FAM-MDR: A flexible family-based multifactor dimensionality reduction technique to detect epistasis using related individuals

PLoS ONE

Volumn 5, Issue 4, 2010, Pages

  Cattaert, Tom ^a   Urrea, Víctor ^b   Naj, Adam C ^c   de Lobel, Lizzy ^d   de Wit, Vanessa ^a   Fu, Mao ^e   Mahachie John, Jestinah M ^a   Shen, Haiqing ^e   Luz Calle, M ^b   Ritchie, Marylyn D ^f   Edwards, Todd L ^c   van Steen, Kristel ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF VIC CENTRAL UNIVERSITY OF CATALONIA   (Spain)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d GHENT UNIVERSITY   (Belgium)

^e UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^f VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHM; AMISH; AREA UNDER THE CURVE; ARTICLE; COMPARATIVE STUDY; DATA ANALYSIS; EPISTASIS; FAMILY; FAMILY MULTIFACTOR DIMENSIONALITY REDUCTION; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC TRAIT; GENOTYPE; HUMAN; INDIVIDUALITY; MODEL BASED MULTIFACTOR DIMENSIONALITY REDUCTION; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEAR FAMILY; PARENT; PEDIGREE BASED GENERALIZED MULTIFACTOR DIMENSIONALITY REDUCTION; PHENOTYPE; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; BIOLOGICAL MODEL; BIOLOGY; COMPUTER SIMULATION; FAMILY HEALTH; GENE REGULATORY NETWORK; GENETIC EPISTASIS; GENETICS; METHODOLOGY; PEDIGREE; VALIDATION STUDY;

COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DIABETES MELLITUS, TYPE 2; EPISTASIS, GENETIC; FAMILY HEALTH; GENE REGULATORY NETWORKS; HUMANS; MODELS, GENETIC; PEDIGREE;

EID: 77954972153     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010304     Document Type: Article

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