A p120-catenin-CK1ε complex regulates Wnt signaling

Journal of Cell Science

Volumn 123, Issue 15, 2010, Pages 2621-2631

  Casagolda, David ^a   Del Valle Pérez, Beatriz ^a   Valls, Gabriela ^a   Lugilde, Ero ^a   Vinyoles, Meritxell ^a   Casado Vela, Juan ^b,h   Solanas, Guiomar ^c   Batlle, Eduard ^c   Reynolds, Albert B ^d   Casal, José Ignacio ^b,e   García De Herreros, Antonio ^f,g   Duñach, Mireia ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b Centro Nacional de Investigaciones Oncológicas   (Spain)

^c INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^f HOSPITAL DEL MAR   (Spain)

^g UNIVERSITAT POMPEU FABRA   (Spain)

^h CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

CK1 ; E cadherin; p120 catenin; Wnt

Indexed keywords

AXIN; BETA CATENIN; CASEIN KINASE IEPSILON; CATENIN; DISHEVELLED 2; FRIZZLED PROTEIN; LIPOPROTEIN RECEPTOR; P120 CATENIN; UNCLASSIFIED DRUG; UVOMORULIN; WNT PROTEIN; WNT3A PROTEIN; CADHERIN; DELTA CATENIN; DISHEVELLED PROTEINS; LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LRP6 PROTEIN, HUMAN; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; GENE ACTIVATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; DRUG EFFECT; GENETICS; IMMUNOPRECIPITATION; MASS SPECTROMETRY; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CADHERINS; CASEIN KINASE IEPSILON; CATENINS; CELL LINE, TUMOR; HUMANS; IMMUNOPRECIPITATION; LDL-RECEPTOR RELATED PROTEINS; MASS SPECTROMETRY; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 77955350405     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.067512     Document Type: Article

References (39)

1. Alemà, S. and Salvatore, A. M. (2007). p120-catenin and phosphorylation: mechanisms and traits of an unresolved issue. Biochim. Biophys. Acta 1773, 47-58.
2. Anastasiadis, P. Z. (2007). p120-catenin: a nexus for contextual signaling via Rho GTPases. Biochim. Biophys. Acta 1773, 34-46.
3. Bilic, J., Huang, Y. L., Davidson, G., Zimmerman, T., Cruciat, C. M., Bienz, M. and Niehrs, C. (2007). Wnt induces LRP5/6 signalosomes and promote dishevelled-dependent LRP5/6 phosphorylation. Science 316, 1619-1622.
4. Casado-Vela, J., Ruiz, E. J., Nebreda, A. R. and Casal, J. I. (2007). A combination of neutral loss and selected ion monitoring with two enzymatic digestions enables a comprehensive mapping of phosphorylation sites. Proteomics 7, 2522-2529. (Pubitemid 47253812)
5. Castaño, J., Solanas, G., Casagolda, D., Raurell, I., Villagrasa, P., Bustelo, X. R., Garcia de Herreros, A. and Duñach, M. (2007). Specific phosphorylation of p120-catenin regulatory domain differently modulates its binding to RhoA. Mol. Cell. Biol. 27, 1745-1757.
6. Conacci-Sorrell, M., Simcha, I., Ben-Yedidia, T., Blechman, J., Savagner, P. and Ben-Ze'ev, A. (2003). Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK. J. Cell Biol. 163, 847-857.
7. Dahlberg, C. L., Nguyen, E. Z., Goodlett, D. and Kimmelman, D. (2009). Interactions between casein kinase Iε (CK1ε) and two substrates from disparate signaling pathways reveal mechanism fro substrate-kinase specificity. PLoS ONE 4, 44766.
8. Daniel, J. M. and Reynolds, A. B. (1999). The catenin p120(ctn) interacts with kaiso, a novel BTB/POZ domain zinc finger transcription factor. Mol. Cell. Biol. 19, 3614-3623. (Pubitemid 29193821)
9. Davidson, G., Wu, W., Shen, J., Bilic, J., Fenger, U., Stannek, P., Glinka, A. and Niehrs, C. (2005). Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction. Nature 438, 867-892.
10. Davis, M. A., Ireton, R. C. and Reynolds, A. B. (2003). A core function for p120-catenin in cadherin turnover. J. Cell Biol. 163, 525-534.
11. Dupre-Cochet, S., Figueroa, A., Hogan, C., Ferber, E., Bialucha, C. U., Adams, J., Richardson, E. and Fujita, Y. (2007). Casein kinase 1 is a novel negative regulator of E-cadherin-based cell-cell contacts. Mol. Cell. Biol. 27, 3804-3816.
12. Gao, Z. H., Seeling, J. M., Hill, V., Yochum, A. and Virshup, D. M. (2002). Casein kinase I phosphorylates and destabilizes the b-catenin degradation complex. Proc. Natl. Acad. Sci. USA 99, 1182-1187. (Pubitemid 34136467)
13. Hay, E., Laplantine, E., Geoffroy, G., Frain, M., Kohler, T., Müller, T. and Marie, P. J. (2009). N-cadherin interacts with Axin and LRP5 to negatively regulate Wnt/β-catenin signaling, osteoblast function and bone formation. Mol. Cell. Biol. 29, 953-964.
14. He, T. C., Sparks, A. B., Rago, C., Hermeking, H., Zawel, L., da Costa, L. T., Morin, P. J., Vogelstein, B. and Kinzler, K. W. (1998). Identification of c-MYC as a target of the APC pathway. Science 281, 1509-1512.
15. He, X., Semenov, M., Tamai, K. and Zeng, X. (2004). LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development 131, 1663-1677.
16. Hino, S., Michiue, T., Asashima, M. and Kikuchi, A. (2003). Casein kinase 1ε enhances binding of Dvl-1 to Frat-1 and is essential fro Wnt3a-induced accumulation of β-catenin. J. Biol. Chem. 278, 14066-14073. (Pubitemid 36799952)
17. Ireton, R., Davis, M., van Hengel, J., Mariner, D., Barnes, K., Thoreson, M., Anastasiadis, P., Matrisian, L., Bundy, L., Sealy, B. et al. (2002). A novel role for p120-catenin in E-cadherin function. J. Cell Biol. 159, 465-476.
18. Kim, L. and Wong, T. W. (1995). The cytoplasmic tyrosine kinase Fer is associated with the catenin substrate pp120 and is activated by growth factors. Mol. Cell. Biol. 15, 4553-4561.
19. Knippschild, U., Gocht, A., Wolff, S., Huber, N., Lohler, J. and Stoter, M. (2005). The casein kinase 1 family: participation in multiple cellular processes in eukaryotes. Cell Signal. 17, 675-689. (Pubitemid 40250168)
20. Liu, C., Li, Y., Semenov, M., Han, C., Baeg, G. H., Tan, Y., Zhang, Z., Lin, X. and He, X. (2002). Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 108, 837-847.
21. MacDonald, B., Tamai, K. and He, X. (2009). Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev. Cell 17, 9-26.
22. Mao, J., Wang, J., Liu, B., Pan, W., Farr, G. H., Flynn, C., Yuan, H., Takada, S., Kimelman, D., Li, L. et al. (2001). Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol. Cell 7, 801-809.
23. Mashoon, N., DeMaggio, D. J., Tereshko, V., Bergmeier, S. C., Egli, M., Hoekstra, M. F. and Kuret, J. (2000). Crystal structure of a conformation-selective casein kinase-1 inhibitor. J. Biol. Chem. 275, 20052-20060. (Pubitemid 30441614)
24. Park, J. I., Kim, S. W., Lyons, J. P., Ji, H., Nguyen, T. T., Cho, K., Barton, M. C., Deroo, T., Vleminckx, K., Moon, R. T. et al. (2006). Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets. Dev. Cell 8, 843-854.
25. Peters, J. M., MacKay, R. M., MacKay, J. P. and Graff, J. M. (1999). Casein kinase I transduces Wnt signals. Nature 401, 345-350.
26. Piao, S., Lee, S. H., Kim, H., Yum, S., Stamos, J. L., Xu, Y., Lee, S. J., Lee, J., Oh, S., Han, J. K. et al. (2008). Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling. PLoS ONE 3, e4046.
27. Price, M. A. (2006). CK1, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling. Genes Dev. 20, 399-410.
28. Raurell, I., Codina, M., Casagolda, D., Del Valle, B., Baulida, J., García de Herreros, A. and Duñach, M. (2008). Gamma-secretase- dependent and -independent effects of presenilin1 on β-catenin•Tcf-4 transcriptional activity. PLoS ONE 3, e4080.
29. Reya, T. and Clevers, H. (2005). Wnt signaling in stem cells and cancer. Nature 434, 843-850. (Pubitemid 40558990)
30. Sakanaka, C., Leong, P., Xu, L., Harrison, S. D. and Williams, L. T. (1999). Casein kinase 1ε in the wnt pathway: regulation of β-catenin function. Proc. Natl. Acad. Sci. USA 96, 12548-12552.
31. Solanas, G., Porta-de-la-Riva, M., Agustí, C., Casagolda, D., Sánchez-Aguilera, F., Larriba, M. J., Pons, F., Peiró, S., Escrivà, M., Muñoz, A. et al. (2008). E-cadherin controls beta-catenin and NF-kappaB transcriptional activity in mesenchymal gene expression. J. Cell Sci. 121, 2224-2234.
32. Swiatek, W., Tsai, I. C., Klimowski, L., Pepler, A., Barnette, J., Yost, H. J. and Virshup, D. M. (2004). Regulation of casein kinase 1ε activity by Wnt. J. Biol. Chem. 279, 13011-13017.
33. Van de Wetering, M., Sancho, E., Verweij, C., de Lau, W., Oving, I., Hurlstone, A., van der Horn, K., Batlle, E., Coudreuse, D., Haramis, A. P. et al. (2002). The betacatenin/ TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 111, 241-250.
34. Wu, G., Huang, H., Garcia Abreu, J. and He, X. (2009). Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6. PLoS ONE 4, e4926.
35. Xia, X., Brooks, J., Campos-González, R. and Reynolds, A. B. (2004). Serine and threonine phospho-specific antibodies to p120-catenin. Hybrid. Hybridomics 23, 343-351. (Pubitemid 39658506)
36. Xu, X., Tu, X., Joeng, S., Hilton, M. J., Williams, D. A. and Long, F. (2008). Rac1 activation controls nuclear localization of β-catenin during canonical Wnt signalling. Cell 133, 340-353.
37. Yanigisawa, M., Huveldt, D., Kreinest, P., Lohse, C. M., Cheville, J. C., Parker, A. S., Copland, J. A. and Anastasiadis, P. (2008). A p120-catenin isoform switch affects Rho activity, induces tumor cell invasion and predicts metastasis disease. J. Biol. Chem. 283, 18344-18354.
38. Zeng, X., Tamai, K., Doble, B., Li, S., Huang, H., Habas, R., Okamura, H., Woodgett, J. and He, X. (2005). A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature 438, 873-877.
39. Zeng, X., Huang, H., Tamai, K., Zhang, X., Harada, Y., Yokota, C., Almeida, K., Wang, J., Doble, B., Woodgett, J. et al. (2008). Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development 135, 367-375.