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Volumn 31, Issue 8, 2010, Pages 303-310

Early T cell development and the pitfalls of potential

Author keywords

[No Author keywords available]

Indexed keywords

BONE MARROW CELL; HEMATOPOIESIS; HUMAN; LYMPHOCYTE DIFFERENTIATION; LYMPHOID CELL; NONHUMAN; PRE T LYMPHOCYTE; REVIEW; T LYMPHOCYTE; ANIMAL; BONE MARROW; CELL LINEAGE; CYTOLOGY; IMMUNOLOGY; METABOLISM; THYMUS;

EID: 77955275648     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2010.06.002     Document Type: Review
Times cited : (46)

References (97)
  • 1
    • 39349096526 scopus 로고    scopus 로고
    • Hematopoiesis: an evolving paradigm for stem cell biology
    • Orkin S.H., Zon L.I. Hematopoiesis: an evolving paradigm for stem cell biology. Cell 2008, 132:631-644.
    • (2008) Cell , vol.132 , pp. 631-644
    • Orkin, S.H.1    Zon, L.I.2
  • 2
    • 51149097393 scopus 로고    scopus 로고
    • Space-time considerations for hematopoietic stem cell transplantation
    • Bhattacharya D., et al. Space-time considerations for hematopoietic stem cell transplantation. Eur. J. Immunol. 2008, 38:2060-2067.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 2060-2067
    • Bhattacharya, D.1
  • 3
    • 17444408151 scopus 로고    scopus 로고
    • The complex cartography of stem cell commitment
    • Akashi K., et al. The complex cartography of stem cell commitment. Cell 2005, 121:160-162.
    • (2005) Cell , vol.121 , pp. 160-162
    • Akashi, K.1
  • 4
    • 63149172079 scopus 로고    scopus 로고
    • Models of haematopoiesis: seeing the wood for the trees
    • Ceredig R., et al. Models of haematopoiesis: seeing the wood for the trees. Nat. Rev. Immunol. 2009, 9:293-300.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 293-300
    • Ceredig, R.1
  • 5
    • 0030831130 scopus 로고    scopus 로고
    • Identification of clonogenic common lymphoid progenitors in mouse bone marrow
    • Kondo M., et al. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997, 91:661-672.
    • (1997) Cell , vol.91 , pp. 661-672
    • Kondo, M.1
  • 6
    • 0034624828 scopus 로고    scopus 로고
    • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    • Akashi K., et al. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 2000, 404:193-197.
    • (2000) Nature , vol.404 , pp. 193-197
    • Akashi, K.1
  • 7
    • 42049122615 scopus 로고    scopus 로고
    • Immunology: blood lines redrawn
    • Graf T. Immunology: blood lines redrawn. Nature 2008, 452:702-703.
    • (2008) Nature , vol.452 , pp. 702-703
    • Graf, T.1
  • 8
    • 65449161461 scopus 로고    scopus 로고
    • A new paradigm for hematopoietic cell lineages: revision of the classical concept of the myeloid-lymphoid dichotomy
    • Kawamoto H., Katsura Y. A new paradigm for hematopoietic cell lineages: revision of the classical concept of the myeloid-lymphoid dichotomy. Trends Immunol. 2009, 30:193-200.
    • (2009) Trends Immunol. , vol.30 , pp. 193-200
    • Kawamoto, H.1    Katsura, Y.2
  • 9
    • 65249096624 scopus 로고    scopus 로고
    • Untangling the T branch of the hematopoiesis tree
    • Chi A.W., et al. Untangling the T branch of the hematopoiesis tree. Curr. Opin. Immunol. 2009, 21:121-126.
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 121-126
    • Chi, A.W.1
  • 10
    • 42049087865 scopus 로고    scopus 로고
    • The earliest thymic progenitors for T cells possess myeloid lineage potential
    • Bell J.J., Bhandoola A. The earliest thymic progenitors for T cells possess myeloid lineage potential. Nature 2008, 452:764-767.
    • (2008) Nature , vol.452 , pp. 764-767
    • Bell, J.J.1    Bhandoola, A.2
  • 11
    • 42049089318 scopus 로고    scopus 로고
    • Adult T cell progenitors retain myeloid potential
    • Wada H., et al. Adult T cell progenitors retain myeloid potential. Nature 2008, 452:768-772.
    • (2008) Nature , vol.452 , pp. 768-772
    • Wada, H.1
  • 12
    • 22344450253 scopus 로고    scopus 로고
    • A multipotent precursor in the thymus maps to the branching point of the T versus B lineage decision
    • Benz C., Bleul C.C. A multipotent precursor in the thymus maps to the branching point of the T versus B lineage decision. J. Exp. Med. 2005, 202:21-31.
    • (2005) J. Exp. Med. , vol.202 , pp. 21-31
    • Benz, C.1    Bleul, C.C.2
  • 13
    • 33747781772 scopus 로고    scopus 로고
    • Primitive lymphoid progenitors in bone marrow with T lineage reconstituting potential
    • Perry S.S., et al. Primitive lymphoid progenitors in bone marrow with T lineage reconstituting potential. J. Immunol. 2006, 177:2880-2887.
    • (2006) J. Immunol. , vol.177 , pp. 2880-2887
    • Perry, S.S.1
  • 14
    • 34250159205 scopus 로고    scopus 로고
    • Identification of a bone marrow precursor of the earliest thymocytes in adult mouse
    • Lai A.Y., Kondo M. Identification of a bone marrow precursor of the earliest thymocytes in adult mouse. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:6311-6316.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 6311-6316
    • Lai, A.Y.1    Kondo, M.2
  • 15
    • 0036669273 scopus 로고    scopus 로고
    • Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow
    • Igarashi H., et al. Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow. Immunity 2002, 17:117-130.
    • (2002) Immunity , vol.17 , pp. 117-130
    • Igarashi, H.1
  • 16
    • 0042383366 scopus 로고    scopus 로고
    • Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential
    • Martin C.H., et al. Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential. Nat. Immunol. 2003, 4:866-873.
    • (2003) Nat. Immunol. , vol.4 , pp. 866-873
    • Martin, C.H.1
  • 17
    • 22544451234 scopus 로고    scopus 로고
    • A B220+ CD117+ CD19- hematopoietic progenitor with potent lymphoid and myeloid developmental potential
    • Balciunaite G., et al. A B220+ CD117+ CD19- hematopoietic progenitor with potent lymphoid and myeloid developmental potential. Eur. J. Immunol. 2005, 35:2019-2030.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 2019-2030
    • Balciunaite, G.1
  • 18
    • 14944355917 scopus 로고    scopus 로고
    • Prospective isolation and global gene expression analysis of the erythrocyte colony-forming unit (CFU-E)
    • Terszowski G., et al. Prospective isolation and global gene expression analysis of the erythrocyte colony-forming unit (CFU-E). Blood 2005, 105:1937-1945.
    • (2005) Blood , vol.105 , pp. 1937-1945
    • Terszowski, G.1
  • 19
    • 0036916440 scopus 로고    scopus 로고
    • Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro
    • Schmitt T.M., Zuniga-Pflucker J.C. Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity 2002, 17:749-756.
    • (2002) Immunity , vol.17 , pp. 749-756
    • Schmitt, T.M.1    Zuniga-Pflucker, J.C.2
  • 20
    • 0035476891 scopus 로고    scopus 로고
    • Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation
    • Jaleco A.C., et al. Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation. J. Exp. Med. 2001, 194:991-1002.
    • (2001) J. Exp. Med. , vol.194 , pp. 991-1002
    • Jaleco, A.C.1
  • 21
    • 2942659675 scopus 로고    scopus 로고
    • Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo
    • Hozumi K., et al. Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo. Nat. Immunol. 2004, 5:638-644.
    • (2004) Nat. Immunol. , vol.5 , pp. 638-644
    • Hozumi, K.1
  • 22
    • 0029320262 scopus 로고
    • In-vitro analyses of mechanisms of B cell development
    • Rolink A., et al. In-vitro analyses of mechanisms of B cell development. Semin. Immunol. 1995, 7:155-167.
    • (1995) Semin. Immunol. , vol.7 , pp. 155-167
    • Rolink, A.1
  • 23
    • 77949956058 scopus 로고    scopus 로고
    • Fate mapping reveals separate origins of T cells and myeloid lineages in the thymus
    • Schlenner S.M., et al. Fate mapping reveals separate origins of T cells and myeloid lineages in the thymus. Immunity 2010, 32:426-436.
    • (2010) Immunity , vol.32 , pp. 426-436
    • Schlenner, S.M.1
  • 24
    • 34249707006 scopus 로고    scopus 로고
    • Molecular dissection of prethymic progenitor entry into the T lymphocyte developmental pathway
    • Tydell C.C., et al. Molecular dissection of prethymic progenitor entry into the T lymphocyte developmental pathway. J. Immunol. 2007, 179:421-438.
    • (2007) J. Immunol. , vol.179 , pp. 421-438
    • Tydell, C.C.1
  • 26
    • 41949098160 scopus 로고    scopus 로고
    • Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency
    • Hanna J., et al. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell 2008, 133:250-264.
    • (2008) Cell , vol.133 , pp. 250-264
    • Hanna, J.1
  • 27
    • 0029022214 scopus 로고
    • Pathways from hematopoietic stem cells to thymocytes
    • Rodewald H.R. Pathways from hematopoietic stem cells to thymocytes. Curr. Opin. Immunol. 1995, 7:176-187.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 176-187
    • Rodewald, H.R.1
  • 28
    • 22344452256 scopus 로고    scopus 로고
    • Many roads, one destination for T cell progenitors
    • Petrie H.T., Kincade P.W. Many roads, one destination for T cell progenitors. J. Exp. Med. 2005, 202:11-13.
    • (2005) J. Exp. Med. , vol.202 , pp. 11-13
    • Petrie, H.T.1    Kincade, P.W.2
  • 29
    • 33644842282 scopus 로고    scopus 로고
    • From stem cell to T cell: one route or many?
    • Bhandoola A., Sambandam A. From stem cell to T cell: one route or many?. Nat. Rev. Immunol. 2006, 6:117-126.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 117-126
    • Bhandoola, A.1    Sambandam, A.2
  • 30
    • 34250212481 scopus 로고    scopus 로고
    • Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from
    • Bhandoola A., et al. Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from. Immunity 2007, 26:678-689.
    • (2007) Immunity , vol.26 , pp. 678-689
    • Bhandoola, A.1
  • 31
    • 33644661207 scopus 로고    scopus 로고
    • T lineage progenitors: the earliest steps en route to T lymphocytes
    • Wu L. T lineage progenitors: the earliest steps en route to T lymphocytes. Curr. Opin. Immunol. 2006, 18:121-126.
    • (2006) Curr. Opin. Immunol. , vol.18 , pp. 121-126
    • Wu, L.1
  • 32
    • 0036831290 scopus 로고    scopus 로고
    • A positive look at double-negative thymocytes
    • Ceredig R., Rolink T. A positive look at double-negative thymocytes. Nat. Rev. Immunol. 2002, 2:888-897.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 888-897
    • Ceredig, R.1    Rolink, T.2
  • 33
    • 0036485175 scopus 로고    scopus 로고
    • Redefinition of lymphoid progenitors
    • Katsura Y. Redefinition of lymphoid progenitors. Nat. Rev. Immunol. 2002, 2:127-132.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 127-132
    • Katsura, Y.1
  • 34
    • 33745574980 scopus 로고    scopus 로고
    • The thymus and T cell commitment: the right niche for Notch?
    • Jenkinson E.J., et al. The thymus and T cell commitment: the right niche for Notch?. Nat. Rev. Immunol. 2006, 6:551-555.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 551-555
    • Jenkinson, E.J.1
  • 35
    • 33748448909 scopus 로고    scopus 로고
    • Thymus-homing precursors and the thymic microenvironment
    • Boehm T., Bleul C.C. Thymus-homing precursors and the thymic microenvironment. Trends Immunol. 2006, 27:477-484.
    • (2006) Trends Immunol. , vol.27 , pp. 477-484
    • Boehm, T.1    Bleul, C.C.2
  • 37
    • 0034749999 scopus 로고    scopus 로고
    • Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity
    • Adolfsson J., et al. Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity. Immunity 2001, 15:659-669.
    • (2001) Immunity , vol.15 , pp. 659-669
    • Adolfsson, J.1
  • 38
    • 33746208874 scopus 로고    scopus 로고
    • New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors
    • Forsberg E.C., et al. New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. Cell 2006, 126:415-426.
    • (2006) Cell , vol.126 , pp. 415-426
    • Forsberg, E.C.1
  • 39
    • 1842474899 scopus 로고    scopus 로고
    • L-selectin defines a bone marrow analog to the thymic early T-lineage progenitor
    • Perry S.S., et al. L-selectin defines a bone marrow analog to the thymic early T-lineage progenitor. Blood 2004, 103:2990-2996.
    • (2004) Blood , vol.103 , pp. 2990-2996
    • Perry, S.S.1
  • 40
    • 47049088149 scopus 로고    scopus 로고
    • Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages
    • Karsunky H., et al. Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages. Blood 2008, 111:5562-5570.
    • (2008) Blood , vol.111 , pp. 5562-5570
    • Karsunky, H.1
  • 41
    • 0037320932 scopus 로고    scopus 로고
    • Thymopoiesis independent of common lymphoid progenitors
    • Allman D., et al. Thymopoiesis independent of common lymphoid progenitors. Nat. Immunol. 2003, 4:168-174.
    • (2003) Nat. Immunol. , vol.4 , pp. 168-174
    • Allman, D.1
  • 42
    • 59649094661 scopus 로고    scopus 로고
    • Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis
    • Serwold T., et al. Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis. Blood 2009, 113:807-815.
    • (2009) Blood , vol.113 , pp. 807-815
    • Serwold, T.1
  • 43
    • 33645081733 scopus 로고    scopus 로고
    • Lineage specification and plasticity in CD19- early B cell precursors
    • Rumfelt L.L., et al. Lineage specification and plasticity in CD19- early B cell precursors. J. Exp. Med. 2006, 203:675-687.
    • (2006) J. Exp. Med. , vol.203 , pp. 675-687
    • Rumfelt, L.L.1
  • 44
    • 0028122624 scopus 로고
    • Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization
    • Rodewald H.R., et al. Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization. EMBO J. 1994, 13:4229-4240.
    • (1994) EMBO J. , vol.13 , pp. 4229-4240
    • Rodewald, H.R.1
  • 45
    • 33947698011 scopus 로고    scopus 로고
    • The blood contains multiple distinct progenitor populations with clonogenic B and T lineage potential
    • Umland O., et al. The blood contains multiple distinct progenitor populations with clonogenic B and T lineage potential. J. Immunol. 2007, 178:4147-4152.
    • (2007) J. Immunol. , vol.178 , pp. 4147-4152
    • Umland, O.1
  • 46
    • 4644329449 scopus 로고    scopus 로고
    • Circulating hematopoietic progenitors with T lineage potential
    • Schwarz B.A., Bhandoola A. Circulating hematopoietic progenitors with T lineage potential. Nat. Immunol. 2004, 5:953-960.
    • (2004) Nat. Immunol. , vol.5 , pp. 953-960
    • Schwarz, B.A.1    Bhandoola, A.2
  • 47
    • 33846240496 scopus 로고    scopus 로고
    • Identification of a T lineage-committed progenitor in adult blood
    • Krueger A., von Boehmer S H. Identification of a T lineage-committed progenitor in adult blood. Immunity 2007, 26:105-116.
    • (2007) Immunity , vol.26 , pp. 105-116
    • Krueger, A.1    von Boehmer S, H.2
  • 48
    • 33646480885 scopus 로고    scopus 로고
    • A multistep adhesion cascade for lymphoid progenitor cell homing to the thymus
    • Scimone M.L., et al. A multistep adhesion cascade for lymphoid progenitor cell homing to the thymus. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:7006-7011.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 7006-7011
    • Scimone, M.L.1
  • 49
    • 2942516896 scopus 로고    scopus 로고
    • Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages
    • Porritt H.E., et al. Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages. Immunity 2004, 20:735-745.
    • (2004) Immunity , vol.20 , pp. 735-745
    • Porritt, H.E.1
  • 50
    • 22144487402 scopus 로고    scopus 로고
    • Notch signaling controls the generation and differentiation of early T lineage progenitors
    • Sambandam A., et al. Notch signaling controls the generation and differentiation of early T lineage progenitors. Nat. Immunol. 2005, 6:663-670.
    • (2005) Nat. Immunol. , vol.6 , pp. 663-670
    • Sambandam, A.1
  • 51
    • 0028804041 scopus 로고
    • Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo
    • Rodewald H.R., et al. Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo. Immunity 1995, 3:313-319.
    • (1995) Immunity , vol.3 , pp. 313-319
    • Rodewald, H.R.1
  • 52
    • 74249114655 scopus 로고    scopus 로고
    • Flt3 ligand-receptor interaction is important for maintenance of early thymic progenitor numbers in steady-state thymopoiesis
    • Kenins L., et al. Flt3 ligand-receptor interaction is important for maintenance of early thymic progenitor numbers in steady-state thymopoiesis. Eur. J. Immunol. 2010, 40:81-90.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 81-90
    • Kenins, L.1
  • 53
    • 0031956471 scopus 로고    scopus 로고
    • In vivo roles of receptor tyrosine kinases and cytokine receptors in early thymocyte development
    • Di Santo J.P., Rodewald H.R. In vivo roles of receptor tyrosine kinases and cytokine receptors in early thymocyte development. Curr. Opin. Immunol. 1998, 10:196-207.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 196-207
    • Di Santo, J.P.1    Rodewald, H.R.2
  • 54
    • 58149251919 scopus 로고    scopus 로고
    • Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms
    • Feyerabend T.B., et al. Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms. Immunity 2009, 30:67-79.
    • (2009) Immunity , vol.30 , pp. 67-79
    • Feyerabend, T.B.1
  • 55
    • 74549176827 scopus 로고    scopus 로고
    • Notch signaling in the immune system
    • Radtke F., et al. Notch signaling in the immune system. Immunity 2010, 32:14-27.
    • (2010) Immunity , vol.32 , pp. 14-27
    • Radtke, F.1
  • 56
    • 58149216772 scopus 로고    scopus 로고
    • Notch 1 keeps pro-T cells on track
    • von Boehmer H. Notch 1 keeps pro-T cells on track. Immunity 2009, 30:5-7.
    • (2009) Immunity , vol.30 , pp. 5-7
    • von Boehmer, H.1
  • 57
    • 58149151302 scopus 로고    scopus 로고
    • Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment
    • Koch U., et al. Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. J. Exp. Med. 2008, 205:2515-2523.
    • (2008) J. Exp. Med. , vol.205 , pp. 2515-2523
    • Koch, U.1
  • 58
    • 58149154746 scopus 로고    scopus 로고
    • Delta-like 4 is indispensable in thymic environment specific for T cell development
    • Hozumi K., et al. Delta-like 4 is indispensable in thymic environment specific for T cell development. J. Exp. Med. 2008, 205:2507-2513.
    • (2008) J. Exp. Med. , vol.205 , pp. 2507-2513
    • Hozumi, K.1
  • 59
    • 42649138855 scopus 로고    scopus 로고
    • Thymus organogenesis
    • Rodewald H.R. Thymus organogenesis. Annu. Rev. Immunol. 2008, 26:355-388.
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 355-388
    • Rodewald, H.R.1
  • 60
    • 33847103659 scopus 로고    scopus 로고
    • Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation
    • Besseyrias V., et al. Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation. J. Exp. Med. 2007, 204:331-343.
    • (2007) J. Exp. Med. , vol.204 , pp. 331-343
    • Besseyrias, V.1
  • 61
    • 37549010335 scopus 로고    scopus 로고
    • Launching the T cell-lineage developmental programme
    • Rothenberg E.V., et al. Launching the T cell-lineage developmental programme. Nat. Rev. Immunol. 2008, 8:9-21.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 9-21
    • Rothenberg, E.V.1
  • 62
    • 0026561448 scopus 로고
    • Bipotential precursors of B cells and macrophages in murine fetal liver
    • Cumano A., et al. Bipotential precursors of B cells and macrophages in murine fetal liver. Nature 1992, 356:612-615.
    • (1992) Nature , vol.356 , pp. 612-615
    • Cumano, A.1
  • 63
    • 76249131631 scopus 로고    scopus 로고
    • Asynchronous RAG-1 expression during B lymphopoiesis
    • Welner R.S., et al. Asynchronous RAG-1 expression during B lymphopoiesis. J. Immunol. 2009, 183:7768-7777.
    • (2009) J. Immunol. , vol.183 , pp. 7768-7777
    • Welner, R.S.1
  • 64
    • 0027205082 scopus 로고
    • Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population
    • Ardavin C., et al. Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population. Nature 1993, 362:761-763.
    • (1993) Nature , vol.362 , pp. 761-763
    • Ardavin, C.1
  • 65
    • 0031726323 scopus 로고    scopus 로고
    • The linkage between T cell and dendritic cell development in the mouse thymus
    • Shortman K., et al. The linkage between T cell and dendritic cell development in the mouse thymus. Immunol. Rev. 1998, 165:39-46.
    • (1998) Immunol. Rev. , vol.165 , pp. 39-46
    • Shortman, K.1
  • 66
    • 6344281028 scopus 로고    scopus 로고
    • T cell developmental biology
    • Lippincott, Williams and Wilkins, W.E. Paul (Ed.)
    • Rothenberg E.V., et al. T cell developmental biology. Fundamental Immunology 2003, 259-301. Lippincott, Williams and Wilkins. 5th edn. W.E. Paul (Ed.).
    • (2003) Fundamental Immunology , pp. 259-301
    • Rothenberg, E.V.1
  • 67
    • 0027305022 scopus 로고
    • Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation
    • Matsuzaki Y., et al. Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation. J. Exp. Med. 1993, 178:1283-1292.
    • (1993) J. Exp. Med. , vol.178 , pp. 1283-1292
    • Matsuzaki, Y.1
  • 68
    • 14944341196 scopus 로고    scopus 로고
    • The earliest subpopulation of mouse thymocytes contains potent T, significant macrophage, and natural killer cell but no B-lymphocyte potential
    • Balciunaite G., et al. The earliest subpopulation of mouse thymocytes contains potent T, significant macrophage, and natural killer cell but no B-lymphocyte potential. Blood 2005, 105:1930-1936.
    • (2005) Blood , vol.105 , pp. 1930-1936
    • Balciunaite, G.1
  • 69
    • 0035873725 scopus 로고    scopus 로고
    • Generation of macrophages from early T progenitors in vitro
    • Lee C.K., et al. Generation of macrophages from early T progenitors in vitro. J. Immunol. 2001, 166:5964-5969.
    • (2001) J. Immunol. , vol.166 , pp. 5964-5969
    • Lee, C.K.1
  • 70
    • 1242298592 scopus 로고    scopus 로고
    • B lineage-specific regulation of V(D)J recombinase activity is established in common lymphoid progenitors
    • Borghesi L., et al. B lineage-specific regulation of V(D)J recombinase activity is established in common lymphoid progenitors. J. Exp. Med. 2004, 199:491-502.
    • (2004) J. Exp. Med. , vol.199 , pp. 491-502
    • Borghesi, L.1
  • 71
    • 33749263001 scopus 로고    scopus 로고
    • A variable immunoreceptor in a subpopulation of human neutrophils
    • Puellmann K., et al. A variable immunoreceptor in a subpopulation of human neutrophils. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:14441-14446.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 14441-14446
    • Puellmann, K.1
  • 72
    • 0037007023 scopus 로고    scopus 로고
    • Lineage infidelity in myeloid cells with TCR gene rearrangement: a latent developmental potential of proT cells revealed by ectopic cytokine receptor signaling
    • King A.G., et al. Lineage infidelity in myeloid cells with TCR gene rearrangement: a latent developmental potential of proT cells revealed by ectopic cytokine receptor signaling. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:4508-4513.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 4508-4513
    • King, A.G.1
  • 73
    • 33846257739 scopus 로고    scopus 로고
    • Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors
    • Laiosa C.V., et al. Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors. Immunity 2006, 25:731-744.
    • (2006) Immunity , vol.25 , pp. 731-744
    • Laiosa, C.V.1
  • 74
    • 34250203551 scopus 로고    scopus 로고
    • Negotiation of the T lineage fate decision by transcription-factor interplay and microenvironmental signals
    • Rothenberg E.V. Negotiation of the T lineage fate decision by transcription-factor interplay and microenvironmental signals. Immunity 2007, 26:690-702.
    • (2007) Immunity , vol.26 , pp. 690-702
    • Rothenberg, E.V.1
  • 75
    • 34250217913 scopus 로고    scopus 로고
    • Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3
    • Taghon T., et al. Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3. Nat. Immunol. 2007, 8:845-855.
    • (2007) Nat. Immunol. , vol.8 , pp. 845-855
    • Taghon, T.1
  • 76
    • 4344572135 scopus 로고    scopus 로고
    • Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions
    • Schmitt T.M., et al. Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions. J. Exp. Med. 2004, 200:469-479.
    • (2004) J. Exp. Med. , vol.200 , pp. 469-479
    • Schmitt, T.M.1
  • 77
    • 0025200110 scopus 로고
    • T cell differentiation in thymus organ cultures
    • Jenkinson E.J., Owen J.J. T cell differentiation in thymus organ cultures. Semin. Immunol. 1990, 2:51-58.
    • (1990) Semin. Immunol. , vol.2 , pp. 51-58
    • Jenkinson, E.J.1    Owen, J.J.2
  • 78
    • 0027465451 scopus 로고
    • MHC class II-positive epithelium and mesenchyme cells are both required for T cell development in the thymus
    • Anderson G., et al. MHC class II-positive epithelium and mesenchyme cells are both required for T cell development in the thymus. Nature 1993, 362:70-73.
    • (1993) Nature , vol.362 , pp. 70-73
    • Anderson, G.1
  • 79
    • 16644374913 scopus 로고    scopus 로고
    • A new clonal assay system for lymphoid and myeloid lineages
    • Kawamoto H., Katsura Y. A new clonal assay system for lymphoid and myeloid lineages. Methods Mol. Med. 2005, 105:345-358.
    • (2005) Methods Mol. Med. , vol.105 , pp. 345-358
    • Kawamoto, H.1    Katsura, Y.2
  • 80
    • 34247882592 scopus 로고    scopus 로고
    • Zoned out: functional mapping of stromal signaling microenvironments in the thymus
    • Petrie H.T., Zuniga-Pflucker J.C. Zoned out: functional mapping of stromal signaling microenvironments in the thymus. Annu. Rev. Immunol. 2007, 25:649-679.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 649-679
    • Petrie, H.T.1    Zuniga-Pflucker, J.C.2
  • 81
    • 0028048369 scopus 로고
    • Generation of lymphohematopoietic cells from embryonic stem cells in culture
    • Nakano T., et al. Generation of lymphohematopoietic cells from embryonic stem cells in culture. Science 1994, 265:1098-1101.
    • (1994) Science , vol.265 , pp. 1098-1101
    • Nakano, T.1
  • 82
    • 33846216011 scopus 로고    scopus 로고
    • Bone marrow-derived hemopoietic precursors commit to the T cell lineage only after arrival in the thymic microenvironment
    • Heinzel K., et al. Bone marrow-derived hemopoietic precursors commit to the T cell lineage only after arrival in the thymic microenvironment. J. Immunol. 2007, 178:858-868.
    • (2007) J. Immunol. , vol.178 , pp. 858-868
    • Heinzel, K.1
  • 83
    • 63949087179 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation without irradiation
    • Waskow C., et al. Hematopoietic stem cell transplantation without irradiation. Nat. Methods 2009, 6:267-269.
    • (2009) Nat. Methods , vol.6 , pp. 267-269
    • Waskow, C.1
  • 84
    • 3242747324 scopus 로고    scopus 로고
    • Regulation of thymus size by competition for stromal niches among early T cell progenitors
    • Prockop S.E., Petrie H.T. Regulation of thymus size by competition for stromal niches among early T cell progenitors. J. Immunol. 2004, 173:1604-1611.
    • (2004) J. Immunol. , vol.173 , pp. 1604-1611
    • Prockop, S.E.1    Petrie, H.T.2
  • 85
    • 85012710561 scopus 로고
    • Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors
    • Goldschneider I., et al. Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors. J. Exp. Med. 1986, 163:1-17.
    • (1986) J. Exp. Med. , vol.163 , pp. 1-17
    • Goldschneider, I.1
  • 86
    • 0027502561 scopus 로고
    • Fc gamma RII/III and CD2 expression mark distinct subpopulations of immature CD4-CD8- murine thymocytes: in vivo developmental kinetics and T cell receptor beta chain rearrangement status
    • Rodewald H.R., et al. Fc gamma RII/III and CD2 expression mark distinct subpopulations of immature CD4-CD8- murine thymocytes: in vivo developmental kinetics and T cell receptor beta chain rearrangement status. J. Exp. Med. 1993, 177:1079-1092.
    • (1993) J. Exp. Med. , vol.177 , pp. 1079-1092
    • Rodewald, H.R.1
  • 87
    • 0025607947 scopus 로고
    • Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4 and CD8 acquisition in vivo and in vitro
    • Petrie H.T., et al. Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4 and CD8 acquisition in vivo and in vitro. J. Exp. Med. 1990, 172:1583-1588.
    • (1990) J. Exp. Med. , vol.172 , pp. 1583-1588
    • Petrie, H.T.1
  • 88
    • 0029959207 scopus 로고    scopus 로고
    • Conditional gene targeting
    • Rajewsky K., et al. Conditional gene targeting. J. Clin. Invest. 1996, 98:600-603.
    • (1996) J. Clin. Invest. , vol.98 , pp. 600-603
    • Rajewsky, K.1
  • 89
    • 0037001977 scopus 로고    scopus 로고
    • Cre/lox: one more step in the taming of the genome
    • Sauer B. Cre/lox: one more step in the taming of the genome. Endocrine 2002, 19:221-228.
    • (2002) Endocrine , vol.19 , pp. 221-228
    • Sauer, B.1
  • 90
    • 11344273450 scopus 로고    scopus 로고
    • DNA recombination with a heterospecific Cre homolog identified from comparison of the pac-c1 regions of P1-related phages
    • Sauer B., McDermott J. DNA recombination with a heterospecific Cre homolog identified from comparison of the pac-c1 regions of P1-related phages. Nucleic Acids Res. 2004, 32:6086-6095.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 6086-6095
    • Sauer, B.1    McDermott, J.2
  • 91
    • 34347398120 scopus 로고    scopus 로고
    • HIV-1 proviral DNA excision using an evolved recombinase
    • Sarkar I., et al. HIV-1 proviral DNA excision using an evolved recombinase. Science 2007, 316:1912-1915.
    • (2007) Science , vol.316 , pp. 1912-1915
    • Sarkar, I.1
  • 92
    • 3042856262 scopus 로고    scopus 로고
    • Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
    • Srinivas S., et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev. Biol. 2001, 1:4.
    • (2001) BMC Dev. Biol. , vol.1 , pp. 4
    • Srinivas, S.1
  • 93
    • 33846365298 scopus 로고    scopus 로고
    • Faithful activation of an extra-bright red fluorescent protein in " knock-in" Cre-reporter mice ideally suited for lineage tracing studies
    • Luche H., et al. Faithful activation of an extra-bright red fluorescent protein in " knock-in" Cre-reporter mice ideally suited for lineage tracing studies. Eur. J. Immunol. 2007, 37:43-53.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 43-53
    • Luche, H.1
  • 94
    • 0029962975 scopus 로고    scopus 로고
    • Inducible site-directed recombination in mouse embryonic stem cells
    • Zhang Y., et al. Inducible site-directed recombination in mouse embryonic stem cells. Nucleic Acids Res. 1996, 24:543-548.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 543-548
    • Zhang, Y.1
  • 95
    • 33748774926 scopus 로고    scopus 로고
    • Testing gene function early in the B cell lineage in mb1-cre mice
    • Hobeika E., et al. Testing gene function early in the B cell lineage in mb1-cre mice. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:13789-13794.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 13789-13794
    • Hobeika, E.1
  • 96
    • 0344197969 scopus 로고    scopus 로고
    • The LMO2 T cell oncogene is activated via chromosomal translocations or retroviral insertion during gene therapy but has no mandatory role in normal T cell development
    • McCormack M.P., et al. The LMO2 T cell oncogene is activated via chromosomal translocations or retroviral insertion during gene therapy but has no mandatory role in normal T cell development. Mol. Cell Biol. 2003, 23:9003-9013.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 9003-9013
    • McCormack, M.P.1
  • 97
    • 34250694086 scopus 로고    scopus 로고
    • Vagaries of conditional gene targeting
    • Schmidt-Supprian M., Rajewsky K. Vagaries of conditional gene targeting. Nat. Immunol. 2007, 8:665-668.
    • (2007) Nat. Immunol. , vol.8 , pp. 665-668
    • Schmidt-Supprian, M.1    Rajewsky, K.2


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