Direct B-alkyl suzuki-miyaura cross-coupling of 2-halopurines. Practical synthesis of ST1535, a potent adenosine A 2A receptor antagonist

Journal of Organic Chemistry

Volumn 75, Issue 15, 2010, Pages 5398-5401

  Bartoccini, Francesca ^a   Cabri, Walter ^b   Celona, Diana ^b   Minetti, Patrizia ^b   Piersanti, Giovanni ^a   Tarzia, Giorgio ^a  

^a UNIVERSITY OF URBINO   (Italy)

^b Sigma Tau SpA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

METAL SPECIES; PALLADIUM-CATALYZED CROSS-COUPLING REACTIONS; RECEPTOR ANTAGONISTS; SUZUKI-MIYAURA CROSS-COUPLING;

ALKYLATION; PALLADIUM;

HYDROCARBONS;

2 CHLORO 6 DIBENZYLAMINOPURINE DERIVATIVE; 2 HALOPURINE DERIVATIVE; ADENOSINE A2A RECEPTOR ANTAGONIST; ALKYL GROUP; BORANE DERIVATIVE; PALLADIUM; PURINE DERIVATIVE; ST 1535; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; QUANTUM YIELD; REACTION ANALYSIS; SUZUKI REACTION;

ADENINE; MAGNETIC RESONANCE SPECTROSCOPY; PURINES; RECEPTOR, ADENOSINE A2A; TRIAZOLES;

EID: 77955125429     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo101027h     Document Type: Article

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