ATP-mediated protein kinase B Akt/mammalian target of rapamycin mTOR/p70 ribosomal S6 protein p70S6 kinase signaling pathway activation promotes improvement of locomotor function after spinal cord injury in rats

Neuroscience

Volumn 169, Issue 3, 2010, Pages 1046-1062

  Hu, L Y ^a,b   Sun, Z G ^a,b   Wen, Y M ^a,b   Cheng, G Z ^b   Wang, S L ^a   Zhao, H B ^b   Zhang, X R ^c  

^a LANZHOU UNIVERSITY   (China)

^b LANZHOU GENERAL HOSPITAL   (China)

^c Jingdezhen 333001   (China)

Author keywords

Locomotor functional recovery; MTOR; Nervous system injury; Rapamycin; Signal transduction pathway; Spine

Indexed keywords

ADENOSINE TRIPHOSPHATE; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; NESTIN; NEUROFILAMENT 200; NEUROFILAMENT PROTEIN; NEURON SPECIFIC ENOLASE; PROTEIN KINASE B; RAPAMYCIN; S6 KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; FUNCTIONAL ASSESSMENT; GENE ACTIVATION; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LOCOMOTION; MOTOR PERFORMANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPINAL CORD INJURY; TREATMENT DURATION; TREATMENT RESPONSE; WESTERN BLOTTING;

EID: 77955273588     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.05.046     Document Type: Article

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