol. 274, C236-C244
    • (1998) Am. J. Physiol. , vol.274
    • Noiri, E.1
  • 25
    • 0027501135 scopus 로고
    • Endothelin-3 mediated proliferation of wounded human umbilical vein endothelial cells
    • Wren, A. et al. (1993) Endothelin-3 mediated proliferation of wounded human umbilical vein endothelial cells. Biochem. Biophys. Res. Commun. 196, 369-375
    • (1993) Biochem. Biophys. Res. Commun. , vol.196 , pp. 369-375
    • Wren, A.1
  • 26
    • 0032822842 scopus 로고    scopus 로고
    • Angiogenesis in cancer: The role of endothelin-1
    • Dawas, K. et al. (1999) Angiogenesis in cancer: the role of endothelin-1. Ann. R. Coll. Surg. Engl. 81, 306-310
    • (1999) Ann. R. Coll. Surg. Engl. , vol.81 , pp. 306-310
    • Dawas, K.1
  • 27
    • 0033724661 scopus 로고    scopus 로고
    • Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo
    • Salani, D. et al. (2000) Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo. Am. J. Pathol. 157, 1703-1711
    • (2000) Am. J. Pathol. , vol.157 , pp. 1703-1711
    • Salani, D.1
  • 28
    • 0035101532 scopus 로고    scopus 로고
    • Endothelin receptor blockade inhibits proliferation of Kaposi's sarcoma cells
    • Bagnato, A. et al. (2001) Endothelin receptor blockade inhibits proliferation of Kaposi's sarcoma cells. Am. J. Pathol. 158, 841-847
    • (2001) Am. J. Pathol. , vol.158 , pp. 841-847
    • Bagnato, A.1
  • 29
    • 0033561341 scopus 로고    scopus 로고
    • Human erythropoietin induces a proangiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo
    • Ribatti, D. et al. (1999) Human erythropoietin induces a proangiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo. Blood 93, 2627-2639
    • (1999) Blood , vol.93 , pp. 2627-2639
    • Ribatti, D.1
  • 30
    • 0030022427 scopus 로고    scopus 로고
    • Comparative studies of the angiogenic activity of vasoactive intestinal peptide, endothelins-1 and -3 and angiotensin II in a rat sponge model
    • Hu, D. et al. (1996) Comparative studies of the angiogenic activity of vasoactive intestinal peptide, endothelins-1 and -3 and angiotensin II in a rat sponge model. Br. J. Pharmacol. 117, 545-551
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 545-551
    • Hu, D.1
  • 32
    • 0035217115 scopus 로고    scopus 로고
    • Endothelin-1, a regulator of angiogenesis in the chick chorioallantoic membrane
    • Cruz, A. et al. (2001) Endothelin-1, a regulator of angiogenesis in the chick chorioallantoic membrane. J. Vasc. Res. 38, 536-545
    • (2001) J. Vasc. Res. , vol.38 , pp. 536-545
    • Cruz, A.1
  • 33
    • 0030667291 scopus 로고    scopus 로고
    • Endothelin-1 as an autocrine/paracrine apoptosis survival factor for endothelial cells
    • Shichiri, M. et al. (1997) Endothelin-1 as an autocrine/paracrine apoptosis survival factor for endothelial cells. Hypertension 30, 1198-1203
    • (1997) Hypertension , vol.30 , pp. 1198-1203
    • Shichiri, M.1
  • 34
    • 0031438146 scopus 로고    scopus 로고
    • Endothelin attenuates apoptosis in human smooth muscle cells
    • Wu-Wong, J.R. et al. (1997) Endothelin attenuates apoptosis in human smooth muscle cells. Biochem. J. 328, 733-737
    • (1997) Biochem. J. , vol.328 , pp. 733-737
    • Wu-Wong, J.R.1
  • 35
    • 0034031776 scopus 로고    scopus 로고
    • Endothelin-1 inhibits apoptosis of vascular smooth muscle cells induced by nitric oxide and serum-deprivation via MAP kinase pathway
    • Shichiri, M. et al. (2000) Endothelin-1 inhibits apoptosis of vascular smooth muscle cells induced by nitric oxide and serum-deprivation via MAP kinase pathway. Arterioscler. Thromb. Vasc. Biol. 20, 989-997
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 989-997
    • Shichiri, M.1
  • 36
    • 0034648793 scopus 로고    scopus 로고
    • Vascular-specific growth factors and blood vessel formation
    • Yancopoulos, G.D. et al. (2000) Vascular-specific growth factors and blood vessel formation. Nature 407, 242-248
    • (2000) Nature , vol.407 , pp. 242-248
    • Yancopoulos, G.D.1
  • 37
    • 0031878495 scopus 로고    scopus 로고
    • Stimulatory interaction between vascular endothelial growth factor and endothelin-1 on each gene expression
    • Matsuura, A. et al. (1998) Stimulatory interaction between vascular endothelial growth factor and endothelin-1 on each gene expression. Hypertension 32, 89-95
    • (1998) Hypertension , vol.32 , pp. 89-95
    • Matsuura, A.1
  • 38
    • 0032479222 scopus 로고    scopus 로고
    • Hypoxia and endothelin-1 induce VEGF production in human vascular smooth muscle cells
    • Okuda, Y. et al. (1998) Hypoxia and endothelin-1 induce VEGF production in human vascular smooth muscle cells. Life Sci. 63, 477-484
    • (1998) Life Sci. , vol.63 , pp. 477-484
    • Okuda, Y.1
  • 39
    • 0035918213 scopus 로고    scopus 로고
    • Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1 activator protein1, GATA-2 and p300/CBP
    • Yamashita, K. (2001) Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1 activator protein1, GATA-2 and p300/CBP. J. Biol. Chem. 276, 12645-12653
    • (2001) J. Biol. Chem. , vol.276 , pp. 12645-12653
    • Yamashita, K.1
  • 40
    • 0033978387 scopus 로고    scopus 로고
    • Chemokine and cytokine-induced expression of endothelin-1 and endothelin converting enzyme 1 in endothelial cells
    • Molet, S. et al. (2000) Chemokine and cytokine-induced expression of endothelin-1 and endothelin converting enzyme 1 in endothelial cells. J. Aller. Clin. Immunol. 105, 333-338
    • (2000) J. Aller. Clin. Immunol. , vol.105 , pp. 333-338
    • Molet, S.1
  • 41
    • 0032213023 scopus 로고    scopus 로고
    • Endothelins as autocrine regulators of tumor cell growth
    • Bagnato, A. and Catt, K.J. (1998) Endothelins as autocrine regulators of tumor cell growth. Trends Endocrinol. Metab. 9, 378-383
    • (1998) Trends Endocrinol. Metab. , vol.9 , pp. 378-383
    • Bagnato, A.1    Catt, K.J.2
  • 42
    • 0013084674 scopus 로고    scopus 로고
    • The endothelin receptor: A novel target for anticancer therapy
    • Pirtskhalaishvili, G. and Nelson, J.B. (2002) The endothelin receptor: a novel target for anticancer therapy. Am. J. Cancer 1, 3-8
    • (2002) Am. J. Cancer , vol.1 , pp. 3-8
    • Pirtskhalaishvili, G.1    Nelson, J.B.2
  • 43
    • 0030717622 scopus 로고    scopus 로고
    • Correlation of endothelin-1 and transforming growth factor β1 with malignancy and vascularity in human gliomas
    • Stiles, J.D. et al. (1997) Correlation of endothelin-1 and transforming growth factor β1 with malignancy and vascularity in human gliomas. J. Neuropathol. Exp. Neurol. 56, 435-439
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 435-439
    • Stiles, J.D.1
  • 44
    • 20244377662 scopus 로고    scopus 로고
    • The endothelin system in human glioblastoma
    • Egidy, G. et al. (2000) The endothelin system in human glioblastoma. Lab. Invest. 80, 1681-1689
    • (2000) Lab. Invest. , vol.80 , pp. 1681-1689
    • Egidy, G.1
  • 45
    • 0033637122 scopus 로고    scopus 로고
    • Modulation of human colon tumor-stromal interactions by the endothelin system
    • Egidy, G. et al. (2000) Modulation of human colon tumor-stromal interactions by the endothelin system. Am. J. Pathol. 157, 1863-1874
    • (2000) Am. J. Pathol. , vol.157 , pp. 1863-1874
    • Egidy, G.1
  • 46
    • 0035977181 scopus 로고    scopus 로고
    • Increased endothelin-1 in colorectal cancer and reduction of tumor growth by ETA receptor antagonist
    • Asham, E. et al. (2001) Increased endothelin-1 in colorectal cancer and reduction of tumor growth by ETA receptor antagonist. Br. J. Cancer 85, 1759-1763
    • (2001) Br. J. Cancer , vol.85 , pp. 1759-1763
    • Asham, E.1
  • 47
    • 0036283452 scopus 로고    scopus 로고
    • Endothelin-1 as a target for therapeutic intervention in prostate cancer
    • Kopetz, E.S. et al. (2002) Endothelin-1 as a target for therapeutic intervention in prostate cancer. Invest. New Drugs 20, 173-182
    • (2002) Invest. New Drugs , vol.20 , pp. 173-182
    • Kopetz, E.S.1
  • 48
    • 0034095640 scopus 로고    scopus 로고
    • Endothelin-1 induces vascular endothelial growth factor synthesis in osteoblasts. Involvement of p38 mitogenactivated protein kinase
    • Kozawa, O. et al. (2000) Endothelin-1 induces vascular endothelial growth factor synthesis in osteoblasts. Involvement of p38 mitogenactivated protein kinase. Cell. Signal. 12, 375-380
    • (2000) Cell. Signal. , vol.12 , pp. 375-380
    • Kozawa, O.1
  • 49
    • 0034077408 scopus 로고    scopus 로고
    • Studies on the expression of endothelin, its receptor subtypes and converting enzymes in lung cancer and in human bronchial epithelium
    • Ahmed, S.I. et al. (2000) Studies on the expression of endothelin, its receptor subtypes and converting enzymes in lung cancer and in human bronchial epithelium. Am. J. Respir. Cell Mol. Biol. 22, 422-431
    • (2000) Am. J. Respir. Cell Mol. Biol. , vol.22 , pp. 422-431
    • Ahmed, S.I.1
  • 50
    • 0035722931 scopus 로고    scopus 로고
    • Role of endothelin-1 in lung disease
    • Fagan, K.A. et al. (2001) Role of endothelin-1 in lung disease. Respir. Res. 2, 90-101
    • (2001) Respir. Res. , vol.2 , pp. 90-101
    • Fagan, K.A.1
  • 51
    • 0034967245 scopus 로고    scopus 로고
    • Tissue-specific gene therapy directed to tumor angiogenesis
    • Varda-Bloom, N. (2001) Tissue-specific gene therapy directed to tumor angiogenesis. Gene Ther. 8, 819-827
    • (2001) Gene Ther. , vol.8 , pp. 819-827
    • Varda-Bloom, N.1
  • 52
    • 0033083191 scopus 로고    scopus 로고
    • Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: Evidence for an autocrine role in tumor growth
    • Bagnato, A. et al. (1999) Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth. Cancer Res. 59, 720-727
    • (1999) Cancer Res. , vol.59 , pp. 720-727
    • Bagnato, A.1
  • 53
    • 0033724657 scopus 로고    scopus 로고
    • Role of endothelin-1 in neovascularization of ovarian carcinoma
    • Salani, D. et al. (2000) Role of endothelin-1 in neovascularization of ovarian carcinoma. Am. J. Pathol. 157, 1537-1547
    • (2000) Am. J. Pathol. , vol.157 , pp. 1537-1547
    • Salani, D.1
  • 54
    • 0037008695 scopus 로고    scopus 로고
    • Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1α in ovarian carcinoma cells
    • Spinella, S. et al. (2002) Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1α in ovarian carcinoma cells. J. Biol. Chem. 277, 27850-27855
    • (2002) J. Biol. Chem. , vol.277 , pp. 27850-27855
    • Spinella, S.1
  • 55
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia: A key regulatory factor in tumor growth
    • Harris, A.L. (2002) Hypoxia: a key regulatory factor in tumor growth. Nat. Rev. Cancer 2, 38-47
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 56
    • 0036216692 scopus 로고    scopus 로고
    • HIF-1 and tumor progression: Pathophysiology and therapeutics
    • Semenza, G.L. (2002) HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol. Med. 8, 562-567
    • (2002) Trends Mol. Med. , vol.8 , pp. 562-567
    • Semenza, G.L.1
  • 57
    • 0034896068 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1α in epithelial ovarian tumors: Its impact on prognosis and on response to chemotherapy
    • Birner, P. et al. (2001) Expression of hypoxia-inducible factor 1α in epithelial ovarian tumors: its impact on prognosis and on response to chemotherapy. Clin. Cancer Res. 7, 1661-1668
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1661-1668
    • Birner, P.1
  • 58
    • 0038228435 scopus 로고
    • Autocrine actions of endothelin-1 as a growth factor in human ovarian carcinoma cells
    • Bagnato, A. et al. (1995) Autocrine actions of endothelin-1 as a growth factor in human ovarian carcinoma cells. Clin. Cancer Res. 59, 720-727
    • (1995) Clin. Cancer Res. , vol.59 , pp. 720-727
    • Bagnato, A.1
  • 59
    • 0035890357 scopus 로고    scopus 로고
    • Endothelin-1 induces tumor proteinase activation and invasiveness of ovarian carcinoma cells
    • Rosanò, L. et al. (2001) Endothelin-1 induces tumor proteinase activation and invasiveness of ovarian carcinoma cells. Cancer Res. 61, 8340-8346
    • (2001) Cancer Res. , vol.61 , pp. 8340-8346
    • Rosanò, L.1
  • 60
    • 0034076139 scopus 로고    scopus 로고
    • A selective endothelin antagonist, in humans
    • A selective endothelin antagonist, in humans. Br. J. Clin. Pharmacol. 49, 562-573
    • (2001) Br. J. Clin. Pharmacol. , vol.49 , pp. 562-573
    • Verhaar, M.C.1
  • 61
    • 0036670301 scopus 로고    scopus 로고
    • ABT 627, a potent endothelin receptor A antagonist, inhibits ovarian carcinoma growth in vitro
    • Salani, D. et al. (2002) ABT 627, a potent endothelin receptor A antagonist, inhibits ovarian carcinoma growth in vitro. Clin. Sci. 103, 318S-321S
    • (2002) Clin. Sci. , vol.103
    • Salani, D.1
  • 62
    • 0001569259 scopus 로고    scopus 로고
    • Inhibition of tumor growth and angiogenesis by ABT-627 an endothelin receptor A antagonist in ovarian carcinoma xenografts
    • Rosanò, L. et al. (2000) Inhibition of tumor growth and angiogenesis by ABT-627 an endothelin receptor A antagonist in ovarian carcinoma xenografts. Proc. Am. Assoc. Cancer Res. 41, 327
    • (2000) Proc. Am. Assoc. Cancer Res. , vol.41 , pp. 327
    • Rosanò, L.1
  • 63
    • 0037006093 scopus 로고    scopus 로고
    • The embryonic-like properties of aggressive human tumor cells
    • Sood, A.K. et al. (2002) The embryonic-like properties of aggressive human tumor cells. J. Soc. Gynecol. Investig. 9, 2-9
    • (2002) J. Soc. Gynecol. Investig. , vol.9 , pp. 2-9
    • Sood, A.K.1
  • 64
    • 0037089676 scopus 로고    scopus 로고
    • Atrasentan, an endothelin-receptor antagonist for refractory adenocarcinomas: Safety and pharmacokinetics
    • Carducci, M.A. et al. (2002) Atrasentan, an endothelin-receptor antagonist for refractory adenocarcinomas: safety and pharmacokinetics. J. Clin. Oncol. 20, 2171-2180
    • (2002) J. Clin. Oncol. , vol.20 , pp. 2171-2180
    • Carducci, M.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.