SCOPUS 정보 검색 플랫폼

Volumn 5, Issue 8, 2010, Pages 1215-1220

Bis(7)-tacrine derivatives as multitarget-directed ligands: Focus on anticholinesterase and antiamyloid activities

(10) Bolognesi, Maria Laura a Bartolini, Manuela a Mancini, Francesca a Chiriano, Gianpaolo a Ceccarini, Luisa a Rosini, Michela a Milelli, Andrea a Tumiatti, Vincenzo a Andrisano, Vincenza a Melchiorre, Carlo a

a UNIVERSITY OF BOLOGNA (Italy)

Author keywords

Acetylcholinesterases; Alzheimer's disease; Amyloid beta peptides; Beta secretases; Butyrylcholinesterase; Drug design

Indexed keywords

1,4 BIS[(1,2,3,4 TETRAHYDROACRIDIN 9 YL)AMINOMETHYL]BENZENE; 4,4' BIS[(1,2,3,4 TETRAHYDROACRIDIN 9 YL)AMINOMETHYL]BIPHENYL; 4,4'' BIS[(1,2,3,4 TETRAHYDROACRIDIN 9 YL)AMINOMETHYL][1,1';4',1'']TERPHENYL; AMYLOID BETA PROTEIN[1-42]; BETA SECRETASE 1; BETA SECRETASE INHIBITOR; CHOLINESTERASE INHIBITOR; NOOTROPIC AGENT; TACRINE DERIVATIVE; TERPHENYL DERIVATIVE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CHOLINESTERASE INHIBITION; DRUG MECHANISM; DRUG SYNTHESIS; IC 50; MOLECULAR DOCKING; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PROTEIN INTERACTION;

ACETYLCHOLINESTERASE; AMYLOID; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ACID ENDOPEPTIDASES; BINDING SITES; CHOLINESTERASE INHIBITORS; COMPUTER SIMULATION; DRUG DESIGN; HUMANS; LIGANDS; TACRINE;

EID: 77955103397 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201000086 Document Type: Article

Times cited : (52)

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