-
1
-
-
2642553258
-
Target identification in chemical genetics: The (often) missing link
-
Burdine, L.; Kodadek, T. Target identification in chemical genetics: the (often) missing link Chem. Biol. 2004, 11 (5) 593-597
-
(2004)
Chem. Biol.
, vol.11
, Issue.5
, pp. 593-597
-
-
Burdine, L.1
Kodadek, T.2
-
2
-
-
35048856423
-
Simultaneous arming and structure/activity studies of natural products employing O-H insertions: An expedient and versatile strategy for natural products-based chemical genetics
-
Peddibhotla, S.; Dang, Y.; Liu, J. O.; Romo, D. Simultaneous arming and structure/activity studies of natural products employing O-H insertions: an expedient and versatile strategy for natural products-based chemical genetics J. Am. Chem. Soc. 2007, 129 (40) 12222-12231
-
(2007)
J. Am. Chem. Soc.
, vol.129
, Issue.40
, pp. 12222-12231
-
-
Peddibhotla, S.1
Dang, Y.2
Liu, J.O.3
Romo, D.4
-
3
-
-
33846963550
-
Marked small molecule libraries: A truncated approach to molecular probe design
-
Inverarity, I. A.; Hulme, A. N. Marked small molecule libraries: a truncated approach to molecular probe design Org. Biomol. Chem. 2007, 5 (4) 636-643
-
(2007)
Org. Biomol. Chem.
, vol.5
, Issue.4
, pp. 636-643
-
-
Inverarity, I.A.1
Hulme, A.N.2
-
4
-
-
38649096952
-
Click imaging of biochemical processes in living systems
-
Fokin, V. V. Click imaging of biochemical processes in living systems ACS Chem. Biol. 2007, 2 (12) 775-778
-
(2007)
ACS Chem. Biol.
, vol.2
, Issue.12
, pp. 775-778
-
-
Fokin, V.V.1
-
5
-
-
33947500247
-
Chemical tools for biomolecular imaging
-
Johnsson, N.; Johnsson, K. Chemical tools for biomolecular imaging ACS Chem. Biol. 2007, 2 (1) 31-38
-
(2007)
ACS Chem. Biol.
, vol.2
, Issue.1
, pp. 31-38
-
-
Johnsson, N.1
Johnsson, K.2
-
6
-
-
33846926304
-
Fluorescence imaging in vivo: Recent advances
-
Rao, J.; Dragulescu-Andrasi, A.; Yao, H. Fluorescence imaging in vivo: recent advances Curr. Opin. Biotechnol. 2007, 18 (1) 17-25
-
(2007)
Curr. Opin. Biotechnol.
, vol.18
, Issue.1
, pp. 17-25
-
-
Rao, J.1
Dragulescu-Andrasi, A.2
Yao, H.3
-
7
-
-
33846807650
-
Tagging and detection strategies for activity-based proteomics
-
Sadaghiani, A. M.; Verhelst, S. H.; Bogyo, M. Tagging and detection strategies for activity-based proteomics Curr. Opin. Chem. Biol. 2007, 11 (1) 20-28
-
(2007)
Curr. Opin. Chem. Biol.
, vol.11
, Issue.1
, pp. 20-28
-
-
Sadaghiani, A.M.1
Verhelst, S.H.2
Bogyo, M.3
-
8
-
-
36749028242
-
Copper-free click chemistry for dynamic in vivo imaging
-
Baskin, J. M.; Prescher, J. A.; Laughlin, S. T.; Agard, N. J.; Chang, P. V.; Miller, I. A.; Lo, A.; Codelli, J. A.; Bertozzi, C. R. Copper-free click chemistry for dynamic in vivo imaging Proc. Natl. Acad. Sci. U.S.A. 2007, 104 (43) 16793-16797
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, Issue.43
, pp. 16793-16797
-
-
Baskin, J.M.1
Prescher, J.A.2
Laughlin, S.T.3
Agard, N.J.4
Chang, P.V.5
Miller, I.A.6
Lo, A.7
Codelli, J.A.8
Bertozzi, C.R.9
-
9
-
-
9344227358
-
A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems
-
Agard, N. J.; Prescher, J. A.; Bertozzi, C. R. A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems J. Am. Chem. Soc. 2004, 126 (46) 15046-15047
-
(2004)
J. Am. Chem. Soc.
, vol.126
, Issue.46
, pp. 15046-15047
-
-
Agard, N.J.1
Prescher, J.A.2
Bertozzi, C.R.3
-
10
-
-
73649129882
-
In vivo imaging of Caenorhabditis elegans glycans
-
Laughlin, S. T.; Bertozzi, C. R. In vivo imaging of Caenorhabditis elegans glycans ACS Chem. Biol. 2009, 4 (12) 1068-1072
-
(2009)
ACS Chem. Biol.
, vol.4
, Issue.12
, pp. 1068-1072
-
-
Laughlin, S.T.1
Bertozzi, C.R.2
-
11
-
-
43249099890
-
In vivo imaging of membrane-associated glycans in developing zebrafish
-
Laughlin, S. T.; Baskin, J. M.; Amacher, S. L.; Bertozzi, C. R. In vivo imaging of membrane-associated glycans in developing zebrafish Science 2008, 320 (5876) 664-667
-
(2008)
Science
, vol.320
, Issue.5876
, pp. 664-667
-
-
Laughlin, S.T.1
Baskin, J.M.2
Amacher, S.L.3
Bertozzi, C.R.4
-
12
-
-
4344704630
-
Chemical remodelling of cell surfaces in living animals
-
Prescher, J. A.; Dube, D. H.; Bertozzi, C. R. Chemical remodelling of cell surfaces in living animals Nature 2004, 430 (7002) 873-877
-
(2004)
Nature
, vol.430
, Issue.7002
, pp. 873-877
-
-
Prescher, J.A.1
Dube, D.H.2
Bertozzi, C.R.3
-
13
-
-
34447536672
-
Imaging cell surface glycans with bioorthogonal chemical reporters
-
Chang, P. V.; Prescher, J. A.; Hangauer, M. J.; Bertozzi, C. R. Imaging cell surface glycans with bioorthogonal chemical reporters J. Am. Chem. Soc. 2007, 129 (27) 8400-8401
-
(2007)
J. Am. Chem. Soc.
, vol.129
, Issue.27
, pp. 8400-8401
-
-
Chang, P.V.1
Prescher, J.A.2
Hangauer, M.J.3
Bertozzi, C.R.4
-
14
-
-
70349917806
-
Bioorthogonal chemistry: Fishing for selectivity in a sea of functionality
-
Sletten, E. M.; Bertozzi, C. R. Bioorthogonal chemistry: fishing for selectivity in a sea of functionality Angew. Chem., Int. Ed. 2009, 48 (38) 6974-6998
-
(2009)
Angew. Chem., Int. Ed.
, vol.48
, Issue.38
, pp. 6974-6998
-
-
Sletten, E.M.1
Bertozzi, C.R.2
-
15
-
-
0347379902
-
Separate roles for the Golgi apparatus and lysosomes in the sequestration of drugs in the multidrug-resistant human leukemic cell line HL-60
-
Gong, Y.; Duvvuri, M.; Krise, J. P. Separate roles for the Golgi apparatus and lysosomes in the sequestration of drugs in the multidrug-resistant human leukemic cell line HL-60 J. Biol. Chem. 2003, 278 (50) 50234-50239
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.50
, pp. 50234-50239
-
-
Gong, Y.1
Duvvuri, M.2
Krise, J.P.3
-
16
-
-
3542992044
-
Weak base permeability characteristics influence the intracellular sequestration site in the multidrug-resistant human leukemic cell line HL-60
-
Duvvuri, M.; Gong, Y.; Chatterji, D.; Krise, J. P. Weak base permeability characteristics influence the intracellular sequestration site in the multidrug-resistant human leukemic cell line HL-60 J. Biol. Chem. 2004, 279 (31) 32367-32372
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.31
, pp. 32367-32372
-
-
Duvvuri, M.1
Gong, Y.2
Chatterji, D.3
Krise, J.P.4
-
17
-
-
17244366637
-
Intracellular drug sequestration events associated with the emergence of multidrug resistance: A mechanistic review
-
Duvvuri, M.; Krise, J. P. Intracellular drug sequestration events associated with the emergence of multidrug resistance: a mechanistic review Front. Biosci. 2005, 10, 1499-1509
-
(2005)
Front. Biosci.
, vol.10
, pp. 1499-1509
-
-
Duvvuri, M.1
Krise, J.P.2
-
18
-
-
28544443286
-
A chemical strategy to manipulate the intracellular localization of drugs in resistant cancer cells
-
Duvvuri, M.; Konkar, S.; Funk, R. S.; Krise, J. M.; Krise, J. P. A chemical strategy to manipulate the intracellular localization of drugs in resistant cancer cells Biochemistry 2005, 44 (48) 15743-15749
-
(2005)
Biochemistry
, vol.44
, Issue.48
, pp. 15743-15749
-
-
Duvvuri, M.1
Konkar, S.2
Funk, R.S.3
Krise, J.M.4
Krise, J.P.5
-
19
-
-
0037672857
-
Supertargeted chemistry: Identifying relationships between molecular structures and their sub-cellular distribution
-
Rosania, G. R. Supertargeted chemistry: identifying relationships between molecular structures and their sub-cellular distribution Curr. Top. Med. Chem. 2003, 3 (6) 659-685
-
(2003)
Curr. Top. Med. Chem.
, vol.3
, Issue.6
, pp. 659-685
-
-
Rosania, G.R.1
-
20
-
-
2942690158
-
Analysis of binding reactions by fluorescence recovery after photobleaching
-
Sprague, B. L.; Pego, R. L.; Stavreva, D. A.; McNally, J. G. Analysis of binding reactions by fluorescence recovery after photobleaching Biophys. J. 2004, 86 (6) 3473-3495
-
(2004)
Biophys. J.
, vol.86
, Issue.6
, pp. 3473-3495
-
-
Sprague, B.L.1
Pego, R.L.2
Stavreva, D.A.3
McNally, J.G.4
-
21
-
-
0141530988
-
Three-dimensional fluorescence recovery after photobleaching with the confocal scanning laser microscope
-
Braeckmans, K.; Peeters, L.; Sanders, N. N.; De Smedt, S. C.; Demeester, J. Three-dimensional fluorescence recovery after photobleaching with the confocal scanning laser microscope Biophys. J. 2003, 85 (4) 2240-2252
-
(2003)
Biophys. J.
, vol.85
, Issue.4
, pp. 2240-2252
-
-
Braeckmans, K.1
Peeters, L.2
Sanders, N.N.3
De Smedt, S.C.4
Demeester, J.5
-
22
-
-
13244291467
-
FRAP analysis of binding: Proper and fitting
-
Sprague, B. L.; McNally, J. G. FRAP analysis of binding: proper and fitting Trends Cell Biol. 2005, 15 (2) 84-91
-
(2005)
Trends Cell Biol.
, vol.15
, Issue.2
, pp. 84-91
-
-
Sprague, B.L.1
McNally, J.G.2
-
23
-
-
34848924589
-
A concise synthesis of the Pennsylvania Green fluorophore and labeling of intracellular targets with O6-benzylguanine derivatives
-
Mottram, L. F.; Maddox, E.; Schwab, M.; Beaufils, F.; Peterson, B. R. A concise synthesis of the Pennsylvania Green fluorophore and labeling of intracellular targets with O6-benzylguanine derivatives Org. Lett. 2007, 9 (19) 3741-3744
-
(2007)
Org. Lett.
, vol.9
, Issue.19
, pp. 3741-3744
-
-
Mottram, L.F.1
Maddox, E.2
Schwab, M.3
Beaufils, F.4
Peterson, B.R.5
-
24
-
-
26444441453
-
Alkyl-substituted polyaminohydroxamic acids: A novel class of targeted histone deacetylase inhibitors
-
Varghese, S.; Gupta, D.; Baran, T.; Jiemjit, A.; Gore, S. D.; Casero, R. A., Jr.; Woster, P. M. Alkyl-substituted polyaminohydroxamic acids: a novel class of targeted histone deacetylase inhibitors J. Med. Chem. 2005, 48 (20) 6350-6365
-
(2005)
J. Med. Chem.
, vol.48
, Issue.20
, pp. 6350-6365
-
-
Varghese, S.1
Gupta, D.2
Baran, T.3
Jiemjit, A.4
Gore, S.D.5
Casero Jr., R.A.6
Woster, P.M.7
-
25
-
-
0141782224
-
Conformative coupling of two conformational molecular switches
-
Karle, M.; Bockelmann, D.; Schumann, D.; Griesinger, C.; Koert, U. Conformative coupling of two conformational molecular switches Angew. Chem., Int. Ed. 2003, 42 (37) 4546-4549
-
(2003)
Angew. Chem., Int. Ed.
, vol.42
, Issue.37
, pp. 4546-4549
-
-
Karle, M.1
Bockelmann, D.2
Schumann, D.3
Griesinger, C.4
Koert, U.5
-
26
-
-
0016260069
-
Commentary. Lysosomotropic agents
-
de Duve, C.; de Barsy, T.; Poole, B.; Trouet, A.; Tulkens, P.; Van Hoof, F. Commentary. Lysosomotropic agents Biochem. Pharmacol. 1974, 23 (18) 2495-2531
-
(1974)
Biochem. Pharmacol.
, vol.23
, Issue.18
, pp. 2495-2531
-
-
De Duve, C.1
De Barsy, T.2
Poole, B.3
Trouet, A.4
Tulkens, P.5
Van Hoof, F.6
-
27
-
-
0035892357
-
Impact of the basic amine on the biological activity and intracellular distribution of an aza-anthrapyrazole: BBR 3422
-
Chou, K. M.; Paul Krapcho, A.; Hacker, M. P. Impact of the basic amine on the biological activity and intracellular distribution of an aza-anthrapyrazole: BBR 3422 Biochem. Pharmacol. 2001, 62 (10) 1337-1343
-
(2001)
Biochem. Pharmacol.
, vol.62
, Issue.10
, pp. 1337-1343
-
-
Chou, K.M.1
Paul Krapcho, A.2
Hacker, M.P.3
-
28
-
-
1642579666
-
A cell fractionation approach for the quantitative analysis of subcellular drug disposition
-
Duvvuri, M.; Feng, W.; Mathis, A.; Krise, J. P. A cell fractionation approach for the quantitative analysis of subcellular drug disposition Pharm. Res. 2004, 21 (1) 26-32
-
(2004)
Pharm. Res.
, vol.21
, Issue.1
, pp. 26-32
-
-
Duvvuri, M.1
Feng, W.2
Mathis, A.3
Krise, J.P.4
-
29
-
-
0024733168
-
Fluorescence self-quenching of the molecular forms of Rhodamine B in aqueous and ethanolic solutions
-
Arbeloa, F. L.; Ojeda, P. R.; Arbeloa, I. L. Fluorescence self-quenching of the molecular forms of Rhodamine B in aqueous and ethanolic solutions J. Lumin. 1989, 44, 105-112
-
(1989)
J. Lumin.
, vol.44
, pp. 105-112
-
-
Arbeloa, F.L.1
Ojeda, P.R.2
Arbeloa, I.L.3
-
30
-
-
0345104309
-
Intracellular sorting and the maintenance of cellular compartments
-
In, 2nd ed.;, Ed.; Garland Publishing, Inc.: New York, NY,; pp -' 479
-
Alberts, B.; Bray, D.; Lewis, J. W.; Raff, M.; Roberts, K.; Watson, J. D. Intracellular sorting and the maintenance of cellular compartments. In Molecular Biology of the Cell, 2nd ed.; Robertson, M., Ed.; Garland Publishing, Inc.: New York, NY, 1989; pp 405 -' 479.
-
(1989)
Molecular Biology of the Cell
, pp. 405
-
-
Alberts, B.1
Bray, D.2
Lewis, J.W.3
Raff, M.4
Roberts, K.5
Watson, J.D.6
Robertson, M.7
-
31
-
-
0037046517
-
Distribution of furamidine analogues in tumor cells: Influence of the number of positive charges
-
Lansiaux, A.; Dassonneville, L.; Facompre, M.; Kumar, A.; Stephens, C. E.; Bajic, M.; Tanious, F.; Wilson, W. D.; Boykin, D. W.; Bailly, C. Distribution of furamidine analogues in tumor cells: influence of the number of positive charges J. Med. Chem. 2002, 45 (10) 1994-2002
-
(2002)
J. Med. Chem.
, vol.45
, Issue.10
, pp. 1994-2002
-
-
Lansiaux, A.1
Dassonneville, L.2
Facompre, M.3
Kumar, A.4
Stephens, C.E.5
Bajic, M.6
Tanious, F.7
Wilson, W.D.8
Boykin, D.W.9
Bailly, C.10
-
32
-
-
0025316676
-
Interaction of molecular probes with living cells and tissues. Part 2. A structure-activity analysis of mitochondrial staining by cationic probes, and a discussion of the synergistic nature of image-based and biochemical approaches
-
Rashid, F.; Horobin, R. W. Interaction of molecular probes with living cells and tissues. Part 2. A structure-activity analysis of mitochondrial staining by cationic probes, and a discussion of the synergistic nature of image-based and biochemical approaches Histochemistry 1990, 94 (3) 303-308
-
(1990)
Histochemistry
, vol.94
, Issue.3
, pp. 303-308
-
-
Rashid, F.1
Horobin, R.W.2
-
33
-
-
33845313861
-
A new approach for enhancing differential selectivity of drugs to cancer cells
-
Duvvuri, M.; Konkar, S.; Hong, K. H.; Blagg, B. S.; Krise, J. P. A new approach for enhancing differential selectivity of drugs to cancer cells ACS Chem. Biol. 2006, 1 (5) 309-315
-
(2006)
ACS Chem. Biol.
, vol.1
, Issue.5
, pp. 309-315
-
-
Duvvuri, M.1
Konkar, S.2
Hong, K.H.3
Blagg, B.S.4
Krise, J.P.5
-
34
-
-
29244474340
-
Niemann-Pick C1 protein facilitates the efflux of the anticancer drug daunorubicin from cells according to a novel vesicle-mediated pathway
-
Gong, Y.; Duvvuri, M.; Duncan, M. B.; Liu, J.; Krise, J. P. Niemann-Pick C1 protein facilitates the efflux of the anticancer drug daunorubicin from cells according to a novel vesicle-mediated pathway J. Pharmacol. Exp. Ther. 2006, 316 (1) 242-247
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.316
, Issue.1
, pp. 242-247
-
-
Gong, Y.1
Duvvuri, M.2
Duncan, M.B.3
Liu, J.4
Krise, J.P.5
-
35
-
-
0034747783
-
Effect of probenecid on fluorescein transport in the central nervous system using in vitro and in vivo models
-
Sun, H.; Miller, D. W.; Elmquist, W. F. Effect of probenecid on fluorescein transport in the central nervous system using in vitro and in vivo models Pharm. Res. 2001, 18 (11) 1542-1549
-
(2001)
Pharm. Res.
, vol.18
, Issue.11
, pp. 1542-1549
-
-
Sun, H.1
Miller, D.W.2
Elmquist, W.F.3
-
36
-
-
0022476714
-
Permeability of small nonelectrolytes through lipid bilayer membranes
-
Walter, A.; Gutknecht, J. Permeability of small nonelectrolytes through lipid bilayer membranes J. Membr. Biol. 1986, 90 (3) 207-217
-
(1986)
J. Membr. Biol.
, vol.90
, Issue.3
, pp. 207-217
-
-
Walter, A.1
Gutknecht, J.2
-
37
-
-
56049083999
-
Computational model for predicting chemical substituent effects on passive drug permeability across parallel artificial membranes
-
Acharya, C.; Seo, P. R.; Polli, J. E.; MacKerell, A. D., Jr. Computational model for predicting chemical substituent effects on passive drug permeability across parallel artificial membranes Mol. Pharmaceutics 2008, 5 (5) 818-828
-
(2008)
Mol. Pharmaceutics
, vol.5
, Issue.5
, pp. 818-828
-
-
Acharya, C.1
Seo, P.R.2
Polli, J.E.3
Mackerell Jr., A.D.4
-
38
-
-
40649111377
-
A chemical method for fast and sensitive detection of DNA synthesis in vivo
-
Salic, A.; Mitchison, T. J. A chemical method for fast and sensitive detection of DNA synthesis in vivo Proc. Natl. Acad. Sci. U.S.A. 2008, 105 (7) 2415-2420
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, Issue.7
, pp. 2415-2420
-
-
Salic, A.1
Mitchison, T.J.2
-
39
-
-
77955258398
-
Handbook of Fluorescent Probes and Research Products
-
In, 8th ed.;, Ed.; Molecular Probes, Inc.: Eugene, OR
-
Haugland, R. P. Handbook of Fluorescent Probes and Research Products; In Probes for Organelles, 8th ed.; Gregory, J., Ed.; Molecular Probes, Inc.: Eugene, OR, 2001.
-
(2001)
Probes for Organelles
-
-
Haugland, R.P.1
Gregory, J.2
|