-
1
-
-
33644779799
-
Costimulation blockade of both inducible costimulator and CD40 ligand induces dominant tolerance to islet allografts and prevents spontaneous autoimmune diabetes in the NOD mouse
-
DOI 10.2337/diabetes.55.1.27
-
Nanji SA, Hancock WW, Luo B, Schur CD, Pawlick RL, Zhu LF, Anderson CC, Shapiro AM. Costimulation blockade of both inducible costimulator and CD40 ligand induces dominant tolerance to islet allografts and prevents spontaneous autoimmune diabetes in the NOD mouse. Diabetes 2006;55:27-33 (Pubitemid 43343296)
-
(2006)
Diabetes
, vol.55
, Issue.1
, pp. 27-33
-
-
Nanji, S.A.1
Hancock, W.W.2
Luo, B.3
Schur, C.D.4
Pawlick, R.L.5
Lin, F.Z.6
Anderson, C.C.7
Shapiro, A.M.J.8
-
2
-
-
33845359383
-
Costimulatory molecules as targets for the induction of transplantation tolerance
-
DOI 10.2174/156652406779010812
-
Alegre ML, Najafian N. Costimulatory molecules as targets for the induction of transplantation tolerance. Curr Mol Med 2006;6:843-857 (Pubitemid 44883936)
-
(2006)
Current Molecular Medicine
, vol.6
, Issue.8
, pp. 843-857
-
-
Alegre, M.-L.1
Najafian, N.2
-
3
-
-
0344984420
-
T-cell costimulatory pathways in allograft rejection and tolerance
-
Rothstein DM, Sayegh MH. T-cell costimulatory pathways in allograft rejection and tolerance. Immunol Rev 2003;196:85-108
-
(2003)
Immunol Rev
, vol.196
, pp. 85-108
-
-
Rothstein, D.M.1
Sayegh, M.H.2
-
4
-
-
25444508245
-
T-cell costimulatory pathways in allograft rejection and tolerance
-
Clarkson MR, Sayegh MH. T-cell costimulatory pathways in allograft rejection and tolerance. Transplantation 2005;80:555-563
-
(2005)
Transplantation
, vol.80
, pp. 555-563
-
-
Clarkson, M.R.1
Sayegh, M.H.2
-
5
-
-
33645846313
-
Tissue expression of PD-L1 mediates peripheral T cell tolerance
-
Keir ME, Liang SC, Guleria I, Latchman YE, Qipo A, Albacker LA, Koulmanda M, Freeman GJ, Sayegh MH, Sharpe AH. Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med 2006;203:883-895
-
(2006)
J Exp Med
, vol.203
, pp. 883-895
-
-
Keir, M.E.1
Liang, S.C.2
Guleria, I.3
Latchman, Y.E.4
Qipo, A.5
Albacker, L.A.6
Koulmanda, M.7
Freeman, G.J.8
Sayegh, M.H.9
Sharpe, A.H.10
-
6
-
-
0037152153
-
Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues
-
Ishida M, Iwai Y, Tanaka Y, Okazaki T, Freeman GJ, Minato N, Honjo T. Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues. Immunol Lett 2002;84:57-62
-
(2002)
Immunol Lett
, vol.84
, pp. 57-62
-
-
Ishida, M.1
Iwai, Y.2
Tanaka, Y.3
Okazaki, T.4
Freeman, G.J.5
Minato, N.6
Honjo, T.7
-
7
-
-
55849116389
-
CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope
-
Skowera A, Ellis RJ, Varela-Calviño R, Arif S, Huang GC, Van-Krinks C, Zaremba A, Rackham C, Allen JS, Tree TI, Zhao M, Dayan CM, Sewell AK, Unger WW, Unger W, Drijfhout JW, Ossendorp F, Roep BO, Peakman M. CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope. J Clin Invest 2008;118:3390-3402
-
(2008)
J Clin Invest
, vol.118
, pp. 3390-3402
-
-
Skowera, A.1
Ellis, R.J.2
Varela-Calviño, R.3
Arif, S.4
Huang, G.C.5
Van-Krinks, C.6
Zaremba, A.7
Rackham, C.8
Allen, J.S.9
Tree, T.I.10
Zhao, M.11
Dayan, C.M.12
Sewell, A.K.13
Unger, W.W.14
Unger, W.15
Drijfhout, J.W.16
Ossendorp, F.17
Roep, B.O.18
Peakman, M.19
-
8
-
-
44049086242
-
Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice
-
Mukhopadhaya A, Hanafusa T, Jarchum I, Chen YG, Iwai Y, Serreze DV, Steinman RM, Tarbell KV, DiLorenzo TP. Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice. Proc Natl Acad Sci U S A 2008;105:6374-6379
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 6374-6379
-
-
Mukhopadhaya, A.1
Hanafusa, T.2
Jarchum, I.3
Chen, Y.G.4
Iwai, Y.5
Serreze, D.V.6
Steinman, R.M.7
Tarbell, K.V.8
DiLorenzo, T.P.9
-
9
-
-
3142694831
-
Expression of the B7.1 costimulatory molecule on pancreatic beta cells abrogates the requirement for CD4 T cells in the development of type 1 diabetes
-
Havari E, Lennon-Dumenil AM, Klein L, Neely D, Taylor JA, McInerney MF, Wucherpfennig KW, Lipes MA. Expression of the B7.1 costimulatory molecule on pancreatic beta cells abrogates the requirement for CD4 T cells in the development of type 1 diabetes. J Immunol 2004;173:787-796
-
(2004)
J Immunol
, vol.173
, pp. 787-796
-
-
Havari, E.1
Lennon-Dumenil, A.M.2
Klein, L.3
Neely, D.4
Taylor, J.A.5
McInerney, M.F.6
Wucherpfennig, K.W.7
Lipes, M.A.8
-
10
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, Nishimura H, Fitz LJ, Malenkovich N, Okazaki T, Byrne MC, Horton HF, Fouser L, Carter L, Ling V, Bowman MR, Carreno BM, Collins M, Wood CR, Honjo T. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000;192:1027-1034
-
(2000)
J Exp Med
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
Fitz, L.J.7
Malenkovich, N.8
Okazaki, T.9
Byrne, M.C.10
Horton, H.F.11
Fouser, L.12
Carter, L.13
Ling, V.14
Bowman, M.R.15
Carreno, B.M.16
Collins, M.17
Wood, C.R.18
Honjo, T.19
-
11
-
-
0037477605
-
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice
-
Ansari MJ, Salama AD, Chitnis T, Smith RN, Yagita H, Akiba H, Yamazaki T, Azuma M, Iwai H, Khoury SJ, Auchincloss H, Jr, Sayegh MH. The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med 2003;198:63-69
-
(2003)
J Exp Med
, vol.198
, pp. 63-69
-
-
Ansari, M.J.1
Salama, A.D.2
Chitnis, T.3
Smith, R.N.4
Yagita, H.5
Akiba, H.6
Yamazaki, T.7
Azuma, M.8
Iwai, H.9
Khoury, S.J.10
Auchincloss Jr., H.11
Sayegh, M.H.12
-
12
-
-
0034927194
-
PD-1: An inhibitory immunoreceptor involved in peripheral tolerance
-
Nishimura H, Honjo T. PD-1: an inhibitory immunoreceptor involved in peripheral tolerance. Trends Immunol 2001;22:265-268
-
(2001)
Trends Immunol
, vol.22
, pp. 265-268
-
-
Nishimura, H.1
Honjo, T.2
-
13
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, Iwai Y, Long AJ, Brown JA, Nunes R, Greenfield EA, Bourque K, Boussiotis VA, Carter LL, Carreno BM, Malenkovich N, Nishimura H, Okazaki T, Honjo T, Sharpe AH, Freeman GJ. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol 2001;2:261-268
-
(2001)
Nat Immunol
, vol.2
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
Chaudhary, D.4
Borde, M.5
Chernova, I.6
Iwai, Y.7
Long, A.J.8
Brown, J.A.9
Nunes, R.10
Greenfield, E.A.11
Bourque, K.12
Boussiotis, V.A.13
Carter, L.L.14
Carreno, B.M.15
Malenkovich, N.16
Nishimura, H.17
Okazaki, T.18
Honjo, T.19
Sharpe, A.H.20
Freeman, G.J.21
more..
-
14
-
-
0141433189
-
Stimulating PD-1-negative signals concurrent with blocking CD154 co-stimulation induces long-term islet allograft survival
-
Gao W, Demirci G, Strom TB, Li XC. Stimulating PD-1-negative signals concurrent with blocking CD154 co-stimulation induces long-term islet allograft survival. Transplantation 2003;76:994-999
-
(2003)
Transplantation
, vol.76
, pp. 994-999
-
-
Gao, W.1
Demirci, G.2
Strom, T.B.3
Li, X.C.4
-
15
-
-
77955359941
-
Deficiency in B7-H1 (PD-L1)/PD-1 coinhibition triggers pancreatic β-cell destruction by insulin-specific, murine CD8 T-cells
-
Rajasalu T, Brosi H, Schuster C, Spyrantis A, Boehm BO, Chen L, Reimann J, Schirmbeck R. Deficiency in B7-H1 (PD-L1)/PD-1 coinhibition triggers pancreatic β-cell destruction by insulin-specific, murine CD8 T-cells. Diabetes 2010;59:1966-1973
-
(2010)
Diabetes
, vol.59
, pp. 1966-1973
-
-
Rajasalu, T.1
Brosi, H.2
Schuster, C.3
Spyrantis, A.4
Boehm, B.O.5
Chen, L.6
Reimann, J.7
Schirmbeck, R.8
-
16
-
-
34547905736
-
The diabetogenic, insulin-specific CD8 T cell response primed in the experimental autoimmune diabetes model in RIP-B7.1 mice
-
Karges W, Rajasalu T, Spyrantis A, Wieland A, Boehm B, Schirmbeck R. The diabetogenic, insulin-specific CD8 T cell response primed in the experimental autoimmune diabetes model in RIP-B7.1 mice. Eur J Immunol 2007;37:2097-2103
-
(2007)
Eur J Immunol
, vol.37
, pp. 2097-2103
-
-
Karges, W.1
Rajasalu, T.2
Spyrantis, A.3
Wieland, A.4
Boehm, B.5
Schirmbeck, R.6
-
17
-
-
70349745490
-
T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event
-
Lennon GP, Bettini M, Burton AR, Vincent E, Arnold PY, Santamaria P, Vignali DA. T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event. Immunity 2009;31:643-653
-
(2009)
Immunity
, vol.31
, pp. 643-653
-
-
Lennon, G.P.1
Bettini, M.2
Burton, A.R.3
Vincent, E.4
Arnold, P.Y.5
Santamaria, P.6
Vignali, D.A.7
-
18
-
-
77954155091
-
Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to beta cell damage
-
Alam MU, Harken JA, Knorn AM, Elford AR, Wigmore K, Ohashi PS, Millar DG. Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to beta cell damage. J Immunol 2009;183:5728-5737
-
(2009)
J Immunol
, vol.183
, pp. 5728-5737
-
-
Alam, M.U.1
Harken, J.A.2
Knorn, A.M.3
Elford, A.R.4
Wigmore, K.5
Ohashi, P.S.6
Millar, D.G.7
|