-
1
-
-
0030175348
-
Contribution of the S4 segment; to gating charge in the Shaker K+ channel
-
doi:10.1016/S0896-6273(00)80143-9
-
Aggarwal, S.K., and R. MacKinnon. 1996. Contribution of the S4 segment; to gating charge in the Shaker K+ channel. Neuron. 16:1169-1177. doi:10.1016/S0896-6273(00)80143-9
-
(1996)
Neuron
, vol.16
, pp. 1169-1177
-
-
Aggarwal, S.K.1
MacKinnon, R.2
-
2
-
-
25644437209
-
Focused electric field across the voltage sensor of potassium channels
-
doi:10.1016/j.neuron.2005.08.020
-
Altern, C.A., and R. Horn. 2005. Focused electric field across the voltage sensor of potassium channels. Neuron. 48:25-29. doi:10.1016/j.neuron. 2005.08.020
-
(2005)
Neuron.
, vol.48
, pp. 25-29
-
-
Altern, C.A.1
Horn, R.2
-
3
-
-
0033014675
-
Proton and zinc effects on HERG currents
-
doi:10.1.016/S0006-3495(99)76889-X
-
Anumonwo, J.M.J. Horta, M. Delmar, S.M. Tafret, and J. Jalife. 1999. Proton and zinc effects on HERG currents. Biophys. J. 77:282-298. doi:10.1.016/S0006-3495(99)76889-X
-
(1999)
Biophys. J.
, vol.77
, pp. 282-298
-
-
Horta, A.J.M.J.1
Delmar, M.2
Tafret, S.M.3
Jalife, J.4
-
4
-
-
0017743723
-
Inactivation of the sodium channel. II. Gating current experiments
-
doi:10.1085/jgp.70.5.567
-
Armstrong, C.M., and F. Bezanilla. 1977. Inactivation of the sodium channel. II. Gating current experiments. J. Gen. Physiol. 70:567-590. doi:10.1085/jgp.70.5.567
-
(1977)
J. Gen. Physiol.
, vol.70
, pp. 567-590
-
-
Armstrong, C.M.1
Bezanilla, F.2
-
5
-
-
0032763120
-
2+and other divalent cations
-
doi:10.1085/jgp.114.6.819
-
2+ and other divalent cations. J. Gen. Physiol. 114:819-838. doi:10.1085/jgp.114.6.819
-
(1999)
J. Gen. Physiol.
, vol.114
, pp. 819-838
-
-
Cherny, V.V.1
DeCoursey, T.E.2
-
6
-
-
0028914969
-
A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
-
doi:10.10.16/0092-8674(95)90358-5
-
Curran, M.E., I. Splawski, K.W. Timothy, G.M. Vincent, E.D. Green, and M.T. Keating. 1995. A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome. Cell. 80:795-803. doi:10.10.16/0092-8674(95)90358-5
-
(1995)
Cell.
, vol.80
, pp. 795-803
-
-
Curran, M.E.1
Splawski, I.2
Timothy, K.W.3
Vincent, G.M.4
Green, E.D.5
Keating, M.T.6
-
7
-
-
54449100445
-
Disulfide locking a sodium channel voltage sensor reveals ion pair formation during activation
-
doi:10.1073/pnas.0806486105
-
DeCaen, P.G., V. Yarov-Yarovoy, Y. Zhao, T. Scheuer, and W.A. Catterall. 2008. Disulfide locking a sodium channel voltage sensor reveals ion pair formation during activation. Proc. Natl. Acad. Sci. USA. 105:15142-15147. doi:10.1073/pnas.0806486105
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 15142-15147
-
-
DeCaen, P.G.1
Yarov-Yarovoy, V.2
Zhao, Y.3
Scheuer, T.4
Catterall, W.A.5
-
8
-
-
76049115811
-
Sequential formation of ion pairs during activation of a sodium channel voltage sensor
-
doi:10.1073/pnas.0912307.106
-
DeCaen, P.G., V. Yarov-Yarovoy, E.M. Sharp, T. Scheuer, and W.A. Catterall. 2009. Sequential formation of ion pairs during activation of a sodium channel voltage sensor. Proc. Natl. Acad. Sci. USA. 106:22498-22503. doi:10.1073/pnas.0912307.106
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 22498-22503
-
-
DeCaen, P.G.1
Yarov-Yarovoy, V.2
Sharp, E.M.3
Scheuer, T.4
Catterall, W.A.5
-
9
-
-
25844437886
-
2+-induced modification of human ether-à-go-go-related gene (hERG) channel activation
-
doi:10.1113/jphysiol.2005.089094
-
2+-induced modification of human ether-à-go-go-related gene (hERG) channel activation. J. Physiol. 567:737-755. doi:10.1113/jphysiol.2005.089094
-
(2005)
J. Physiol.
, vol.567
, pp. 737-755
-
-
Fernandez, D.1
Chanta, A.2
Kinard, K.I.3
Sanguinetti, M.C.4
-
14
-
-
0032750066
-
2+) destabilization of the inactivated state
-
doi:10.1016/S0006-3495(99)77088-8
-
2+) destabilization of the inactivated state. Biophys. J. 77:2534-2541. doi:10.1016/S0006-3495(99)77088-8
-
(1999)
Biophys. J.
, vol.77
, pp. 2534-2541
-
-
Johnson Jr., J.R.1
Baiser, J.R.2
Bennett, P.B.3
-
16
-
-
0035875963
-
A novel extracellular calcium sensing mechanism in voltage-gated potassium ion channels
-
Johnson, J.P. Jr., J.R. Baiser, and P.B. Bennett. 2001. A novel extracellular calcium sensing mechanism in voltage-gated potassium ion channels. J. Neurosa. 21:4143-4153.
-
(2001)
J. Neurosa.
, vol.21
, pp. 4143-4153
-
-
Johnson Jr., J.P.1
Baiser, J.R.2
Bennett, P.B.3
-
17
-
-
20144373180
-
+ channel
-
doi:10.1124/mol.104.006577
-
+ channel. Mol. Pharmacol. 67:827-836. doi:10.1124/mol.104.006577
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 827-836
-
-
Kang, J.1
Chen, X.L.2
Wang, H.3
Ji, J.4
Cheng, H.5
Incardona, J.6
Reynolds, W.7
Viviani, F.8
Tabart, M.9
Rampe, D.10
-
18
-
-
0035936798
-
Molecular and cellular mechanisms of cardiac arrhythmias
-
doi:10.1016/S0092-8674(01)00243-4
-
Keating, M.T., and M.C. Sanguinetti. 2001. Molecular and cellular mechanisms of cardiac arrhythmias. Cell. 104:569-580. doi:10.1016/S0092-8674(01) 00243-4
-
(2001)
Cell.
, vol.104
, pp. 569-580
-
-
Keating, M.T.1
Sanguinetti, M.C.2
-
19
-
-
44349170359
-
Differences between ion binding to eag and HERG voltage sensors contribute to differential regulation of activation and deactivation gating
-
Lin, M.C., and D.M. Papazian. 2007. Differences between ion binding to eag and HERG voltage sensors contribute to differential regulation of activation and deactivation gating. Channels (Austin). 1:429-437.
-
(2007)
Channels (Austin)
, vol.1
, pp. 429-437
-
-
Lin, M.C.1
Papazian, D.M.2
-
20
-
-
0038580641
-
Negative charges in the transmembrane domains of the HERG K channel are involved in the activation-and deactivation-gating processes
-
doi:10.1085/jgp.200308788
-
Liu, J., M. Zhang, M. Jiang, and G.N. Tseng. 2003. Negative charges in the transmembrane domains of the HERG K channel are involved in the activation-and deactivation-gating processes. J. Gen. Physiol. 121:599-614. doi:10.1085/jgp.200308788
-
(2003)
J. Gen. Physiol.
, vol.121
, pp. 599-614
-
-
Liu, J.1
Zhang, M.2
Jiang, M.3
Tseng, G.N.4
-
21
-
-
0035893487
-
Effects of premature stimulation on HERG K(+) channels
-
doi:10.1113/jphysiol.2001.0.12690
-
Lu, Y., M.R Mahaut-Smith, A. Varghese, C.L. Huang, P.R. Kemp, and J.I. Vandenberg. 2001. Effects of premature stimulation on HERG K(+) channels. J. Physiol. 537:843-851. doi:10.1113/jphysiol.2001.0.12690
-
(2001)
J. Physiol.
, vol.537
, pp. 843-851
-
-
Lu, Y.1
Mahaut-Smith, M.R.2
Varghese, A.3
Huang, C.L.4
Kemp, P.R.5
Vandenberg, J.I.6
-
22
-
-
0035816728
-
Molecular interactions between two long-QT syndrome gene products, HERG and KCNE2, rationalized by in vitro and in silico analysis
-
doi:10.1161/hh1301.093633
-
Mazhari, R., J.L. Greenstein, R.L. Winslow, E. Marbán, and H.B. Nuss. 2001. Molecular interactions between two long-QT syndrome gene products, HERG and KCNE2, rationalized by in vitro and in silico analysis. Circ. Res. 89:33-38. doi:10.1161/hh1301.093633
-
(2001)
Circ. Res.
, vol.89
, pp. 33-38
-
-
Mazhari, R.1
Greenstein, J.L.2
Winslow, R.L.3
Marbán, E.4
Nuss, H.B.5
-
23
-
-
11244328061
-
v1.2 L-type calcium channels: Dissociation of effects on ionic current; and gating current
-
doi:10.1529/biophysj.104.051714
-
v1.2 L-type calcium channels: dissociation of effects on ionic current; and gating current. Biophys. J. 88:211-223. doi:10.1529/biophysj.104. 051714
-
(2005)
Biophys. J.
, vol.88
, pp. 211-223
-
-
McDonough, S.I.1
Mori, Y.2
Bean, B.R.3
-
25
-
-
35348824829
-
Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator
-
doi:10.1073/pnas.0703934104
-
Perry, M., F.B. Sachse, and M.C. Sanguinetti. 2007. Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. Proc. Natl. Acad, Sci. USA. 104:13827-13832. doi:10.1073/pnas.0703934104
-
(2007)
Proc. Natl. Acad, Sci. USA
, vol.104
, pp. 13827-13832
-
-
Perry, M.1
Sachse, F.B.2
Sanguinetti, M.C.3
-
26
-
-
0041836223
-
Gating currents associated with intramembrane charge displacement in HERG potassium channels
-
doi:10.1073/pnas.1832721100
-
Piper, D.R., A. Varghese, M.C. Sanguinetti, and M. Tristani-Firouzi. 2003. Gating currents associated with intramembrane charge displacement in HERG potassium channels. Proc. Natl. Acad. Sci. USA. 100:10534-10539. doi:10.1073/pnas.1832721100
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10534-10539
-
-
Piper, D.R.1
Varghese, A.2
Sanguinetti, M.C.3
Tristani-Firouzi, M.4
-
27
-
-
38349135764
-
Cooperative interactions between R531 and acidic residues in the voltage sensing module of hERG1 channels
-
doi:.10.1159/000113745
-
Piper, D.R., J. Rupp, F.B. Sachse, M.C. Sanguinetti, and M. TristaniFirouzi. 2008. Cooperative interactions between R531 and acidic residues in the voltage sensing module of hERG1 channels. Cell. Physiol. Biochem. 21:37-46. doi:.10.1159/000113745
-
(2008)
Cell. Physiol. Biochem.
, vol.21
, pp. 37-46
-
-
Piper, D.R.1
Rupp, J.2
Sachse, F.B.3
Sanguinetti, M.C.4
TristaniFirouzi, M.5
-
28
-
-
46149091062
-
+ channels
-
doi:10.1016/j.neuron.2008.05.006
-
+ channels. Neuron. 59:98-109. doi:10.1016/j.neuron.2008.05.006
-
(2008)
Neuron.
, vol.59
, pp. 98-109
-
-
Posson, D.J.1
Selvin, P.R.2
-
29
-
-
0004161838
-
-
2nd ed. Cambridge University Press, Cambridge
-
Press, W.H., S.A. Teukolsky, W.T. Vetterling, and B.P. Flannery. 1992. Numerical Recipes in C. 2nd ed. Cambridge University Press, Cambridge. 994 pp.
-
(1992)
Numerical Recipes in C.
-
-
Press, W.H.1
Teukolsky, S.A.2
Vetterling, W.T.3
Flannery, B.P.4
-
30
-
-
0038452402
-
2+) in metalloproteins
-
doi:10.1016/S0162-0134(98)10042-9
-
2+) in metalloproteins. J. Inorg. Biochem. 71:115-127. doi:10.1016/S0162-0134(98)10042- 9
-
(1998)
J. Inorg. Biochem.
, vol.71
, pp. 115-127
-
-
Rulísek, L.1
Vondrásek, J.2
-
31
-
-
0034116864
-
Altered gating of HERG potassium channels by cobalt and lanthanum
-
Sanchez-Chapula, J.A., and M.C. Sanguinetti. 2000. Altered gating of HERG potassium channels by cobalt and lanthanum. Pflugers Arch. 440:264-274.
-
(2000)
Pflugers Arch.
, vol.440
, pp. 264-274
-
-
Sanchez-Chapula, J.A.1
Sanguinetti, M.C.2
-
32
-
-
77955021669
-
HERG1 channelopathies
-
doi:10.1007/s00424-009-0758-8
-
Sanguinetti, M.C 2010. HERG1 channelopathies. Pflugers Arch. 460:265-276. doi:10.1007/s00424-009-0758-8
-
(2010)
Pflugers Arch.
, vol.460
, pp. 265-276
-
-
Sanguinetti, M.C.1
-
33
-
-
33645317063
-
HERG potassium channels and cardiac arrhythmia
-
doi:10.1038/nature04710
-
Sanguinetti, M.C., and M. Tristani-Firouzi. 2006. hERG potassium channels and cardiac arrhythmia. Nature. 440:463-469. doi:10.1038/nature04710
-
(2006)
Nature.
, vol.440
, pp. 463-469
-
-
Sanguinetti, M.C.1
Tristani-Firouzi, M.2
-
35
-
-
0031952461
-
Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels
-
doi: 10.1085/jgp. 111.2.313
-
Schoppa, N.E., and FJ. Sigworth. 1998. Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels. J. Gen. Physiol 111:313-342. doi: 10.1085/jgp. 111.2.313
-
(1998)
J. Gen. Physiol
, vol.111
, pp. 313-342
-
-
Schoppa, N.E.1
Sigworth, F.J.2
-
36
-
-
0026594721
-
The size of gating charge in wild-type and mutant Shaker potassium channels
-
doi:10.1126/science.1553560
-
Schoppa, N.E., K. McGormack, M.A. Tanouye, and F.J. Sigworth. 1992. The size of gating charge in wild-type and mutant Shaker potassium channels. Science. 255:1712-1715. doi:10.1126/science.1553560
-
(1992)
Science.
, vol.255
, pp. 1712-1715
-
-
Schoppa, N.E.1
McGormack, K.2
Tanouye, M.A.3
Sigworth, F.J.4
-
38
-
-
0027971204
-
Voltage gating of ion channels
-
doi:10.1017/sb033583500002894
-
Sigworth, F.J. 1994. Voltage gating of ion channels. Q. Rev. Biophys. 27:1-40. doi:10.1017/sb033583500002894
-
(1994)
Q. Rev. Biophys.
, vol.27
, pp. 1-40
-
-
Sigworth, F.J.1
-
40
-
-
0032321375
-
Cut-open oocyte voltage-clamp technique
-
P.N. Conn, editor. Academic Press, San Diego
-
Stefani, E., and. F. Bezanilla. 1998. Cut-open oocyte voltage-clamp technique. In Methods in Enzymology. P.N. Conn, editor. Academic Press, San Diego. 300-318.
-
(1998)
Methods in Enzymology.
, pp. 300-318
-
-
Stefani, E.1
Bezanilla, F.2
-
41
-
-
0026726052
-
Electrophysiological recording from Xenopus oocytes
-
doi:10.1016/0076-6879(92)07021-F
-
Stühmer, W. 1992. Electrophysiological recording from Xenopus oocytes. Methods Enzymol. 207:319-339. doi:10.1016/0076-6879(92)07021-F
-
(1992)
Methods Enzymol.
, vol.207
, pp. 319-339
-
-
Stühmer, W.1
-
42
-
-
0025736634
-
Gating currents of inactivating and non-inactivating potassium channels expressed in Xenopus oocytes
-
doi:10.1007/BF00550881
-
Stühmer, W., F. Conti, M. Stocker, O. Pongs, and S.H. Heinemann. 1991. Gating currents of inactivating and non-inactivating potassium channels expressed in Xenopus oocytes. Pflugers Arch. 418:423-429. doi:10.1007/BF00550881
-
(1991)
Pflugers Arch.
, vol.418
, pp. 423-429
-
-
Stühmer, W.1
Conti, F.2
Stocker, M.3
Pongs, O.4
Heinemann, S.H.5
-
44
-
-
0029007356
-
HERG, a human inward rectifier in the voltage-gated potassium channel family
-
doi:10.1126/science.7604285
-
Trudeau, M.C., J.W. Warmke, B. Ganetzky, and G.A. Robertson. 1995. HERG, a human inward rectifier in the voltage-gated potassium channel family. Science. 269:92-95. doi:10.1126/science.7604285
-
(1995)
Science.
, vol.269
, pp. 92-95
-
-
Trudeau, M.C.1
Warmke, J.W.2
Ganetzky, B.3
Robertson, G.A.4
-
45
-
-
0028292927
-
A family of potassium channel genes related to eag in Dmsophila and mammals
-
doi:10.1073/pnas.91.8.3438
-
Wartlike, J.W., and B. Ganetzky. 1994. A family of potassium channel genes related to eag in Dmsophila and mammals. Proc. Natl. Acad. Sci. USA. 91:3438-3442. doi:10.1073/pnas.91.8.3438
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3438-3442
-
-
Wartlike, J.W.1
Ganetzky, B.2
-
46
-
-
0028085276
-
Shaker potassium, channel gating. II: Transitions in the activation pathway
-
doi:10.1085/jgp.103.2.279
-
Zagotta, W.N., T. Hoshi, J. Dittman, and R.W. Aldrich. 1994. Shaker potassium, channel gating. II: transitions in the activation pathway. J. Gen. Physiol. 103:279-319. doi:10.1085/jgp.103.2.279
-
(1994)
J. Gen. Physiol.
, vol.103
, pp. 279-319
-
-
Zagotta, W.N.1
Hoshi, T.2
Dittman, J.3
Aldrich, R.W.4
|