메뉴 건너뛰기




Volumn 66, Issue 34, 2010, Pages 6749-6753

An approach for the enantioselective synthesis of biologically active furanones from a Morita-Baylis-Hillman adduct

Author keywords

Anti Inflammatory; Asymmetric synthesis; Furanones; Morita Baylis Hillman; Palladium

Indexed keywords

2 [4 (METHYLSULFANYL) BENZYLIDENE] BUTAN 1 OL; 2 ETHYL 2 METHYL 3 [4 (METHYLSULFONYL) PHENYL] OXIRANE; 2 HYDROXY 2 METHYL 1 [4 (METHYLSULFONYL) PHENYL] BUTAN 1 ONE; 2 METHYL 1 [4 (METHYLSULFONYL) PHENYL] 1 OXOBUTAN 2 YL (PROPAN 2 YLOXY) ACETATE; 5 ETHYL 3 ISOPROPOXY 5 METHYL 4 [4 (METHYLSULFONYL) PHENYL] FURAN 2(5H) ONE; 5,5 DIMETHYL 3 (2 PROPOXY) 4 METHANESULFONYLPHENYL 2(5H) FURANONE; [2 ETHYL 3 [4 (METHYLSULFONYL) PHENYL] OXIRAN 2YL] METHANOL; ACETIC ACID DERIVATIVE; ACRYLIC ACID DERIVATIVE; BUTYRIC ACID; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; EPOXIDE; ETHYLENE OXIDE DERIVATIVE; FURANONE DERIVATIVE; METHANOL DERIVATIVE; METHYL 2 [(ACETYLOXY) METHYL [4 (METHYLSULFANYL) PHENYL] METHYL] ACRYLATE; METHYL 2 [4 (METHYLSULFANYL) BENZYLIDENE] BUTANOATE; METHYL 2 [YDROXY [4 (METHYLSULFANYL) PHENYL] METHYL] ACRYLATE; PALLADIUM; ROFECOXIB; UNCLASSIFIED DRUG;

EID: 77955467203     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2010.06.077     Document Type: Article
Times cited : (7)

References (52)
  • 1
    • 0003845213 scopus 로고    scopus 로고
    • J.E. Gallin, R. Snyderman, 3rd ed. Lippincott William & Wilkins Washington, DC
    • J.E. Gallin, R. Snyderman, Inflammation: Basic Principles and Clinical Correlates 3rd ed. 1999 Lippincott William & Wilkins Washington, DC
    • (1999) Inflammation: Basic Principles and Clinical Correlates
  • 2
    • 0004329965 scopus 로고    scopus 로고
    • K. Ley, American Physiological Sociey Bethesda
    • K. Ley, Physiology of Inflammation 2001 American Physiological Sociey Bethesda
    • (2001) Physiology of Inflammation
  • 10
    • 77955472384 scopus 로고    scopus 로고
    • note
    • Vioxx ís a registered trademark of Merck while Celebrex is a registered trademark of Pfizer.
  • 19
    • 77955470124 scopus 로고    scopus 로고
    • Chem. Abstr. 127 1997 384238
    • (1997) Chem. Abstr. , vol.127 , pp. 384238
  • 38
    • 77955473420 scopus 로고    scopus 로고
    • The double bond configuration was determined as being E by NOE experiments
    • The double bond configuration was determined as being E by NOE experiments
  • 40
    • 77955466691 scopus 로고    scopus 로고
    • note
    • The enantiomeric excess of epoxide 3 was determined by chiral HPLC using a Chiralcel column OJ-H, 0.46 cm of diameter×25 cm purchased by DAICEL Chemical Eluent: hexanes/isopropyl alcohol 35%, isocratic elution.
  • 41
    • 4143088133 scopus 로고    scopus 로고
    • Y. Shi Acc. Chem. Res. 37 2004 488 496 and references cited therein
    • (2004) Acc. Chem. Res. , vol.37 , pp. 488-496
    • Shi, Y.1
  • 51
    • 77955473326 scopus 로고    scopus 로고
    • PCT WO 2006/005682 A2 01.19.
    • Sommerlade, R.H.; Richter, I. PCT WO 2006/005682 A2 01.19.2006.
    • (2006)
    • Sommerlade, R.H.1    Richter, I.2
  • 52
    • 0141628842 scopus 로고    scopus 로고
    • 2-Isoproxy acetic acid can be easily prepared from commercially available methyl bromoacetate in two steps and 92% overall yield. See: S. Padakanti, M. Pal, and K.R. Yeleswaparu Tetrahedron 59 2003 7915 7920
    • (2003) Tetrahedron , vol.59 , pp. 7915-7920
    • Padakanti, S.1    Pal, M.2    Yeleswaparu, K.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.