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Volumn 32, Issue 5, 2010, Pages 821-843

Plerixafor: A chemokine receptor-4 antagonist for mobilization of hematopoietic stem cells for transplantation after high-dose chemotherapy for non-hodgkin's lymphoma or multiple myeloma

Author keywords

AMD3100; CXCR4; Hematopoietic stem cells; Lymphoma; Multiple myeloma; Plerixafor; SDF 1

Indexed keywords

CHEMOKINE RECEPTOR ANTAGONIST; CYCLOPHOSPHAMIDE; GRANULOCYTE COLONY STIMULATING FACTOR; PLERIXAFOR; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

EID: 77954804850     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2010.05.007     Document Type: Article
Times cited : (48)

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    • Hess DA, Wirthlin L, Craft TP, et al. Human CD34+ cells mobilized by AMD3100 demonstrate enhanced NOD/SCID repopulating function compared to CD34+ cells mobilized by granulocyte colony stimulating factor. Blood (ASH Annual Meeting Abstracts) 2005, 106. Abstract 1962. Accessed July 10, 2009. http://www.abstracts.hematologylibrary.org/cgi/content/abstract/106/11/1962.
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    • A comparison of the ability of AMD3100 versus G-CSF to induce angiogenesis and mobilize endothelial progenitor cells (EPCs)
    • Abstract 3597. Accessed July 10, 2009
    • Capoccia BJ, Shepherd RM, Guven H, et al. A comparison of the ability of AMD3100 versus G-CSF to induce angiogenesis and mobilize endothelial progenitor cells (EPCs). Blood (ASH Annual Meeting Abstracts) 2004, 104. Abstract 3597. Accessed July 10, 2009. http://www.abstracts.hematologylibrary.org/cgi/content/abstract/104/11/3597.
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    • G-CSF and AMD3100 mobilize angiogenic cells into the blood that stimulate angiogenesis in vivo through a paracrine mechanism
    • Abstract 188. Accessed July 10, 2009
    • Capoccia BJ, Shepherd RM, Link DC G-CSF and AMD3100 mobilize angiogenic cells into the blood that stimulate angiogenesis in vivo through a paracrine mechanism. Blood (ASH Annual Meeting Abstracts) 2005, 106. Abstract 188. Accessed July 10, 2009. http://www.abstracts.hematologylibrary.org/cgi/content/abstract/106/11/188.
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    • Abstract 568. Accessed July 10, 2009
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    • AMD3100 mobilizes acute promyelocytic leukemia cells from the bone marrow into the peripheral blood and sensitizes leukemia cells to chemotherapy
    • Abstract 246. Accessed July 10, 2009
    • Nervi B, Holt M, Rettig MP, et al. AMD3100 mobilizes acute promyelocytic leukemia cells from the bone marrow into the peripheral blood and sensitizes leukemia cells to chemotherapy. Blood (ASH Annual Meeting Abstracts) 2005, 106. Abstract 246. Accessed July 10, 2009. http://www.abstracts.hematologylibrary.org/cgi/content/abstract/106/11/246.
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  • 100
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    • Kinetics of human and murine mobilization of acute myeloid leukemia in response to AMD3100
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    • Mobilization of normal mouse progenitors and acute promyelocytic leukemia (APL) cells with inhibitors of CXCR4 and VLA-4 in splenectomized and unsplenectomized mice
    • Abstract 2219. Accessed July 10, 2009
    • Ramirez PA, Holt M, Rettig MP, et al. Mobilization of normal mouse progenitors and acute promyelocytic leukemia (APL) cells with inhibitors of CXCR4 and VLA-4 in splenectomized and unsplenectomized mice. Blood (ASH Annual Meeting Abstracts) 2007, 110. Abstract 2219. Accessed July 10, 2009. http://www.abstracts.hematologylibrary.org/cgi/content/abstract/110/11/2219.
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    • The CXCR4 antagonist, AMD3100, inhibits AML transmi-gratory activity but does not alter blast proliferation or survival
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    • CXCR4 antagonists mobilize acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment in mice
    • Abstract 4592. Accessed July 10, 2009
    • Juarez J, Hewson J, Cisterne A, et al. CXCR4 antagonists mobilize acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment in mice. Blood (ASH Annual Meeting Abstracts) 2005, 106. Abstract 4592. Accessed July 10, 2009. http://www.abstracts.hematologylibrary.org/cgi/content/abstract/106/11/4592.
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    • Juarez, J.1    Hewson, J.2    Cisterne, A.3
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    • AMD3100 inhibits chemotaxis towards SDF-1 and CXCR4-mediated stroma-contact in a dose-dependent manner, resulting in increased susceptibility to imatinib
    • Abstract 4799. Accessed July 10, 2009
    • Dillmann FM, Veldwijk MR, Calandra G, et al. AMD3100 inhibits chemotaxis towards SDF-1 and CXCR4-mediated stroma-contact in a dose-dependent manner, resulting in increased susceptibility to imatinib. Blood (ASH Annual Meeting Abstracts) 2006, 108. Abstract 4799. Accessed July 10, 2009. http://www.abstracts.hematologylibrary.org/cgi/content/abstract/108/11/4799.
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    • Dillmann, F.M.1    Veldwijk, M.R.2    Calandra, G.3
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    • The role of the CXCR4 inhibitor AMD3100 in multiple myeloma (MM)
    • Abstract 2492. Accessed July 10, 2009
    • Ghobrial IM, Melhem M, Singha U, et al. The role of the CXCR4 inhibitor AMD3100 in multiple myeloma (MM). Blood (ASH Annual Meeting Abstracts) 2005, 106. Abstract 2492. Accessed July 10, 2009. http://www.abstracts.hematologylibrary.org/cgi/content/abstract/106/11/2492.
    • (2005) Blood (ASH Annual Meeting Abstracts) , pp. 106
    • Ghobrial, I.M.1    Melhem, M.2    Singha, U.3
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    • In vivo mobilization of multiple myeloma cells out of the bone marrow using the CXCR4 inhibitor AMD3100 and bortezomib: Implications for sensitization of myeloma cells to apoptosis
    • Abstract 2501. Accessed July 10, 2009
    • Runnels JM, Azab A, Pitsillides C, et al. In vivo mobilization of multiple myeloma cells out of the bone marrow using the CXCR4 inhibitor AMD3100 and bortezomib: Implications for sensitization of myeloma cells to apoptosis. Blood (ASH Annual Meeting Abstracts) 2007, 110. Abstract 2501. Accessed July 10, 2009. http://www.abstracts.hematologylibrary.org/cgi/content/abstract/110/11/2501.
    • (2007) Blood (ASH Annual Meeting Abstracts) , pp. 110
    • Runnels, J.M.1    Azab, A.2    Pitsillides, C.3
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    • CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy
    • Azab AK, Runnels JM, Pitsillides C, et al. CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy. Blood. 2009, 113:4341-4351.
    • (2009) Blood. , vol.113 , pp. 4341-4351
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    • The CXCR4/SDF-1 axis regulates migration and adhesion in waldenstrom macroglobulinemia
    • Abstract 2418. Accessed July 10, 2009
    • Ngo H, Hatjiharissi E, Leleu X, et al. The CXCR4/SDF-1 axis regulates migration and adhesion in waldenstrom macroglobulinemia. Blood (ASH Annual Meeting Abstracts) 2006, 108. Abstract 2418. Accessed July 10, 2009. http://www.abstracts.hematologylibrary.org/cgi/content/abstract/108/11/2418.
    • (2006) Blood (ASH Annual Meeting Abstracts) , pp. 108
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    • Bortezomib administered pre-au-to-SCT and as maintenance therapy post transplant for multiple myeloma: A single institution phase II study
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    • (2009) Bone Marrow Transplant. , vol.43 , pp. 793-800
    • Uy, G.L.1    Goyal, S.D.2    Fisher, N.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.