A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM137, a novel aurora kinase inhibitor

Cancer Research

Volumn 69, Issue 4, 2009, Pages 1509-1516

  Demoe, Joanna H ^a   Santaguida, Stefano ^a   Daum, John R ^a   Musacchio, Andrea ^a,b   Gorbsky, Gary J ^a,c  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^c FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA KINASE INHIBITOR; OM 137; PACLITAXEL; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL SCREENING; CONTROLLED STUDY; DRUG INHIBITION; DRUG POTENTIATION; DRUG STRUCTURE; FEMALE; GROWTH INHIBITION; HUMAN; HUMAN CELL; MITOSIS SPINDLE; PRIORITY JOURNAL; WHOLE CELL;

CELL DIVISION; CHROMOSOMAL INSTABILITY; CHROMOSOMES, HUMAN; ENZYME INHIBITORS; HELA CELLS; HUMANS; HYDRAZONES; MITOSIS; MITOTIC SPINDLE APPARATUS; NOCODAZOLE; PROTEIN-SERINE-THREONINE KINASES; THIAZOLES;

EID: 60549109472     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-3133     Document Type: Article

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