-
1
-
-
33847074505
-
Tumor antigen-based immunotherapy and immunoprevention of cancer
-
Ryan SO, Gantt KR, Finn OJ. Tumor antigen-based immunotherapy and immunoprevention of cancer. Int Arch Allergy Immunol 2007; 142:179-89.
-
(2007)
Int Arch Allergy Immunol
, vol.142
, pp. 179-189
-
-
Ryan, S.O.1
Gantt, K.R.2
Finn, O.J.3
-
3
-
-
34548779835
-
Deletional self-tolerance to a melanocyte/melanoma antigen derived from tyrosinase is mediated by a radio-resistant cell in peripheral and mesenteric lymph nodes
-
Nichols LA, Chen Y, Colella TA, Bennett CL, Clausen BE, Engelhard VH. Deletional self-tolerance to a melanocyte/melanoma antigen derived from tyrosinase is mediated by a radio-resistant cell in peripheral and mesenteric lymph nodes. J Immunol 2007; 179:993-1003.
-
(2007)
J Immunol
, vol.179
, pp. 993-1003
-
-
Nichols, L.A.1
Chen, Y.2
Colella, T.A.3
Bennett, C.L.4
Clausen, B.E.5
Engelhard, V.H.6
-
5
-
-
0036548986
-
Spinning molecular immunology into successful immunotherapy
-
Pardoll DM. Spinning molecular immunology into successful immunotherapy. Nat Rev Immunol 2002;2:227-38.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 227-238
-
-
Pardoll, D.M.1
-
6
-
-
1142286444
-
MUC1 immunobiology: From discovery to clinical applications
-
Vlad AM, Kettel JC, Alajez NM, Carlos CA, Finn OJ. MUC1 immunobiology: from discovery to clinical applications. Adv Immunol 2004; 82:249-93.
-
(2004)
Adv Immunol
, vol.82
, pp. 249-293
-
-
Vlad, A.M.1
Kettel, J.C.2
Alajez, N.M.3
Carlos, C.A.4
Finn, O.J.5
-
7
-
-
0025834851
-
Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells
-
Jerome KR, Barnd DL, Bendt KM, et al. Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells. Cancer Res 1991;51:2908-16.
-
(1991)
Cancer Res
, vol.51
, pp. 2908-2916
-
-
Jerome, K.R.1
Barnd, D.L.2
Bendt, K.M.3
-
8
-
-
0027321847
-
Tumor-specific cytotoxic T cell clones from patients with breast and pancreatic adenocarcinoma recognize EBV-immortalized B cells transfected with polymorphic epithelial mucin complementary DNA
-
Jerome KR, Domenech N, Finn OJ. Tumor-specific cytotoxic T cell clones from patients with breast and pancreatic adenocarcinoma recognize EBV-immortalized B cells transfected with polymorphic epithelial mucin complementary DNA. J Immunol 1993;151:1654-62.
-
(1993)
J Immunol
, vol.151
, pp. 1654-1662
-
-
Jerome, K.R.1
Domenech, N.2
Finn, O.J.3
-
9
-
-
68149088312
-
A phase I/II study of a MUC1 peptide pulsed autologous dendritic cell vaccine as adjuvant therapy in patients with resected pancreatic and biliary tumors
-
Lepisto AJ, Moser AJ, Zeh H, et al. A phase I/II study of a MUC1 peptide pulsed autologous dendritic cell vaccine as adjuvant therapy in patients with resected pancreatic and biliary tumors. Cancer Ther 2008;6:955-64.
-
(2008)
Cancer Ther
, vol.6
, pp. 955-964
-
-
Lepisto, A.J.1
Moser, A.J.2
Zeh, H.3
-
10
-
-
19944433959
-
Phase I study of a MUC1 vaccine composed of different doses of MUC1 peptide with SB-AS2 adjuvant in resected and locally advanced pancreatic cancer
-
Ramanathan RK, Lee KM, McKolanis J, et al. Phase I study of a MUC1 vaccine composed of different doses of MUC1 peptide with SB-AS2 adjuvant in resected and locally advanced pancreatic cancer. Cancer Immunol Immunother 2005;54:254-64.
-
(2005)
Cancer Immunol Immunother
, vol.54
, pp. 254-264
-
-
Ramanathan, R.K.1
Lee, K.M.2
McKolanis, J.3
-
11
-
-
34548759771
-
Cutting edge: Transgenic expression of human MUC1 in IL-10-/- mice accelerates inflammatory bowel disease and progression to colon cancer
-
Beatty PL, Plevy SE, Sepulveda AR, Finn OJ. Cutting edge: transgenic expression of human MUC1 in IL-10-/- mice accelerates inflammatory bowel disease and progression to colon cancer. J Immunol 2007;179:735-9.
-
(2007)
J Immunol
, vol.179
, pp. 735-739
-
-
Beatty, P.L.1
Plevy, S.E.2
Sepulveda, A.R.3
Finn, O.J.4
-
12
-
-
0031963862
-
Tolerance and immunity to MUC1 in a human MUC1 transgenic murine model
-
Rowse GJ, Tempero RM, VanLith ML, Hollingsworth MA, Gendler SJ. Tolerance and immunity to MUC1 in a human MUC1 transgenic murine model. Cancer Res 1998;58:315-21.
-
(1998)
Cancer Res
, vol.58
, pp. 315-321
-
-
Rowse, G.J.1
Tempero, R.M.2
VanLith, M.L.3
Hollingsworth, M.A.4
Gendler, S.J.5
-
13
-
-
33847412258
-
Lack of effective MUC1 tumor antigen-specific immunity in MUC1-transgenic mice results from a Th/T regulatory cell imbalance that can be corrected by adoptive transfer of wild-type Th cells
-
Turner MS, Cohen PA, Finn OJ. Lack of effective MUC1 tumor antigen-specific immunity in MUC1-transgenic mice results from a Th/T regulatory cell imbalance that can be corrected by adoptive transfer of wild-type Th cells. J Immunol 2007;178:2787-93.
-
(2007)
J Immunol
, vol.178
, pp. 2787-2793
-
-
Turner, M.S.1
Cohen, P.A.2
Finn, O.J.3
-
14
-
-
27744573098
-
The cooperation between two CD4 T cells induces tumor protective immunity in MUC.1 transgenic mice
-
Gerloni M, Castiglioni P, Zanetti M. The cooperation between two CD4 T cells induces tumor protective immunity in MUC.1 transgenic mice. J Immunol 2005;175:6551-9.
-
(2005)
J Immunol
, vol.175
, pp. 6551-6559
-
-
Gerloni, M.1
Castiglioni, P.2
Zanetti, M.3
-
15
-
-
53449093328
-
Targeting of antigens to B cells augments antigen-specific T-cell responses and breaks immune tolerance to tumor-associated antigen MUC1
-
Ding C, Wang L, Marroquin J, Yan J. Targeting of antigens to B cells augments antigen-specific T-cell responses and breaks immune tolerance to tumor-associated antigen MUC1. Blood 2008;112: 2817-25.
-
(2008)
Blood
, vol.112
, pp. 2817-2825
-
-
Ding, C.1
Wang, L.2
Marroquin, J.3
Yan, J.4
-
16
-
-
41149130863
-
+ T cells in anti-tumor immune responses
-
+ T cells in anti-tumor immune responses. Immunol Rev 2008;222:129-44.
-
(2008)
Immunol Rev
, vol.222
, pp. 129-144
-
-
Kennedy, R.1
Celis, E.2
-
17
-
-
10044265684
-
Glycoprotein tumor antigens for immunotherapy of breast cancer
-
Vlad AM, Finn OJ. Glycoprotein tumor antigens for immunotherapy of breast cancer. Breast Dis 2004;20:73-9.
-
(2004)
Breast Dis
, vol.20
, pp. 73-79
-
-
Vlad, A.M.1
Finn, O.J.2
-
18
-
-
0030848719
-
Immunoreactive T and Tn epitopes in cancer diagnosis, prognosis, and immunotherapy
-
Springer GF. Immunoreactive T and Tn epitopes in cancer diagnosis, prognosis, and immunotherapy. J Mol Med 1997;75:594-602.
-
(1997)
J Mol Med
, vol.75
, pp. 594-602
-
-
Springer, G.F.1
-
19
-
-
68149144929
-
Identification of Oglycosylated decapeptides within the MUC1 repeat domain as potential MHC class I (A2) binding epitopes
-
Ninkovic T, Kinarsky L, Engelmann K, et al. Identification of Oglycosylated decapeptides within the MUC1 repeat domain as potential MHC class I (A2) binding epitopes. Mol Immunol 2009;47: 131-40.
-
(2009)
Mol Immunol
, vol.47
, pp. 131-140
-
-
Ninkovic, T.1
Kinarsky, L.2
Engelmann, K.3
-
20
-
-
0037011127
-
Complex carbohydrates are not removed during processing of glycoproteins by dendritic cells: Processing of tumor antigen MUC1 glycopeptides for presentation to major histocompatibility complex class II-restricted T cells
-
Vlad AM, Muller S, Cudic M, et al. Complex carbohydrates are not removed during processing of glycoproteins by dendritic cells: processing of tumor antigen MUC1 glycopeptides for presentation to major histocompatibility complex class II-restricted T cells. J Exp Med 2002;196:1435-46.
-
(2002)
J Exp Med
, vol.196
, pp. 1435-1446
-
-
Vlad, A.M.1
Muller, S.2
Cudic, M.3
-
21
-
-
22944440380
-
Tumor-associated carbohydrate antigens: A possible avenue for cancer prevention
-
Xu Y, Sette A, Sidney J, Gendler SJ, Franco A. Tumor-associated carbohydrate antigens: a possible avenue for cancer prevention. Immunol Cell Biol 2005;83:440-8.
-
(2005)
Immunol Cell Biol
, vol.83
, pp. 440-448
-
-
Xu, Y.1
Sette, A.2
Sidney, J.3
Gendler, S.J.4
Franco, A.5
-
22
-
-
68149166302
-
Tumor-associated MUC1 glycopeptide epitopes are not subject to self-tolerance and improve responses to MUC1 peptide epitopes in MUC1 transgenic mice
-
Ryan SO, Vlad AM, Islam K, Gariépy J, Finn OJ. Tumor-associated MUC1 glycopeptide epitopes are not subject to self-tolerance and improve responses to MUC1 peptide epitopes in MUC1 transgenic mice. Biol Chem 2009;390:611-8.
-
(2009)
Biol Chem
, vol.390
, pp. 611-618
-
-
Ryan, S.O.1
Vlad, A.M.2
Islam, K.3
Gariépy, J.4
Finn, O.J.5
-
23
-
-
0026024229
-
Conserved nucleotide sequences at the 5′ end of T cell receptor variable genes facilitate polymerase chain reaction amplification
-
Broeren CP, Verjans GM, Van Eden W, Kusters JG, Lenstra JA, Logtenberg T. Conserved nucleotide sequences at the 5′ end of T cell receptor variable genes facilitate polymerase chain reaction amplification. Eur J Immunol 1991;21:569-75.
-
(1991)
Eur J Immunol
, vol.21
, pp. 569-575
-
-
Broeren, C.P.1
Verjans, G.M.2
Van Eden, W.3
Kusters, J.G.4
Lenstra, J.A.5
Logtenberg, T.6
-
24
-
-
0028946480
-
Cassette vectors directing expression of T cell receptor genes in transgenic mice
-
Kouskoff V, Signorelli K, Benoist C, Mathis D. Cassette vectors directing expression of T cell receptor genes in transgenic mice. J Immunol Methods 1995;180:273-80.
-
(1995)
J Immunol Methods
, vol.180
, pp. 273-280
-
-
Kouskoff, V.1
Signorelli, K.2
Benoist, C.3
Mathis, D.4
-
25
-
-
0024845198
-
Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a nonfunctional α-mRNA of BW5147 origin
-
Letourneur F, Malissen B. Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a nonfunctional α-mRNA of BW5147 origin. Eur J Immunol 1989;19:2269-74.
-
(1989)
Eur J Immunol
, vol.19
, pp. 2269-2274
-
-
Letourneur, F.1
Malissen, B.2
-
26
-
-
0037320932
-
Thymopoiesis independent of common lymphoid progenitors
-
Allman D, Sambandam A, Kim S, et al. Thymopoiesis independent of common lymphoid progenitors. Nat Immunol 2003;4:168-74.
-
(2003)
Nat Immunol
, vol.4
, pp. 168-174
-
-
Allman, D.1
Sambandam, A.2
Kim, S.3
-
27
-
-
0344844495
-
Nuclear magnetic resonance-based dissection of a glycosyltransferase specificity for the mucin MUC1 tandem repeat
-
Brokx RD, Revers L, Zhang Q, et al. Nuclear magnetic resonance-based dissection of a glycosyltransferase specificity for the mucin MUC1 tandem repeat. Biochemistry 2003;42:13817-25.
-
(2003)
Biochemistry
, vol.42
, pp. 13817-13825
-
-
Brokx, R.D.1
Revers, L.2
Zhang, Q.3
-
28
-
-
0035339389
-
Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC1-transgenic mice with different potential for tumor rejection
-
Soares MM, Mehta V, Finn OJ. Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC1-transgenic mice with different potential for tumor rejection. J Immunol 2001;166:6555-63.
-
(2001)
J Immunol
, vol.166
, pp. 6555-6563
-
-
Soares, M.M.1
Mehta, V.2
Finn, O.J.3
-
31
-
-
33947121146
-
Transient regulatory T-cells: A state attained by all activated human T-cells
-
Pillai V, Ortega SB, Wang CK, Karandikar NJ. Transient regulatory T-cells: a state attained by all activated human T-cells. Clin Immunol 2007;123:18-29.
-
(2007)
Clin Immunol
, vol.123
, pp. 18-29
-
-
Pillai, V.1
Ortega, S.B.2
Wang, C.K.3
Karandikar, N.J.4
-
32
-
-
0031897801
-
Defective TCR expression in transgenic mice constructed using cDNA-based α- And β-chain genes under the control of heterologous regulatory elements
-
Barnden MJ, Allison J, Heath WR, Carbone FR. Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements. Immunol Cell Biol 1998;76:34-40.
-
(1998)
Immunol Cell Biol
, vol.76
, pp. 34-40
-
-
Barnden, M.J.1
Allison, J.2
Heath, W.R.3
Carbone, F.R.4
-
33
-
-
0023663430
-
T cell tolerance by clonal elimination in the thymus
-
Kappler JW, Roehm N, Marrack P. T cell tolerance by clonal elimination in the thymus. Cell 1987;49:273-80.
-
(1987)
Cell
, vol.49
, pp. 273-280
-
-
Kappler, J.W.1
Roehm, N.2
Marrack, P.3
-
36
-
-
34248550936
-
Expression of tumor-associated differentiation antigens, MUC1 glycoforms and CEA, in human thymic epithelial cells: Implications for self-tolerance and tumor therapy
-
Cloosen S, Arnold J, Thio M, Bos GMJ, Kyewski B, Germeraad WTV. Expression of tumor-associated differentiation antigens, MUC1 glycoforms and CEA, in human thymic epithelial cells: implications for self-tolerance and tumor therapy. Cancer Res 2007;67: 3919-26.
-
(2007)
Cancer Res
, vol.67
, pp. 3919-3926
-
-
Cloosen, S.1
Arnold, J.2
Thio, M.3
Bos, G.M.J.4
Kyewski, B.5
Germeraad, W.T.V.6
-
38
-
-
0034292388
-
The mechanism of unresponsiveness to circulating tumor antigen MUC1 is a block in intracellular sorting and processing by dendritic cells
-
Hiltbold EM, Vlad AM, Ciborowski P, Watkins SC, Finn OJ. The mechanism of unresponsiveness to circulating tumor antigen MUC1 is a block in intracellular sorting and processing by dendritic cells. J Immunol 2000;165:3730-41.
-
(2000)
J Immunol
, vol.165
, pp. 3730-3741
-
-
Hiltbold, E.M.1
Vlad, A.M.2
Ciborowski, P.3
Watkins, S.C.4
Finn, O.J.5
-
39
-
-
77951074210
-
Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions
-
Fletcher AL, Lukacs-Kornek V, Reynoso ED, et al. Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions. J Exp Med 2010;207: 689-97.
-
(2010)
J Exp Med
, vol.207
, pp. 689-697
-
-
Fletcher, A.L.1
Lukacs-Kornek, V.2
Reynoso, E.D.3
-
40
-
-
54249148553
-
Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen
-
Bos R, van Duikeren S, Morreau H, et al. Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen. Cancer Res 2008;68:8446-55.
-
(2008)
Cancer Res
, vol.68
, pp. 8446-8455
-
-
Bos, R.1
Van Duikeren, S.2
Morreau, H.3
-
41
-
-
0032809534
-
Immunization of chimpanzees with tumor antigen MUC1 mucin tandem repeat peptide elicits both helper and cytotoxic T-cell responses
-
Barratt-Boyes SM, Vlad A, Finn OJ. Immunization of chimpanzees with tumor antigen MUC1 mucin tandem repeat peptide elicits both helper and cytotoxic T-cell responses. Clin Cancer Res 1999;5: 1918-24.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1918-1924
-
-
Barratt-Boyes, S.M.1
Vlad, A.2
Finn, O.J.3
-
42
-
-
49449093723
-
Deletional tolerance mediated by extrathymic Aire-expressing cells
-
Gardner JM, DeVoss JJ, Friedman RS, et al. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science 2008;321: 843-7.
-
(2008)
Science
, vol.321
, pp. 843-847
-
-
Gardner, J.M.1
DeVoss, J.J.2
Friedman, R.S.3
-
43
-
-
77951069509
-
Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
-
Cohen JN, Guidi CJ, Tewalt EF, et al. Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation. J Exp Med 2010;207:681-8.
-
(2010)
J Exp Med
, vol.207
, pp. 681-688
-
-
Cohen, J.N.1
Guidi, C.J.2
Tewalt, E.F.3
-
44
-
-
0037565445
-
Dendritic cell function in vivo during the steady state: A role in peripheral tolerance
-
Steinman RM, Hawiger D, Liu K, et al. Dendritic cell function in vivo during the steady state: a role in peripheral tolerance. Ann N Y Acad Sci 2003;987:15-25.
-
(2003)
Ann N Y Acad Sci
, vol.987
, pp. 15-25
-
-
Steinman, R.M.1
Hawiger, D.2
Liu, K.3
-
45
-
-
39749094451
-
Too dangerous to ignore: Self-tolerance and the control of ignorant autoreactive T cells
-
Parish IA, Heath WR. Too dangerous to ignore: self-tolerance and the control of ignorant autoreactive T cells. Immunol Cell Biol 2008;86: 146-52.
-
(2008)
Immunol Cell Biol
, vol.86
, pp. 146-152
-
-
Parish, I.A.1
Heath, W.R.2
-
47
-
-
27644442375
-
Protein glycosylation: Chaperone mutation in Tn syndrome
-
Ju T, Cummings RD. Protein glycosylation: chaperone mutation in Tn syndrome. Nature 2005;437:1252.
-
(2005)
Nature
, vol.437
, pp. 1252
-
-
Ju, T.1
Cummings, R.D.2
-
48
-
-
0037162490
-
Predominant selection of T cells specific for the glycosylated collagen type II epitope (263-270) in humanized transgenic mice and in rheumatoid arthritis
-
Bäcklund J, Carlsen S, Höger T, et al. Predominant selection of T cells specific for the glycosylated collagen type II epitope (263-270) in humanized transgenic mice and in rheumatoid arthritis. Proc Natl Acad Sci 2002;99:9960-5.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 9960-9965
-
-
Bäcklund, J.1
Carlsen, S.2
Höger, T.3
-
49
-
-
0035077832
-
O-Glycosylation of the mucin type
-
Hanisch F-G. O-Glycosylation of the mucin type. Biol Chem 2001; 382:143-9.
-
(2001)
Biol Chem
, vol.382
, pp. 143-149
-
-
Hanisch, F.-G.1
-
50
-
-
33749989239
-
A mutant chaperone converts a wild-type protein into a tumor-specific antigen
-
Schietinger A, Philip M, Yoshida BA, et al. A mutant chaperone converts a wild-type protein into a tumor-specific antigen. Science 2006;314:304-8.
-
(2006)
Science
, vol.314
, pp. 304-308
-
-
Schietinger, A.1
Philip, M.2
Yoshida, B.A.3
|