Synthetic peptide MMK-1 is a highly specific chemotactic agonist for leukocyte FPRL1

Journal of Leukocyte Biology

Volumn 70, Issue 1, 2001, Pages 155-161

  Hu, Jin Yue ^a,c   Le, Yingying ^a   Gong, Wanghua ^a   Dunlop, Nancy M ^a   Gao, Ji Liang ^b   Murphy, Philip M ^b   Wang, Ji Ming ^a,d  

^a SAIC FREDERICK INC   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c CENTRAL SOUTH UNIVERSITY   (China)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Ca2+ mobilization; Chemotaxis; Cytokines; Phagocyte

Indexed keywords

CHEMOTACTIC FACTOR; FORMYLPEPTIDE; PEPTIDE DERIVATIVE; PEPTIDE MMK 1; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM MOBILIZATION; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MONOCYTE; NEUTROPHIL; PEPTIDE ANALYSIS; PHAGOCYTE; PRIORITY JOURNAL;

ANIMALS; CALCIUM; CELL LINE; CHEMOTACTIC FACTORS; CHEMOTAXIS, LEUKOCYTE; CYTOKINES; HUMANS; LEUKOCYTES, MONONUCLEAR; MICE; NEUTROPHILS; PEPTIDES; RATS; RECEPTORS, FORMYL PEPTIDE; RECEPTORS, IMMUNOLOGIC; RECEPTORS, LIPOXIN; RECEPTORS, PEPTIDE; SUBSTRATE SPECIFICITY; TRANSFECTION;

EID: 0034972383     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Chemokines and their role in tumor growth and metastasis
2. N-formylmethionyl peptides as chemoattractants for leucocytes
3. Chemokines
4. The molecular biology of leukocyte chemoattractant receptors
5. The N-formyl peptide chemotactic receptors
6. The molecular and cellular biology of the chemokines
7. Purification and identification of formyl-methionyl-leucyl-phenylalanine as the major peptide neutrophil chemotactic factor produced by Escherichia coli
8. Synthesis and use of a novel N-formyl peptide derivative to isolate a human N-formyl peptide receptor cDNA
9. Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor
10. The N-formyl peptide receptor: A model for the study of chemoattractant receptor structure and function
11. Identification of human cDNA encoding a function high affinity lipoxin A4 receptor
12. Serum amyloid A is a chemoattractant: Induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes
13. Serum amyloid A induces calcium mobilization and chemotaxis of human monocytes by activating a pertussis toxin sensitive signaling pathway
14. A seven-transmembrane, G-protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells
15. Identification of surrogate agonists for the human FPRL-1 receptor by autocrine selection in yeast
16. T21/DP107, a synthetic leucine zipper-like domain of the HIV-1 envelope gp41, attracts and activates human phagoctyes by using G-protein-coupled formyl peptide receptors
17. A synthetic peptide derived from human immunodeficiency virus type 1 gp120 downregulates the expression and function of chemokine receptors CCR5 and CXCR4 in monocytes by activating the 7-transmembrane G protein-coupled receptor FPR1/LXA4R
18. Differential expression of members of the N-formylpeptide receptor gene cluster in human phagocytes
19. T20/DP178, an ectodomain peptide of HIV-1 gp41, is a potent activator of human phagocyte N-formal peptide receptor
20. Utilization of two seven-transmembrane, G protein-coupled receptors, formyl peptide receptor-like 1 and formyl peptide receptor, by the synthetic hexapeptide WKYMVm for human phagocyte activation
21. Differential expansion of the N-formylpeptide receptor gene cluster in human and mouse
22. Activation of the chemotactic peptide receptor FPRL1 in monocytes phosphorylates the chemokine receptor CCR5 and attenuates cell responses to selected chemokines
23. Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial cell monolayers
24. Echinococcus multilocularis: Relationship between persistent inflammation, serum amyloid A protein response and amyloidosis in four mouse strains
25. Activation of lipoxin A4 receptor by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation
26. A new insight into the role of "old" chemotactic peptide receptors FPR and FPRL1: Down-regulation of chemokine receptors CCR5 and CXCR4
27. Trp-Lys-Tyr-Met-Val-D-Met stimulates superoxide generation and killing of Staphylococcus aureus via phospholipase D activation in human monocytes
28. A peptide with unique receptor specificity: Stimulation of phosphoinositide hydrolysis and induction of superoxide generation in human neutrophils
29. Identification of the peptides that stimulate the phosphoinositide hydrolysis in lymphocyte cell lines from peptide libraries