A pharmacokinetic-pharmacodynamic model for the mobilization of CD34 + hematopoietic progenitor cells by AMD3100

Clinical Pharmacology and Therapeutics

Volumn 77, Issue 5, 2005, Pages 427-436

  Lack, N A ^b   Green, B ^b   Dale, D C ^b   Calandra, G B ^b   Lee, H ^b   MacFarland, R T ^a   Badel, K ^b   Liles, W C ^b   Bridger, G ^b  

^a GENZYME CORPORATION   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); CD34 ANTIGEN; HETEROCYCLIC COMPOUND;

ADULT; ARTICLE; BLOOD; BONE MARROW; CD34 SELECTION; CELL COUNT; CELL MOTILITY; CLINICAL TRIAL; COMPARTMENT MODEL; COMPUTER PROGRAM; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFECT; DRUG SAFETY; FEMALE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MALE; MATHEMATICAL MODEL; NORMAL HUMAN; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; REGRESSION ANALYSIS; SIDE EFFECT; SINGLE DRUG DOSE; ALGORITHM; CELL MOTION; CYTOLOGY; DOSE RESPONSE; DRUG ADMINISTRATION; LEUKOCYTE COUNT; METHODOLOGY; PHASE 3 CLINICAL TRIAL; PHYSIOLOGY; SUBCUTANEOUS DRUG ADMINISTRATION;

ADULT; ALGORITHMS; ANTIGENS, CD34; CELL MOVEMENT; CLINICAL TRIALS, PHASE III; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; HEMATOPOIETIC STEM CELLS; HETEROCYCLIC COMPOUNDS; HUMANS; INJECTIONS, SUBCUTANEOUS; LEUKOCYTE COUNT; MALE;

EID: 19144361854     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clpt.2004.12.268     Document Type: Article

References (29)

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