Atrogin-1 affects muscle protein synthesis and degradation when energy metabolism is impaired by the antidiabetes drug berberine

Diabetes

Volumn 59, Issue 8, 2010, Pages 1879-1889

  Wang, Huiling ^a   Liu, Dajun ^b   Cao, Peirang ^c   Lecker, Stewart ^c,d   Hu, Zhaoyong ^e  

^a Jimin Hospital   (China)

^b CHINA MEDICAL UNIVERSITY   (China)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATROGIN 1; BERBERINE; FORKHEAD TRANSCRIPTION FACTOR; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; LAMININ; MESSENGER RNA; MUSCLE PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN KINASE B; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ELF 3 F; TRANSCRIPTION FACTOR FOXO; TYROSINE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG MECHANISM; ENERGY METABOLISM; GENE OVEREXPRESSION; MOUSE; MUSCLE ATROPHY; MUSCLE METABOLISM; MYOTUBE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

ANIMALS; BERBERINE; DNA PRIMERS; ENERGY METABOLISM; GENE EXPRESSION REGULATION; HYPOGLYCEMIC AGENTS; MICE; MICE, INBRED STRAINS; MUSCLE FIBERS, SKELETAL; MUSCLE PROTEINS; MUSCLE, SKELETAL; MUSCULAR ATROPHY; MYOBLASTS; POLYMERASE CHAIN REACTION; RNA; SKP CULLIN F-BOX PROTEIN LIGASES; TRANSCRIPTION FACTORS;

EID: 77955375187     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db10-0207     Document Type: Article

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