Lifespan daily locomotor activity rhythms in a mouse model of amyloid-induced neuropathology

Chronobiology International

Volumn 27, Issue 6, 2010, Pages 1159-1177

  Gorman, Michael R ^a   Yellon, Steven ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Alzheimer's disease; Amyloid plaques; Circadian; Suprachiasmatic nucleus; Tg2576; Ultradian

Indexed keywords

AMYLOID PRECURSOR PROTEIN; MUTANT PROTEIN; RECOMBINANT PROTEIN;

AGING; ALZHEIMER DISEASE; ANIMAL; ARTICLE; CIRCADIAN RHYTHM; DISEASE MODEL; GENETICS; HUMAN; LONGEVITY; MALE; METABOLISM; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; PERIODICITY; PHYSIOLOGY; SUPRACHIASMATIC NUCLEUS; TRANSGENIC MOUSE;

ACTIVITY CYCLES; AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CIRCADIAN RHYTHM; DISEASE MODELS, ANIMAL; HUMANS; LONGEVITY; MALE; MICE; MICE, TRANSGENIC; MUTANT PROTEINS; RECOMBINANT PROTEINS; SUPRACHIASMATIC NUCLEUS;

MUS; RODENTIA;

EID: 77955006508     PISSN: 07420528     EISSN: 15256073     Source Type: Journal    
DOI: 10.3109/07420528.2010.485711     Document Type: Article

References (55)

1. Ambree O, Touma C, Gortz N, Keyvani K, Paulus W, Palme R, Sachser N. (2006). Activity changes and marked stereotypic behavior precede Abeta pathology in TgCRND8 Alzheimer mice. Neurobiol. Aging 27:955-964.
2. Aujard F, Cayetanot F, Bentivoglio M, Perret M. (2006). Age-related effects on the biological clock and its behavioral output in a primate. Chronobiol. Int. 23:451-460.
3. Bateman RJ, Wen S, Morris JC, Holtzman DM. (2007). Fluctuations of CSF amyloid-p levels Implications for a diagnostic and therapeutic biomarker Neurology 68:666-669.
4. Benloucif S, Masana MI, Dubocovich ML. (1997). Light-induced phase shifts of circadian activity rhythms and immediate early gene expression in the suprachiasmatic nucleus are attenuated in old C3H/HeN mice. Brain Res. 747:34-42.
5. Davis FC, Menaker M. (1980). Hamsters through time's window: Temporal structure of hamster locomotor rhythmicity. Am. J. Physiol. 239:R149-R155.
6. Duguay D, Cermakian N. (2009). The crosstalk between physiology and clock proteins. Chronobiol. Int. 26:1479-1513.
7. Duyckaerts C, Delatour B, Potier MC. (2009). Classification and basic pathology of Alzheimer disease. Acta Neuropathol. 118:5-36.
8. Edgar DM, Kilduff TS, Martin CE, Dement WC. (1991a). Influence of running wheel activity on free-running sleep/wake and drinking circadian rhythms in mice. Physiol. Behav. 50:373-378.
9. Edgar DM, Martin CE, Dement WC. (1991b). Activity feedback to the mammalian circadian pacemaker: Influence on observed measures of rhythm period length. J. Biol. Rhythms 6:185-199.
10. Furio AM, Cutrera RA, Castillo TV, Perez LS, Riccio P, Caccuri RL, Brusco LL, Cardinali DP. (2002). Effect of melatonin on changes in locomotor activity rhythm of Syrian hamsters injected with beta amyloid peptide 25-35 in the suprachiasmatic nuclei. Cell. Mol. Neurobiol. 22:699.
11. Gil-Bea FJ, Aisa B, Schliebs R, Ramirez MJ. (2007). Increase of locomotor activity underlying the behavioral disinhibition in tg2576 mice. Behav. Neurosci. 121:340-344.
12. Goudsmit E, Hofman MA, Fliers E, Swaab DF. (1990). The supraoptic and paraventricular nuclei of the human hypothalamus in relation to sex, age and Alzheimer's disease. Neurobiol. Aging 11:529-536.
13. Harper DG, Volicer L, Stopa EG, McKee AC, Nitta M, Satlin A. (2005). Disturbance of endogenous circadian rhythm in aging and Alzheimer disease. Am. J. Geriatr. Psychiatry 13:359-368.
14. Hebert R, Dubois MF, Wolfson C, Chambers L, Cohen C. (2001). Factors associated with long-term institutionalization of older people with dementia: Data from the Canadian Study of Health and Aging. J. Gerontol. A Biol. Sci. Med. Sci. 56:M693-M699.
15. Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S. Yang F, Cole G. (1996). Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274:99-102.
16. Huitron-Resendiz S, Sánchez-Alavez M, Gallegos R, Berg G, Crawford E, Giacchino JL, Games D, Henriksen SJ, Criado JR. (2002). Age-independent and age-related deficits in visuospatial learning, sleep-wake states, thermoregulation and motor activity in PDAPP mice. Brain Res. 928:126-137.
17. Irizarry MC, McNamara M, Fedorchak K, Hsiao K, Hyman BT. (1997). APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1. J. Neuropathol. Exp. Neurol. 56:965-973.
18. Irizarry MC, Locascio JJ, Hyman BT. (2001). Beta-site APP cleaving enzyme mRNA expression in APP transgenic mice: Anatomical overlap with transgene expression and static levels with aging. Am. J. Pathol. 158:173-177.
19. Kawarabayashi T, Younkin LH, Saido TC, Shoji M, Ashe KH, Younkin SG. (2001). Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J. Neurosci. 21:372-381.
20. Klaffke S, Staedt J. (2006). Sundowning and circadian rhythm disorders in dementia. Acta Neurol. Belg. 106:168-175.
21. Lalonde R, Lewis TL, Strazielle C, Kim H, Fukuchi K. (2003). Transgenic mice expressing the betaAPP695SWE mutation: Effects on exploratory activity, anxiety, and motor coordination. Brain Res. 977:38-45. (Pubitemid 36638692)
22. LeeJH, Bliwise DL, Ansari FP, Goldstein FC, Cellar JS, LahJJ, Levey AI. (2007). Daytime sleepiness and functional impairment in Alzheimer disease. Am. J. Geriatr. Psychiatry 15:620-626.
23. Lee KW, Kim JB, Seo JS, Kim TK, Im JY, Baek IS, Kim KS, Lee JK, Han PL. (2009). Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress. J. Neurochem. 108:165-175.
24. Lewis J, Dickson DW, Lin WL, Chisholm L, Corral A, Jones G, Yen SH, Sahara N, Skipper L, Yager D, Eckman C, Hardy J, Hutton M, McGowan E. (2001). Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science 293:1487-1491.
25. Liu RY, Zhou JN, Hoogendijk WJ, van Heerikhuize J, Kamphorst W, Unmehopa UA, Hofman MA, Swaab DF. (2000). Decreased vasopressin gene expression in the biological clock of Alzheimer disease patients with and without depression. J. Neuropathol. Exp. Neurol. 59:314-322.
26. Mahlberg R, Kunz D, Sutej I, Kuhl KP, Hellweg R. (2004). Melatonin treatment of day-night rhythm disturbances and sundowning in Alzheimer disease: An open-label pilot study using actigraphy. J. Clin. Psychopharmacol. 24:456-459.
27. Martin J, Marler M, Shochat T, Ancoli-Israel S. (2000). Circadian rhythms of agitation in institutionalized patients with Alzheimer's disease. Chronobiol. Int. 17:405-418.
28. Morrissette DA, Parachikova A, Green KN, Laferla FM. (2008). Relevance of transgenic mouse models to human Alzheimer disease. J. Biol. Chem. 284:6033-6037.
29. Nagels G, Engelborghs S, Vloeberghs E, Van Dam D, Pickut BA, De Deyn PP. (2006). Actigraphic measurement of agitated behaviour in dementia. Int. J. Geriatr. Psychiatry 21:388-393.
30. Ognibene E, Middei S, Daniele S, Adriani W, Ghirardi O, Caprioli A, Laviola G. (2005). Aspects of spatial memory and behavioral disinhibition in Tg2576 transgenic mice as a model of Alzheimer's disease. Behav. Brain Res. 156:225-232.
31. Oosterman JM, van Someren EJ, Vogels RL, Van Hartens B, Scherder EJ. (2009). Fragmentation of the rest-activity rhythm correlates with age-related cognitive deficits. J. Sleep Res. 18:129-135.
32. Pang KC, Miller JP, McAuley JD. (2004). Circadian rhythms in SAMP8: A longitudinal study of the effects of age and experience. Neurobiol. Aging 25:111.
33. Penev PD, Zee PC, Turek FW. (1997). Quantitative analysis of the age-related fragmentation of hamster 24-h activity rhythms. Am. J. Physiol. 273:R2132-R2137.
34. Portaluppi F, Touitou Y, Smolensky MH. (2008). Ethical and methodological standards for laboratory and medical biological rhythm research. Chronobiol. Int. 25:999-1016.
35. Refinetti R. (2006). Circadian physiology. Boca Raton, FL: CRC Press/Taylor & Francis Group.
36. Satlin A, Teicher MH, Lieberman HR, Baldessarini RJ, Volicer L, Rheaume Y. (1991). Circadian locomotor activity rhythms in Alzheimer's disease. Neuropsychopharmacology 5:115-126.
37. Scarbrough K, Losee-Olson S, Wallen EP, Turek FW. (1997). Aging and photoperiod affect entrainment and quantitative aspects of locomotor behavior in Syrian hamsters. Am. J. Physiol. 272:R1219-R1225.
38. Selkoe DJ. (2001). Alzheimer's disease: Genes, proteins, and therapy. Physiol. Rev. 81:741-766.
39. Skene DJ, Swaab DF. (2003). Melatonin rhythmicity: Effect of age and Alzheimer's disease. Exp. Gerontol. 38:199-206.
40. Sokolove PG, Bushell WN. (1978). The chi square periodogram: Its utility for analysis of circadian rhythms. J. Theor. Biol. 72:131-160.
41. Standaert DG, Lee VM, Greenberg BD, Lowery DE, Trojanowski JQ. (1991). Molecular features of hypothalamic plaques in Alzheimer's disease. Am. J. Pathol. 139:681-691.
42. Stopa EG, Volicer L, Kuo-Leblanc V, Harper D, Lathi D, Tate B, Satlin A. (1999). Pathologic evaluation of the human suprachiasmatic nucleus in severe dementia. J. Neuropathol. Exp. Neurol. 58:29-39.
43. Swaab DF, Fliers E, Partiman TS. (1985). The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia. Brain Res. 342:37-44.
44. Tankersley CG, Irizarry R, Flanders S, Rabold R. (2002). Circadian rhythm variation in activity, body temperature, and heart rate between C3H/HeJ and C57BL/6J inbred strains. J. Appl. Physiol. 92:870-877.
45. Valentinuzzi VS, Scarbrough K, Takahashi JS, Turek FW. (1997). Effects of aging on the circadian rhythm of wheel-running activity in C57BL/6 mice. Am. J. Physiol. 273:R1957-R1964.
46. van de Nes JA, Kamphorst W, Ravid R, Swaab DF. (1998). Comparison of beta-protein/A4 deposits and Alz-50-stained cytoskeletal changes in the hypothalamus and adjoining areas of Alzheimer's disease patients: Amorphic plaques and cytoskeletal changes occur independently. Acta Neuropathol. 96:129-138.
47. van Someren EJ, Swaab DF, Colenda CC, Cohen W, McCall WV, Rosenquist PB. (1999). Bright light therapy: Improved sensitivity to its effects on rest-activity rhythms in Alzheimer patients by application of nonparametric methods. Chronobiol. Int. 16:505-518.
48. Vloeberghs E, Van Dam D, Engelborghs S, Nagels G, Staufenbiel M, De Deyn P. (2004). Altered circadian locomotor activity in APP23 mice: A model for BPSD disturbances. Eur. J. Neurosci. 20:2757-2766.
49. Volicer L, Harper DG, Manning BC, Goldstein R, Satlin A. (2001). Sundowning and circadian rhythms in Alzheimer's disease. Am. J. Psychiatry 158:704-711.
50. Wisor JP, Edgar DM, Yesavage J, Ryan HS, McCormick CM, Lapustea N, Murphy GM. (2005). Sleep and circadian abnormalities in a transgenic mouse model of Alzheimer's disease: A role for cholinergic transmission. Neuroscience 131:375-385.
51. Witting W, Kwa IH, Eikelenboom P, Mirmiran M, Swaab DF. (1990). Alterations in the circadian rest- activity rhythm in aging and Alzheimer's disease. Biol. Psychiatry 27:563-572.
52. Wu YH, Zhou JN, van Heerikhuize J, Jockers R, Swaab DF. (2007). Decreased MT1 melatonin receptor expression in the suprachiasmatic nucleus in aging and Alzheimer's disease. Neurobiol. Aging 28:1239-1247.
53. Yuede CM, Zimmerman SD, Dong H, Kling MJ, Bero AW, Holtzman DM, Timson BF, Csernansky JG. (2009). Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease. Neurobiol. Dis. 35:426-432.
54. Zelcer N, Khanlou N, Clare R, Jiang Q, Reed-Geaghan EG, Landreth GE, Vinters HV, Tontonoz P. (2007). Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors. Proc. Natl. Acad. Sci. USA 104:10601-10606.
55. Zhuo JM, Prakasam A, Murray ME, Zhang, HY, Baxter MG, Sambamurti K, Nicolle MM. (2008). An increase in Abeta42 in the prefrontal cortex is associated with a reversal-learning impairment in Alzheimer's disease model Tg2576 APPsw mice. Curr. Alzheimer Res. 5:385-391.