Mouse model on N-acetylgalactosamine-6-sulfate sulfatase deficiency (Galns-/-) produced by targeted disruption of the gene defective in Morquio A disease

Human Molecular Genetics

Volumn 12, Issue 24, 2003, Pages 3349-3358

  Tomatsu, Shunji ^a,b   Orii, Koji O ^a,c   Vogler, Carole ^a   Nakayama, Jun ^d   Levy, Beth ^a   Grubb, Jeffrey H ^a   Gutierrez, Monica A ^a   Shim, Soomin ^a   Yamaguchi, Seiji ^b   Nishioka, Tatsuo ^a   Montaño, Adriana Maria ^a   Noguchi, Akihiko ^e   Orii, Tadao ^c   Kondo, Naomi ^c   Sly, William S ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SHIMANE UNIVERSITY   (Japan)

^c GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHONDROITIN 6 SULFATE; GLYCOSAMINOGLYCAN; KERATAN SULFATE; LYSOSOME ENZYME; N ACETYLGALACTOSAMINE 6 SULFATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; BONE MARROW; BRAIN; BRAIN REGION; CONTROLLED STUDY; CORNEA EPITHELIUM; CYTOPLASM; DISEASE MODEL; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME DEGRADATION; ENZYME REPLACEMENT; EPITHELIUM CELL; EXON; GENE DISRUPTION; GENE TARGETING; GENETIC DISORDER; GLOMERULUS; HEART; HEART VALVE; HIPPOCAMPUS; HOMOZYGOSITY; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY TUBULE EPITHELIUM; KUPFFER CELL; LIVER; LIVER CELL; LYSOSOME STORAGE DISEASE; MENINX; MORQUIO SYNDROME; MOUSE; MOUSE MUTANT; NEOCORTEX; NERVE CELL; NONHUMAN; OBSERVATION; PARENCHYMA; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RADIOGRAPHY; RETICULOENDOTHELIAL SYSTEM; SEQUENCE HOMOLOGY; SKELETON; SPLEEN; TONOPLAST; URINE; VISCERA; WILD TYPE;

ANIMALS; CHIMERA; CHONDROITINSULFATASES; DISEASE MODELS, ANIMAL; GENE TARGETING; MICE; MICE, KNOCKOUT; MUCOPOLYSACCHARIDOSIS IV; PHENOTYPE; RECOMBINATION, GENETIC; STEM CELLS;

ANIMALIA; GLOMERULUS; MURINAE;

EID: 0346752134     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddg366     Document Type: Article

References (41)

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