Crystal structures of human FIH-1 in complex with quinol family inhibitors

Molecules and Cells

Volumn 29, Issue 5, 2010, Pages 471-474

  Moon, Hyunjin ^a   Han, Sojung ^a   Park, Hyunsung ^a   Choe, Jungwoo ^a  

^a University of Seoul   (South Korea)

Author keywords

clioquinol; crystal structure; factor Inhibiting HIF 1 (FIH 1); hypoxia; hypoxia inducible factor 1 (HIF 1)

Indexed keywords

2 OXOGLUTARIC ACID; 8 QUINOLINOL; CLIOQUINOL; FACTOR INHIBITING HYPOXIA INDUCIBLE FACTOR 1; FERROUS ION; OXYGENASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; HUMAN; HYDROGEN BOND; PROTEIN BINDING; PROTEIN STRUCTURE;

CELL HYPOXIA; CLIOQUINOL; CRYSTALLIZATION; ENZYME INHIBITORS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KETOGLUTARIC ACIDS; MULTIPROTEIN COMPLEXES; OXYQUINOLINE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; REPRESSOR PROTEINS; SUBSTRATE SPECIFICITY;

EID: 77955056549     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10059-010-0058-3     Document Type: Article

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