Structure-based in silico design of aHigh-Affinity dipeptide inhibitor for novel protein drug target shikimate kinase of mycobacterium tuberculosis

Chemical Biology and Drug Design

Volumn 76, Issue 3, 2010, Pages 277-284

  Kumar, Manoj ^a   Verma, Shikha ^a   Sharma, Sujata ^a   Srinivasan, Alagiri ^a   Singh, Tej P ^a   Kaur, Punit ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

docking; Mycobacterium tuberculosis; peptide inhibitor; shikimate kinase; structure based drug design

Indexed keywords

DIPEPTIDE; ENZYME INHIBITOR; PHOSPHOTRANSFERASE; SHIKIMATE KINASE; SHIKIMATE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG ACTIVITY; DRUG DESIGN; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; ENZYME INHIBITOR INTERACTION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL;

ANTITUBERCULAR AGENTS; BINDING SITES; DIPEPTIDES; DRUG DESIGN; ENZYME INHIBITORS; HYDROGEN BONDING; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); STRUCTURE-ACTIVITY RELATIONSHIP;

MAMMALIA; MYCOBACTERIUM TUBERCULOSIS;

EID: 77955250106     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2010.01005.x     Document Type: Article

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