A B220+ CD117+ CD19- hematopoietic progenitor with potent lymphoid and myeloid developmental potential

European Journal of Immunology

Volumn 35, Issue 7, 2005, Pages 2019-2030

  Balciunaite, Gina ^a   Ceredig, Rod ^b   Massa, Steffen ^a   Rolink, Antonius G ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b INSERM   (France)

Author keywords

B cell development; Lymphopoiesis; Myeloid development; Progenitor cells; T cell development

Indexed keywords

CD19 ANTIGEN; CD45 ANTIGEN; CYTOKINE; DELTA LIKE 1 PROTEIN; NOTCH RECEPTOR; STEM CELL FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CELL LINEAGE; CELL MATURATION; CELL SELECTION; CELL SUBPOPULATION; CONTROLLED STUDY; DILUTION; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; LYMPHOID CELL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROMA CELL; T LYMPHOCYTE; WILD TYPE;

ANIMALS; ANTIGENS; ANTIGENS, CD19; ANTIGENS, CD45; ANTIGENS, SURFACE; B-LYMPHOCYTES; CELL DIFFERENTIATION; FEMALE; HEMATOPOIETIC STEM CELLS; LECTINS, C-TYPE; LYMPHOID TISSUE; MICE; MICE, CONGENIC; MICE, INBRED BALB C; MICE, INBRED C57BL; MYELOID CELLS; PROTEINS; PROTO-ONCOGENE PROTEINS C-KIT; T-LYMPHOCYTES;

EID: 22544451234     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200526318     Document Type: Article

References (30)

1. Ikuta, K., Uchida, N., Friedman, J. and Weissman, I. L., Lymphocyte development from stem cells. Annu. Rev. Immunol. 1992. 10: 759-783.
2. Weissman, I.L., Stemcells: units of development, units of regeneration, and units in evolution. Cell 2000. 100: 157-168.
3. Kondo, M., Weissman, I. L. and Akashi, K., Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997. 91: 661-672.
4. Kondo, M., Scherer, D. C., King, A. G., Manz, M. G. and Weissman, I. L., Lymphocyte development from hematopoietic stem cells. Curr. Opin. Genet. Dev. 2001. 11: 520-526.
5. Rolink, A., Haasner, D., Nishikawa, S. and Melchers, F., Changes in frequencies of clonable pre B cells during life in different lymphoid organs of mice. Blood 1993. 81: 2290-2300.
6. Rolink, A., Kudo, A., Karasuyama, H., Kikuchi, Y. and Melchers, F., Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo. EMBO J. 1991. 10: 327-336.
7. Rolink, A., Grawunder, U., Winkler, T. H., Karasuyama, H. and Melchers, F., IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development. Int. Immunol. 1994. 6: 1257-1264.
8. + cells in routine bone marrow does not express CD19 and contains natural killer cell progenitors. J. Exp. Med. 1996. 183: 187-194.
9. Busslinger, M., Transcriptional control of early B cell development. Annu. Rev. Immunol. 2004. 22: 55-79.
10. Hardy, R., B-cell commitment: deciding on the players. Curr. Opin. Immunol. 2003. 15: 158-165.
11. Schmitt, T. M. and Zuniga-Pflucker, J. C., Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity 2002. 17: 749-756.
12. Zuniga-Pflucker, J. C., T-cell development made simple. Nat. Rev. Immunol. 2004. 4: 67-72.
13. Balciunaite, G., Ceredig, R., Fehling, H. J., Zuniga-Pflucker, J. C. and Rolink, A. G., The role of Notch and IL-7 signaling in early thymocyte proliferation and differentiation. Eur. J. Immunol. 2005. 35: 1292-1300.
14. Porritt, H. E., Rumfelt, L. L., Tabrizifard, S., Schmitt, T. M., Zuniga-Pflucker, J. C. and Petrie, H. T., Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages. Immunity 2004. 20: 735-745.
15. Rolink, A. G., Nutt, S. L., Melchers, F. and Busslinger, M., Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors. Nature 1999. 401: 603-606.
16. Godfrey, D. I., Zlotnik, A. and Suda, T., Phenotypic and functional characterization of c-kit expression during intrathymic T cell development. J. Immunol. 1992. 149: 2281-2285.
17. Ceredig, R. and Rolink, A., A positive look at double negative thymocytes. Nat. Rev. Immunol. 2002
18. Anderson, G. and Jenkinson, E. J., Lymphostromal interactions in thymic development and function. Nat. Rev. Immunol. 2001. 1: 31-40.
19. Nutt, S. L., Heavey, B., Rolink, A. G. and Busslinger, M., Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature 1999. 401: 556-562.
20. Martin, F. and Kearney, J. F., Marginal-zone B cells. Nat. Rev. Immunol. 2002. 2: 323-335.
21. Perry, S. S., Wang, H., Pierce, L. J., Yang, A. M., Tsai, S. and Spangrude, G. J., L-selectin defines a bone marrow analog to the thymic early T-lineage progenitor. Blood 2004. 103: 2990-2996.
22. Medina, K. L., Garrett, K. P., Thompson, L. F., Rossi, M. I., Payne, K. J. and Kincade, P. W., Identification of very early lymphoid precursors in bone marrow and their regulation by estrogen. Nat. Immunol. 2001. 2: 718-724.
23. Clarke, A. G. and Kendall, M. D., The thymus in pregnancy: the interplay of neural, endocrine and immune influences. Immunol. Today 1994. 15: 545-551.
24. + lymphoid-restricted bone marrow cells with T precursor potential. Nat. Immunol. 2003. 4: 866-873.
25. Asselin-Paturel, C., Boonstra, A., Dalod, M., Durand, I., Yessaad, N., Dezutter-Dambuyant, C., Vicari, A. et al., Mouse type IIFN-producing cells are immature APCs with plasmacytoid morphology. Nat. Immunol. 2001. 2: 1144-1150.
26. Nikolic, T., Dingjan, G. M., Leenen, P. J. and Hendriks, R. W., A subfraction of B220(+) cells in murine bone marrow and spleen does not belong to the B cell lineage but has dendritic cell characteristics. Eur. J. Immunol. 2002. 32: 686-692.
27. + dendritic cells endowed with type 1 interferon production capacity and tolerogenic potential. Blood 2002. 100: 383-390.
28. Nutt, S. L., Urbanek, P., Rolink, A. and Busslinger, M., Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus. Genes Dev. 1997. 11: 476-491.
29. Nakano, T., Kodama, H. and Honjo, T., Generation of lymphohematopoietic cells from embryonic stem cells in culture. Science 1994. 265: 1098-1101.
30. Rolink, A. G., Andersson, J. and Melchers, F., Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity. Eur. J. Immunol. 1998. 28: 3738-3748.