Autologous peripheral blood progenitor cell transplantation with <2×106 CD34+/kg: An analysis of variables concerning mobilisation and engraftment

Hematology Journal

Volumn 1, Issue 6, 2000, Pages 374-381

  Villalón, Lucía ^a   Odriozola, Jesús ^a   Laraña, José García ^a   Zamora, Concepción ^a   De Oteyza, Jaime Pérez ^a   Jodra, Manuel Hernández ^a   López, Javier ^a   Herrera, Pilar ^a   Roldán, Ernesto ^a   Ramos, Maria Luz ^a   Ramos, Paloma ^a   Navarro, José Luis ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

Autologous PBPCT; Engraftment; Mobilisation

Indexed keywords

ANTINEOPLASTIC AGENT; CASP14 PROTEIN, HUMAN; CASPASE; CASPASE 14; CD34 ANTIGEN; CYCLOPHOSPHAMIDE; CYTARABINE; ERYTHROPOIETIN; ETOPOSIDE; GRANULOCYTE COLONY STIMULATING FACTOR; HYDROXYUREA;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOTRANSPLANTATION; BLOOD CELL COUNT; BLOOD DISEASE; BRAIN HEMORRHAGE; COHORT ANALYSIS; FEMALE; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFECTION; LEUKAPHERESIS; LIFE TABLE; MALE; METHODOLOGY; MIDDLE AGED; MORTALITY; MULTIMODALITY CANCER THERAPY; NEOPLASM; PROPORTIONAL HAZARDS MODEL; STATISTICS; STEM CELL MOBILIZATION;

ADOLESCENT; ADULT; AGED; ANTIGENS, CD34; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BLOOD CELL COUNT; CASPASE 14; CASPASES; CEREBRAL HEMORRHAGE; COHORT STUDIES; COMBINED MODALITY THERAPY; CYCLOPHOSPHAMIDE; CYTARABINE; ERYTHROPOIETIN; ETOPOSIDE; FEMALE; GRAFT SURVIVAL; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; HYDROXYUREA; INFECTION; LEUKAPHERESIS; LIFE TABLES; MALE; MIDDLE AGED; NEOPLASMS; PROPORTIONAL HAZARDS MODELS; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, AUTOLOGOUS;

EID: 0034585611     PISSN: 14664860     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.thj.6200057     Document Type: Article

References (18)

1. To LB, Haylock DN, Simmons PJ, Juttner CA. The biology and clinical uses of blood stem cells. Blood 89: 2233, 1997.
2. To LB, Roberts MM, Haylock DN, Dyson PG, Brandford AL, Thorp D, Ho JQK, Dart GW, Horwath N, Davy MLJ, Olweny CLM, Abdi E, Juttner CA. Comparison of hematological recovery times and supportive care requirement of autologous recovery phase peripheral blood stem cell transplant, autologous bone marrow transplant and allogeneic bone marrow transplants. Bone Marrow Transplant 9: 277, 1992.
3. Siena B, Bregni M, Brando B, Belli N, Ravagnani F, Gandola L, Stern AC, Lansdorp PM, Bonadonna G, Gianni M. Flow cytometry for clinical estimation of circulating haematopoietic progenitors for autologous transplantation in cancer patients. Blood 77: 400, 1991.
4. Bensinger W, Appelbaum F, Rowly S, Storb R, Sanders J, Lilleby K, Gooley T, Derimer T, Schiffman K, Weaver C, Clift R, Chauncey T, Klarnet J, Montgomery P, Pertersdorf S, Weiden P, Witherspoon R, Buckner CD. Factors that influence collection and engraftment of autologous peripheral-blood stem cells. Journal of Clinical Oncology 13: 2547, 1995.
5. Schiller G, Vescio R, Freytes C, Spitzer G, Sahabi F, Lee M, Hua Wu C, Cao J, Lee JC, Hong CH, Lichtenstein A, Lill M, Berenson R, Berenson J. Transplantation of CD34+ peripheral blood progenitor cells after high-dose chemotherapy for patients with advanced multiple myeloma. Blood 86: 390, 1995.
6. Bensinger WI, Longin K, Applebaum F, Rowley S, Weaver C, Lilleby K, Gooley T, Lynch M, Higano T, Klarnet J, Chauncey T, Storb R, Buckner CD. Peripheral blood stem cells (PBSCs) collected after recombinant granulocyte colony stimulating factor (rhG-CSF): an analysis of factors correlating with the tempo of engraftment after transplantation. British Journal of Haematology 87: 825, 1994.
7. Watts MJ, Sullivan AM, Leverett D, Peniket J, Perry AR, Williams CD, Deveraux S, Goldstone AH, Linch DC. Back-up bone marrow is frequently ineffective in patients with poor peripheral blood stem cell mobilisation. Journal of Clinical Oncology 16: 1554, 1998.
8. Gandhi MK, Jestice K, Scott MA, Bloxham D, Bass G, Marcus RE. The minimum CD34 threshold depends on prior chemotherapy in autologous peripheral blood stem cells recipients. Bone Marrow Transplant 23: 9, 1999.
9. Tricot G, Jagannath S, Vesole D, Nelson J, Tindle S, Miller L, Cheson B, Crowley J, Barlogie B. Peripheral stem cell transplantation for multiple myeloma: identification of favorable variables for rapid engraftment in 225 patients. Blood 85: 588, 1995.
10. Weaver CH, Hazelton B, Birch R, Palmer P, Allen C, Schwatzberg L, West W. An analysis of engraftment kinetics as a function of CD34 content of peripheral blood progenitor cell collections in 692 patients after the administration of myeloablative chemotherapy. Blood 86: 3961, 1995.
11. Lie AK, Rawling TP, Bayly JI, To JB. Progenitor cell yield in sequential blood stem cell mobilisation in the same patients: insights into chemotherapy dose escalation and combination of haematopoietic growth factor and chemotherapy. British Journal of Haematology 95: 39, 1996.
12. Ketterer N, Salles G, Moullet I, Dumontet C, ElJaafari-Corbin A, Tremisi P, Thieblemont C, Durand B, Neidhart-Berard EV, Samaha H, Rigal D, Coiffier B. Factors associated with successful mobilisation of peripheral blood progenitor cells in 200 patients with lymphoid malignancies. British Journal of Haematology 103: 235, 1998.
13. Desikan R, Barlogie B, Jagannath S, Vesole DH, Siegel D, Fassas A, Munshi N, Singhal S, Mehta J, Tindle S, Nelson J, Bracy D, Mattox S, Tricot G. Comparable engraftment kinetics following peripheral-blood stem-cell infusion mobilised with granulocyte colony-stimulating factor with or without cyclophosphamide in multiple myeloma. Journal of Clinical Oncology 16: 1547, 1998.
14. Alegre A, Tomás JF, Martínez-Chamorro C, Gil-Fernández JJ, Fernández-Villalta MJ, Arranz R, Díaz MA, Granda A, Bernardo MR, Escudero A, López-Lorenzo JL, Fernández-Rañada JM. Comparison of peripheral blood progenitor cell mobilisation in patients with multiple myeloma: high-dose cyclophosphamide plus GM-CSF vs G-CSF alone. Bone Marrow Transplant 20: 211, 1997.
15. + counts decrease hematologic toxicity of autologous peripheral blood progenitor cell transplantation. Blood 91: 3148, 1998.
16. Dreger P, Kloos M, Petersen R, Haferlach T, Loffler H, Loeffler M, Schmitz N. Autologous progenitor cell transplantation: prior exposure to stem cell-toxic drugs determines yield and engraftment of peripheral blood progenitor cell but not of bone marrow grafts. Blood 86: 3970, 1995.
17. Carlo-Stella C, Tabilio A, Regazzi E, Garau D, La Tagliata R, Trasarti S, Andrizzi C, Vignetti M, Meloni G. Effect of chemotherapy for acute myelogenous leukemia on haematopoietic and fibroblast marrow progenitors. Bone Marrow Transplant 20: 465, 1997.
18. Carella A, Lerma E, Corsetti M, Dejana A, Basta P, Vassallo F, Abate M, Soracco M, Benvenuto F, Figari O, Podestá M, Piaggio G, Ferrara R, Sessagaro M, Parodi C, Pizzuti M, Rubagotti A, Occhini D, Frassoni F. Autografting with Philadelphia chromosome-negative mobilised haematopoietic progenitor cells in chronic myelogeneous leukemia. Blood 93: 1534, 1999.