The FPR2-induced rise in cytosolic calcium in human neutrophils relies on an emptying of intracellular calcium stores and is inhibited by a gelsolin-derived PIP2-binding peptide

BMC Cell Biology

Volumn 11, Issue , 2010, Pages

  Forsman, Huamei ^a   Dahlgren, Claes ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM CHELATING AGENT; EGTAZIC ACID; FORMYLPEPTIDE RECEPTOR; FORMYLPEPTIDE RECEPTOR 2; GELSOLIN; PEPTIDE DERIVATIVE; PHOSPHATIDYLINOSITOL BINDING PEPTIDE 10; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; SYNTHETIC PEPTIDE; TRYPTOPHANYLLYSYLTYROSYLMETHIONYLVALYLMETHIONINE; UNCLASSIFIED DRUG; ATR PROTEIN, HUMAN; CELL CYCLE PROTEIN; G PROTEIN COUPLED RECEPTOR; GELSOLIN (160 169); GELSOLIN (160-169); MEMBRANE PROTEIN; PATTERN RECOGNITION RECEPTOR; PEPTIDE FRAGMENT; PROTEIN SERINE THREONINE KINASE; SFRP2 PROTEIN, HUMAN;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; NEUTROPHIL; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; INNATE IMMUNITY; METABOLISM; PATHOLOGY; PROTEIN BINDING; SIGNAL TRANSDUCTION;

CALCIUM SIGNALING; CELL CYCLE PROTEINS; CELLS, CULTURED; EGTAZIC ACID; GELSOLIN; HUMANS; IMMUNITY, INNATE; MEMBRANE PROTEINS; NADPH OXIDASE; NEUTROPHILS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PATTERN RECOGNITION; SIGNAL TRANSDUCTION;

EID: 77955097801     PISSN: None     EISSN: 14712121     Source Type: Journal    
DOI: 10.1186/1471-2121-11-52     Document Type: Article

References (40)

1. Bokoch GM. Chemoattractant signaling and leukocyte activation. Blood 1995, 86:1649-60.
2. Bokoch GM, Knaus UG. NADPH oxidases: not just for leukocytes anymore!. Trends Biochem Sci 2003, 28:502-8. 10.1016/S0968-0004(03)00194-4, 13678962.
3. Edwards SW. Biochemistry and physiology of the neutrophil. 1994, New York: Cambridge University Press, NY, USA.
4. Fu H, Karlsson J, Bylund J, Movitz C, Karlsson A, Dahlgren C. Ligand recognition and activation of formyl peptide receptors in neutrophils. J Leukoc Biol 2006, 79:247-56. 10.1189/jlb.0905498, 16365159.
5. Miller AF, Falke JJ. Chemotaxis receptors and signaling. Adv Protein Chem 2004, 68:393-444. full_text, 15500867.
6. Murphy PM. The molecular biology of leukocyte chemoattractant receptors. Annu Rev Immunol 1994, 12:593-633. 10.1146/annurev.iy.12.040194.003113, 8011292.
7. Rabiet MJ, Huet E, Boulay F. The N-formyl peptide receptors and the anaphylatoxin C5a receptors: an overview. Biochimie 2007, 89:1089-106. 10.1016/j.biochi.2007.02.015, 17428601.
8. Ye RD, Boulay F. Structure and function of leukocyte chemoattractant receptors. Adv Pharmacol 1997, 39:221-89. full_text, 9160117.
9. Heit B, Tavener S, Raharjo E, Kubes P. An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients. J Cell Biol 2002, 159:91-102. 10.1083/jcb.200202114, 2173486, 12370241.
10. Baggiolini M. Introduction to chemokines and chemokine antagonists. Ernst Schering Res Found Workshop 2004, 1-9.
11. Ye RD, Boulay F, Wang JM, Dahlgren C, Gerard C, Parmentier M, Serhan CN, Murphy AP. International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family. Pharmacol Rev 2009,
12. Boulay F, Tardif M, Brouchon L, Vignais P. Synthesis and use of a novel N-formyl peptide derivative to isolate a human N-formyl peptide receptor cDNA. Biochem Biophys Res Commun 1990, 168:1103-9. 10.1016/0006-291X(90)91143-G, 2161213.
13. Boulay F, Tardif M, Brouchon L, Vignais P. The human N-formylpeptide receptor. Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors. Biochemistry 1990, 29:11123-33. 10.1021/bi00502a016, 2176894.
14. Ye RD, Cavanagh SL, Quehenberger O, Prossnitz ER, Cochrane CG. Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor. Biochem Biophys Res Commun 1992, 184:582-9. 10.1016/0006-291X(92)90629-Y, 1374236.
15. Bellner L, Karlsson J, Fu H, Boulay F, Dahlgren C, Eriksson K, Karlsson A. A monocyte-specific peptide from herpes simplex virus type 2 glycoprotein G activates the NADPH-oxidase but not chemotaxis through a G-protein-coupled receptor distinct from the members of the formyl peptide receptor family. J Immunol 2007, 179:6080-7.
16. Rabiet MJ, Huet E, Boulay F. Human mitochondria-derived N-formylated peptides are novel agonists equally active on FPR and FPRL1, while Listeria monocytogenes-derived peptides preferentially activate FPR. Eur J Immunol 2005, 35:2486-95. 10.1002/eji.200526338, 16025565.
17. Bylund J, Christophe T, Boulay F, Nystrom T, Karlsson A, Dahlgren C. Proinflammatory activity of a cecropin-like antibacterial peptide from Helicobacter pylori. Antimicrob Agents Chemother 2001, 45:1700-4. 10.1128/AAC.45.6.1700-1704.2001, 90534, 11353614.
18. Bjorkman L, Karlsson J, Karlsson A, Rabiet MJ, Boulay F, Fu H, Bylund J, Dahlgren C. Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1. J Leukoc Biol 2008, 83:245-53. 10.1189/jlb.0607-408, 17984291.
19. Su SB, Gong W, Gao JL, Shen W, Murphy PM, Oppenheim JJ, Wang JM. A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells. J Exp Med 1999, 189:395-402. 10.1084/jem.189.2.395, 2192984, 9892621.
20. Le Y, Gong W, Tiffany HL, Tumanov A, Nedospasov S, Shen W, Dunlop NM, Gao JL, Murphy PM, Oppenheim JJ, et al. Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1. J Neurosci 2001, 21:RC123.
21. Christophe T, Karlsson A, Dugave C, Rabiet MJ, Boulay F, Dahlgren C. The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J Biol Chem 2001, 276:21585-93. 10.1074/jbc.M007769200, 11285256.
22. Hu JY, Le Y, Gong W, Dunlop NM, Gao JL, Murphy PM, Wang JM. Synthetic peptide MMK-1 is a highly specific chemotactic agonist for leukocyte FPRL1. J Leukoc Biol 2001, 70:155-61.
23. Dahlgren C, Christophe T, Boulay F, Madianos PN, Rabiet MJ, Karlsson A. The synthetic chemoattractant Trp-Lys-Tyr-Met-Val-DMet activates neutrophils preferentially through the lipoxin A(4) receptor. Blood 2000, 95:1810-8.
24. Berridge MJ. Inositol trisphosphate and calcium signalling. Nature 1993, 361:315-25. 10.1038/361315a0, 8381210.
25. Favre CJ, Nusse O, Lew DP, Krause KH. Store-operated Ca2+ influx: what is the message from the stores to the membrane?. J Lab Clin Med 1996, 128:19-26. 10.1016/S0022-2143(96)90110-9, 8759933.
26. Putney JW. Recent breakthroughs in the molecular mechanism of capacitative calcium entry (with thoughts on how we got here). Cell Calcium 2007, 42:103-10. 10.1016/j.ceca.2007.01.011, 1986648, 17349691.
27. Cunningham CC, Vegners R, Bucki R, Funaki M, Korde N, Hartwig JH, Stossel TP, Janmey PA. Cell permeant polyphosphoinositide-binding peptides that block cell motility and actin assembly. J Biol Chem 2001, 276:43390-9. 10.1074/jbc.M105289200, 11533030.
28. Fu H, Bjorkman L, Janmey P, Karlsson A, Karlsson J, Movitz C, Dahlgren C. The two neutrophil members of the formylpeptide receptor family activate the NADPH-oxidase through signals that differ in sensitivity to a gelsolin derived phosphoinositide-binding peptide. BMC Cell Biol 2004, 5:50. 10.1186/1471-2121-5-50, 545074, 15625007.
29. Partida-Sanchez S, Iribarren P, Moreno-Garcia ME, Gao JL, Murphy PM, Oppenheimer N, Wang JM, Lund FE. Chemotaxis and calcium responses of phagocytes to formyl peptide receptor ligands is differentially regulated by cyclic ADP ribose. J Immunol 2004, 172:1896-906.
30. Forsman H, Salomonsson E, Onnheim K, Karlsson J, Bjorstad A, Leffler H, Bylund J, Karlsson A, Dahlgren C. The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the agonist. Glycobiology 2008, 18:905-12. 10.1093/glycob/cwn081, 18725453.
31. Lundqvist H, Dahlgren C. Isoluminol-enhanced chemiluminescence: a sensitive method to study the release of superoxide anion from human neutrophils. Free Radic Biol Med 1996, 20:785-92. 10.1016/0891-5849(95)02189-2, 8728025.
32. Dahlgren C, Karlsson A. Respiratory burst in human neutrophils. J Immunol Methods 1999, 232:3-14. 10.1016/S0022-1759(99)00146-5, 10618505.
33. Andersson T, Dahlgren C, Pozzan T, Stendahl O, Lew PD. Characterization of fMet-Leu-Phe receptor-mediated Ca2+ influx across the plasma membrane of human neutrophils. Mol Pharmacol 1986, 30:437-43.
34. Ye RD, Boulay F, Wang JM, Dahlgren C, Gerard C, Parmentier M, Serhan CN, Murphy PM. Nomenclature for the formyl peptide receptor (FPR) family. Pharmacol Rev 2009, 2745437, 19498085.
35. Fiore S, Maddox JF, Perez HD, Serhan CN. Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor. J Exp Med 1994, 180:253-60. 10.1084/jem.180.1.253, 2191537, 8006586.
36. Gavins FN, Sawmynaden P, Chatterjee BE, Perretti M. A twist in anti-inflammation: annexin 1 acts via the lipoxin A4 receptor. Prostaglandins Leukot Essent Fatty Acids 2005, 73:211-9. 10.1016/j.plefa.2005.05.008, 15982865.
37. Karlsson J, Fu H, Boulay F, Dahlgren C, Hellstrand K, Movitz C. Neutrophil NADPH-oxidase activation by an annexin AI peptide is transduced by the formyl peptide receptor (FPR), whereas an inhibitory signal is generated independently of the FPR family receptors. J Leukoc Biol 2005,
38. Putney JW. SOC: now also store-operated cyclase. Nat Cell Biol 2009, 11:381-2. 10.1038/ncb0409-381, 19337322.
39. Putney JW, Bird GS. Cytoplasmic calcium oscillations and store-operated calcium influx. J Physiol 2008, 586:3055-9. 10.1113/jphysiol.2008.153221, 2538773, 18388136.
40. Karlsson J, Stenfeldt AL, Rabiet MJ, Bylund J, Forsman HF, Dahlgren C. The FPR2-specific ligand MMK-1 activates the neutrophil NADPH-oxidase, but triggers no unique pathway for opening of plasma membrane calcium channels. Cell Calcium 2009, 45:431-8. 10.1016/j.ceca.2009.02.002, 19282028.