A mutant cheperone converts a wild-type protein into a tumor-specific antigen

Science

Volumn 314, Issue 5797, 2006, Pages 304-308

  Schietinger, Andrea ^a,b   Philip, Mary ^a   Yoshida, Barbara A ^a   Azadi, Parastoo ^c   Liu, Hui ^c   Meredith, Stephen C ^a   Schreiber, Hans ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLTRANSFERASE; MONOSACCHARIDE; MUTANT PROTEINS; SYNGENEIC MONOCLONAL ANTIBODY;

ANTIBODIES; BIOSYNTHESIS; GENES; TARGETS; TUMORS;

PROTEINS;

CHAPERONE; EPITOPE; GLYCAN DERIVATIVE; GLYCOPEPTIDE; GLYCOSYLTRANSFERASE; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; MONOSACCHARIDE; TUMOR ANTIGEN; COSMC PROTEIN, MOUSE; GALACTOSYLTRANSFERASE; GP38 PROTEIN, MOUSE; N ACETYLGALACTOSAMINE; TN ANTIGEN;

ANTIBODY; ANTIGEN; MUTATION; PROTEIN; TUMOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; COSMC GENE; GENE; GENE DISRUPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; SOMATIC MUTATION; ANIMAL; CHEMISTRY; GENETICS; GLYCOSYLATION; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION; TUMOR CELL LINE;

ACETYLGALACTOSAMINE; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ANTIGENS, NEOPLASM; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; BASE SEQUENCE; CELL LINE, TUMOR; EPITOPES; GALACTOSYLTRANSFERASES; GLYCOSYLATION; MEMBRANE GLYCOPROTEINS; MICE; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; MUTATION;

EID: 33749989239     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1129200     Document Type: Article

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