Effect of the I to activator NS5806 on cloned K v4 channels depends on the accessory protein KChIP2

British Journal of Pharmacology

Volumn 160, Issue 8, 2010, Pages 2028-2044

  Lundby, A ^a   Jespersen, T ^a   Schmitt, N ^a   Grunnet, M ^a,b   Olesen, S P ^a,b   Cordeiro, Jm ^c   Calloe, K ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NEUROSEARCH A S   (Denmark)

^c MASONIC MEDICAL RESEARCH LABORATORY   (United States)

Author keywords

DPP6; I to; K V1.4; K V4.3; KChIP2; KCNE; NS5806; transient outward potassium current

Indexed keywords

1 [2,4 DIBROMO 6 (1H TETRAZOL 5 YL)PHENYL] 3 (3,5 BISTRIFLUOROMETHYLPHENYL)UREA; NS 5806; POTASSIUM CHANNEL KCNE2; POTASSIUM CHANNEL KCNE3; POTASSIUM CHANNEL KIR2; POTASSIUM CHANNEL KV1.4; POTASSIUM CHANNEL KV11.1; POTASSIUM CHANNEL KV4.2; POTASSIUM CHANNEL KV4.3; POTASSIUM CHANNEL KV7.1; POTASSIUM CHANNEL STIMULATING AGENT; PROTEIN DPP10; PROTEIN DPP6; PROTEIN KCHIP2; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL 4; 1-(3,5-BIS-TRIFLUOROMETHYLPHENYL)-3-(2,4-DIBROMO-6-(1H-TETRAZOL-5-YL)PHENYL)UREA; CARBANILAMIDE DERIVATIVE; DIPEPTIDYL PEPTIDASE; DPP10 PROTEIN, HUMAN; DPP6 PROTEIN, HUMAN; KCND1 PROTEIN, HUMAN; KCND2 PROTEIN, HUMAN; KCND3 PROTEIN, HUMAN; KCNE2 PROTEIN, HUMAN; KCNE3 PROTEIN, HUMAN; KCNIP2 PROTEIN, HUMAN; KV CHANNEL INTERACTING PROTEIN; NERVE PROTEIN; POTASSIUM; POTASSIUM CHANNEL; SHAL POTASSIUM CHANNEL; TETRAZOLE DERIVATIVE;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DOG; DRUG EFFECT; FEMALE; HEART VENTRICLE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; XENOPUS LAEVIS; ANIMAL; CHO CELL LINE; CRICETULUS; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; KINETICS; MEMBRANE POTENTIAL; METABOLISM;

ANIMALS; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; CRICETULUS; DIPEPTIDYL-PEPTIDASES AND TRIPEPTIDYL-PEPTIDASES; HUMANS; ION CHANNEL GATING; KINETICS; KV CHANNEL-INTERACTING PROTEINS; KV1.4 POTASSIUM CHANNEL; MEMBRANE POTENTIALS; NERVE TISSUE PROTEINS; PHENYLUREA COMPOUNDS; POTASSIUM; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; SHAL POTASSIUM CHANNELS; TETRAZOLES; TRANSFECTION; XENOPUS LAEVIS;

EID: 77954878828     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00859.x     Document Type: Article

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